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VDGSERPVNHHGDHPGFSGLTGQLCAVAFLLTGRETGRLAADLTAVSATDHVLDIGCGPGNACRIAAARG ARVTGVDPSAAMLRVARIVTHGASVTWVRGGAEALPVPDAGATVAWALATVHHWPDVDAGLAEIHRALGP GARFLAVERQTEPDATGISSHGWTGAQAETFAAMCESAGLTTVRVGSGRAGKRRVWTVHATRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4035 | - | - | 100% (203) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_4060 | - | 4e-09 | 37.76% (98) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_2862 | - | 9e-09 | 36.21% (116) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0336c | - | 6e-11 | 30.60% (134) | hypothetical protein Mb0336c |
| M. tuberculosis H37Rv | Rv0329c | - | 1e-12 | 31.34% (134) | hypothetical protein Rv0329c |
| M. leprae Br4923 | MLBr_01723 | - | 9e-09 | 29.91% (107) | hypothetical protein MLBr_01723 |
| M. abscessus ATCC 19977 | MAB_1294c | - | 2e-12 | 40.00% (100) | hypothetical protein MAB_1294c |
| M. marinum M | MMAR_1663 | - | 3e-08 | 29.06% (117) | hypothetical protein MMAR_1663 |
| M. avium 104 | MAV_4426 | - | 1e-08 | 33.91% (115) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_2632 | - | 2e-58 | 54.04% (198) | SAM-dependent methyltransferase |
| M. thermoresistible (build 8) | TH_1968 | - | 7e-09 | 35.58% (104) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | MUL_2765 | - | 2e-08 | 34.39% (157) | methyltransferase (methylase) |
| M. vanbaalenii PYR-1 | Mvan_2319 | - | 4e-70 | 71.35% (178) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4035|M.gilvum_PYR-GCK ----------MDGSERPVNHHGDHPGFSGLTGQLCAVAFLLTGRETGR--
Mvan_2319|M.vanbaalenii_PYR-1 ------------------------------------MLFLLAGRRTAG--
MSMEG_2632|M.smegmatis_MC2_155 ----------MNDSPIVVNHHADHPGFSGVTGAIFGVLFVALGRANAK--
Mb0336c|M.bovis_AF2122/97 ---------MRLTHPARRYLSSQAARPTGAFGRLLGRIWRAETADVNR--
Rv0329c|M.tuberculosis_H37Rv ---------MRLTHPARRYLSSQAARPTGAFGRLLGRIWRAETADVNR--
MLBr_01723|M.leprae_Br4923 MTRSTEISANAVPNPHATAEQVAAARKDSKLAQVLYHDWEAENYDEKWSI
MMAR_1663|M.marinum_M MTRSSEIPADAAPNPHATAEEVEAARHDSKLAQVLYHDWEAENYDEKWSI
TH_1968|M.thermoresistible__bu -----------------------------LSFGAEAAAYERGRPSYPP--
MUL_2765|M.ulcerans_Agy99 -----------MTTVPRRGFNDAVTGIWSLLAPAYDLAILQQWVYRPP--
MAV_4426|M.avium_104 ----------------MRFRNVLFPYVYRFGQPVFDRLFYQRYR------
MAB_1294c|M.abscessus_ATCC_199 ---------------------------------MPDHGRWNHNIHYQR--
Mflv_4035|M.gilvum_PYR-GCK -----------------LAADLTAVSATDHVLDIGCGPGNACRIAAARGA
Mvan_2319|M.vanbaalenii_PYR-1 -----------------LAAALTEVTASDHVVDIGCGPGNGARIAAQRGA
MSMEG_2632|M.smegmatis_MC2_155 -----------------VAIEATQVGPIDHVVDVGCGPGTAARMAARRGA
Mb0336c|M.bovis_AF2122/97 -----------------IAVELLAPGPGERVCEIGFGPGRTLGLLAAAGA
Rv0329c|M.tuberculosis_H37Rv -----------------IAVELLAPGPGERVCEIGFGPGRTLGLLAAAGA
MLBr_01723|M.leprae_Br4923 SYDQRCVDYVRHCFDAIVPDELFTELPYDCALELGCGTGFFLLNLIQSGV
MMAR_1663|M.marinum_M SYDQRCVEYARGRFDAIVPAQVHADLPYERALELGCGTGFFLLNLIQAGV
TH_1968|M.thermoresistible__bu -----------------EAIDWLLPSDARDVLDLGAGTGKLTTRLVERGL
MUL_2765|M.ulcerans_Agy99 ---------------HDEVLAQLRAHKSRRIADIACGTGILSARIERELH
MAV_4426|M.avium_104 --------------------RQAMSHATGRLLMVGLGPGTDLMFLPAAVT
MAB_1294c|M.abscessus_ATCC_199 ------------------EVLRRVPAHATDVLDVGCGIGMLTRELAPLAQ
:. * *
Mflv_4035|M.gilvum_PYR-GCK RVTG--VDPSAAMLRVAR-IVTHG---ASVTWVRGGAEALPVPDAGATVA
Mvan_2319|M.vanbaalenii_PYR-1 RVTG--VDPSRSMLRVAR-AVTRGR--PAITWAEGTAEALPVPDASATVV
MSMEG_2632|M.smegmatis_MC2_155 RVTA--VDPSAEMLRVGR-LVTPSAAGKNITWRPGTAEDVPVDDGTATVV
Mb0336c|M.bovis_AF2122/97 QVSG--VEVSTTMIAIAAHHNAKAIAAGLISLYHGDGVTLPVADHSLDKV
Rv0329c|M.tuberculosis_H37Rv QVSG--VEVSTTMIAIAAHHNAKAIAAGLISLYHGDGVTLPVADHSLDKV
MLBr_01723|M.leprae_Br4923 ARRGSVTDLSPGMVKIATRNGQSLGLD--INGRVADAEGIPYDDNTFDLV
MMAR_1663|M.marinum_M ARRGSVTDLSPGMVKVATRNGQSLGLD--IDGRVADAEGIPYDDDTFDLV
TH_1968|M.thermoresistible__bu NVTA--VDPIPEMLELLSKSLPDTP------ALLGTAEEIPLPDNSVDAV
MUL_2765|M.ulcerans_Agy99 PDEIYGVDMSHGMLDQARAKSDRVR------WLRGPAEQLPFDDGALDAV
MAV_4426|M.avium_104 SVAA--VEPEASFRRMAARLAARQG--VAVDVVAGSGESIPFPDNSFDSV
MAB_1294c|M.abscessus_ATCC_199 RVVG--IDPHEPSLRIARAETSASN----VEYVRGSFLEHPFPAESFDLI
: . *
Mflv_4035|M.gilvum_PYR-GCK WALATVHHWPDVDAGLAEIHRALGPGARFLAVERQTEP-------DATGI
Mvan_2319|M.vanbaalenii_PYR-1 WALATVHHWRDVGAGLSEIHRVLVPGGRLLAVERQVAP-------DATGF
MSMEG_2632|M.smegmatis_MC2_155 WALATVHHWQDVVRALQQANRVLAPGGRLLAIERQVAR-------GATGF
Mb0336c|M.bovis_AF2122/97 LGVHNFYFSPDPRASLCDIARALRPGGRLVLTSISDDQ------PLAARF
Rv0329c|M.tuberculosis_H37Rv LGVHNFYFWPDPRASLCDIARALRPGGRLVLTSISDDQ------PLAARF
MLBr_01723|M.leprae_Br4923 VGHAVLHHIPDVELSLREVLRVLKPGGRFVFAGEPTDVGN----RYARVF
MMAR_1663|M.marinum_M VGHAVLHHIPDVELSLREVMRVLKPGGRFVFAGEPTTVGN----EYARTL
TH_1968|M.thermoresistible__bu L-VAQAWHWFDVDRAVREVARVLRPGGRLGLVWNTRDERMGWVKELGRII
MUL_2765|M.ulcerans_Agy99 VTITAFHFFDQP-AALREFHRVLAPGGLVAVSSLSARQP------LLQLP
MAV_4426|M.avium_104 HIGLVLCSVRDVGATLAEIRRVLVPGGRLVVLEHVRGDGLTG---RLQDL
MAB_1294c|M.abscessus_ATCC_199 AAVAALHH-MDIEQGLRRMSDLLKPGGRIVIVGFAANRSVTDLWYDGLGF
: : * **. .
Mflv_4035|M.gilvum_PYR-GCK SSHGWTGAQAETFAAMCESAGLTTVRVGSGRAGKRRVWTVHATRP-----
Mvan_2319|M.vanbaalenii_PYR-1 ASHGWTGQQAETFAALCVTAGLADAKVNADRAGRREVWTVHAVRP-----
MSMEG_2632|M.smegmatis_MC2_155 ASHGWTREQADAFATLCRDAGFGEVEVSERPRGRKSVWLVSAIKR-----
Mb0336c|M.bovis_AF2122/97 DPAIYRVPPTLDTAAWLGAAGFIDVGIKRSADHPATVWFTATAT------
Rv0329c|M.tuberculosis_H37Rv DPAIYRVPPTLDTAAWLGAAGFIDVGIKRSADHPATVWFTATAT------
MLBr_01723|M.leprae_Br4923 ADLTWKVTIRVVQLPGLSAWRRTQVEIDENSRAAALEWVVDLHTFEPKVL
MMAR_1663|M.marinum_M STLTWRIATNVTKLPGLGGWRRPQEELDESSRAAALEAIVDLHTFAPEDL
TH_1968|M.thermoresistible__bu GDEHDPLSKTVTLPEPFTDVQRHQVEWTNYLTPQALIDLVASRSYCITSP
MUL_2765|M.ulcerans_Agy99 AASKWKPQHSPSPAEMRALFEGAGFTISDQHRVRRPVWTRLVPDLITVGT
MAV_4426|M.avium_104 IARPWSWLAGGCEPNRRTGAAIAAAGFDTSMLRSVPRTPVPFPCKPHLQG
MAB_1294c|M.abscessus_ATCC_199 WLHRYYRLRYGWWEHPSPVSCEGLDSHDEVRRIAQRVLPGARLQRLVLWR
Mflv_4035|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2319|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2632|M.smegmatis_MC2_155 --------------------------------------------------
Mb0336c|M.bovis_AF2122/97 --------------------------------------------------
Rv0329c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01723|M.leprae_Br4923 ETMATNAGAVQVKTVTEEFTAAMLGWPLRTFESTMPPSKLGWGWARFAFT
MMAR_1663|M.marinum_M ERMAKNAGAIRVETASEEFSAAMFGWPVRTFESSVPPGRLGWNWARFAFN
TH_1968|M.thermoresistible__bu AKVRARTLERVRELLATHPALANNSGLALPYITVCIRATLA---------
MUL_2765|M.ulcerans_Agy99 KS------------------------------------------------
MAV_4426|M.avium_104 FAVLSSR-------------------------------------------
MAB_1294c|M.abscessus_ATCC_199 HLLTWEKS------------------------------------------
Mflv_4035|M.gilvum_PYR-GCK ---------------------------------
Mvan_2319|M.vanbaalenii_PYR-1 ---------------------------------
MSMEG_2632|M.smegmatis_MC2_155 ---------------------------------
Mb0336c|M.bovis_AF2122/97 ---------------------------------
Rv0329c|M.tuberculosis_H37Rv ---------------------------------
MLBr_01723|M.leprae_Br4923 SWKTLSWVDANVWRRVIPKSWFYNIIITGVKPS
MMAR_1663|M.marinum_M GWKALSWMDANVWRHVAPKGWFYNVMVTGVKPS
TH_1968|M.thermoresistible__bu ---------------------------------
MUL_2765|M.ulcerans_Agy99 ---------------------------------
MAV_4426|M.avium_104 ---------------------------------
MAB_1294c|M.abscessus_ATCC_199 ---------------------------------