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MRLTHPARRYLSSQAARPTGAFGRLLGRIWRAETADVNRIAVELLAPGPGERVCEIGFGPGRTLGLLAAA GAQVSGVEVSTTMIAIAAHHNAKAIAAGLISLYHGDGVTLPVADHSLDKVLGVHNFYFSPDPRASLCDIA RALRPGGRLVLTSISDDQPLAARFDPAIYRVPPTLDTAAWLGAAGFIDVGIKRSADHPATVWFTATAT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0336c | - | - | 100% (208) | hypothetical protein Mb0336c |
| M. bovis AF2122 / 97 | Mb3756 | - | 1e-08 | 31.20% (125) | transferase |
| M. bovis AF2122 / 97 | Mb1550 | - | 3e-08 | 31.20% (125) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4035 | - | 8e-11 | 30.60% (134) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv0329c | - | 1e-117 | 99.52% (208) | hypothetical protein Rv0329c |
| M. leprae Br4923 | MLBr_02273 | ubiE | 5e-08 | 28.91% (128) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. abscessus ATCC 19977 | MAB_3930c | - | 1e-08 | 29.53% (149) | ubiquinone/menaquinone biosynthesis methlytransferase UbiE |
| M. marinum M | MMAR_0907 | ubiE | 3e-08 | 32.85% (137) | ubiquinone/menaquinone methlytransferase, MenH |
| M. avium 104 | MAV_2988 | - | 1e-09 | 27.01% (174) | ubiquinone/menaquinone biosynthesis methyltransferases |
| M. smegmatis MC2 155 | MSMEG_0098 | - | 6e-10 | 36.21% (116) | methyltransferase |
| M. thermoresistible (build 8) | TH_0087 | - | 8e-09 | 29.92% (127) | methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_0660 | ubiE | 3e-08 | 31.39% (137) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0109 | - | 2e-09 | 32.38% (105) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0336c|M.bovis_AF2122/97 -------------MRLTHPARRYLSSQAARPTG---------------AF
Rv0329c|M.tuberculosis_H37Rv -------------MRLTHPARRYLSSQAARPTG---------------AF
MSMEG_0098|M.smegmatis_MC2_155 ---MDTALRRAMDLLIDPPAEPDFSKGYLDLLGRGDSTAPKNTGLIQKAW
Mvan_0109|M.vanbaalenii_PYR-1 --MTHTVLRMTERLLIDPPEHPDTSKGYLDLLG---DEPDSNRGAIQALW
MMAR_0907|M.marinum_M ------------MSRAALDKDPRDVASMFDGVAR--------------RY
MUL_0660|M.ulcerans_Agy99 ------------MSRAALDKDPRDVASMFDGVAR--------------RY
MLBr_02273|M.leprae_Br4923 ----MPPGSVDVVSRAALDKDPRDVVAMFDDVAH--------------RY
MAB_3930c|M.abscessus_ATCC_199 ------------MNRATLEKDPHEVASMFDAVAR--------------RY
MAV_2988|M.avium_104 -----------MGQVTDHWRAARLASALYDTAAMHDR-----------VA
Mflv_4035|M.gilvum_PYR-GCK ---------------MDGSERPVNHHGDHPGFSG--------------LT
TH_0087|M.thermoresistible__bu MLTVDYDRLGIGPGVSVIDVGCGLGRHSFEAYRRG-----------AHIV
Mb0336c|M.bovis_AF2122/97 GRLLGRIWRAETADVNR-------IAVELLAPGPGERVCEIGFGPGRTL-
Rv0329c|M.tuberculosis_H37Rv GRLLGRIWRAETADVNR-------IAVELLAPGPGERVCEIGFGPGRTL-
MSMEG_0098|M.smegmatis_MC2_155 ASPLGSKLYDRAQLLNRRLVASTRPPVEWLRIPPGGTVLDIGCGPGNIT-
Mvan_0109|M.vanbaalenii_PYR-1 ASRLGSMFYDNAQTLARRLMTAWQQPTEWLNVPVGGTALDVGSGPGNVT-
MMAR_0907|M.marinum_M DLTNTVLSLGQDRYWRR-------ATRSALRIGPGDKVLDLAAGTAVST-
MUL_0660|M.ulcerans_Agy99 DLTNTVLSLGQDRYWRR-------ATRSALRIGPGDKVLDLAAGTAVSS-
MLBr_02273|M.leprae_Br4923 DLTNTVLSLGQDRYWRR-------ATRSALRIGPGQKVLDLAAGTAVST-
MAB_3930c|M.abscessus_ATCC_199 DITNTVLSFGRDRFWRR-------ATREALRLKPGDKVLDIAAGTAVST-
MAV_2988|M.avium_104 AVGAKALWGLALRDLLA-------EVRHVGAAPPGAYVLDIPCGGGFAFR
Mflv_4035|M.gilvum_PYR-GCK GQLCAVAFLLTGRETGR-------LAADLTAVSATDHVLDIGCGPGNAC-
TH_0087|M.thermoresistible__bu AFDQNAEELNEVDTILQAMAEQREAPAGARAEVVKGDALDLPYADGTFDR
. :: . .
Mb0336c|M.bovis_AF2122/97 GLLAAAGAQVSGVEVSTTMIAIAAHHNAKAIAAGLISLYHGDGVTLPVAD
Rv0329c|M.tuberculosis_H37Rv GLLAAAGAQVSGVEVSTTMIAIAAHHNAKAIAAGLISLYHGDGVTLPVAD
MSMEG_0098|M.smegmatis_MC2_155 AQLARA-AGLDGLALGVDISEPMLARAVAAEAGRQVGFVRADAQQLPFRD
Mvan_0109|M.vanbaalenii_PYR-1 GALGRA-VGPGGLALGVDISEPMLARAVRAEAGPNVGFIRADAQHLPFRD
MMAR_0907|M.marinum_M VELAKSGAWCVAADFSVGMLAAGHERKVCKVAG--------DATRLPFAD
MUL_0660|M.ulcerans_Agy99 VELAKSGAWCVAADFSVGMLAAGHERRVCKVAG--------DATRLPFAD
MLBr_02273|M.leprae_Br4923 AELSKSGAWCVAADFSVRMLATGGARKVPKVAA--------DATQLPFSD
MAB_3930c|M.abscessus_ATCC_199 AELTQSGAWCVAADFSVGMLKAGARRDVPKVAG--------DATRLPFAD
MAV_2988|M.avium_104 GLRAGQDCRYVAADISSDMLRRARSRATRFGVANLMEFTEADITCLPFPD
Mflv_4035|M.gilvum_PYR-GCK RIAAARGARVTGVDPSAAMLRVARIVTHGASVT----WVRGGAEALPVPD
TH_0087|M.thermoresistible__bu VIASEILEHVPEDDRAIAELVRVLKPGGKLVVT--VPRWLPERICWLLSD
. . . *
Mb0336c|M.bovis_AF2122/97 HSLDKVLGVHNFYFSPDPRASLCDIARALRPGGRLVLTSISDD-------
Rv0329c|M.tuberculosis_H37Rv HSLDKVLGVHNFYFWPDPRASLCDIARALRPGGRLVLTSISDD-------
MSMEG_0098|M.smegmatis_MC2_155 EVFDAATSLAVFQLIPDPVAAVSEIVRVLKPGGRVAIMVPTAG-------
Mvan_0109|M.vanbaalenii_PYR-1 ESFDAVVSIAMLQLIPDPAVALAEMVRVLRPGRRMAVMVPTAGP------
MMAR_0907|M.marinum_M DVFDAVTISFGLRNVVDFSAALREMARVTRPGGRLVVCEFSTPVSALFAT
MUL_0660|M.ulcerans_Agy99 DVFDAVTISFGLRNVVDFSAALREMARVTRPGGRLVVCEFSTPVSALFAT
MLBr_02273|M.leprae_Br4923 GVFDAVTISFGLRNIADYQAALREMARVTRPGGQLVVCEFSTPTNALVAN
MAB_3930c|M.abscessus_ATCC_199 HSFDAVTISFGLRNVVDHVEGLREMARVTKPGGRLAVCEFSTPVNRPFRT
MAV_2988|M.avium_104 NTFDLALTFNGLHCLPDPRAAVFELARVLKPGGILRGTTCVRGR------
Mflv_4035|M.gilvum_PYR-GCK AGATVAWALATVHHWPDVDAGLAEIHRALGPGARFLAVERQTEP------
TH_0087|M.thermoresistible__bu EYHANEGGHVRIYRADELRDKITRHG--LRLTHRHHAHALHSPFWWLKCA
. : :
Mb0336c|M.bovis_AF2122/97 --------------------QPLAARFDPAIYRVPPTLDTAAWLGAAGFI
Rv0329c|M.tuberculosis_H37Rv --------------------QPLAARFDPAIYRVPPTLDTAAWLGAAGFI
MSMEG_0098|M.smegmatis_MC2_155 -------------------AVKPVTFLARGGARIFGDDELGDIFENVGLV
Mvan_0109|M.vanbaalenii_PYR-1 -------------------AAGLLRYLPNAGAHAFGDDELGDTFESLGLA
MMAR_0907|M.marinum_M VYKEYLMRALPRVARAVSSNPEAYVYLAESIRAWPDQAALAQQMSRAGWS
MUL_0660|M.ulcerans_Agy99 VYKEYLMRALPRVARAVSSNPEAYVYLAESIRAWPDQAALAQQMSRAGWS
MLBr_02273|M.leprae_Br4923 VYTEYLMRALPQVARLVSSNPDAYIYLAESIRAWPDQVTLACQLSRTGWA
MAB_3930c|M.abscessus_ATCC_199 LYMEYLMKTLPEVARAVSSNPDAYVYLAESIRAWPDQEALAHQIASAGWS
MAV_2988|M.avium_104 -----------------GWRQDRFVTALQAAGFFGNTPGAGDVSRWLGEA
Mflv_4035|M.gilvum_PYR-GCK ----------------------DATGISSHGWTGAQAETFAAMCESAGLT
TH_0087|M.thermoresistible__bu VG------------------TNNDRHFAVRAYHQLLVWDMVRRPWVTRWA
Mb0336c|M.bovis_AF2122/97 DVGIKRSADHPATVWFTATAT-----
Rv0329c|M.tuberculosis_H37Rv DVGIKRSADHPATVWFTATAT-----
MSMEG_0098|M.smegmatis_MC2_155 GVRVK---THGFIQWVRGTKL-----
Mvan_0109|M.vanbaalenii_PYR-1 GVRIN---TVGTIQWVRGRKS-----
MMAR_0907|M.marinum_M AVRWRN-LTGGIVALHAGYKPQPV--
MUL_0660|M.ulcerans_Agy99 AVRWRN-LTGGIVALHAGYKPQPV--
MLBr_02273|M.leprae_Br4923 SPRWRN-LTGGIVALHAADKPVR---
MAB_3930c|M.abscessus_ATCC_199 NVRWRN-LTGGIVALHIATL------
MAV_2988|M.avium_104 GLEIVAARHSGSVELFEAVRPSA---
Mflv_4035|M.gilvum_PYR-GCK TVRVGSGRAGKRRVWTVHATRP----
TH_0087|M.thermoresistible__bu EEMLNPLIGKSVALYFDKPEVAGADS