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MSMRADAARNRARVLEVAYEAFAQDGLAVPIDEIARRAGVGAGTVYRHFPSKEDLYRAVVAERIREIVDQ GQALLADGDPGEALFDYLRLMVLQCGAADRGLVEALAGAGIDVKTMVPDAEDEYMEMLGGLLRAAQRAGT VRGDVTATDVKALLVGCQAMQAYDATAAEHLTGVVFDGLRVAPASVPSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0878 | - | - | 100% (189) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 1e-24 | 37.70% (183) | TetR-type regulator |
| M. smegmatis MC2 155 | MSMEG_1380 | - | 7e-21 | 35.98% (189) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 5e-64 | 66.29% (178) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0142 | - | 6e-50 | 57.30% (178) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 6e-64 | 66.29% (178) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 1e-60 | 64.64% (181) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0647 | - | 1e-63 | 64.64% (181) | transcriptional regulator TetR |
| M. marinum M | MMAR_2984 | - | 2e-08 | 32.09% (187) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2463 | - | 3e-19 | 36.54% (156) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4110 | - | 2e-09 | 29.27% (164) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3399 | - | 8e-07 | 45.00% (60) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0763 | - | 2e-53 | 60.89% (179) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0142|M.gilvum_PYR-GCK -----------------------------MT---RPLRADAARNRAR---
Mvan_0763|M.vanbaalenii_PYR-1 -----------------------------MT---RPLRADAARNRAR---
Mb0068c|M.bovis_AF2122/97 -----------------------------MAPTDRRVRADAARNRAR---
Rv0067c|M.tuberculosis_H37Rv -----------------------------MAPTDRRVRADAARNRAR---
MLBr_00316|M.leprae_Br4923 ------------------MSVPRSGLSVQMAQPARPLRADAARNRAR---
MSMEG_0878|M.smegmatis_MC2_155 -----------------------------MS-----MRADAARNRAR---
MAB_0647|M.abscessus_ATCC_1997 -----------------------------MDQPARPLRADAARNRAR---
MAV_2463|M.avium_104 ----------------------------MTAVEDRPLRSDAARNVER---
TH_4110|M.thermoresistible__bu ----------------------------VTATDAAATGRAAARGRPRDPA
MMAR_2984|M.marinum_M -----------------------------MTTSDRGAPAQANRSERRKRR
MUL_3399|M.ulcerans_Agy99 MLQYLNGLWSDLFQPSYSAGVSGVEGLGELPVSARQERGDAARNREL---
* *.
Mflv_0142|M.gilvum_PYR-GCK ----VLEVAYDTFAAEGLTVP-IDEIARRAGVGAGTVYRHFPTKEALVVA
Mvan_0763|M.vanbaalenii_PYR-1 ----VLEVAYDTFAAEGLGVP-IDEIARRAGVGAGTVYRHFPTKQALVVA
Mb0068c|M.bovis_AF2122/97 ----VLEVAYQTFAADGLSVP-VDEIARRAGVGAGTVYRHFPTKEALFQA
Rv0067c|M.tuberculosis_H37Rv ----VLEVAYQTFAADGLSVP-VDEIARRAGVGAGTVYRHFPTKEALFQA
MLBr_00316|M.leprae_Br4923 ----ILGVAYEAFATEGLSVP-IDEIARRAGVGAGTVYRHFPTKEALCAA
MSMEG_0878|M.smegmatis_MC2_155 ----VLEVAYEAFAQDGLAVP-IDEIARRAGVGAGTVYRHFPSKEDLYRA
MAB_0647|M.abscessus_ATCC_1997 ----VLEVAYQTFAEEGLGVP-IDEIARRAGVGAGTVYRHFPAKEDLYRA
MAV_2463|M.avium_104 ----ILRAAREVYAELGPDAP-VEAVARRAGVGERTLYRRFPAKADLVRA
TH_4110|M.thermoresistible__bu LDSAILDAALEIFVEQGISALSIEQVARRAGVGKPTIYRRWSDKEQLVAD
MMAR_2984|M.marinum_M TRTALLRAAQRLIAEGKLNVP-VLEITQAADVGMGSFYNHFDSKEQLFEA
MUL_3399|M.ulcerans_Agy99 ----LLQAARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMV
:* .* . . :: *.** :.:.:: : *
Mflv_0142|M.gilvum_PYR-GCK VAEDRVRRIAERARTLLAVEGPGQALFVFFRDM-VRSAAV--DHGLVDAL
Mvan_0763|M.vanbaalenii_PYR-1 VAEDRVRRIVDHARTLLAAEGPGEALFVFLRDM-VRSAAA--DYGLVDAL
Mb0068c|M.bovis_AF2122/97 VIADRMHRIIDKGHALLKSKHPGDALFAFLRSMVLQWGAT--DRGLVEAL
Rv0067c|M.tuberculosis_H37Rv VIADRMHRIIDKGHALLKSKHPGDALFAFLRSMVLQWGAT--DRGLVEAL
MLBr_00316|M.leprae_Br4923 VIGDRMPHLVDDGYVLLKSAGPGEALFTYLRSLVLHWGAT--DRGLVDAL
MSMEG_0878|M.smegmatis_MC2_155 VVAERIREIVDQGQALLADGDPGEALFDYLRLMVLQCGAA--DRGLVEAL
MAB_0647|M.abscessus_ATCC_1997 IAEDRMGSVIDKGRELLAAVDPGEALFEFLRSM-MDWGGT--DQGLVDAL
MAV_2463|M.avium_104 ALDQSIAEDLTPVIDSARHAKDPLHGLTRLVEAAISLGAR--EQNLLAAA
TH_4110|M.thermoresistible__bu AIEHRVSAELAWPTPAEASVSDPYELVRRNISAAARTAADPAFRGLIAAI
MMAR_2984|M.marinum_M AVADVLDAHGALLDRCTASIEDPAETFAASFRLTGRLFRRRPQESEILLA
MUL_3399|M.ulcerans_Agy99 LLDEDERASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSE
. . :
Mflv_0142|M.gilvum_PYR-GCK MNQG-LDLEAVAPGVEAAFL---STLGDLLSAAQGAGTVRPDVDVAVVK-
Mvan_0763|M.vanbaalenii_PYR-1 VGYG-LDLEVAAPGAEAAFL---ATLGELLAAAQRAGTVRADVDVAVIK-
Mb0068c|M.bovis_AF2122/97 AGVG-IEISSAAPEAEADFL---DLLTDLLRAAQRAGTVRPDVDVLEVK-
Rv0067c|M.tuberculosis_H37Rv AGVG-IEISSAAPEAEADFL---DLLTDLLRAAQRAGTVRPDVDVLEVK-
MLBr_00316|M.leprae_Br4923 AGAGGIDILGVAPDAEDAFL---TILSDLLYAAQYAGTARTDVGVREVK-
MSMEG_0878|M.smegmatis_MC2_155 AGAG-IDVKTMVPDAEDEYM---EMLGGLLRAAQRAGTVRGDVTATDVK-
MAB_0647|M.abscessus_ATCC_1997 SGAG-IDVQALIPHIEESFY---AVLGDLLRAAQQAGTVRSDVGVHEVK-
MAV_2463|M.avium_104 HRAG-----SLTSDISVSLN---EALGELVREGQRAGRIRADLVADDLPR
TH_4110|M.thermoresistible__bu YGSAVTHPALLRTYWEHYILPRRTAAIALLRRARDLGTVAADADLDVLV-
MMAR_2984|M.marinum_M NGAALLSSDRGLAPRALRDIKAASDAGRFRVEDPELALAMAGGALLGLG-
MUL_3399|M.ulcerans_Agy99 ANRNPLTRYGAAASVHRRHVR------VLLESADTTGDLDVQTDALLAL-
. : .
Mflv_0142|M.gilvum_PYR-GCK --ALLVVCKVPQVFDSEVTERVTRVIEDGLRPLR----------------
Mvan_0763|M.vanbaalenii_PYR-1 --ALLVVCKVPQVYDGEVSERVVRVIEDGLRVRSSV--------------
Mb0068c|M.bovis_AF2122/97 --TLLVGCQAMQSYNAELAAKVTDVALDGLRANRK---------------
Rv0067c|M.tuberculosis_H37Rv --TLLVGCQAMQSYNAELAAKVTDVALDGLRANRK---------------
MLBr_00316|M.leprae_Br4923 --SILVGCQAMEAYNSALAERVTDVVVDGLRAAR----------------
MSMEG_0878|M.smegmatis_MC2_155 --ALLVGCQAMQAYDATAAEHLTGVVFDGLRVAPASVPSR----------
MAB_0647|M.abscessus_ATCC_1997 --ALLVGCQAMQSYNKDVSRQVTDVVFDGLRPRP----------------
MAV_2463|M.avium_104 LVAMLYSVLSTMDAGSEGWRRYVALVVDAISVDERRPLPPAAALRYASQP
TH_4110|M.thermoresistible__bu --DMLAGAVTYRVLQPEPPSARQLRCYLEVAYRQVGLLP-----------
MMAR_2984|M.marinum_M --TLLRADPQRDGCAAADAVTEDLLRLFGLDAEQARAICRRPLPDLDGWD
MUL_3399|M.ulcerans_Agy99 ---LDVDYVEHQLNDRGHTLRTLGDAWEDLARKLCGR-------------
: :
Mflv_0142|M.gilvum_PYR-GCK ------
Mvan_0763|M.vanbaalenii_PYR-1 ------
Mb0068c|M.bovis_AF2122/97 ------
Rv0067c|M.tuberculosis_H37Rv ------
MLBr_00316|M.leprae_Br4923 ------
MSMEG_0878|M.smegmatis_MC2_155 ------
MAB_0647|M.abscessus_ATCC_1997 ------
MAV_2463|M.avium_104 NSWPL-
TH_4110|M.thermoresistible__bu ------
MMAR_2984|M.marinum_M QPDSAA
MUL_3399|M.ulcerans_Agy99 ------