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M. avium 104 MAV_4426 (-)

annotation: methyltransferase, UbiE/COQ5 family protein
coordinates: 4563677 - 4564303
length: 208

RFRNVLFPYVYRFGQPVFDRLFYQRYRRQAMSHATGRLLMVGLGPGTDLMFLPAAVTSVAAVEPEASFRR
MAARLAARQGVAVDVVAGSGESIPFPDNSFDSVHIGLVLCSVRDVGATLAEIRRVLVPGGRLVVLEHVRG
DGLTGRLQDLIARPWSWLAGGCEPNRRTGAAIAAAGFDTSMLRSVPRTPVPFPCKPHLQGFAVLSSR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4426--100% (208)methyltransferase, UbiE/COQ5 family protein
M. avium 104MAV_1288-1e-2138.55% (179) hypothetical protein MAV_1288
M. avium 104MAV_4584ubiE3e-1040.68% (118) ubiquinone/menaquinone biosynthesis methyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1178-2e-2241.52% (171) hypothetical protein Mb1178
M. gilvum PYR-GCKMflv_2133-1e-2341.30% (184) methyltransferase type 12
M. tuberculosis H37RvRv1147-2e-2241.52% (171) hypothetical protein Rv1147
M. leprae Br4923MLBr_02273ubiE8e-0836.44% (118) ubiquinone/menaquinone biosynthesis methyltransferase
M. abscessus ATCC 19977MAB_1291-3e-2137.02% (181) hypothetical protein MAB_1291
M. marinum MMMAR_4303-7e-2440.51% (158) hypothetical protein MMAR_4303
M. smegmatis MC2 155MSMEG_5176-2e-2338.25% (183) methyltransferase type 11
M. thermoresistible (build 8)TH_1988-4e-1740.98% (122) methyltransferase type 11
M. ulcerans Agy99MUL_0991-5e-2440.51% (158) hypothetical protein MUL_0991
M. vanbaalenii PYR-1Mvan_4571-4e-2440.54% (185) methyltransferase type 12

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2133|M.gilvum_PYR-GCK          -----------MSDVVDNPFFARLWTAMS-SREPE--SLRRLRRDNLAGL
Mvan_4571|M.vanbaalenii_PYR-1       -----------MNDSVDNPFFARLWTLMS-SREPE--SLRRLRRENLAGL
MSMEG_5176|M.smegmatis_MC2_155      ----MPPTDAAQPEPVDNPFFAWLWKTLS-THETE--SVRRMRAENLAGL
TH_1988|M.thermoresistible__bu      -----------MTSTVDNPFFARMWTWLS-SHEPE--AMRQRREQLLAGL
Mb1178|M.bovis_AF2122/97            ----MTSGAAASASRVDHPLFARIWPVVA-AHEAE--AIRALRRENLAGL
Rv1147|M.tuberculosis_H37Rv         ----MTSGAAASASRVDHPLFARIWPVVA-AHEAE--AIRALRRENLAGL
MMAR_4303|M.marinum_M               ----MTS----LAKNIDHPFFARIWPFIV-AHEAE--PVRALRRENLAGL
MUL_0991|M.ulcerans_Agy99           ----MTS----LAKNIDHPFFARIWPFIV-AHEAE--PVRALRRENLAGL
MAB_1291|M.abscessus_ATCC_1997      ---------MTTPVSFDNRFFSATWSAIA-RREPQ--EIKELRAENLRGL
MAV_4426|M.avium_104                -------------MRFRNVLFPYVYRFGQPVFDRL--FYQRYRRQAMSHA
MLBr_02273|M.leprae_Br4923          MPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYDLTNTVLSLGQDRYWRRA
                                                        .   :       :         :       

Mflv_2133|M.gilvum_PYR-GCK          TGRVLEVGAG-----TGTNFEFYPSTVTEVVAVEPERRLAVLAEQAAAGA
Mvan_4571|M.vanbaalenii_PYR-1       TGRVLEVGAG-----TGTNFEFYPATVTEVVAVEPEHRLATLAQDAAARA
MSMEG_5176|M.smegmatis_MC2_155      SGRVLEVGAG-----TGTNFEFYPSTVDEVVAIEPERRLADVARQAAAKA
TH_1988|M.thermoresistible__bu      SGRVLEVGAG-----TGTNFAFYPPGVTEVVAVEPEQRLVAVVRQAAAEA
Mb1178|M.bovis_AF2122/97            SGRVLEVGAG-----VGTNFAYYPVAVEQVIAMEPEPRLAAKARIAAADA
Rv1147|M.tuberculosis_H37Rv         SGRVLEVGAG-----VGTNFAYYPVAVEQVIAMEPEPRLAAKARIAAADA
MMAR_4303|M.marinum_M               SGRVLEIGAG-----MGTNFAFYPQTVTEVVAVEPEPHLALRARAAGEDA
MUL_0991|M.ulcerans_Agy99           SGRVLEIGAG-----MGTNFAFYPQTVTEVVAVEPEPHLALRARAAGEDA
MAB_1291|M.abscessus_ATCC_1997      TGHVLEVGAG-----IGSNFLLYPNTVTAVTALEPESRLRPQAEDAAAGA
MAV_4426|M.avium_104                TGRLLMVGLG-----PGTDLMFLPAAVTSVAAVEPEASFRRMAARLAARQ
MLBr_02273|M.leprae_Br4923          TRSALRIGPGQKVLDLAAGTAVSTAELSKSGAWCVAADFSVRMLATGGAR
                                    :   * :* *      .:.    .  :    *      :       .   

Mflv_2133|M.gilvum_PYR-GCK          AVPVTVSTDTVEQFADA--KPFDAVVCSLVLCSVDDPEQVVSQLFSVLKP
Mvan_4571|M.vanbaalenii_PYR-1       AVPITVTTDTVEEFTDA--EPFDAVVCSLVLCSVDKPEDVVAELLSMLKP
MSMEG_5176|M.smegmatis_MC2_155      PVPVSVTGDTIETFASA--QPFDAVVCSLVLCSVDDPEQVVGQLYSLLRP
TH_1988|M.thermoresistible__bu      PVPVTVRAETVENFDSS--EPFDAVVCTLVLCSVDDPAGVVRQLFSLLRP
Mb1178|M.bovis_AF2122/97            PVPIVVTDKTVEEFRDT--ETFDAVVCSLVLCSVSDPGAVLAHLRSLLRR
Rv1147|M.tuberculosis_H37Rv         PVPIVVTDKTVEEFRDT--ETFDAVVCSLVLCSVSDPGAVLAHLRSLLRR
MMAR_4303|M.marinum_M               PIPVTVTADTAEQFSDQ--DPFDAVVCSLVLCSVTDQLGVLQHLRSLLRP
MUL_0991|M.ulcerans_Agy99           PIPVTVTADTAEQFSDQ--DPFDAVVCSLVLCSVTDQLGVLQHLRSLLRP
MAB_1291|M.abscessus_ATCC_1997      AIPVTVTAGVFEDLAVTGEDRFDAVVCSLVLCSVGDPDRAAAQAFEVLKP
MAV_4426|M.avium_104                GVAVDVVAGSGESIPFP-DNSFDSVHIGLVLCSVRDVGATLAEIRRVLVP
MLBr_02273|M.leprae_Br4923          KVPKVAADATQLPFSDG---VFDAVTISFGLRNIADYQAALREMARVTRP
                                     :.  .       :       **:*   : * .: .   .  .   :   

Mflv_2133|M.gilvum_PYR-GCK          GGELRYLEHVASDGAARGRLQRFADATFWPRLLGNCHTHRRTEDTITRAG
Mvan_4571|M.vanbaalenii_PYR-1       GGQLRYLEHIAAEGG-RARLQRFADATVWPRLLGNCHTHRHTEETIVGAG
MSMEG_5176|M.smegmatis_MC2_155      GGELRYLEHVAGTGF-QARLQRLADATVWPKLFGGCHTHRHTEQVIASSG
TH_1988|M.thermoresistible__bu      GGELRYLEHIASAGA-RGRLQRFADXR-----------------------
Mb1178|M.bovis_AF2122/97            GGELRYLEHVASAGA-RGRVQRFVDATFWPRLAGNCHTHRHTERAILDAG
Rv1147|M.tuberculosis_H37Rv         GGELRYLEHVASAGA-RGRVQRFVDATFWPRLAGNCHTHRHTERAILDAG
MMAR_4303|M.marinum_M               GGELRYLEHIASAGA-RGRLQQFVDATFWPRIAGNCHTHRDTERVIKAAG
MUL_0991|M.ulcerans_Agy99           GGELRYLEHIASAGA-RGRLQQFVDATFWPRIAGNCHTHRDTERVIKAAG
MAB_1291|M.abscessus_ATCC_1997      GGEVRFFEHVAHDGA-LGLVQRAVDATFWPRLFGNCHTHRDTLAAIERAG
MAV_4426|M.avium_104                GGRLVVLEHVRGDGL-TGRLQDLIARP-WSWLAGGCEPNRRTGAAIAAAG
MLBr_02273|M.leprae_Br4923          GGQLVVCEFSTPTNALVANVYTEYLMRALPQVARLVSSNPDAYIYLAESI
                                    **.:   *.    .   . :                              

Mflv_2133|M.gilvum_PYR-GCK          --------FRVDDARREWTFPAWVPVPVAEFAIGVARRP--
Mvan_4571|M.vanbaalenii_PYR-1       --------FRVRDARREWTFPRWVPLPVAEFAIGVAVKP--
MSMEG_5176|M.smegmatis_MC2_155      --------FGVRGRRREQVLPAWVPVPTTEFAIGRAVRP--
TH_1988|M.thermoresistible__bu      -----------------------------------------
Mb1178|M.bovis_AF2122/97            --------FVVDSSRREWAFPAWVPLPVSELALGRAHRT--
Rv1147|M.tuberculosis_H37Rv         --------FVVDSSRREWAFPAWVPLPVSELALGRAHRT--
MMAR_4303|M.marinum_M               --------FDVESTRREWTLPTWAPVPVAELVLGRARRP--
MUL_0991|M.ulcerans_Agy99           --------FDVESTRREWTLPTWAPVPVAELVLGRARRP--
MAB_1291|M.abscessus_ATCC_1997      --------FTIEERRDDWLKVMGIPMPSSSIVIGRAVKPA-
MAV_4426|M.avium_104                --------FDTSMLRS--VPRTPVPFPCKPHLQGFAVLSSR
MLBr_02273|M.leprae_Br4923          RAWPDQVTLACQLSRTGWASPRWRNLTGGIVALHAADKPVR