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MSAEERHRNRRTRLIEAAMELIGTHGVAAATVTAVCAESGVTSRYFYQHFPDRDALLRAVYQQLYATFQE VIVDAIPDAGAPPEVLAYAPIRGLVSMINNDPRLGRILFVESATEPLLRELRSDMMTGFTDLVLREARLH LDIADSAVGVAHLASTLGVGGLFEVLRRWLDGELEFTTDELVQHCAGFLGSLGSYVLLQNAVESATTKAK PQS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4630 | - | - | 100% (213) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0331 | - | 1e-20 | 31.03% (203) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5109 | - | 4e-20 | 32.04% (181) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0848c | - | 1e-19 | 30.65% (186) | hypothetical protein Mb0848c |
| M. tuberculosis H37Rv | Rv0825c | - | 1e-19 | 30.65% (186) | hypothetical protein Rv0825c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2068c | - | 1e-65 | 63.35% (191) | putative transcriptional regulator |
| M. marinum M | MMAR_3144 | - | 1e-68 | 61.65% (206) | AcrR family transcriptional regulator |
| M. avium 104 | MAV_3986 | - | 1e-23 | 35.33% (184) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5768 | - | 5e-21 | 34.90% (192) | hypothetical protein MSMEG_5768 |
| M. thermoresistible (build 8) | TH_1575 | - | 4e-21 | 32.43% (185) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0446 | - | 8e-22 | 32.12% (193) | hypothetical protein MUL_0446 |
| M. vanbaalenii PYR-1 | Mvan_0313 | - | 1e-106 | 91.94% (211) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5768|M.smegmatis_MC2_155 MPSGQRRGRWSGVPLRERTALRRDELIAAGVKLLGAADGPALTVRAVCRE
TH_1575|M.thermoresistible__bu ------------VPLSDRQTLRREELIAAGVKLLGHREGPALTVRAVCRE
Mb0848c|M.bovis_AF2122/97 MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCRH
Rv0825c|M.tuberculosis_H37Rv MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCRH
MUL_0446|M.ulcerans_Agy99 MQAGQRRGRWTGVPLEDRHAVRRDTLIAAGVQLLGEEAGPALTVRAVCRQ
MAV_3986|M.avium_104 ---MSSPSRWAGVPLKDRRAERRALLVEAAYRLFGSEGEAAVSVRSVCRE
Mflv_4630|M.gilvum_PYR-GCK ------------MSAEERHRNRRTRLIEAAMELIGTHGVAAATVTAVCAE
Mvan_0313|M.vanbaalenii_PYR-1 ------------MSAEERHRNRRTRLIEAATELIGTRGVAAATVTAVCAE
MAB_2068c|M.abscessus_ATCC_199 ---------------------------------MGTHGATACTVTAVCAK
MMAR_3144|M.marinum_M ---MSPARVYGGLSATQRDAQRRALLIDAAVALMGKQGAAACTVTAVCTE
:* .* :* :** .
MSMEG_5768|M.smegmatis_MC2_155 AGLTERYFYECFNDRDGFVRAVYDDVCATAMSALTAADTPR---------
TH_1575|M.thermoresistible__bu AGLTERYFYESFADRDEFVRAVYDDVCARAMSTLMTADTPR---------
Mb0848c|M.bovis_AF2122/97 AGLTERYFYESFADREHFVRAVYDDVCTRAMATLTSAQTPR---------
Rv0825c|M.tuberculosis_H37Rv AGLTERYFYESFADREHFVRAVYDDVCTRAMATLTSAQTPR---------
MUL_0446|M.ulcerans_Agy99 AALTERYFYESFSDRDHFVRAVYDDVCTRAMATLMSANTPR---------
MAV_3986|M.avium_104 CGLNTRYFYESFRDTDDLLGAVYDRVSEQLEEVIAAAIEQAGDSLRARTR
Mflv_4630|M.gilvum_PYR-GCK SGVTSRYFYQHFPDRDALLRAVYQQLYATFQEVIVDAIPDAGAPPEVLAY
Mvan_0313|M.vanbaalenii_PYR-1 SGVTSRYFYQHFSGRDALLRAVYQQLYATFQEVIVDAIPDAGEPPEVLAY
MAB_2068c|M.abscessus_ATCC_199 SGVTSRYFYQQFRDRDALLRAVFAKISATFQAVITSAIPDDTVAPQELAY
MMAR_3144|M.marinum_M SGVTSRYFYQQFRDRDALLRAMFTKISTTFQAVITKAIPDDTVAPQELAY
..:. ****: * . : :: *:: : .: *
MSMEG_5768|M.smegmatis_MC2_155 KAVEQFVSLMVDDPTRGRVLLLAPESEPVLTR---SGAEWMPNFIDLLQR
TH_1575|M.thermoresistible__bu DAVERFVALMVDDPVRGRVLLLAPEVEPVLTR---SGAKWMPNFIDLLQR
Mb0848c|M.bovis_AF2122/97 EAVEQFVELMVDDPVRGRVLLLAPAVEPALTR---SGAEWMPNFIELLQR
Rv0825c|M.tuberculosis_H37Rv EAVEQFVELMVDDPVRGRVLLLAPAVEPALTR---SGAEWMPNFIELLQR
MUL_0446|M.ulcerans_Agy99 DAVERFVALMVDDPVRGRVLLLAPAVEPVLTR---SGADWMPNFIDLLQR
MAV_3986|M.avium_104 AGIAAVLGFSSADPRRGRVLFTDARTNPVLAARRRATQDMLRQGVLSEGW
Mflv_4630|M.gilvum_PYR-GCK APIRGLVSMINNDPRLGRILFVESATEPLLRE---LRSDMMTGFTDLVLR
Mvan_0313|M.vanbaalenii_PYR-1 APIRRLVSMIDNDPRLGRILFVESATEPLLRE---LRSELMAGFTDLVLR
MAB_2068c|M.abscessus_ATCC_199 APIKALVQLIENDPRMARILFVESGAESLLRQ---LRSELMTDFAELVLR
MMAR_3144|M.marinum_M APIKALVQMIENDPSMARILFVESGAEPLLRQ---LRSELMSEFAELVLR
: .: : ** .*:*: . :. * . :
MSMEG_5768|M.smegmatis_MC2_155 KLTRIADP-----VRQAMVATSLIGALTALFTAYLNDRLPATREQFIDFC
TH_1575|M.thermoresistible__bu KLTRITDP-----ALQAMVATGLIGALTALFTAYLDGRLAATREQFIDYC
Mb0848c|M.bovis_AF2122/97 KLSRIVDP-----VLQKLVATSLIGALTGLFTAYLNGRLGATRKQFIDYC
Rv0825c|M.tuberculosis_H37Rv KLSRIVDP-----VLQKLVATSLIGALTGLFTAYLNGRLGATRKQFIDYC
MUL_0446|M.ulcerans_Agy99 KLSQIADP-----VLQKLVATSLIGALTGLFTAYLNGQLGATRQQFIDYC
MAV_3986|M.avium_104 RLNPRSDP-----VAAEVAAAMYTGAMAELAQQWLAGHLGGDLDAVVDYA
Mflv_4630|M.gilvum_PYR-GCK EARLHLDIADSAVGVAHLASTLGVGGLFEVLRRWLDGELEFTTDELVQHC
Mvan_0313|M.vanbaalenii_PYR-1 EARLHLDIADSAVGVAHLASTLGVGGLFEVLRRRLDGELEFTTDELVQHC
MAB_2068c|M.abscessus_ATCC_199 EARLHLDIPSDVLQVADLAATYGVGGLFEILRRWIDGQLNLSTEMLIEHC
MMAR_3144|M.marinum_M EARLHLDIPSEVIQVADLAATYGVGGLFEILRRWIDGQLNLSTEVLIEHC
. * :.:: *.: : : ..* . .::..
MSMEG_5768|M.smegmatis_MC2_155 VDMLLGRVGSF------------------------
TH_1575|M.thermoresistible__bu VGILLNPVASY------------------------
Mb0848c|M.bovis_AF2122/97 VNMLLSTAATYAPHRERGESEHSIPAGPHN-----
Rv0825c|M.tuberculosis_H37Rv VNMLLSTAATYAPHRERGESEHSIPAGPHN-----
MUL_0446|M.ulcerans_Agy99 VDLLLGTAAAYAPHRDRGEAEHPVAARQHD-----
MAV_3986|M.avium_104 SKLVLR-----------------------------
Mflv_4630|M.gilvum_PYR-GCK AGFLGSLGSYVLLQNAVESATTKAKPQS-------
Mvan_0313|M.vanbaalenii_PYR-1 AGFLGSLGNYVLLQNTDQSATTEARPHR-------
MAB_2068c|M.abscessus_ATCC_199 AGFLGILGLYTLGQAPDQAAPPLAKAEETR-----
MMAR_3144|M.marinum_M AGFLGSLGLYTLGQKPDPAASHIQVDINSPAGHNR
::