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TRPLRADAARNRARVLEVAYDTFAAEGLTVPIDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVRRIAE RARTLLAVEGPGQALFVFFRDMVRSAAVDHGLVDALMNQGLDLEAVAPGVEAAFLSTLGDLLSAAQGAGT VRPDVDVAVVKALLVVCKVPQVFDSEVTERVTRVIEDGLRPLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0142 | - | - | 100% (184) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3060 | - | 3e-09 | 28.48% (158) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5272 | - | 1e-08 | 27.53% (178) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 3e-55 | 61.75% (183) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 3e-55 | 61.75% (183) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 3e-53 | 59.78% (184) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0647 | - | 1e-57 | 62.78% (180) | transcriptional regulator TetR |
| M. marinum M | MMAR_2062 | - | 2e-08 | 50.00% (54) | hypothetical protein MMAR_2062 |
| M. avium 104 | MAV_4593 | - | 7e-17 | 35.10% (151) | TetR family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0878 | - | 7e-50 | 57.30% (178) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_4110 | - | 1e-07 | 29.05% (179) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1500 | - | 1e-07 | 31.45% (159) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0763 | - | 6e-83 | 85.64% (181) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0142|M.gilvum_PYR-GCK --------------MTRPLRADAARNRAR-------VLEVAYDTFAAEGL
Mvan_0763|M.vanbaalenii_PYR-1 --------------MTRPLRADAARNRAR-------VLEVAYDTFAAEGL
Mb0068c|M.bovis_AF2122/97 -----------MAPTDRRVRADAARNRAR-------VLEVAYQTFAADGL
Rv0067c|M.tuberculosis_H37Rv -----------MAPTDRRVRADAARNRAR-------VLEVAYQTFAADGL
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRAR-------ILGVAYEAFATEGL
MAB_0647|M.abscessus_ATCC_1997 -----------MDQPARPLRADAARNRAR-------VLEVAYQTFAEEGL
MSMEG_0878|M.smegmatis_MC2_155 ----------------MSMRADAARNRAR-------VLEVAYEAFAQDGL
MAV_4593|M.avium_104 ----------------MVGRSDARRNRQR-------LLEAATAAFTAHGA
TH_4110|M.thermoresistible__bu ----------VTATDAAATGRAAARGRPRDPALDSAILDAALEIFVEQGI
MUL_1500|M.ulcerans_Agy99 ----------------MHLATDDRTARAR-------IRDEALRLFAERGP
MMAR_2062|M.marinum_M -------------MAIPEATTAAVPARER-------ILGAAYDLFSRRGI
* * : * * *
Mflv_0142|M.gilvum_PYR-GCK T-VPIDEIARRAGVGAGTVYRHFPTKEALVVAVAEDR--VRRIAERAR-T
Mvan_0763|M.vanbaalenii_PYR-1 G-VPIDEIARRAGVGAGTVYRHFPTKQALVVAVAEDR--VRRIVDHAR-T
Mb0068c|M.bovis_AF2122/97 S-VPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADR--MHRIIDKGH-A
Rv0067c|M.tuberculosis_H37Rv S-VPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADR--MHRIIDKGH-A
MLBr_00316|M.leprae_Br4923 S-VPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDR--MPHLVDDGY-V
MAB_0647|M.abscessus_ATCC_1997 G-VPIDEIARRAGVGAGTVYRHFPAKEDLYRAIAEDR--MGSVIDKGR-E
MSMEG_0878|M.smegmatis_MC2_155 A-VPIDEIARRAGVGAGTVYRHFPSKEDLYRAVVAER--IREIVDQGQ-A
MAV_4593|M.avium_104 S-VSLESIARDAGVGIGTLYRHFPNREALVEAVYRAE--LAEVAAAAA-Q
TH_4110|M.thermoresistible__bu SALSIEQVARRAGVGKPTIYRRWSDKEQLVADAIEHR--VSAELAWPTPA
MUL_1500|M.ulcerans_Agy99 DAVTMRDIATAAGVSPALLIRHYGSKDGLIEAVDNHV--IAIFEVLLTEA
MMAR_2062|M.marinum_M RAVGTDEVIERAGVARATLYRHFATKDDLVLAVLQRREELWTFGLIEQKS
: .: ***. : *:: :: * :
Mflv_0142|M.gilvum_PYR-GCK LLAVEGPGQALFVFFRDMVRSA--AVDHGLVDALMNQG-LDLEAVAPGVE
Mvan_0763|M.vanbaalenii_PYR-1 LLAAEGPGEALFVFLRDMVRSA--AADYGLVDALVGYG-LDLEVAAPGAE
Mb0068c|M.bovis_AF2122/97 LLKSKHPGDALFAFLRSMVLQWG-ATDRGLVEALAGVG-IEISSAAPEAE
Rv0067c|M.tuberculosis_H37Rv LLKSKHPGDALFAFLRSMVLQWG-ATDRGLVEALAGVG-IEISSAAPEAE
MLBr_00316|M.leprae_Br4923 LLKSAGPGEALFTYLRSLVLHWG-ATDRGLVDALAGAGGIDILGVAPDAE
MAB_0647|M.abscessus_ATCC_1997 LLAAVDPGEALFEFLRS-MMDWG-GTDQGLVDALSGAG-IDVQALIPHIE
MSMEG_0878|M.smegmatis_MC2_155 LLADGDPGEALFDYLRLMVLQCG-AADRGLVEALAGAG-IDVKTMVPDAE
MAV_4593|M.avium_104 LLQRHPPKAALRRWMDR-YATFV-ATKRGMAESLQAIF-ESGALVPSQTR
TH_4110|M.thermoresistible__bu EASVSDPYELVRRNISAAARTAADPAFRGLIAAIYGSAVTHPALLRTYWE
MUL_1500|M.ulcerans_Agy99 TRETEAVGLGQAAVGGLLDGLATHLPPDSAVPAYLSRMLISGGTAGPGLF
MMAR_2062|M.marinum_M RARGNTPEEQLLAIFDVLHEWFQ--SRDGYEGCSFINVLLELGADHPAGR
. . .
Mflv_0142|M.gilvum_PYR-GCK AAFLS---TLGDLLSAAQGAGTVRP--------------DVDVAVVKALL
Mvan_0763|M.vanbaalenii_PYR-1 AAFLA---TLGELLAAAQRAGTVRA--------------DVDVAVIKALL
Mb0068c|M.bovis_AF2122/97 ADFLD---LLTDLLRAAQRAGTVRP--------------DVDVLEVKTLL
Rv0067c|M.tuberculosis_H37Rv ADFLD---LLTDLLRAAQRAGTVRP--------------DVDVLEVKTLL
MLBr_00316|M.leprae_Br4923 DAFLT---ILSDLLYAAQYAGTART--------------DVGVREVKSIL
MAB_0647|M.abscessus_ATCC_1997 ESFYA---VLGDLLRAAQQAGTVRS--------------DVGVHEVKALL
MSMEG_0878|M.smegmatis_MC2_155 DEYME---MLGGLLRAAQRAGTVRG--------------DVTATDVKALL
MAV_4593|M.avium_104 DSIVG---AVETLLRAGADDASLRA--------------DVQADDVVSSL
TH_4110|M.thermoresistible__bu HYILPRRTAAIALLRRARDLGTVAA--------------DADLDVLVDML
MUL_1500|M.ulcerans_Agy99 ARLFR---LSQDTLNAMAAAGTASPGADPAVRAAFLLVNDLAVLTLRPRL
MMAR_2062|M.marinum_M ACIGHIDHVRGIVRERAVAAGLHDVED----------FAWSWHILMKGAI
. : :
Mflv_0142|M.gilvum_PYR-GCK VVCKVPQVFDSEVTERVTRVIEDGLRPLR------
Mvan_0763|M.vanbaalenii_PYR-1 VVCKVPQVYDGEVSERVVRVIEDGLRVRSSV----
Mb0068c|M.bovis_AF2122/97 VGCQAMQSYNAELAAKVTDVALDGLRANRK-----
Rv0067c|M.tuberculosis_H37Rv VGCQAMQSYNAELAAKVTDVALDGLRANRK-----
MLBr_00316|M.leprae_Br4923 VGCQAMEAYNSALAERVTDVVVDGLRAAR------
MAB_0647|M.abscessus_ATCC_1997 VGCQAMQSYNKDVSRQVTDVVFDGLRPRP------
MSMEG_0878|M.smegmatis_MC2_155 VGCQAMQAYDATAAEHLTGVVFDGLRVAPASVPSR
MAV_4593|M.avium_104 IGIFLVSGS-PEQTGRMLDLLVAGVTR--------
TH_4110|M.thermoresistible__bu AGAVTYRVLQPEPPSARQLRCYLEVAYRQVGLLP-
MUL_1500|M.ulcerans_Agy99 IEVLGVDPLTDAGMRRWAGEVFAVYRDGLVSD---
MMAR_2062|M.marinum_M ILAAVGDPDSARRAQRMAQVLIEQHRAAGAAAC--