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M. leprae Br4923 MLBr_00949 (-)

annotation: hypothetical protein MLBr_00949
coordinates: 1118771 - 1119184
length: 137

TTSARTHRWAKTGAIQRRILDAAIEVFATRSFTTATMTDAMTGSGAIIGSIYHHFGGKRKLFLAIFEQMG
RQRRPPHRRGDATSGPIRPSGDRSAAGIRSPRTGPTSRRCGKTGTRPGCCRPETHLQASRSPVATA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00949--100% (137)hypothetical protein MLBr_00949

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3587c-6e-0537.21% (43) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_2460-2e-0839.71% (68) TetR family transcriptional regulator
M. tuberculosis H37RvRv3557c-6e-0537.21% (43) TetR family transcriptional regulator
M. abscessus ATCC 19977MAB_4352c-6e-0837.70% (61) TetR family transcriptional regulator
M. marinum MMMAR_4335-4e-2359.55% (89) TetR family transcriptional regulator
M. avium 104MAV_4769-9e-0738.60% (57) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_5346-4e-0838.89% (72) TetR-family protein transcriptional regulator
M. thermoresistible (build 8)TH_4015-5e-0836.49% (74) PUTATIVE -
M. ulcerans Agy99MUL_0145-3e-2359.55% (89) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_4194-5e-0839.71% (68) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4335|M.marinum_M               -----------------------MSTDSHGRRWAKTDATQRRILDAATEV
MUL_0145|M.ulcerans_Agy99           -----------------------MSTDSHGRRWAKTDATQRRILDAATEV
MLBr_00949|M.leprae_Br4923          -----------------------MTTSARTHRWAKTGAIQRRILDAAIEV
Mflv_2460|M.gilvum_PYR-GCK          -------------------------MVERWTRERRLEHTRSVLLDAAEEV
Mvan_4194|M.vanbaalenii_PYR-1       -------------------------MAERWTRERRLEHTRSVLLDAAEEV
Mb3587c|M.bovis_AF2122/97           ----------------------------MDRVAGQVNSRRGELLELAAAM
Rv3557c|M.tuberculosis_H37Rv        ----------------------------MDRVAGQVNSRRGELLELAAAM
MAB_4352c|M.abscessus_ATCC_199      ---------------------------MVPLRQAQALATRQRLVDVATEL
TH_4015|M.thermoresistible__bu      VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKEV
MSMEG_5346|M.smegmatis_MC2_155      ------------------------------MSAELEIDVKTRILDAAADA
MAV_4769|M.avium_104                -----------------MAVDYSELPAEEAVRAARAGARRRQVLDAAVKV
                                                                           :  ::: *   

MMAR_4335|M.marinum_M               FATRGFNAATMAEVVASSGASIGSIYHHFGGKTELFLAI--------FEQ
MUL_0145|M.ulcerans_Agy99           FATRGFNAATMAEVVASSGASIGSIYHHFGGKTELFLAI--------FEQ
MLBr_00949|M.leprae_Br4923          FATRSFTTATMTDAMTGSGAIIGSIYHHFGGKRKLFLAI--------FEQ
Mflv_2460|M.gilvum_PYR-GCK          FAEKGFTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWRRYFDN
Mvan_4194|M.vanbaalenii_PYR-1       FAEKGFTPATLDDIARTAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFDN
Mb3587c|M.bovis_AF2122/97           FAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFAR
Rv3557c|M.tuberculosis_H37Rv        FAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFAR
MAB_4352c|M.abscessus_ATCC_199      FALHGFTSVTTTSLSEASGMTRGALYHHFANMTEVMEAVFERAEGFLVAE
TH_4015|M.thermoresistible__bu      FARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQP
MSMEG_5346|M.smegmatis_MC2_155      FMVHGFANTTIDDIAEQVGATKGLIYYHFRSKFDIFLAVYEDGMRRVRER
MAV_4769|M.avium_104                MGRNGFHRMSMHDLAAEADVSVGLLYKYFGGKQDLLLATIVRILDVFRDQ
                                    :   .:      .     .   * :* :*    .:.              

MMAR_4335|M.marinum_M               MASAV-------EGKIEEALQQAGDETDRRRIFEL---GVRAYLDGLWEH
MUL_0145|M.ulcerans_Agy99           MASAV-------EGKIEEALQQAGDETDRRRIFEL---GVRAYLDGLWEH
MLBr_00949|M.leprae_Br4923          MG------------RQRRPPHRRGDATSG-PIRPS---GDRS-AAGIRSP
Mflv_2460|M.gilvum_PYR-GCK          FAEVM-------SSASRVGADELDEIAERWRQLSID-RGAEHAALGLEFT
Mvan_4194|M.vanbaalenii_PYR-1       FAEVM-------ASASRVGAHELDEIAERWRQLSID-RGADHAALGLEFT
Mb3587c|M.bovis_AF2122/97           YRDIV-------DSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRL
Rv3557c|M.tuberculosis_H37Rv        YRDIV-------DSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRL
MAB_4352c|M.abscessus_ATCC_199      VNHSL-------TSIESPAERFLAIGSAVLDVLAR--EPIVQRIVFVEAP
TH_4015|M.thermoresistible__bu      VRTDAG------TEPKNPYERILRANRTYLEAYRAN--RAIMIVWEQVAS
MSMEG_5346|M.smegmatis_MC2_155      VEPHAGGAGTGRERLVAMSVAHLENLMTELGYHHVVHQGVRYQASTALKI
MAV_4769|M.avium_104                LAPVID------AAGDDVVDQLSAGIRRYIQIVDENLDGVVLTYRESRTL
                                                                                      

MMAR_4335|M.marinum_M               RRVARLLASGDRPTDFGITRRDRMTSAFRSWMAVLELDSSLHGQFLSRAL
MUL_0145|M.ulcerans_Agy99           RRVARLLASGDRPTDFGITRRDRMTSAFRSWMAVLELDSSLHGQFLSRAL
MLBr_00949|M.leprae_Br4923          RTGPTSRRCGKTGTRPGCCRPETHLQASRSPVATA---------------
Mflv_2460|M.gilvum_PYR-GCK          LYLLRNPEARERVEAKRAEVVDQLAEFIVEGMSQLGATLLIEPSTFARAL
Mvan_4194|M.vanbaalenii_PYR-1       LYLLRNPDARERVAAKRAEVVDQLAKFINEGMTRLGASLLISPLTFAQAL
Mb3587c|M.bovis_AF2122/97           ASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTT
Rv3557c|M.tuberculosis_H37Rv        ASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTT
MAB_4352c|M.abscessus_ATCC_199      MALGWSRWRALDGGRSLGLIQDILEELYRRGELVEAVDPQMAAQLILGAI
TH_4015|M.thermoresistible__bu      LNEHVEQLRREYSDRFAARIERAIIRWQEAGLADPAIDPRYAAAALSGML
MSMEG_5346|M.smegmatis_MC2_155      RQRDALAALNELRRDYELMFRRVVAEGIADG-SLRVVDEALATRTLLSNL
MAV_4769|M.avium_104                GAAGRAQIKDLEIATAAPLRAVIETGIAQGVFRSVDVDLAVFDIMLLAHG
                                                                                      

MMAR_4335|M.marinum_M               LAIMEESSLMVAACEEPEQVKPVIDATIEWIGRLTE--------
MUL_0145|M.ulcerans_Agy99           LR--------------------------SWRSRH----------
MLBr_00949|M.leprae_Br4923          --------------------------------------------
Mflv_2460|M.gilvum_PYR-GCK          VATSDSVVLGSQLDAVDLYRPMVEMYVSVIKLPD----------
Mvan_4194|M.vanbaalenii_PYR-1       VATSDSVVLASQLDDIDLYRPVVEMYTSVIKLPD----------
Mb3587c|M.bovis_AF2122/97           WVSVRWYRPGGPLTAQQVGQQYLAIVLGGITKEGV---------
Rv3557c|M.tuberculosis_H37Rv        WVSVRWYRPGGPLTAQQVGQQYLAIVLGGITKEGV---------
MAB_4352c|M.abscessus_ATCC_199      NESGMYAAAAPSERSSRAAEQLTLLCRGLLSPRSG---------
TH_4015|M.thermoresistible__bu      SNFAYRWSVQDADYDLDTAAEQLSLLWANALGVRVPAHHEPAHA
MSMEG_5346|M.smegmatis_MC2_155      NAVDMWYRRIEGQTLDEINELATNVVDLLITGMANPQGRPR---
MAV_4769|M.avium_104                WALKHWHFGPIYTLDEYIALQTRHLLNGLISDERRADYADVLK-