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ATVDNEDDRALKAKHRALWASGDYPAVAAELIPSLGPELVRACGVRSGDRVLDVAAGSGNASIPAAAAGA VVTASDLTPELFDAGRRIAAERGVAVEWVEADAEALPFPDDSFDVVMSCVGAMFAPHHQATADEIVRVTR PGGTLGLISWTPEGFIGHLFATMKPYAPPPPPGASPPPMWGSENHVEALFGDRVRDLTMRRQTVRFDHCA SPLDFREYWKRNYGPTLAAYRFNEDRPERLAELDAAFLDFLTTWNQADGTDGTAYDAEYLLVTATKR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4060 | - | - | 100% (278) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_4692 | - | 4e-23 | 31.82% (264) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_5258 | ubiE | 3e-09 | 39.18% (97) | ubiquinone/menaquinone biosynthesis methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1438c | - | 2e-68 | 51.15% (262) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv1403c | - | 2e-68 | 51.15% (262) | putative methyltransferase |
| M. leprae Br4923 | MLBr_00551 | - | 2e-63 | 47.04% (270) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_4103c | - | 3e-11 | 39.80% (98) | methyltransferase |
| M. marinum M | MMAR_1627 | - | 9e-87 | 58.15% (270) | methyltransferase |
| M. avium 104 | MAV_3373 | - | 2e-67 | 48.52% (270) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_2285 | - | 4e-88 | 58.89% (270) | methyltransferase type 11 |
| M. thermoresistible (build 8) | TH_2937 | - | 3e-21 | 31.29% (278) | PUTATIVE Methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_3409 | - | 1e-86 | 58.15% (270) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2287 | - | 1e-123 | 75.74% (272) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1438c|M.bovis_AF2122/97 ---------------MTVYTP----TSERQAPATTHRQMWALG--DYAAI
Rv1403c|M.tuberculosis_H37Rv ---------------MTVYTP----TSERQAPATTHRQMWALG--DYAAI
MLBr_00551|M.leprae_Br4923 ---------------MNLYTP----IHEDQSLAAIHRAMWALG--DYALM
MAV_3373|M.avium_104 ---------------MTLDT-----TTADASVAARHRTVWALG--DYALM
Mflv_4060|M.gilvum_PYR-GCK ---------------MATVDN-----EDDRALKAKHRALWASG--DYPAV
Mvan_2287|M.vanbaalenii_PYR-1 ---------------MSTTATSASAHDADRQLKAKHRALWASG--DYPAV
MMAR_1627|M.marinum_M ---------------MTTLARTE---PTDRGYESKHRALWALG--DYPAV
MUL_3409|M.ulcerans_Agy99 ---------------MTTLARTE---PTDRGYESKHRALWALG--DYPAV
MSMEG_2285|M.smegmatis_MC2_155 ---------------MGVVT-------VDRELEAKHRALWALG--NYGAI
TH_2937|M.thermoresistible__bu -----------------------------------VTTNWAAG--RYEAV
MAB_4103c|M.abscessus_ATCC_199 MQRSRDWVMFKLNAVFTQRVQKFIYRHATRKLETEDVVFLNYGYEEEPAM
* :
Mb1438c|M.bovis_AF2122/97 AEELLAPLGP------ILVSTSGIR--RGDRVLDVAAGSGN--VSIPAAM
Rv1403c|M.tuberculosis_H37Rv AEELLAPLGP------ILVSTSGIR--RGDRVLDVAAGSGN--VSIPAAM
MLBr_00551|M.leprae_Br4923 AEEVMAPLGP------ILVTATGIR--PGMQVLDVAAGSGN--ISLPAAK
MAV_3373|M.avium_104 AEEVMAPLGP------TLVEAAGIG--PGVRVLDVAAGSGN--ITLPAAA
Mflv_4060|M.gilvum_PYR-GCK AAELIPSLGP------ELVRACGVR--SGDRVLDVAAGSGN--ASIPAAA
Mvan_2287|M.vanbaalenii_PYR-1 AAELIAELGP------ELVRACGIQ--AGDRVLDVAAGSGN--AAIPAAE
MMAR_1627|M.marinum_M ATDLVSPLGP------ILLEATRIS--AGDRVLDVAAGSGN--VAIPAAL
MUL_3409|M.ulcerans_Agy99 ATDLVSPLGP------ILLEATRIS--AGDRVLDVAAGSGN--VAIPAAL
MSMEG_2285|M.smegmatis_MC2_155 AAHIVAPLGP------VLVEACGIG--PGDRVLDIAAGTGN--ASIPAAL
TH_2937|M.thermoresistible__bu GERIAPIADE------VLDAAARRTPLRGATLVDLACGTGS--AALSATA
MAB_4103c|M.abscessus_ATCC_199 GVPLSASDEPDRYSIQLYHSTATQADLGGQRVLEVGCGHGGGASYLVRAL
. : . : * ::::..* *. : :
Mb1438c|M.bovis_AF2122/97 AGAHVTASDLTPELLRRAQARAAAAGLELGWREANAEALPFSAGEFDAVL
Rv1403c|M.tuberculosis_H37Rv AGAHVTASDLTPELLRRAQARAAAAGLELGWREANAEALPFSAGEFDAVL
MLBr_00551|M.leprae_Br4923 TGATIVSTDLTPELLQRSQARATELGLTLEYREADAQALPFGDGEFDVVM
MAV_3373|M.avium_104 AGASVVSTDLTPELLQRSRDRAAGMGLTIDYREANAQALPFGDGEFDAVV
Mflv_4060|M.gilvum_PYR-GCK AGAVVTASDLTPELFDAGRRIAAERGVAVEWVEADAEALPFPDDSFDVVM
Mvan_2287|M.vanbaalenii_PYR-1 VGAIVTASDLTPELFGAGRRIAAERGVDLEWVEADAESLPFADGSFDVVM
MMAR_1627|M.marinum_M AGADVIASDLCPNLLECGRGLAAARGASLRWVEANAQALPFDTDEFDAVV
MUL_3409|M.ulcerans_Agy99 AGADVIASDLCPNLLECGRGLAAARGASLRWVEANAQALPFDTDEFDAVV
MSMEG_2285|M.smegmatis_MC2_155 AGAQVTASDLCPQLVDEGAHESAERGVDITWKEANAEALPFSDGEFDVVM
TH_2937|M.thermoresistible__bu RGAAVTGVDITSELIALAAG--KPGGSTVTWVTADAADTGLKTASFDVAV
MAB_4103c|M.abscessus_ATCC_199 QPASYTGLDLNPDGISFCRRRHDLPG--LEFVQGDAEDLPFPDESFDAVI
* . *: .: . * : : .:* : .**..:
Mb1438c|M.bovis_AF2122/97 STIGVMFAPRHQRTADELARVCRRGGKISTLNWTPEGFYGKLLSTIRPYR
Rv1403c|M.tuberculosis_H37Rv STIGVMFAPRHQRTADELARVCRRGGKISTLNWTPEGFYGKLLSTIRPYR
MLBr_00551|M.leprae_Br4923 SAIGVMFAPDHRRAASELVRVCRPNGTIGVISWTQEGFFGRMLATIRPYR
MAV_3373|M.avium_104 SAIGVQFAPDHQRAADELVRVCRPGGRIGLISWTPEGFFGRMLATIRPYR
Mflv_4060|M.gilvum_PYR-GCK SCVGAMFAPHHQATADEIVRVTRPGGTLGLISWTPEGFIGHLFATMKPYA
Mvan_2287|M.vanbaalenii_PYR-1 SCVGAMFAPHHQATADELIRVCRPGGTIGMVNWTPGGFIGNLFATMKPYA
MMAR_1627|M.marinum_M SCVGVMFAPYHQPCADELVRVCRPGGVIGLISWTPGGFIGEMFTTMKPYL
MUL_3409|M.ulcerans_Agy99 SCVGVMFAPYHQPCADGLVRVCRPGGVIGLISWTPGGFIGEMFTTMKPYL
MSMEG_2285|M.smegmatis_MC2_155 SCIGVMFAPHHDQSARELLRVTRSGGRIGLISWTPEGFIGQLFATMKPFV
TH_2937|M.thermoresistible__bu SNMGIIFVP-PDRQVAELARLLKPGGVLSFSAWIRTDEN-PFSDPVAEVL
MAB_4103c|M.abscessus_ATCC_199 NVESSHLYPHFPVFLTEVARVLRPGG----------NFLYTDARSVQDVA
. . : * : *: : .* . .:
Mb1438c|M.bovis_AF2122/97 PTLPAGAPHEVWWGSEDYVSGLFRDHVSDIRTRRGSLTVDRFGCPDECRD
Rv1403c|M.tuberculosis_H37Rv PTLPAGAPHEVWWGSEDYVSGLFRDHVSDIRTRRGSLTVDRFGCPDECRD
MLBr_00551|M.leprae_Br4923 PSLSAALPPAALWGREAYIRGLLDDTVTNVKTERRQLEVKRFNSAEGVHN
MAV_3373|M.avium_104 PSLSHPVPPAALWGRPGYVRALLGERIGEITTARGMLPVNRFGSAEDVHA
Mflv_4060|M.gilvum_PYR-GCK PPPPPGASPPPMWGSENHVEALFGDRVRDLTMRRQTVRFDHCASPLDFRE
Mvan_2287|M.vanbaalenii_PYR-1 PPPPPGANPPPLWGDTDHVTTLFGDRVGDLTTRRQTVRMDHCADPAGFRE
MMAR_1627|M.marinum_M APPLPGAQPAPLWGTEGHVRELFADRVTDFAVRRGALLVDEFADGASFRD
MUL_3409|M.ulcerans_Agy99 APPLPGAQPAPLWGTEGHVRELFADRVTDFAVRRGTLLVDEFADGASFRD
MSMEG_2285|M.smegmatis_MC2_155 PAPPPGVSPPPLWGNADHVRTLLGDGIEDFETQRRSLTVDMFADGAAFRD
TH_2937|M.thermoresistible__bu GPPPAGFSPD-QWGDAETLTERLTPHFDAIDLIRG-LHPWEFDSPATALH
MAB_4103c|M.abscessus_ATCC_199 GWKVALANAPLRMVSERGINAEVRRGMEKNLARWRYVIDR--ATPAPLRG
: . . :
Mb1438c|M.bovis_AF2122/97 YFKNFYGPAINAYRSIADSPECVATLDAEITELCREYLCD-----GVMQW
Rv1403c|M.tuberculosis_H37Rv YFKNFYGPAINAYRSIADSPECVATLDAEITELCREYLCD-----GVMQW
MLBr_00551|M.leprae_Br4923 YFKNHYGPTIEAYTNIGDNSVLAAELDAQLTELAQKYLTN-----STMGW
MAV_3373|M.avium_104 YFKQHYGPTIEAYANIGHNRVLAAELDAQLVELAAQHLSD-----GTMGW
Mflv_4060|M.gilvum_PYR-GCK YWKRNYGPTLAAYRFNEDRPERLAELDAAFLDFLTTWNQADGTDGTAYDA
Mvan_2287|M.vanbaalenii_PYR-1 YWKRNYGPTIAAYRFNAGHADRIGALDRDFLALLTEWNRGDETN-AFWEA
MMAR_1627|M.marinum_M YFKANYGPTIAAYRAIAAEPDRVAALDAELAALGDRYLAG----SSAMEW
MUL_3409|M.ulcerans_Agy99 YFKANYGPTIAAYRAIAAEPDRVAALDAELAALGDRYLAG----SSAMEW
MSMEG_2285|M.smegmatis_MC2_155 FFKANYGPTIAAYRAVGDDAERTAALDEAIALLGDRYLD-----SGAMQW
TH_2937|M.thermoresistible__bu FLRTESPVHVEIFRRAG--PARRERLAAAFRSALRPHAGPAG--TVGFTA
MAB_4103c|M.abscessus_ATCC_199 IVRR-FAPAQRAYDDLRAGGSVEYRMYRFVKA------------------
: : : .
Mb1438c|M.bovis_AF2122/97 EYLIFTARKC--
Rv1403c|M.tuberculosis_H37Rv EYLIFTARKC--
MLBr_00551|M.leprae_Br4923 EYLLLTAQKH--
MAV_3373|M.avium_104 EYLLVTAEKRSG
Mflv_4060|M.gilvum_PYR-GCK EYLLVTATKR--
Mvan_2287|M.vanbaalenii_PYR-1 EYLLVTMTRL--
MMAR_1627|M.marinum_M EYLLVTARKR--
MUL_3409|M.ulcerans_Agy99 EYLLVTARKR--
MSMEG_2285|M.smegmatis_MC2_155 EYLVVTAHKR--
TH_2937|M.thermoresistible__bu PYVIVTARRRG-
MAB_4103c|M.abscessus_ATCC_199 ------------