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AERWTKERRTEHTRQILLDAAEEVFARKGLTGAALEEIADAAGFTRGAIYSQFGAKEKLFLAVVDRQRER FLDGFADVMDSFHRLSDVDIDELAQRWRQLSSGADRAALGYELTLYLLRNPDARASVAAQRRETIRALGE FISKNVARIGGTLTIEAETLARIVLAANDGVTLDSHIDGEDLYRPYLQLVMSSVQTPH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2327 | - | - | 100% (199) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2461 | - | 7e-68 | 62.94% (197) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2460 | - | 1e-57 | 54.50% (200) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 4e-11 | 25.53% (188) | TetR/ACRR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 3e-11 | 25.53% (188) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00949 | - | 2e-07 | 40.62% (64) | hypothetical protein MLBr_00949 |
| M. abscessus ATCC 19977 | MAB_2913 | - | 8e-20 | 31.87% (182) | TetR family regulatory protein |
| M. marinum M | MMAR_4631 | - | 2e-16 | 30.53% (190) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 2e-12 | 31.90% (163) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 6e-54 | 52.00% (200) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3967 | - | 3e-10 | 31.39% (137) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0245 | - | 3e-13 | 29.31% (174) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4321 | - | 1e-101 | 92.42% (198) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2327|M.gilvum_PYR-GCK -------------MAERWTKERRTEHTRQILLDAAEEVFARKGLTGAALE
Mvan_4321|M.vanbaalenii_PYR-1 -------------MAERWTKERRTEHTRQILLDAAEEVFARKGLTGAALE
MSMEG_6807|M.smegmatis_MC2_155 -------------MVERWTRERRLEHTRSLLLDAAENVFSEKGFTAATLD
MMAR_4631|M.marinum_M -------MTPPANTATPARVTKRRAETRARLVDAAFRVFADKGFGHVRIE
MUL_0245|M.ulcerans_Agy99 -------------------------------------MFADKGFGHVRIE
Mb0310|M.bovis_AF2122/97 ------------MGVPAKKKQQQGERSRESILDATERLMATKGYAATSIS
Rv0302|M.tuberculosis_H37Rv ------------MGVPAKKKQQQGERSRESILDATERLMATKGYAATSIS
MAB_2913|M.abscessus_ATCC_1997 MYPYRFTVITTGRLLMSTGSTRRREHTRARLMQAALDVFADRGFHGASIE
MAV_1611|M.avium_104 -------MLLGMSPVKPLRSRPTRGEVRDRILDAAAKVFAAEGFAGATID
MLBr_00949|M.leprae_Br4923 -----------MTTSARTHRWAKTGAIQRRILDAAIEVFATRSFTTATMT
TH_3967|M.thermoresistible__bu -------------MPADNGTARKSDRTRSTILDAARVAFARKGFSGVTIR
:: .. . :
Mflv_2327|M.gilvum_PYR-GCK EIADAAGFTRGAIYSQFGAKEKLFLAVVDRQRERFLDGFADVMDSFHRLS
Mvan_4321|M.vanbaalenii_PYR-1 EIAEAAGFTRGAIYSQFGAKEKLFLAVVDRQRQRFLDGFADVMMSFHRLS
MSMEG_6807|M.smegmatis_MC2_155 DIAFAAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFDNFAEVMASAASVG
MMAR_4631|M.marinum_M DVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISEQVGTAMASVD--D
MUL_0245|M.ulcerans_Agy99 DVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISEQVGTAMASVG--D
Mb0310|M.bovis_AF2122/97 DIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVE
Rv0302|M.tuberculosis_H37Rv DIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVE
MAB_2913|M.abscessus_ATCC_1997 NICEKAGFTRGAFYSNFAGKDELFFTLFDASSEQLLTQLRAALDECRK-S
MAV_1611|M.avium_104 AIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQQIAIALDRSAGDT
MLBr_00949|M.leprae_Br4923 DAMTGSGAIIGSIYHHFGGKRKLFLAIFEQMGRQRRPPHRRGDATSGPIR
TH_3967|M.thermoresistible__bu DITDLAGVTRANFYYYFSDKTELFIELG---TDTYREVLAVAESFGEDMS
.* . .* * :: :
Mflv_2327|M.gilvum_PYR-GCK DVDIDELAQRWRQLSS--GADRAALGYELTLYLLRNPDARASVAAQRRET
Mvan_4321|M.vanbaalenii_PYR-1 DVDIDELAERWRQLSS--GPDRAALGHELTLYLLRNPEARESVAGQRRET
MSMEG_6807|M.smegmatis_MC2_155 ARELDEIAKRWRQLSVDRGAEQAALGLEFTLYLKRNPEARDRVAAKRSEV
MMAR_4631|M.marinum_M PTDVPGTVDRIASTLL-LDRDWLLIKTDFLMHAARHPDLAQRLAAHRAQL
MUL_0245|M.ulcerans_Agy99 PTDVPGTVDRIASTLL-LDRDWLLIKTDFLMHAARHPDLAQRLAAHRAQL
Mb0310|M.bovis_AF2122/97 QRSERQLTELVSLQSQ--HPDFLRLFYLLSMERSQDPVVAAVVRRVRNTA
Rv0302|M.tuberculosis_H37Rv QRSERQLTELVSLQSQ--HPDFLRLFYLLSMERSQDPAVAAVVRRVRNTA
MAB_2913|M.abscessus_ATCC_1997 PDPLSTFIRTIDDKGP-TQRRWYLISMEFTLYAIREPSAAVVLAEHDARL
MAV_1611|M.avium_104 TAAAREVSRSVLDSVR-DHSDYYVLLVEYWLRAQRDPQLRERLIERRRAA
MLBr_00949|M.leprae_Br4923 PSGDRSAAGIRSPRTG--------------------PTSRRCGKTGTRPG
TH_3967|M.thermoresistible__bu RAGIDEWVARXGPVDS------ADLPAQIASLPAQDAAAKLTSAGVRAAV
.
Mflv_2327|M.gilvum_PYR-GCK IRALGEFISKNVAR--IGGTLTIEAETLARIVLAANDGVTLDSHIDG---
Mvan_4321|M.vanbaalenii_PYR-1 VRALGEFISKNVAR--IGGTLTIEAETLARVVLAANDGITLNSHLDG---
MSMEG_6807|M.smegmatis_MC2_155 VAQLTAFIVASIEK--LGATLLISPETFAHALVATSDSVVLSSELDN---
MMAR_4631|M.marinum_M RAAVEDRLAGSDVE--LPAAIGSVAD-AARAVVAAYDGVSIQLLLDGD--
MUL_0245|M.ulcerans_Agy99 RAAVEDRLAGSDVE--LPAAIGSVAD-AARAVVAAYDGVSIQLLLDGD--
Mb0310|M.bovis_AF2122/97 IARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTT
Rv0302|M.tuberculosis_H37Rv IARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTT
MAB_2913|M.abscessus_ATCC_1997 RREAAGIINELMSI--AHRELIIDTELIARLATALREGVAAQFYVEPELA
MAV_1611|M.avium_104 ADQALHIVESTDTVP-----GDRRLTDIAQLVVTLNLGVAMEEVLRPGTI
MLBr_00949|M.leprae_Br4923 CCRPETHLQASRSP----------------VATA----------------
TH_3967|M.thermoresistible__bu VRSATELVGDPHLAARGFFPEIAHPDPQLRTGRLVGLPWRFAGAGPVPLS
:
Mflv_2327|M.gilvum_PYR-GCK --EDLYRPYLQLVMSSVQTPH---
Mvan_4321|M.vanbaalenii_PYR-1 --EDLYRPYLQLVISSVQTPP---
MSMEG_6807|M.smegmatis_MC2_155 --VDLYRPMVEMYASMIKLPT---
MMAR_4631|M.marinum_M --QDAARAWLSQLLGVVLIR----
MUL_0245|M.ulcerans_Agy99 --QDAARAWLSQLLGVVLIR----
Mb0310|M.bovis_AF2122/97 DVERMYRRLRQALEALIPVLLEET
Rv0302|M.tuberculosis_H37Rv DVERMYRRLRQALEALIPVLLEET
MAB_2913|M.abscessus_ATCC_1997 ETRMLERLAFPAMLRAFSQPVGAD
MAV_1611|M.avium_104 N-PDLLAQLITALLESIPV-----
MLBr_00949|M.leprae_Br4923 ------------------------
TH_3967|M.thermoresistible__bu PPPALGSTPASALYERTPV-----