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VEFRRSLAALNNGEFHGVALVGDGGVGKSTLARMLAKTVESAGRTVRFALGTQTGWAVPLGAFSRAVSLG VGHEPAIMLAAAHNTLGQDKNLVVVVDEAQLLDPLSATLVNQLAAGRSARLIVTIRSGEPVLDAVTALLK ERLLLTVHVDPFTREQTELLAGAVLGGPVDTRLVDELFERSAGNLLLLRGFLTAGVESGALVHTEQGWQL QGPLRGDRELHDALEYRLQSLSSEEREVVEVLATAELLEWEILRDICDADAMASLERRGLIQLVTDGSHT LVQLNHPMLGEAATRHAGVVRSRQLNGILAKTLRKHLRAAGRRSQISDPRGRIQLAQFIMRSDLEPDLDV VIKAAADAMAMSNVVLGEQLATFAVDRGGGLAAALVLAEAVSWQGRGEEADSILLGADVDDADEWLIARW GCLRAANLAWGCGDAEGATRVLAEVKQRLATEGSLQLIDALDVSIGFFRGDIARTIELGPRLCEPDVVPM ATVWAAVATCGALTAVGRFSEVGRIAAAGVRATAQCRAGAQRFAIGLAEVMAATAAGDYPAAERIHKRYA ALATGLPAAEAMVDAMLGVLQLTRGELQEACATLDRSISQLSQGFPLPWQLVVGALQAQAEGARGDSAAA AVALRRVEEAYGPHVAVFLPELELARAWERAAAGDTAGAQTQAMQAAQTARKAGMHLVEMRARHAALRFG DRAQAARVDELASILNSPSAQAVAGHARGLAQHDGDLLDAAAHRFADLGALAFAADAAAQAASEHARRGD RRKEVESSTWAHALAGQCGSRTPALDAAARPLPFSGRERQIVNLVAAGLSNREIADRLVISVRTVEGHLY RLFTKLGINNRDQLIQLIRRDAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2364 | - | - | 100% (863) | TPR repeat-containing protein |
| M. avium 104 | MAV_2362 | - | 0.0 | 75.35% (860) | TPR repeat-containing protein |
| M. avium 104 | MAV_0578 | - | 6e-95 | 31.03% (867) | transcriptional regulator, LuxR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1236c | - | 7e-70 | 33.80% (568) | hypothetical protein Mb1236c |
| M. gilvum PYR-GCK | Mflv_4479 | - | 1e-128 | 34.83% (844) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv1204c | - | 7e-70 | 33.80% (568) | hypothetical protein Rv1204c |
| M. leprae Br4923 | MLBr_01753 | - | 4e-12 | 22.89% (922) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3907c | - | 1e-135 | 35.28% (873) | LuxR transcriptional regulator |
| M. marinum M | MMAR_4234 | - | 2e-65 | 28.59% (752) | hypothetical protein MMAR_4234 |
| M. smegmatis MC2 155 | MSMEG_2120 | - | 0.0 | 49.30% (858) | TPR repeat-containing protein |
| M. thermoresistible (build 8) | TH_4663 | - | 3e-82 | 32.97% (646) | PUTATIVE putative regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_0955 | - | 2e-66 | 28.72% (752) | hypothetical protein MUL_0955 |
| M. vanbaalenii PYR-1 | Mvan_0243 | - | 0.0 | 52.50% (861) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2120|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0243|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_4234|M.marinum_M --------------------------------------------------
MUL_0955|M.ulcerans_Agy99 --------------------------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK --------------------------------------------------
TH_4663|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MSMEG_2120|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0243|M.vanbaalenii_PYR-1 -------------------------------------------MTEKWTE
MAV_2364|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 -------------------MTTTTGTIDGRGQAPRLSPAKVHPDLHSYPM
MMAR_4234|M.marinum_M --------------------------------------------------
MUL_0955|M.ulcerans_Agy99 --------------------------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK --------------------------------------------------
TH_4663|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
MSMEG_2120|M.smegmatis_MC2_155 MSGWPFVGRDDELREAAEALRDSS--RGVVLAGPSGVGKTALARALAGQL
Mvan_0243|M.vanbaalenii_PYR-1 LPDWPLVGRARELGRAIDALRPGSGFRGVVFVGEPGSGKTTLARAIAATL
MAV_2364|M.avium_104 ----------MEFRRSLAALNNGE-FHGVALVGDGGVGKSTLARMLAKTV
MAB_3907c|M.abscessus_ATCC_199 ARSWQLLDRQTEFGAVRSAMADDS-TCGAVLVGAAGVGKTTLARAVTKSL
MMAR_4234|M.marinum_M MPIRWNVPQHAAALEQLDVALSDLARPGAVILGPDGVGKSTLARLAAEHF
MUL_0955|M.ulcerans_Agy99 -------------MEQLDVALSDLARPGAVILGPDGVGKSTLARLAAEHF
Mb1236c|M.bovis_AF2122/97 ----------MRVWKHVEAAVDSPDRCGVVLVGPHGVGKTLLAQLAAEQV
Rv1204c|M.tuberculosis_H37Rv ----------MRVWKHVEAAVDSPDRCGVVLVGPHGVGKTLLAQLAAEQV
Mflv_4479|M.gilvum_PYR-GCK ------MTAGLGLARTQVESAIVASRLRAVLVGAAGVGKTSMARKLARDY
TH_4663|M.thermoresistible__bu -----------------------------VLVGPAGAGKTELARTVLQHR
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
. . . .: :
MSMEG_2120|M.smegmatis_MC2_155 ETEGY----TIRYVLGTETGQAVPFGAFHHTLELS----DAHEPTVMLAA
Mvan_0243|M.vanbaalenii_PYR-1 RSEGV----TTRFVLGTDTGQAVPLGAFHRTLSIE----DPHEPAVMLAA
MAV_2364|M.avium_104 ESAGR----TVRFALGTQTGWAVPLGAFSRAVSLG----VGHEPAIMLAA
MAB_3907c|M.abscessus_ATCC_199 DAD-------VRWVACTESSRSIPLGVFAHWIQAS----GSRDPTALIAA
MMAR_4234|M.marinum_M AQRHP--ATVIRWVTGTPTERTVPFGAFSHLVEI----AELGKPAALLRA
MUL_0955|M.ulcerans_Agy99 AQRHP--ATVIRWVTGTPTERAVPLGAFSHLVEI----AELGKPAALLRA
Mb1236c|M.bovis_AF2122/97 MSEDGR-SGRARWVVGTAPGRAIPFGAFRHLISLPASGADIGRPAALLRA
Rv1204c|M.tuberculosis_H37Rv MSEDGR-SGRARWVVGTAPGRAIPFGAFRHLISLPASGADIGRPAALLRA
Mflv_4479|M.gilvum_PYR-GCK ARKHP--RLTSHWVSATASARDIPFAAFSHLIDV----SGGEEPTTLLRA
TH_4663|M.thermoresistible__bu RREQP--HTVLHWVAGTASASRIPFGAFSHLVET----GGGGEPATVLRT
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSH-LLRDLARPVRVMQL
:* .: : *. ::
MSMEG_2120|M.smegmatis_MC2_155 AHHTLSA-----------------------------DPNVLIVVDDAQYL
Mvan_0243|M.vanbaalenii_PYR-1 AHRALAR-----------------------------EHNLVLAIDDAHLL
MAV_2364|M.avium_104 AHNTLGQ-----------------------------DKNLVVVVDEAQLL
MAB_3907c|M.abscessus_ATCC_199 ARESIVS-----------------------------TANPIIGIDDAHLL
MMAR_4234|M.marinum_M ARASLGRKV--------------------------RQGELLLIVDDAHDL
MUL_0955|M.ulcerans_Agy99 ARASLGRKV--------------------------RQGELLLIVDDAHDL
Mb1236c|M.bovis_AF2122/97 ARSSLTG----------------------------DAGDLLLVVDDAHNL
Rv1204c|M.tuberculosis_H37Rv ARSSLTG----------------------------DAGDLLLVVDDAHNL
Mflv_4479|M.gilvum_PYR-GCK ARESLR-----------------------------SAHGLLLVVDDAHHL
TH_4663|M.thermoresistible__bu ARESLCGPVLRD----------------------RTRTGLLLIVDDAHHL
MLBr_01753|M.leprae_Br4923 CHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLL
.: : : : : *
MSMEG_2120|M.smegmatis_MC2_155 DPLS------ALLVQQLAVHGSIKLIVTMRSGATTSDAVTALWKEHLLVR
Mvan_0243|M.vanbaalenii_PYR-1 DPLS------ALLVQQAATSDTARLIVTIRSGEVVPDAVTALWKEQLLMR
MAV_2364|M.avium_104 DPLS------ATLVNQLAAGRSARLIVTIRSGEPVLDAVTALLKERLLLT
MAB_3907c|M.abscessus_ATCC_199 DDLS------ATLLHQIAVDHVGHVVATVRSGEPVPDAVTALWKDNYLQR
MMAR_4234|M.marinum_M DILS------ATLVYQLALAGAARMIVTARAEVAP-EAIAALWTDNLLDR
MUL_0955|M.ulcerans_Agy99 DILS------ATLVYQLALAGAARMIVTARAEVAP-EAIAALCTDNLLDR
Mb1236c|M.bovis_AF2122/97 DPLS------ATLVYQLARAGAARLVVTVASEAEPPDAIAALWSDDLLTR
Rv1204c|M.tuberculosis_H37Rv DPLS------ATLVYQLARAGAARLVVTVASEAEPPDAIAALWSDDLLTR
Mflv_4479|M.gilvum_PYR-GCK DTLS------ATLVHQLAVTDNAHIMLTVREGEPVPDAVTALWKDSILSR
TH_4663|M.thermoresistible__bu DTLS------ATLVHQVAVSTPASLLLTVRDGEPVPDAITALWKDDLLAR
MLBr_01753|M.leprae_Br4923 TLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDN
:. : * * . . :: : *
MSMEG_2120|M.smegmatis_MC2_155 LDVEPFSRAQTAEVASTVLGGEVDEHAVAELHRYSSGSPMFLRGVLTAAM
Mvan_0243|M.vanbaalenii_PYR-1 VDLNAFDRTQTQELVDAVLDGEVDSSVVDRLHDLAGGSPLVLRGLIGAAR
MAV_2364|M.avium_104 VHVDPFTREQTELLAGAVLGGPVDTRLVDELFERSAGNLLLLRGFLTAGV
MAB_3907c|M.abscessus_ATCC_199 FELDPLTQRQSIALVEKVLGGPLEGLSADVMWRSSRGNPLFLRHLVEGSM
MMAR_4234|M.marinum_M IDVAPPD-------------------------------------------
MUL_0955|M.ulcerans_Agy99 IDVAPPD-------------------------------------------
Mb1236c|M.bovis_AF2122/97 VAIEPLDRAQTAAFVESALDATLDVADADELFRRSLGNPLYLRHLID---
Rv1204c|M.tuberculosis_H37Rv VAIEPLDRAQTAAFVESALDATLDVADADELFRRSLGNPLYLRHLID---
Mflv_4479|M.gilvum_PYR-GCK HDIAPFDRRESGLLLEQILGGTVEDVSTVRMFEISQGNPLYLRHLVDAAL
TH_4663|M.thermoresistible__bu IDIEPFSQAECERLLADALGGRVESASAERLYAISEGNPLYLRHLVTGTV
MLBr_01753|M.leprae_Br4923 LRRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPSLTILATSREPIGV
MSMEG_2120|M.smegmatis_MC2_155 GDGVLVQAHGRWRLRGNLRPSPDLYELIASRVETLSAEELDVAEVVATAD
Mvan_0243|M.vanbaalenii_PYR-1 EDGVLVRQGGRWRLHGRLRVGTDVHELVQTQLAGLTEGEFEVVEIVSAAE
MAV_2364|M.avium_104 ESGALVHTEQGWQLQGPLRGDRELHDALEYRLQSLSSEEREVVEVLATAE
MAB_3907c|M.abscessus_ATCC_199 QAGSLTEVNGVWQLRGDAVVPSGLDTLIGDRLEHVDDTVFSALKVLSMCE
MMAR_4234|M.marinum_M ---------------GKTKQS--EPADVDEFIAELPAPARAVLDYLTVEE
MUL_0955|M.ulcerans_Agy99 ---------------GQTKQS--EPADVDEFIAELPAPARAVLDYLTVEE
Mb1236c|M.bovis_AF2122/97 -GGGLEHVDGRWRCRDEDRRP--LSGVIDEYLCALPEPARAVVDYLAIAE
Rv1204c|M.tuberculosis_H37Rv -GGGLEHVDGRWRCRDEDRRP--LSGVIDEYLCALPEPARAVVDYLAIAE
Mflv_4479|M.gilvum_PYR-GCK GTGSLRQVEGVWQLRGEMTLSPQLTTLIDAHLTNLPEPVRSVLEFLAIDD
TH_4663|M.thermoresistible__bu ASGALREVEGIWQLRGEVALTPQLSTLIDQHLSALPDQIRTVLAYLAIEE
MLBr_01753|M.leprae_Br4923 AGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLD
: . . :
MSMEG_2120|M.smegmatis_MC2_155 MLDWHVLLAICG---PDAVARAE-----------RRGAIQVTSAGSHAVV
Mvan_0243|M.vanbaalenii_PYR-1 VLDWNVLRALCD---AEAIARTE-----------HRGVIEFVDDGSHTLV
MAV_2364|M.avium_104 LLEWEILRDICD---ADAMASLE-----------RRGLIQLVTDGSHTLV
MAB_3907c|M.abscessus_ATCC_199 PLDIDTLCEIAS---DEAVDAAE-----------IADLIRVERDGVRTVV
MMAR_4234|M.marinum_M PLSLADLTVLAGEGAVQQAVELG-----------AAETRVRGEPDEPAVV
MUL_0955|M.ulcerans_Agy99 PLSLADLTVLAGEGAVQQAVELG-----------AAETRVRGEPDEPAVV
Mb1236c|M.bovis_AF2122/97 PLARTDLVALVGGEQLDTLGQAE-----------AAGAVRVGPDSDTSEI
Rv1204c|M.tuberculosis_H37Rv PLARTDLVALVGGEQLDTLGQAE-----------AAGAVRVGPDSDTSEI
Mflv_4479|M.gilvum_PYR-GCK PLSVDDLAALTG---IDAVDAAE-----------TCGVVTITDRAGALYA
TH_4663|M.thermoresistible__bu PLTVADLSDLVS---PEAVEAAE-----------AAGAVTVDERGADLIV
MLBr_01753|M.leprae_Br4923 GMPLAIELAAARIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASM
: .
MSMEG_2120|M.smegmatis_MC2_155 QPGHPIIGEVVRSRCPVSRTRQ----------------------------
Mvan_0243|M.vanbaalenii_PYR-1 RAGHPILGEVVRQRGGVARTRQ----------------------------
MAV_2364|M.avium_104 QLNHPMLGEAATRHAGVVRSRQ----------------------------
MAB_3907c|M.abscessus_ATCC_199 RFSHPMFGEAVRRRVGTASGRR----------------------------
MMAR_4234|M.marinum_M YTAHPLFAKRARVALGDDGARQ----------------------------
MUL_0955|M.ulcerans_Agy99 YTAHPLFAKRARVALGDDGARQ----------------------------
Mb1236c|M.bovis_AF2122/97 FVGHPLYADRARAVLTAEHAHA----------------------------
Rv1204c|M.tuberculosis_H37Rv FVGHPLYADRARAVLTAEHAHA----------------------------
Mflv_4479|M.gilvum_PYR-GCK HPFHPIYTERVRSSLGLLAMRR----------------------------
TH_4663|M.thermoresistible__bu HPAHPLYTETVRAGLGRLTRRS----------------------------
MLBr_01753|M.leprae_Br4923 DWSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRLTM
:.: .
MSMEG_2120|M.smegmatis_MC2_155 ---------------INTLVAEHLS-AQLRVATDAS---AVDVRTRIQLA
Mvan_0243|M.vanbaalenii_PYR-1 ---------------LNTMLAQSIS-DFLGTDATHPYSVGADVRSRIQLA
MAV_2364|M.avium_104 ---------------LNGILAKTLR-KHLRAAGRRS--QISDPRGRIQLA
MAB_3907c|M.abscessus_ATCC_199 ---------------LRGKLVRVLRDRDLGTAS-----------NRIRLA
MMAR_4234|M.marinum_M ---------------RRTELVTLLSQHPNEHLS-----------DRLRLA
MUL_0955|M.ulcerans_Agy99 ---------------RRTELVTLLSQHPNEHLS-----------DRLRLA
Mb1236c|M.bovis_AF2122/97 ---------------LRVSLVAQLAKHPSDHVS-----------DQLRLS
Rv1204c|M.tuberculosis_H37Rv ---------------LRVSLVAQLAKHPSDHVS-----------DQLRLS
Mflv_4479|M.gilvum_PYR-GCK ---------------LRKLLAGRMSVRAPGNLS-----------TRLRMA
TH_4663|M.thermoresistible__bu ---------------LRTALVARWSRRPPDNVS-----------DRLRLA
MLBr_01753|M.leprae_Br4923 LIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYM
. : : :
MSMEG_2120|M.smegmatis_MC2_155 RFMTRAESPPD---TDLVTEAAASAVTMSDLVLGEQLARFAVEHGAGVNA
Mvan_0243|M.vanbaalenii_PYR-1 RFMTCSDAEPD---LELITAAAADAVTMSNLVLAEQLARFAFDRGGGLPS
MAV_2364|M.avium_104 QFIMRSDLEPD---LDVVIKAAADAMAMSNVVLGEQLATFAVDRGGGLAA
MAB_3907c|M.abscessus_ATCC_199 RLSIDCDEPVD---VDLLVTAAKDAVYLSNLPLGEELARAAVDGGGGLQA
MMAR_4234|M.marinum_M SLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAALDRSGGLQA
MUL_0955|M.ulcerans_Agy99 SLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAALDRSGGLQA
Mb1236c|M.bovis_AF2122/97 SLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAALDRSDALAA
Rv1204c|M.tuberculosis_H37Rv SLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAALDRSDALAA
Mflv_4479|M.gilvum_PYR-GCK ALAMGTDEPPS---ADELVGLSWEAMRLGDLALGERLARAALDQADGLAA
TH_4663|M.thermoresistible__bu ALAVNSQTPPP---ATDLIATSWEAMQLGDLLLGEQLARGALGQSDTLAA
MLBr_01753|M.leprae_Br4923 ALGALLDTPGD---IDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQL
: :.:: . : : . :
MSMEG_2120|M.smegmatis_MC2_155 ALVLADAISWQGRGDEADALLARYPPDG------EDDLTVTRWGCQRAAN
Mvan_0243|M.vanbaalenii_PYR-1 AIALADAISWQGRGQEAEAILAAFDPDG------ADALMTVRWGCLRGAN
MAV_2364|M.avium_104 ALVLAEAVSWQGRGEEADSILLGADVDD------ADEWLIARWGCLRAAN
MAB_3907c|M.abscessus_ATCC_199 AAMLSRSLLWQGRPEQAEEILAAFDPDD------LDELSLVLWGIPRISI
MMAR_4234|M.marinum_M RLVLGQALAWRGRGREAGQVLTAVDPGQ------LSEAELMAWAVPQAAN
MUL_0955|M.ulcerans_Agy99 RLVLGQALAWRGRGREAGQVLTAVDPGQ------LSEAELMAWAVPQAAN
Mb1236c|M.bovis_AF2122/97 RLPLAYALGWQGRGREADAVLAAVNPAE------LTETELMAWAIPRAAN
Rv1204c|M.tuberculosis_H37Rv RLPLAYALGWQGRGREADAVLAAVNPAE------LTETELMAWAIPRAAN
Mflv_4479|M.gilvum_PYR-GCK RLPLAHSLSWQGRGRDADDVLNPVDPDT------LTQWDLMAWTLPKAAN
TH_4663|M.thermoresistible__bu RLPLAHALAWQGRGREADDVLAAVDPDR------LTEFDIMAWTLPKAAN
MLBr_01753|M.leprae_Br4923 ASSLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVML
* :*: :. : :
MSMEG_2120|M.smegmatis_MC2_155 LFFVCGRPEPAWEVLAKTRDAVGSGKLTGLVTAMEVAFTYF------SAD
Mvan_0243|M.vanbaalenii_PYR-1 LFFGCGHSDGAWAALATVRERVASEDLLSLVTAMEVSLAFF------SGD
MAV_2364|M.avium_104 LAWGCGDAEGATRVLAEVKQRLATEGSLQLIDALDVSIGFF------RGD
MAB_3907c|M.abscessus_ATCC_199 AFWSMGENERAHELLALLHERVRHHILKPVVDATDAAIALH------ENR
MMAR_4234|M.marinum_M QFWMLGEPERATAFLQTTRNRVTDLTARTTLDALTATFAMN------SGN
MUL_0955|M.ulcerans_Agy99 QFWMLGEPERATAFLQTTRNRVTDLTARTTLDALTATFAMN------SGN
Mb1236c|M.bovis_AF2122/97 RFWMLNEPERATAFLQTTRSRVTEPTARSTLDALAATFAMN------SGN
Rv1204c|M.tuberculosis_H37Rv RFWMLNEPERATAFLQTTRSRVTEPTARSTLDALAATFAMN------SGN
Mflv_4479|M.gilvum_PYR-GCK RFWMLSESEEAVEYLRQMRARITERGALHTIDALAATFAMN------AGD
TH_4663|M.thermoresistible__bu QFWMLSESAEAIALLDRMRTRLHQPAAVTAFDALAATFAMN------AGQ
MLBr_01753|M.leprae_Br4923 HAILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTE
. . : : : . ::
MSMEG_2120|M.smegmatis_MC2_155 MAGAAAAGSAALATEMMP-AATVWVALATAGALAKSGRFSEVAAVVRTGE
Mvan_0243|M.vanbaalenii_PYR-1 VPVAVRLGQAALATERMP-MATVWAAMATAGALSLSGRLDEVRPIARQGL
MAV_2364|M.avium_104 IARTIELGPRLCEPDVVP-MATVWAAVATCGALTAVGRFSEVGRIAAAGV
MAB_3907c|M.abscessus_ATCC_199 FDEGLARAHAVLSDPVAPKQAVEFAAFGVGLTLPVAGRGHEFEPIAQRCR
MMAR_4234|M.marinum_M VPRAITLATEVLAEPSADDTAIAWAASAAALASARMGRFADVPQLAQRAS
MUL_0955|M.ulcerans_Agy99 VPRAITLATEVLAEPSADDTAIAWAASAAALASARMGRFADVPQLAQRAS
Mb1236c|M.bovis_AF2122/97 LPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGRFGDVDRLAERAS
Rv1204c|M.tuberculosis_H37Rv LPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGRFGDVDRLAERAS
Mflv_4479|M.gilvum_PYR-GCK PAEAVTVAKGILAADDAQDLAVAWASAAATLSSARMGRFAEVDGLAQRGL
TH_4663|M.thermoresistible__bu PRTALELAGRVLQTPESQDLAVAWAAATATLSSARMARFDEVETHAARGL
MLBr_01753|M.leprae_Br4923 VARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAAD
: . . .
MSMEG_2120|M.smegmatis_MC2_155 HAASRCESGPHRYSLPLAEVLAGTLAGEFDDAQRACDRYAAASSD-IPQA
Mvan_0243|M.vanbaalenii_PYR-1 QAARYCESGPQHYTIGLAEVLAYTASGDMDAADHACERYSAMTCG-VPQA
MAV_2364|M.avium_104 RATAQCRAGAQRFAIGLAEVMAATAAGDYPAAERIHKRYAALATG-LPAA
MAB_3907c|M.abscessus_ATCC_199 DDKKRTTDGLIAAMVRYCDVLALTYTGQLDLAEERVAEYTKFSSAGQFLA
MMAR_4234|M.marinum_M EAEH---PGLLRFTVGLAQITTLLMAGEVAQAQELAQRFTDFAEL-QQPG
MUL_0955|M.ulcerans_Agy99 EAEH---PGLLRFTVGLAQITTLLMAGEVAQAQELAQRFTDFAEL-QQPG
Mb1236c|M.bovis_AF2122/97 AAEH---PGLLRFTVGLAQITSLLLAGDVAPAQELAKRFTDFA-------
Rv1204c|M.tuberculosis_H37Rv AAEH---PGLLRFTVGLAQITSLLLAGDVAPAQELAKRFTDFA-------
Mflv_4479|M.gilvum_PYR-GCK DAAH---PGLLRFTLGLGQTLALIMNADVASAEHLARHYLSFSEF-QQPG
TH_4663|M.thermoresistible__bu AAQH---PGLLRFTIGLGQITRLILAGXLTRADFLAHHYLSFCEF-QQPG
MLBr_01753|M.leprae_Br4923 DLAQEIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTV
. * .
MSMEG_2120|M.smegmatis_MC2_155 DVMVTALAGRMKLARGQLEDACEQLQAAVWSMAAKLPPGWPMLVASWLAQ
Mvan_0243|M.vanbaalenii_PYR-1 EAIVNALVGRVNFARGLLAAACDALSTSLWTMSESLPSGWVMLVAAWLAQ
MAV_2364|M.avium_104 EAMVDAMLGVLQLTRGELQEACATLDRSISQLSQGFPLPWQLVVGALQAQ
MAB_3907c|M.abscessus_ATCC_199 WAIARIMAGVVATQRGLFREAIEAFEQALAAQRADRPLPWQLPARLLLAR
MMAR_4234|M.marinum_M RAIGEVLLAHVLIVKGEFGAAAAMLEPAAAELERTG-YSWGPLSLMLLAT
MUL_0955|M.ulcerans_Agy99 RAIGEVLLAHVLIVKGEFGTAAAMVEPAAAELERTG-YSWGPLSLMLLAT
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK RAIGEVLLGHTLLASGRFGDAVTLLRQAAAALTYTG-YSWGPLALTGLAQ
TH_4663|M.thermoresistible__bu RAIGEVLLAHILIARGDLPTATTLLRQAAAALSSTG-YSWGPLALMQLTQ
MLBr_01753|M.leprae_Br4923 TRTFGLYVQTRALVHRDVSAALVTAG-LVVEAAAELSGVYQGIGYAAMVF
MSMEG_2120|M.smegmatis_MC2_155 AEGARGNAEAAAVALTKAEAEVGPQVEVFAPELELARAWRAAA-------
Mvan_0243|M.vanbaalenii_PYR-1 AEAARGNADGAAAALARAEDANGPQVAVFVPELELARSWHRAC-------
MAV_2364|M.avium_104 AEGARGDSAAAAVALRRVEEAYGPHVAVFLPELELARAWERAA-------
MAB_3907c|M.abscessus_ATCC_199 AYAALGRAVDGERVLDEAREHSGPHVAIHMPQMMLAKAWLVAA-------
MMAR_4234|M.marinum_M AIAQQGNIAETAKALRRAETRHGTKSALFAPELSLARAWAKAT-------
MUL_0955|M.ulcerans_Agy99 AIAQQGNIAETAKALRRAETRHGTKSALFAPELSLARAWAKAT-------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK ALGQQGRAADASAVLTRAEASHGMRSALYAPDLALARAWTLAA-------
TH_4663|M.thermoresistible__bu VLGARGDADGASEALRRAEHSHGTRSELYAPELALX-XXXWRG-------
MLBr_01753|M.leprae_Br4923 AALAMGDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVAR
MSMEG_2120|M.smegmatis_MC2_155 ------AGETSRAQHHAVLAAQNAHAAGMTAVELTALHTSTRFGDRTVDA
Mvan_0243|M.vanbaalenii_PYR-1 ------VGQTTTARDHALRAAQTARVKGMWAVEMCALHTAVRFGDRSQSA
MAV_2364|M.avium_104 ------AGDTAGAQTQAMQAAQTARKAGMHLVEMRARHAALRFGDRAQAA
MAB_3907c|M.abscessus_ATCC_199 ------RGSDRGAVDAARRAADAAHSAGQYALEAEALHHAARFGDRTVGR
MMAR_4234|M.marinum_M ------VRDQAGALFDTREAARAAERGKQSAVALCVWHDAVRLGDTRALA
MUL_0955|M.ulcerans_Agy99 ------VRDQAGALFDTREAARAAERGKQSAVALCVWHDAVRLGDTRALA
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK ------ARDLRGAVASARDAVHAAVQSGQDAVALRALQDCARLGDTHGLA
TH_4663|M.thermoresistible__bu ------LRDESGHLAAYRITVDDRLP-----ETLADLWD----GSAAEVW
MLBr_01753|M.leprae_Br4923 RLADNSVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQ
MSMEG_2120|M.smegmatis_MC2_155 RIQQLPTELDCPLGEAIALHSSGLAGHDGNRLVTAADRFERIGAMVLAGD
Mvan_0243|M.vanbaalenii_PYR-1 RLRQCAAQLDSPLAEAIAAHGIGLSDHDGDRLDAAADMFDRLGAAAMAAD
MAV_2364|M.avium_104 RVDELASILNSPSAQAVAGHARGLAQHDGDLLDAAAHRFADLGALAFAAD
MAB_3907c|M.abscessus_ATCC_199 RIESLCTRVHGPLTGLYARHALAVAHSDITGLEAVSADFEAAGLLLSAAD
MMAR_4234|M.marinum_M PVTRLAAEIDCKVGNIVVRHARALADNDAGALASVADELAAIGMHAAAAD
MUL_0955|M.ulcerans_Agy99 PVTRLAAEIDCKVGNIVVRHARALANNDAGALASVADELAAIGMHAAAAD
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK TAVRLSDRIGCVTGPLCVAHLRALAAGDGAALDAVSADLETAGLPAAAAD
TH_4663|M.thermoresistible__bu TAIEFS---GTTAHPMITAG----------------CALRSEKKPEAAGP
MLBr_01753|M.leprae_Br4923 ASLGISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAG
MSMEG_2120|M.smegmatis_MC2_155 AAAHASREFGRRGERGNELEASTRAHWLASRCG-AVTPALRCAADPLP--
Mvan_0243|M.vanbaalenii_PYR-1 ASAHAAREHARAGARVKELEATTRAHWLAGRNC-VRTPAVTAIEDPLP--
MAV_2364|M.avium_104 AAAQAASEHARRGDRRKEVESSTWAHALAGQCG-SRTPALDAAARPLP--
MAB_3907c|M.abscessus_ATCC_199 AAAQAVALRMRAGDRGKGSDAAARVLRMADRCGGVVTPAILAAAKPLP--
MMAR_4234|M.marinum_M AAAQAERAGGR---------------------------------------
MUL_0955|M.ulcerans_Agy99 AAAQAERAGGR---------------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK AAAQATFAHQRRGDRAGEVASRSRASRLSQVCGAPATPALEQVLNPMP--
TH_4663|M.thermoresistible__bu LPALTPQRGLHR--PALEALAPTSGRRLPG--------------EPVP--
MLBr_01753|M.leprae_Br4923 YESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGW
MSMEG_2120|M.smegmatis_MC2_155 --LTPREWEIANLVSSGLSNRQVADRLCLSVRTVDGHLYRMFAKLGVADR
Mvan_0243|M.vanbaalenii_PYR-1 --ITDREREIAVLVGESLTNREIAERLGVSVRTIDGHLYRIFAKLSIEDR
MAV_2364|M.avium_104 --FSGRERQIVNLVAAGLSNREIADRLVISVRTVEGHLYRLFTKLGINNR
MAB_3907c|M.abscessus_ATCC_199 --ISSREREIAVLIGEGLSDKDIATRLQLSVRTVEGHIYRARMKLDADDR
MMAR_4234|M.marinum_M --------------------------------------------------
MUL_0955|M.ulcerans_Agy99 --------------------------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK --LTGREREVAVMVSQGLTNKAIAQRLSVSVRTVEGHVYRACMKFGVPDR
TH_4663|M.thermoresistible__bu --LPDGLLDSLFWPVRGVRSTARQRRTARQVETES------------VDT
MLBr_01753|M.leprae_Br4923 ESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSR
MSMEG_2120|M.smegmatis_MC2_155 DQLAKLIRFRPAT----
Mvan_0243|M.vanbaalenii_PYR-1 EQLARLFRIRPAT----
MAV_2364|M.avium_104 DQLIQLIRRDAS-----
MAB_3907c|M.abscessus_ATCC_199 EEFAKIVGSDLKPPEAS
MMAR_4234|M.marinum_M -----------------
MUL_0955|M.ulcerans_Agy99 -----------------
Mb1236c|M.bovis_AF2122/97 -----------------
Rv1204c|M.tuberculosis_H37Rv -----------------
Mflv_4479|M.gilvum_PYR-GCK AALASTVGGMHGREGTA
TH_4663|M.thermoresistible__bu APVSRT-----------
MLBr_01753|M.leprae_Br4923 VQLVQEAARHN------