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VTTAGTRFSAITRTAAQTRVLDAALDLISEHGVSGTSLQMIADSMGVTKAAVYRQFKSKDDIVIALTERE FGRLEDALEAAEAEESAPRARELLLNQVIDEAIERRRHVATLQFDPVIIKFLASHQPFQAFIARLYAVLV GDAGREAKLTAAMLSGAIAVGVMHPLVADIDDDTLRRELLHYTRRLIDLPE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4249 | - | - | 100% (191) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1613 | - | 3e-27 | 37.99% (179) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0170 | - | 5e-19 | 35.05% (194) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0244 | - | 3e-07 | 30.34% (89) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0973 | - | 5e-20 | 32.61% (184) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0238 | - | 3e-07 | 30.34% (89) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-07 | 28.40% (81) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3883c | - | 6e-08 | 33.66% (101) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4699 | - | 3e-66 | 67.57% (185) | transcriptional regulatory protein |
| M. avium 104 | MAV_0959 | - | 8e-57 | 58.15% (184) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0227 | - | 8e-35 | 44.81% (183) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2336 | - | 6e-20 | 32.45% (188) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4787 | - | 7e-08 | 30.93% (97) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4249|M.vanbaalenii_PYR-1 -----------------------MTTAG-TRFSAITRTAAQTRVLDAALD
MMAR_4699|M.marinum_M -----------------------MSSQSRNQFRVITRSAAQVRILDATLG
MAV_0959|M.avium_104 -------------------MGTARQAVSDEQFWLVEHSPARTRVLDAALD
MSMEG_0227|M.smegmatis_MC2_155 ------------------------MAKS-----VAPRGFARERVLEAALN
Mflv_0973|M.gilvum_PYR-GCK ----------------------------MSGDSTRAGGPTRRRLIDVAIE
TH_2336|M.thermoresistible__bu --------------VSGVGKPISREAALLTSRASAGTGPTRQRLIEVAIE
Mb0244|M.bovis_AF2122/97 ---------------------------MAGGTKRLPRAVREQQMLDAAVQ
Rv0238|M.tuberculosis_H37Rv ---------------------------MAGGTKRLPRAVREQQMLDAAVQ
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MAB_3883c|M.abscessus_ATCC_199 ---------------MAPLVDAGGGVTVQAMDAQASADPVTERILDAALS
MUL_4787|M.ulcerans_Agy99 -----------MNERTPSSRPHRSSRSRDSPSREERKEATRRAIIAAALK
:: .:
Mvan_4249|M.vanbaalenii_PYR-1 LISEHGVSGTSLQMIADSMGVTKAAVYRQFKSKDDIVIALTEREFGRLED
MMAR_4699|M.marinum_M LIAEHGVGGTSLQMIADAVGVTKAAVYHQFKTKEQIVIALTERELGGLEE
MAV_0959|M.avium_104 LFAANGVSGTSLQMIADAVGITKAAVYHQFRTKEQIVIAVTERELGRLVP
MSMEG_0227|M.smegmatis_MC2_155 LFAEHGVNGTSLQMIADRLGVSKAAVYYQFHSKDDIVFAVVEPIFGDMRR
Mflv_0973|M.gilvum_PYR-GCK LFKRYSVAGTSLQMISDELGLTKSAIYHHFRTRDELLTAVMEPLIAEVAE
TH_2336|M.thermoresistible__bu LFKQHSVAGTSLQMISDALGLTKSAIYHHFRTRDELLTAVMEPLISEVAE
Mb0244|M.bovis_AF2122/97 MFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFID
Rv0238|M.tuberculosis_H37Rv MFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFID
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
MAB_3883c|M.abscessus_ATCC_199 CVTEFGVRRTTLVEVAKRAGVSRPSVYRRWPDVRTLVAELLTREMGSILP
MUL_4787|M.ulcerans_Agy99 LVHDRSFSALSLREVTREAGIVPAAFYRHFESMEALGLVLIDESFRTLRD
. . : :: : . .* : : : .
Mvan_4249|M.vanbaalenii_PYR-1 ALEAAEAEESAPR--ARELLLNQVIDEAIERRRHVATLQFDPVIIKFLAS
MMAR_4699|M.marinum_M ALEAAEAHDHPSQ--ARELLLDRVIELAVERRGAASTLQFDPVIVRLLAE
MAV_0959|M.avium_104 ALEEAEAHDDGPQ--ARDALLVRVIEMAVRDRRLVRTLQFDPVVVRLLAE
MSMEG_0227|M.smegmatis_MC2_155 VLRIAEAMSSPDA--RREAAVSGMVELAVRHRRVSAVFHGDPAIDNLVHS
Mflv_0973|M.gilvum_PYR-GCK IVDAAEEQRTPHA--RADHMLVGYASIAARHRTLIPLLSGDPGVVALLRT
TH_2336|M.thermoresistible__bu IVSAAEARRGART--RADHFLRGYAALAAAHREVISLLTGDPGVVALLRT
Mb0244|M.bovis_AF2122/97 ALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHT
Rv0238|M.tuberculosis_H37Rv ALRSSINFDQSPKDLLRNTIVSFLRYIDANRASWIVMYTQATSSQAFAHT
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
MAB_3883c|M.abscessus_ATCC_199 ATGRGCARERLVR------SVTGLVTQVREHSIFAAILRSDPELLLTYIV
MUL_4787|M.ulcerans_Agy99 TLRGARAGRLDPNRVIESSVEILIGSVAERREHWRFIVRERSTGLSVLRY
.
Mvan_4249|M.vanbaalenii_PYR-1 HQ--PFQAFIARLYAVLVG------DAGREAKLTAAMLSGAIAVGVMHPL
MMAR_4699|M.marinum_M HQ--PFQRFIERLYGVLIG------DAGQDTRVLAAMLSGAIAVGVLHPL
MAV_0959|M.avium_104 HE--PFQRFMDRLYRVLLS------DAGLDGRIEAAMFSGALSTAVMHPL
MSMEG_0227|M.smegmatis_MC2_155 RK--DLHEVIERLTAILLGP-----EPGTACRVMMSMLASGIFSSAMDPE
Mflv_0973|M.gilvum_PYR-GCK RS--EWGDLVRRQLALFSEV-----EPGLGGQVKAALAMSGIASAAGVDY
TH_2336|M.thermoresistible__bu RP--DWAEVVQRQMALLGDV-----QPGPGGRVKAAVVMAGIAAAAGVDY
Mb0244|M.bovis_AF2122/97 VR--EGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLG
Rv0238|M.tuberculosis_H37Rv VR--EGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLG
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALISADSR---LDPHRARMVAVGLVGISVDCARYWL
MAB_3883c|M.abscessus_ATCC_199 QRLGTSQRALIGWTAMLIVEG----QADGSIRAGIPEQMAAMVLLIGQSV
MUL_4787|M.ulcerans_Agy99 AIRTDIRLITSELATDLARFPGLNEWSTEDLNILATMFVNAMIVTAEAIE
: .
Mvan_4249|M.vanbaalenii_PYR-1 VA--DIDDDTLRRELLHYTRR-LIDLPE----------
MMAR_4699|M.marinum_M VA--DVDDATLRTQLRRITSR-LMDTGEG---------
MAV_0959|M.avium_104 VV--DIDDETLLDRVTDLSRR-LLGLPRKPVE------
MSMEG_0227|M.smegmatis_MC2_155 LA--DIDDEELHRVLLDCTQR-LLNAPVSS--------
Mflv_0973|M.gilvum_PYR-GCK GG--DVDDDTLRDQLIAAGRR-ALGLRNSRTGAVTARR
TH_2336|M.thermoresistible__bu G---DLDEAALRDELLAAGRR-TLGLR-----APHARG
Mb0244|M.bovis_AF2122/97 IG--DTDVDEAAEMMINLFWLGLKGAPVDRLETGH---
Rv0238|M.tuberculosis_H37Rv IG--DTDVDEAAEMMINLFWLGLKGAPVDRLETGH---
MLBr_00815|M.leprae_Br4923 DTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-------
MAB_3883c|M.abscessus_ATCC_199 LQSARIVADILSPDELVDELATAIDGYLKA--------
MUL_4787|M.ulcerans_Agy99 DAQSSEALEEIRRIAVKQLRMVAIGVAGWKSRP-----