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SGDSTRAGGPTRRRLIDVAIELFKRYSVAGTSLQMISDELGLTKSAIYHHFRTRDELLTAVMEPLIAEVA EIVDAAEEQRTPHARADHMLVGYASIAARHRTLIPLLSGDPGVVALLRTRSEWGDLVRRQLALFSEVEPG LGGQVKAALAMSGIASAAGVDYGGDVDDDTLRDQLIAAGRRALGLRNSRTGAVTARR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0973 | - | - | 100% (198) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4630 | - | 1e-09 | 34.21% (152) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2461 | - | 9e-09 | 27.59% (174) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 6e-10 | 26.70% (176) | TetR/ACRR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 3e-10 | 26.70% (176) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00949 | - | 4e-05 | 29.11% (79) | hypothetical protein MLBr_00949 |
| M. abscessus ATCC 19977 | MAB_2677c | - | 5e-12 | 25.71% (175) | putative trancscriptional regulator,TetR |
| M. marinum M | MMAR_4699 | - | 3e-18 | 32.93% (164) | transcriptional regulatory protein |
| M. avium 104 | MAV_0959 | - | 2e-25 | 37.78% (180) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6537 | - | 1e-47 | 50.26% (189) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2336 | - | 3e-70 | 73.60% (178) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0293 | - | 6e-18 | 37.18% (156) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0170 | - | 8e-46 | 49.44% (178) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0973|M.gilvum_PYR-GCK --------------MSGDSTRA--GGPTRRRLIDVAIELFKRYSVAGTSL
TH_2336|M.thermoresistible__bu VSGVGKPISREAALLTSRASAG--TGPTRQRLIEVAIELFKQHSVAGTSL
MSMEG_6537|M.smegmatis_MC2_155 --------------MDTSTAN---AAATRVRLVDAAVRLITRHGFAGTSL
Mvan_0170|M.vanbaalenii_PYR-1 --------------MTTASSAQMPPQSARQRVLDVALALFTRHGYAGTSL
MMAR_4699|M.marinum_M -------MSSQ----SRNQFRVITRSAAQVRILDATLGLIAEHGVGGTSL
MAV_0959|M.avium_104 -------MGTARQAVSDEQFWLVEHSPARTRVLDAALDLFAANGVSGTSL
MAB_2677c|M.abscessus_ATCC_199 -----------------MLSDAAVAPGTRERIQTVARDLFAERGLRNTSL
MUL_0293|M.ulcerans_Agy99 -----------------MVTKPRSD--TRRRIQEVARELFLRQGVRGTSL
Mb0310|M.bovis_AF2122/97 -------------MGVPAKKKQQQGERSRESILDATERLMATKGYAATSI
Rv0302|M.tuberculosis_H37Rv -------------MGVPAKKKQQQGERSRESILDATERLMATKGYAATSI
MLBr_00949|M.leprae_Br4923 ------------MTTSARTHRWAKTGAIQRRILDAAIEVFATRSFTTATM
: : .: :: . :::
Mflv_0973|M.gilvum_PYR-GCK QMISDELGLTKSAIYHHFRTRDELLTAVMEP-LIAEVAEIVDAAEEQRTP
TH_2336|M.thermoresistible__bu QMISDALGLTKSAIYHHFRTRDELLTAVMEP-LISEVAEIVSAAEARRGA
MSMEG_6537|M.smegmatis_MC2_155 QMIADELGFTKAAIYYHFRTREQLLGAVVEP-FLSELQTVIDDAERLRGV
Mvan_0170|M.vanbaalenii_PYR-1 QMIADEMGVTKGSLYYHFRAREDLLRALVGP-LIEQLRAIVEHAEAQRSP
MMAR_4699|M.marinum_M QMIADAVGVTKAAVYHQFKTKEQIVIALTER-ELGGLEEALEAAEAHDHP
MAV_0959|M.avium_104 QMIADAVGITKAAVYHQFRTKEQIVIAVTER-ELGRLVPALEEAEAHDDG
MAB_2677c|M.abscessus_ATCC_199 QDIASRLKITKPALYYHFSSRDELVRSIVQP-MVDDLQTFLATNN---AG
MUL_0293|M.ulcerans_Agy99 QDIADRLGITKPALYYHFASREDLVRSIVVP-LIEEGERFVAERERLADG
Mb0310|M.bovis_AF2122/97 SDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPV
Rv0302|M.tuberculosis_H37Rv SDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPV
MLBr_00949|M.leprae_Br4923 TDAMTGSGAIIGSIYHHFGGKRKLFLAIFEQ------------MGRQRRP
::* :* : :. ::
Mflv_0973|M.gilvum_PYR-GCK HARADHMLVGYASIAARHRTLIPLLS-------GDPGVVALLRTRSEWGD
TH_2336|M.thermoresistible__bu RTRADHFLRGYAALAAAHREVISLLT-------GDPGVVALLRTRPDWAE
MSMEG_6537|M.smegmatis_MC2_155 HARADHMVRGYAGLAVRNRALVSVLA-------GDPSVNEALKTRPEWAA
Mvan_0170|M.vanbaalenii_PYR-1 SVRAEHVLTGYARLAAANRALVAVTS-------GDPSVVEVIHADPDWAD
MMAR_4699|M.marinum_M SQARELLLDRVIELAVERRGAASTLQ-------FDPVIVRLLAEHQPFQR
MAV_0959|M.avium_104 PQARDALLVRVIEMAVRDRRLVRTLQ-------FDPVVVRLLAEHEPFQR
MAB_2677c|M.abscessus_ATCC_199 DRR--QLLEDYFDVLWTHRVVLGIIV-------RDLAALGQLELGEWMMG
MUL_0293|M.ulcerans_Agy99 NVR--GLLEGYFDFHYRHRQDLMLVV-------VELTLLSDLGLIDTVLA
Mb0310|M.bovis_AF2122/97 EQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPVVAAVVRRVRNTAI
Rv0302|M.tuberculosis_H37Rv EQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAI
MLBr_00949|M.leprae_Br4923 PHRRGDATSGPIRPSG------------------DRSAAGIRSPRTGPTS
:
Mflv_0973|M.gilvum_PYR-GCK LVRR---QLALFSEVEPGLGGQVKAALAMSGIASAAGVDYGG-DVDDDTL
TH_2336|M.thermoresistible__bu VVQR---QMALLGDVQPGPGGRVKAAVVMAGIAAAAGVDYG--DLDEAAL
MSMEG_6537|M.smegmatis_MC2_155 LIDR---QMRLLTDVAPGPAGRVKAMMVFSGMSAAAGPASD--DIPVEEL
Mvan_0170|M.vanbaalenii_PYR-1 LIDR---QIGLLAAVQPGLAGRVRATIVMAGIAATAAPGVV--EADEAEL
MMAR_4699|M.marinum_M FIER---LYGVLIG-DAGQDTRVLAAMLSGAIAVGVLHPLVA-DVDDATL
MAV_0959|M.avium_104 FMDR---LYRVLLS-DAGLDGRIEAAMFSGALSTAVMHPLVV-DIDDETL
MAB_2677c|M.abscessus_ATCC_199 WRRR---LIVLLAGGKPSAAQMIQATVALGGLSDCTIEYAD---RPHRQV
MUL_0293|M.ulcerans_Agy99 RRER---LGRLVFGAAPTLGQATRAVLAFGGLQDCCMQFPD---EPYAQL
Mb0310|M.bovis_AF2122/97 ARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTTD
Rv0302|M.tuberculosis_H37Rv ARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTTD
MLBr_00949|M.leprae_Br4923 RRCG-------KTGTRPGCCRPETHLQASRSPVATA--------------
. .
Mflv_0973|M.gilvum_PYR-GCK RDQLIAAGRRALGLRNSRTGAVTARR
TH_2336|M.thermoresistible__bu RDELLAAGRRTLGLR-----APHARG
MSMEG_6537|M.smegmatis_MC2_155 YAHLVDTSRRALGLR-----APREKA
Mvan_0170|M.vanbaalenii_PYR-1 CRQLIDAGRRTLGLR-----APRA--
MMAR_4699|M.marinum_M RTQLRRITSRLMDTGE----G-----
MAV_0959|M.avium_104 LDRVTDLSRRLLGLPR----KPVE--
MAB_2677c|M.abscessus_ATCC_199 KKTAVAAAIAALES------------
MUL_0293|M.ulcerans_Agy99 RQYSVEAALAALGV------------
Mb0310|M.bovis_AF2122/97 VERMYRRLRQALEALIPVLLEET---
Rv0302|M.tuberculosis_H37Rv VERMYRRLRQALEALIPVLLEET---
MLBr_00949|M.leprae_Br4923 --------------------------