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MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLSVPIDEIARRAGVGAGTVYRHFPTKEA LCAAVIGDRMPHLVDDGYVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAPDAEDA FLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYNSALAERVTDVVVDGLRAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00316 | - | - | 100% (200) | putative TetR/AcrR-family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 3e-06 | 36.90% (84) | putative TetR-family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 4e-06 | 43.10% (58) | putative TetR-family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 7e-68 | 68.25% (189) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0142 | - | 1e-52 | 59.78% (184) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 7e-68 | 68.25% (189) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0647 | - | 5e-64 | 65.59% (186) | transcriptional regulator TetR |
| M. marinum M | MMAR_2062 | - | 1e-08 | 37.96% (108) | hypothetical protein MMAR_2062 |
| M. avium 104 | MAV_4593 | - | 5e-17 | 33.90% (177) | TetR family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0878 | - | 5e-60 | 64.64% (181) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_2712 | - | 2e-08 | 39.47% (76) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3399 | - | 3e-06 | 40.62% (64) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0763 | - | 3e-53 | 60.77% (181) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0142|M.gilvum_PYR-GCK --------------------------------MTRPLRADAARNRARVLE
Mvan_0763|M.vanbaalenii_PYR-1 --------------------------------MTRPLRADAARNRARVLE
Mb0068c|M.bovis_AF2122/97 -----------------------------MAPTDRRVRADAARNRARVLE
Rv0067c|M.tuberculosis_H37Rv -----------------------------MAPTDRRVRADAARNRARVLE
MLBr_00316|M.leprae_Br4923 ------------------MSVPRSGLSVQMAQPARPLRADAARNRARILG
MAB_0647|M.abscessus_ATCC_1997 -----------------------------MDQPARPLRADAARNRARVLE
MSMEG_0878|M.smegmatis_MC2_155 ----------------------------------MSMRADAARNRARVLE
TH_2712|M.thermoresistible__bu ----VSLMSADELLPARPA--TDVAAP--TATTAPPEREDAARNRALLLD
MUL_3399|M.ulcerans_Agy99 MLQYLNGLWSDLFQPSYSAGVSGVEGLGELPVSARQERGDAARNRELLLQ
MAV_4593|M.avium_104 ----------------------------------MVGRSDARRNRQRLLE
MMAR_2062|M.marinum_M -------------------------------MAIPEATTAAVPARERILG
* * :*
Mflv_0142|M.gilvum_PYR-GCK VAYDTFAAEG-LTVPIDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVR
Mvan_0763|M.vanbaalenii_PYR-1 VAYDTFAAEG-LGVPIDEIARRAGVGAGTVYRHFPTKQALVVAVAEDRVR
Mb0068c|M.bovis_AF2122/97 VAYQTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH
Rv0067c|M.tuberculosis_H37Rv VAYQTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH
MLBr_00316|M.leprae_Br4923 VAYEAFATEG-LSVPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMP
MAB_0647|M.abscessus_ATCC_1997 VAYQTFAEEG-LGVPIDEIARRAGVGAGTVYRHFPAKEDLYRAIAEDRMG
MSMEG_0878|M.smegmatis_MC2_155 VAYEAFAQDG-LAVPIDEIARRAGVGAGTVYRHFPSKEDLYRAVVAERIR
TH_2712|M.thermoresistible__bu AARRLIAERGAEAVTMDDIAAAAGVGKGTLFRRFGSRAGLMLELLHDDET
MUL_3399|M.ulcerans_Agy99 AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER
MAV_4593|M.avium_104 AATAAFTAHG-ASVSLESIARDAGVGIGTLYRHFPNREALVEAVYRAELA
MMAR_2062|M.marinum_M AAYDLFSRRGIRAVGTDEVIERAGVARATLYRHFATKDDLVLAVLQRREE
.* .: * * :.: ***. .*::*:* : * :
Mflv_0142|M.gilvum_PYR-GCK RIAE---RARTLLAVEGPGQALFVFFRDM-VRSAAVD----HGLVDALMN
Mvan_0763|M.vanbaalenii_PYR-1 RIVD---HARTLLAAEGPGEALFVFLRDM-VRSAAAD----YGLVDALVG
Mb0068c|M.bovis_AF2122/97 RIID---KGHALLKSKHPGDALFAFLRSMVLQWGATD----RGLVEALAG
Rv0067c|M.tuberculosis_H37Rv RIID---KGHALLKSKHPGDALFAFLRSMVLQWGATD----RGLVEALAG
MLBr_00316|M.leprae_Br4923 HLVD---DGYVLLKSAGPGEALFTYLRSLVLHWGATD----RGLVDALAG
MAB_0647|M.abscessus_ATCC_1997 SVID---KGRELLAAVDPGEALFEFLRSM-MDWGGTD----QGLVDALSG
MSMEG_0878|M.smegmatis_MC2_155 EIVD---QGQALLADGDPGEALFDYLRLMVLQCGAAD----RGLVEALAG
TH_2712|M.thermoresistible__bu AFQQ---AFMFGPPPLGPGAEPLERLLAYGRRRLQFV----CDHHALLTD
MUL_3399|M.ulcerans_Agy99 ASQQ---AFLFGPPPLGPEAAPLDRLIAFGRERICFV----HAHHELLSE
MAV_4593|M.avium_104 EVAA---AAAQLLQRHPPKAALRRWMDRY-ATFVATK----RGMAESLQA
MMAR_2062|M.marinum_M LWTFGLIEQKSRARGNTPEEQLLAIFDVLHEWFQSRDGYEGCSFINVLLE
* : *
Mflv_0142|M.gilvum_PYR-GCK QG-LDLEAVAPGVEAAFLSTLGDLLSAAQGAGTVRPDVDVAVVKALLVV-
Mvan_0763|M.vanbaalenii_PYR-1 YG-LDLEVAAPGAEAAFLATLGELLAAAQRAGTVRADVDVAVIKALLVV-
Mb0068c|M.bovis_AF2122/97 VG-IEISSAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVG-
Rv0067c|M.tuberculosis_H37Rv VG-IEISSAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVG-
MLBr_00316|M.leprae_Br4923 AGGIDILGVAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVG-
MAB_0647|M.abscessus_ATCC_1997 AG-IDVQALIPHIEESFYAVLGDLLRAAQQAGTVRSDVGVHEVKALLVG-
MSMEG_0878|M.smegmatis_MC2_155 AG-IDVKTMVPDAEDEYMEMLGGLLRAAQRAGTVRGDVTATDVKALLVG-
TH_2712|M.thermoresistible__bu VS-REPQTRFGPPMTLHHTHIRSLLAAADADGDLDVQADALLALTDPDY-
MUL_3399|M.ulcerans_Agy99 AN-RNPLTRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDY-
MAV_4593|M.avium_104 IF-ESGALVPSQTRDSIVGAVETLLRAGADDASLRADVQADDVVSSLIG-
MMAR_2062|M.marinum_M LG---ADHPAGRACIGHIDHVRGIVRERAVAAGLHDVEDFAWSWHILMKG
: :: .
Mflv_0142|M.gilvum_PYR-GCK ----CKVPQVFDSEVTERVTRVIEDGLRPLR------
Mvan_0763|M.vanbaalenii_PYR-1 ----CKVPQVYDGEVSERVVRVIEDGLRVRSSV----
Mb0068c|M.bovis_AF2122/97 ----CQAMQSYNAELAAKVTDVALDGLRANRK-----
Rv0067c|M.tuberculosis_H37Rv ----CQAMQSYNAELAAKVTDVALDGLRANRK-----
MLBr_00316|M.leprae_Br4923 ----CQAMEAYNSALAERVTDVVVDGLRAAR------
MAB_0647|M.abscessus_ATCC_1997 ----CQAMQSYNKDVSRQVTDVVFDGLRPRP------
MSMEG_0878|M.smegmatis_MC2_155 ----CQAMQAYDATAAEHLTGVVFDGLRVAPASVPSR
TH_2712|M.thermoresistible__bu ----VRHQVTDRGVALDALADSWGDVARKLCRR----
MUL_3399|M.ulcerans_Agy99 ----VEHQLNDRGHTLRTLGDAWEDLARKLCGR----
MAV_4593|M.avium_104 ----IFLVSGSPEQTGRMLDLLVAGVTR---------
MMAR_2062|M.marinum_M AIILAAVGDPDSARRAQRMAQVLIEQHRAAGAAAC--
: *