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MAIPEATTAAVPARERILGAAYDLFSRRGIRAVGTDEVIERAGVARATLYRHFATKDDLVLAVLQRREEL WTFGLIEQKSRARGNTPEEQLLAIFDVLHEWFQSRDGYEGCSFINVLLELGADHPAGRACIGHIDHVRGI VRERAVAAGLHDVEDFAWSWHILMKGAIILAAVGDPDSARRAQRMAQVLIEQHRAAGAAAC
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2062 | - | - | 100% (201) | hypothetical protein MMAR_2062 |
| M. marinum M | MMAR_1350 | - | 1e-09 | 42.86% (77) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0287 | - | 1e-08 | 37.97% (79) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3198c | - | 5e-15 | 32.98% (188) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0059 | - | 3e-10 | 54.55% (55) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3173c | - | 5e-15 | 32.98% (188) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 3e-09 | 37.96% (108) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2458c | - | 7e-14 | 32.39% (176) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3517 | - | 7e-85 | 78.87% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6244 | - | 1e-23 | 39.23% (181) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3775 | - | 7e-20 | 36.67% (180) | PUTATIVE TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_2529 | - | 7e-10 | 42.86% (77) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4792 | - | 3e-17 | 33.71% (178) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2062|M.marinum_M --------------------------MAIPEATTAAVPARERILGAAYDL
MAV_3517|M.avium_104 --------------------------MTTPDAGSSGASARERVLTAAYEL
MSMEG_6244|M.smegmatis_MC2_155 --------------------------------MLDPDAARERVLAAAEEL
TH_3775|M.thermoresistible__bu --------------------------------MAETDD-KNRVLATATTL
Mvan_4792|M.vanbaalenii_PYR-1 ---------------------------------MPAEDPRQRAIDAAVEL
Mb3198c|M.bovis_AF2122/97 ---------------------MPPVTRTTEPPRRGGRGARQRILKAAAEL
Rv3173c|M.tuberculosis_H37Rv ---------------------MPPVTRTTEPPRRGGRGARQRILKAAAEL
MAB_2458c|M.abscessus_ATCC_199 ------------------MSSATVPTAADSARTARVLGPADRLLQTATDL
MLBr_00316|M.leprae_Br4923 -------------MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEA
MUL_2529|M.ulcerans_Agy99 MSDLAKAAQHRAVRSADRVRSTEGATPKARGNRLPRDERRGQLLIVASDV
Mflv_0059|M.gilvum_PYR-GCK --------------------------------MSGPDPASEQILDAAVVE
: : .*
MMAR_2062|M.marinum_M FSRRGIRAVGTDEVIERAGVARATLYRHFATKDDLVLAVLQRREELWTFG
MAV_3517|M.avium_104 FSRRGIRAVGTDEVIARAGVARATLYRHFATKNDLVLAVLQRREELWTYG
MSMEG_6244|M.smegmatis_MC2_155 FYARGIQAVGMDAVRTASGVSLKRLYQMFPSKEDLVVSFLQQRDSRWLGR
TH_3775|M.thermoresistible__bu FNERGVQAVGMDAIRDAAGISLKRLYSCFRSKADLVAAVLEQRDADVRRA
Mvan_4792|M.vanbaalenii_PYR-1 FHREGFGAVGIDRLTTSIGMSKRTLYKYFDSKDDLLLAVLDSCEGMALRD
Mb3198c|M.bovis_AF2122/97 FYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLR-QAAGE
Rv3173c|M.tuberculosis_H37Rv FYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLR-QAAGE
MAB_2458c|M.abscessus_ATCC_199 FATQGIRSVGIDQILREAGVAKASLYSSFGSKDALVVAYLEELDQRDRNR
MLBr_00316|M.leprae_Br4923 FATEGLSVP-IDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVD-
MUL_2529|M.ulcerans_Agy99 FVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLNRHVDKLVAG
Mflv_0059|M.gilvum_PYR-GCK FERHGFRRVALEDVARRAGVSRTTIYRRFANKDQLVGAVIERENVALFSD
* .* : : .:. :* * .* * :
MMAR_2062|M.marinum_M LIEQKSRARGNTPEEQLLAIFDVLHEWFQSRDGYEGCSFINVLLELG-AD
MAV_3517|M.avium_104 LIEEQSRLRGATPEEQLLAIFDVMDEWFRQGDRYEGCSFINVLLELG-PE
MSMEG_6244|M.smegmatis_MC2_155 LTAA-VEAHS-DPRERIPAVFDWLYSWF-SEPDYRGCAFINSFGELGGIS
TH_3775|M.thermoresistible__bu MTEY-VQSRAADPRDRILAVFDFLAHWF-AESDFRGCMFINTIGELGGTS
Mvan_4792|M.vanbaalenii_PYR-1 LPDE-DDDSS--PRDRILAVFDAQAKYC-TDPDFAGCFFVNIATEFRDPD
Mb3198c|M.bovis_AF2122/97 ADKM-PKASNATPRERLLALFDRPNR---GDGRMRGCPFHNAAVEAAGEM
Rv3173c|M.tuberculosis_H37Rv ADKM-PKASNATPRERLLALFDRPNR---GDGRMRGCPFHNAAVEAAGEM
MAB_2458c|M.abscessus_ATCC_199 WNAAVAAQRD--PIAKVLTFFDLAATAA-ESRNFRGCLYANAATEFPGLQ
MLBr_00316|M.leprae_Br4923 --DGYVLLKSAGPGEALFTYLRSLVLHWGATDRG---LVDALAGAGGIDI
MUL_2529|M.ulcerans_Agy99 VQQALRTTTD--NRGRLYAAVQAFFDFIEHDSQGYRLIFENDYVTEPEVA
Mflv_0059|M.gilvum_PYR-GCK IATELKQAGP--QSNYYVEAFTLSILKFRGHRVLHRMITEEPGLVLELAS
.
MMAR_2062|M.marinum_M HPAGRACIGHIDHVRGIVRE-RAVAAGLHDVEDFAWSWHILMKGAIILAA
MAV_3517|M.avium_104 HPAGKACIAHIDRVRDIVRR-RAVAAGLTDVEDFASSWHILMKGAIVLAA
MSMEG_6244|M.smegmatis_MC2_155 PAVADQARHHKREFHAYLT---ELVGAAGYPAELAAHLALLAEGAIVNSA
TH_3775|M.thermoresistible__bu TDVRRIARLHKTAVRDYLA---DLVAAAELPSELAEQLAILADGAIVAAT
Mvan_4792|M.vanbaalenii_PYR-1 HRAVRIAADHKAKLTQFLVR-QARLAGVAAPDDLAEQLTVLHTGAADYAL
Mb3198c|M.bovis_AF2122/97 PGVERIVHSHKRDYIKGLAR-LAREAGAAHPRSLGNQLAVLFEGAAALST
Rv3173c|M.tuberculosis_H37Rv PGVERIVHSHKRDYIKGLAR-LAREAGAAHPRSLGNQLAVLFEGAAALST
MAB_2458c|M.abscessus_ATCC_199 LEP---VRTHREWFRATVAA-LLREAGLARPDSIARQVQLLYDGALTGSK
MLBr_00316|M.leprae_Br4923 LGVAPDAEDAFLTILSDLLY-AAQYAGTARTDVGVREVKSILVGCQAMEA
MUL_2529|M.ulcerans_Agy99 AQVRVATESCIDAVFALISA-DSGLDPHRARMIAVALVSMSVDCARYWLD
Mflv_0059|M.gilvum_PYR-GCK LYYRAAIERMAEALRVIFPPGFAERIGADAVDELADTILRYATMVLLLPS
.
MMAR_2062|M.marinum_M VGDPDSARRAQRMAQVLIEQHR-----AAGAAAC
MAV_3517|M.avium_104 VGDLDAARRARRMARTLIEEHRPPLVSDTGEAV-
MSMEG_6244|M.smegmatis_MC2_155 IFGT-PDPATRAKQAALTLMQASGG---------
TH_3775|M.thermoresistible__bu IWGDGTDAAAAARRAAATLISAS-----------
Mvan_4792|M.vanbaalenii_PYR-1 LYGHYPDSTRTAVAALLTAAGL------------
Mb3198c|M.bovis_AF2122/97 SLDDAGPWAHARAAAEVLIDQATARPV-------
Rv3173c|M.tuberculosis_H37Rv SLDDAGPWAHARAAAEVLIDQATARPV-------
MAB_2458c|M.abscessus_ATCC_199 IDKSVVPITLARRLTRQLIG--------------
MLBr_00316|M.leprae_Br4923 YNSALAERVTDVVVDGLRAAR-------------
MUL_2529|M.ulcerans_Agy99 SDRPISKSDAIEGTVQFAWGGLSHVPLARS----
Mflv_0059|M.gilvum_PYR-GCK AQPLETADDIRAFARHHFLPSLPEALRSVPA---