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VTRPLRADAARNRARVLEVAYDTFAAEGLGVPIDEIARRAGVGAGTVYRHFPTKQALVVAVAEDRVRRIV DHARTLLAAEGPGEALFVFLRDMVRSAAADYGLVDALVGYGLDLEVAAPGAEAAFLATLGELLAAAQRAG TVRADVDVAVIKALLVVCKVPQVYDGEVSERVVRVIEDGLRVRSSV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0763 | - | - | 100% (186) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1492 | - | 2e-20 | 35.29% (187) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1060 | - | 2e-19 | 33.15% (181) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 2e-56 | 63.33% (180) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0142 | - | 5e-83 | 85.64% (181) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 2e-56 | 63.33% (180) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 8e-54 | 60.77% (181) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0647 | - | 5e-59 | 64.64% (181) | transcriptional regulator TetR |
| M. marinum M | MMAR_2062 | - | 3e-08 | 50.00% (54) | hypothetical protein MMAR_2062 |
| M. avium 104 | MAV_2463 | - | 1e-16 | 34.92% (189) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0878 | - | 2e-53 | 60.89% (179) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_4110 | - | 9e-08 | 31.64% (177) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3785 | - | 2e-06 | 27.56% (127) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0763|M.vanbaalenii_PYR-1 -----------MT---RPLRADAARNRAR-------VLEVAYDTFAAEGL
Mflv_0142|M.gilvum_PYR-GCK -----------MT---RPLRADAARNRAR-------VLEVAYDTFAAEGL
Mb0068c|M.bovis_AF2122/97 -----------MAPTDRRVRADAARNRAR-------VLEVAYQTFAADGL
Rv0067c|M.tuberculosis_H37Rv -----------MAPTDRRVRADAARNRAR-------VLEVAYQTFAADGL
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRAR-------ILGVAYEAFATEGL
MSMEG_0878|M.smegmatis_MC2_155 -----------MS-----MRADAARNRAR-------VLEVAYEAFAQDGL
MAB_0647|M.abscessus_ATCC_1997 -----------MDQPARPLRADAARNRAR-------VLEVAYQTFAEEGL
MAV_2463|M.avium_104 ----------MTAVEDRPLRSDAARNVER-------ILRAAREVYAELGP
TH_4110|M.thermoresistible__bu ----------VTATDAAATGRAAARGRPRDPALDSAILDAALEIFVEQGI
MUL_3785|M.ulcerans_Agy99 ----------MAASAPDEQTATPNRRSQQKSDRRLQLLSAAERLFAERGF
MMAR_2062|M.marinum_M -----------MAIPEATTAAVPAR--ER-------ILGAAYDLFSRRGI
. * : :* .* : *
Mvan_0763|M.vanbaalenii_PYR-1 GVP-IDEIARRAGVGAGTVYRHFPTKQALVVAVAEDR---VRRIVDHART
Mflv_0142|M.gilvum_PYR-GCK TVP-IDEIARRAGVGAGTVYRHFPTKEALVVAVAEDR---VRRIAERART
Mb0068c|M.bovis_AF2122/97 SVP-VDEIARRAGVGAGTVYRHFPTKEALFQAVIADR---MHRIIDKGHA
Rv0067c|M.tuberculosis_H37Rv SVP-VDEIARRAGVGAGTVYRHFPTKEALFQAVIADR---MHRIIDKGHA
MLBr_00316|M.leprae_Br4923 SVP-IDEIARRAGVGAGTVYRHFPTKEALCAAVIGDR---MPHLVDDGYV
MSMEG_0878|M.smegmatis_MC2_155 AVP-IDEIARRAGVGAGTVYRHFPSKEDLYRAVVAER---IREIVDQGQA
MAB_0647|M.abscessus_ATCC_1997 GVP-IDEIARRAGVGAGTVYRHFPAKEDLYRAIAEDR---MGSVIDKGRE
MAV_2463|M.avium_104 DAP-VEAVARRAGVGERTLYRRFPAKADLVRAALDQS---IAEDLTPVID
TH_4110|M.thermoresistible__bu SALSIEQVARRAGVGKPTIYRRWSDKEQLVADAIEHR---VSAELAWPTP
MUL_3785|M.ulcerans_Agy99 LAVRLEDIGAAAGISGPAIYRHFPNKESLLVELLVGI---SSRLLAGARQ
MMAR_2062|M.marinum_M RAVGTDEVIERAGVARATLYRHFATKDDLVLAVLQRREELWTFGLIEQKS
. : : **:. ::**::. * *
Mvan_0763|M.vanbaalenii_PYR-1 LLAAEGPGEALFVFLRDM-VRSAAA--DYGLVDALVGYG-LDLEVAAPGA
Mflv_0142|M.gilvum_PYR-GCK LLAVEGPGQALFVFFRDM-VRSAAV--DHGLVDALMNQG-LDLEAVAPGV
Mb0068c|M.bovis_AF2122/97 LLKSKHPGDALFAFLRSMVLQWGAT--DRGLVEALAGVG-IEISSAAPEA
Rv0067c|M.tuberculosis_H37Rv LLKSKHPGDALFAFLRSMVLQWGAT--DRGLVEALAGVG-IEISSAAPEA
MLBr_00316|M.leprae_Br4923 LLKSAGPGEALFTYLRSLVLHWGAT--DRGLVDALAGAGGIDILGVAPDA
MSMEG_0878|M.smegmatis_MC2_155 LLADGDPGEALFDYLRLMVLQCGAA--DRGLVEALAGAG-IDVKTMVPDA
MAB_0647|M.abscessus_ATCC_1997 LLAAVDPGEALFEFLRSM-MDWGGT--DQGLVDALSGAG-IDVQALIPHI
MAV_2463|M.avium_104 SARHAKDPLHGLTRLVEAAISLGAR--EQNLLAAAHRAG-----SLTSDI
TH_4110|M.thermoresistible__bu AEASVSDPYELVRRNISAAARTAADPAFRGLIAAIYGSAVTHPALLRTYW
MUL_3785|M.ulcerans_Agy99 VTTNSNDAAAALDGLIDFHLDFALG--EPDLIRIQDRDLGHLPAAAERQV
MMAR_2062|M.marinum_M RARGNTPEEQLLAIFDVLHEWFQSR---DGYEGCSFINVLLELGADHPAG
. .
Mvan_0763|M.vanbaalenii_PYR-1 EAAFL---ATLGELLAAAQRAGTVRADVDVAVIK---ALLVVCKVPQVYD
Mflv_0142|M.gilvum_PYR-GCK EAAFL---STLGDLLSAAQGAGTVRPDVDVAVVK---ALLVVCKVPQVFD
Mb0068c|M.bovis_AF2122/97 EADFL---DLLTDLLRAAQRAGTVRPDVDVLEVK---TLLVGCQAMQSYN
Rv0067c|M.tuberculosis_H37Rv EADFL---DLLTDLLRAAQRAGTVRPDVDVLEVK---TLLVGCQAMQSYN
MLBr_00316|M.leprae_Br4923 EDAFL---TILSDLLYAAQYAGTARTDVGVREVK---SILVGCQAMEAYN
MSMEG_0878|M.smegmatis_MC2_155 EDEYM---EMLGGLLRAAQRAGTVRGDVTATDVK---ALLVGCQAMQAYD
MAB_0647|M.abscessus_ATCC_1997 EESFY---AVLGDLLRAAQQAGTVRSDVGVHEVK---ALLVGCQAMQSYN
MAV_2463|M.avium_104 SVSLN---EALGELVREGQRAGRIRADLVADDLPRLVAMLYSVLSTMDAG
TH_4110|M.thermoresistible__bu EHYILPRRTAAIALLRRARDLGTVAADADLDVLV---DMLAGAVTYRVLQ
MUL_3785|M.ulcerans_Agy99 RKAQRQYVEIWVGVLR-QLDPGLAEADARLMAHAAFGLLNSTPHSMESAD
MMAR_2062|M.marinum_M RACIGHIDHVRGIVRERAVAAGLHDVEDFAWSWHILMKGAIILAAVGDPD
: * :
Mvan_0763|M.vanbaalenii_PYR-1 GE-VSERVVRVIEDGLRVRSSV-------------------
Mflv_0142|M.gilvum_PYR-GCK SE-VTERVTRVIEDGLRPLR---------------------
Mb0068c|M.bovis_AF2122/97 AE-LAAKVTDVALDGLRANRK--------------------
Rv0067c|M.tuberculosis_H37Rv AE-LAAKVTDVALDGLRANRK--------------------
MLBr_00316|M.leprae_Br4923 SA-LAERVTDVVVDGLRAAR---------------------
MSMEG_0878|M.smegmatis_MC2_155 AT-AAEHLTGVVFDGLRVAPASVPSR---------------
MAB_0647|M.abscessus_ATCC_1997 KD-VSRQVTDVVFDGLRPRP---------------------
MAV_2463|M.avium_104 SE-GWRRYVALVVDAISVDERRPLPPAAALRYASQPNSWPL
TH_4110|M.thermoresistible__bu PE-PPSARQLRCYLEVAYRQVGLLP----------------
MUL_3785|M.ulcerans_Agy99 TKSACAPHSRAVMRAMTVAALTVDVGA--------------
MMAR_2062|M.marinum_M SARRAQRMAQVLIEQHRAAGAAAC-----------------