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MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVPIILGWVLLTVLVNVVVPSLEVV SEQHSAPMTPMDAPSMKAMMRLGHNFREFDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHI QDFWGDRLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRTHEPAGVKAYVTGPAALSDDM HLIGNASLAKITMFTLGAIAVMLLLVYRSIVTTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANIL TMLAIAAGTDYGIFLVGRYQEARQAGEDREDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPWFNTMG APVAIGMLVVVLAGLTLGPAVVFVGSRFHLFESKRAANRGRLWRRVGTAVVRWPAPILALSGAIVLVGMV ALPGFKTSYNDRYYLPASAPSNLGEAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTV GIAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQVLIDTTERMYAVMRDL DTTTTDMARVTAETSTITDELRDHLAEFDDFWRPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEK FSELTEDIQHTAGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFDASKND DFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKV YLGGTAATFKDMADGEKYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDL FGIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVVTAAGLVFAFTMASML GSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIATLLGRWFWWPQVVHPRGDNARPRVAAPTH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3744 | mmpL4_1 | - | 100% (973) | transmembrane transport protein MmpL4_1 |
| M. marinum M | MMAR_0775 | - | 0.0 | 59.98% (957) | MmpL family transport protein |
| M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 59.51% (931) | transmembrane transport protein MmpL5_2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 60.71% (929) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 58.74% (921) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 60.82% (929) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 58.04% (920) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_3150 | - | 0.0 | 57.24% (926) | MmpL family protein |
| M. avium 104 | MAV_1755 | - | 0.0 | 81.79% (961) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_0576 | - | 0.0 | 69.43% (929) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 56.51% (922) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 0.0 | 99.49% (973) | transmembrane transport protein MmpL4_1 |
| M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 57.61% (939) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0458c|M.bovis_AF2122/97 ----------MSTKFANDSN----------TNARPEKPFIARMIHAFAVP
Rv0450c|M.tuberculosis_H37Rv ----------MSTKFANDSN----------TNARPEKPFIARMIHAFAVP
MLBr_02378|M.leprae_Br4923 ----------MTVKCANDLD----------THTKP--PFVARMIHRFAVP
Mflv_4418|M.gilvum_PYR-GCK -------------------------------MADAGRSGIGRIIRVLAVP
Mvan_1936|M.vanbaalenii_PYR-1 -------------------------------MADAGRSGIGRIIHLLAVP
TH_3260|M.thermoresistible__bu ----------MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLP
MAB_3150|M.abscessus_ATCC_1997 ----------MRHGSG---------------DHTARPPRIARLIRTLSIP
MMAR_3744|M.marinum_M MSESN--SGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVP
MUL_3688|M.ulcerans_Agy99 MSESN--SGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVP
MAV_1755|M.avium_104 MSDASNKTQPDLSAADTGPINVKGLS----KAERGHRPYLPHAIRIFAVP
MSMEG_0576|M.smegmatis_MC2_155 --------------------MIQGLH-----NRSDSRPLLPHALRVLAIP
. : :: :::*
Mb0458c|M.bovis_AF2122/97 IILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKE
Rv0450c|M.tuberculosis_H37Rv IILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKE
MLBr_02378|M.leprae_Br4923 IILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNE
Mflv_4418|M.gilvum_PYR-GCK IVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEE
Mvan_1936|M.vanbaalenii_PYR-1 IVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANFDE
TH_3260|M.thermoresistible__bu IIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDE
MAB_3150|M.abscessus_ATCC_1997 IILFWLGIAIVLNIVTPSLDEVGKAHSVSMSPKDAPSMIAMMHTGKVFGE
MMAR_3744|M.marinum_M IILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFRE
MUL_3688|M.ulcerans_Agy99 IILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFRE
MAV_1755|M.avium_104 IILGWLFVTVLVNVIVPTLEKVGEAHSAPMTPLDAPSMKAMMRLGHNFHE
MSMEG_0576|M.smegmatis_MC2_155 VILFWVAFAAVVNIIAPQLEIVGEEHSAPMAPEDAPSLTGMHRMGGNFQE
::: *: . .: * *: *.: ::. ::. :*** .* : * * *
Mb0458c|M.bovis_AF2122/97 GDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPL
Rv0450c|M.tuberculosis_H37Rv GDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPL
MLBr_02378|M.leprae_Br4923 GNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPL
Mflv_4418|M.gilvum_PYR-GCK FDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGDPL
Mvan_1936|M.vanbaalenii_PYR-1 FDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGDPL
TH_3260|M.thermoresistible__bu GSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPL
MAB_3150|M.abscessus_ATCC_1997 FDSDSSVMIVLEGQQELADEAHRFYDEIIKKLKADPTHIQHISDYWGDPL
MMAR_3744|M.marinum_M FDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRL
MUL_3688|M.ulcerans_Agy99 FDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRL
MAV_1755|M.avium_104 FDSNSTVMIVLEGQQPLGPDAHKYYDNLIRQLRQDPKHIQHIQDFWGDRL
MSMEG_0576|M.smegmatis_MC2_155 FDSNSTVMVVIEGQEPLGPDAHAYYDEIIRKLRQDPEHIQHIQDFWGDTL
.*:* *:::**:. *. *: :** :: .*. * ::: : * *.* *
Mb0458c|M.bovis_AF2122/97 TAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---PAPPG
Rv0450c|M.tuberculosis_H37Rv TAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---PAPPG
MLBr_02378|M.leprae_Br4923 TAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT---PAPPG
Mflv_4418|M.gilvum_PYR-GCK TASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRT---PAPPG
Mvan_1936|M.vanbaalenii_PYR-1 TASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQT---PAPPG
TH_3260|M.thermoresistible__bu TATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEG
MAB_3150|M.abscessus_ATCC_1997 TASGAQSADGKSAYVQVNLAGDQGTTLANESVDAVRKIIAET---PGPAG
MMAR_3744|M.marinum_M TAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRT---HEPAG
MUL_3688|M.ulcerans_Agy99 TAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRT---HEPAG
MAV_1755|M.avium_104 TAAGAQSADAKGAYVQVNLAGNQGTTLANESVDAVRKVIDEN---KAPPG
MSMEG_0576|M.smegmatis_MC2_155 TAAGAQSADGKAAYVMLNLAGEQGQTLANDGVQEVRQVIADT---PAPPG
**.*.** *.*.*** : * *:** *::.: **.:: * *
Mb0458c|M.bovis_AF2122/97 IKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVL
Rv0450c|M.tuberculosis_H37Rv IKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVL
MLBr_02378|M.leprae_Br4923 ITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVIL
Mflv_4418|M.gilvum_PYR-GCK IKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATMVL
Mvan_1936|M.vanbaalenii_PYR-1 LKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATMVL
TH_3260|M.thermoresistible__bu VQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLI
MAB_3150|M.abscessus_ATCC_1997 VQAYVTGGTAASADTGTAGNKSMQKTTLIAVGVVLLMLLLVYRSVITTIV
MMAR_3744|M.marinum_M VKAYVTGPAALSDDMHLIGNASLAKITMFTLGAIAVMLLLVYRSIVTTVI
MUL_3688|M.ulcerans_Agy99 VKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIVTTVI
MAV_1755|M.avium_104 VKAYVTGPAALSDDMHIIGNASLAKITLFTLGAIAIMLLLVYRSIVTTLV
MSMEG_0576|M.smegmatis_MC2_155 VQAYAAGPAALTDDLHVIGNASLGKITLFTLVAIAVMLLIVYRSIVTTLI
: *:.:* :. * *: *: :. .: **:*:**. * ::
Mb0458c|M.bovis_AF2122/97 LLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFI
Rv0450c|M.tuberculosis_H37Rv LLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFI
MLBr_02378|M.leprae_Br4923 LLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFI
Mflv_4418|M.gilvum_PYR-GCK ILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAIFA
Mvan_1936|M.vanbaalenii_PYR-1 ILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAIFA
TH_3260|M.thermoresistible__bu ALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFL
MAB_3150|M.abscessus_ATCC_1997 ALLIVGLELMAGQGVVATLGNLNVIGLSTYAVSMVTMLGIAAGTDYVIFL
MMAR_3744|M.marinum_M QLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGIFL
MUL_3688|M.ulcerans_Agy99 QLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGIFL
MAV_1755|M.avium_104 QLFMTFVALACSRGVVAVLAYHNAFGLTTFAANILTMLAIAAGTDYGIFL
MSMEG_0576|M.smegmatis_MC2_155 QLVLTGVGLLASRGLISVLATHDVFGLTTFAGNILTMLAIAAATDYGIFL
*. . :*::: *. :**:*:* .::. : ** ..** **
Mb0458c|M.bovis_AF2122/97 IGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPY
Rv0450c|M.tuberculosis_H37Rv IGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPY
MLBr_02378|M.leprae_Br4923 TGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPY
Mflv_4418|M.gilvum_PYR-GCK IGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPY
Mvan_1936|M.vanbaalenii_PYR-1 IGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPY
TH_3260|M.thermoresistible__bu IGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPY
MAB_3150|M.abscessus_ATCC_1997 LGRYHEARHRGQDREAAFYTAYSGVSHVILGSGLTIVGATLCLSLTRLPL
MMAR_3744|M.marinum_M VGRYQEARQAGEDREDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPW
MUL_3688|M.ulcerans_Agy99 VGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPW
MAV_1755|M.avium_104 IGRYQEALAAGEDRESAYYTTFKGVAPVVLGSGLTIAGATYCLSFSRLPW
MSMEG_0576|M.smegmatis_MC2_155 FGRYREARGAGEDPETAYYTTFKSVSPVIVGSGLTIAGATYCLSFARLPY
***:** . : *::* : .. *::.***** ** ***::*:*
Mb0458c|M.bovis_AF2122/97 FQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFGLFDPKRLLK-VRGWRR
Rv0450c|M.tuberculosis_H37Rv FQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFGLFDPKRLLK-VRGWRR
MLBr_02378|M.leprae_Br4923 FQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFGLFEPKRLIK-VRGWRR
Mflv_4418|M.gilvum_PYR-GCK FQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFGLFDPKRAIS-SRGWRR
Mvan_1936|M.vanbaalenii_PYR-1 FQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFGLFDPKRAIS-SRGWRR
TH_3260|M.thermoresistible__bu FQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFGLLEPKRAAR-VRFWRK
MAB_3150|M.abscessus_ATCC_1997 FRSMGVPCALVILVIVAAALTLAPAILALGSRFGLFEPKRKYD-EGGWRR
MMAR_3744|M.marinum_M FNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHLFESKRAANRGRLWRR
MUL_3688|M.ulcerans_Agy99 FNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHPFESKRAANRGRLWRR
MAV_1755|M.avium_104 FNTMGAPVAIGMLVVVLAGVTLGPAVVFVGSRFHFFE--RQAKRGRLWRR
MSMEG_0576|M.smegmatis_MC2_155 FSTMGAPVAIGMIVVVASSVTMGPAVLFLGSKVGLYEAKRAAK-GRFWRR
* ::* * *: :: : .:*:.**:: :.::. : * **:
Mb0458c|M.bovis_AF2122/97 VGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGY
Rv0450c|M.tuberculosis_H37Rv VGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGY
MLBr_02378|M.leprae_Br4923 IGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGF
Mflv_4418|M.gilvum_PYR-GCK IGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANVGY
Mvan_1936|M.vanbaalenii_PYR-1 IGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANVGY
TH_3260|M.thermoresistible__bu VGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGY
MAB_3150|M.abscessus_ATCC_1997 IGAAVVRWPGPILVVTCGIALVGLLTLPGYTPGYDDRQYMPDNVPSKVGY
MMAR_3744|M.marinum_M VGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNLGE
MUL_3688|M.ulcerans_Agy99 VGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNLGE
MAV_1755|M.avium_104 VGTAVVRWPAPVLAVSAAVVLVGMIALPSFHTSYNDRHYLPLSAPSNQGQ
MSMEG_0576|M.smegmatis_MC2_155 VGTAVVRWPAPILVASAFIVLIGVVAVPGYRPAYNDRWYLPDDAPVNIGF
:*. ***** *:: : :.::*::::*.: . *. * *:* * : *
Mb0458c|M.bovis_AF2122/97 AAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRV
Rv0450c|M.tuberculosis_H37Rv AAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRV
MLBr_02378|M.leprae_Br4923 AAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRV
Mflv_4418|M.gilvum_PYR-GCK AVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVARV
Mvan_1936|M.vanbaalenii_PYR-1 AVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVARV
TH_3260|M.thermoresistible__bu EAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRV
MAB_3150|M.abscessus_ATCC_1997 AAAERHFSPARMNPEMLMIEADHDLRDPSDMLVIDRIAKTAFHARGVGRV
MMAR_3744|M.marinum_M AAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGIAMI
MUL_3688|M.ulcerans_Agy99 AAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGIAMI
MAV_1755|M.avium_104 EAANRHFSEARMNPDLLMIESDHDMRNPADMLVLDRVAKNEMRTLGIAMV
MSMEG_0576|M.smegmatis_MC2_155 AAADRHFTQARMNPDILMVEADHDMRNPADMLVLDRVAKNVLRTQGIAMV
.*::** **::*::*::*::**:*:*:*:*:::::*: ::. *:. :
Mb0458c|M.bovis_AF2122/97 QAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMAT
Rv0450c|M.tuberculosis_H37Rv QAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMAT
MLBr_02378|M.leprae_Br4923 QAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAE
Mflv_4418|M.gilvum_PYR-GCK QTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAMQT
Mvan_1936|M.vanbaalenii_PYR-1 QTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAMQT
TH_3260|M.thermoresistible__bu QGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQL
MAB_3150|M.abscessus_ATCC_1997 QAITRPLGTPIEHSSIPFQIGLQGAGQIQNMKYMKDRMADMLTMANQMGI
MMAR_3744|M.marinum_M QDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQV
MUL_3688|M.ulcerans_Agy99 QDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQV
MAV_1755|M.avium_104 QDITRPLGIPIQHSSIPFQNSVQSQTTMQNMGFLKERMNDILKMADDLQT
MSMEG_0576|M.smegmatis_MC2_155 QSITRPLGIPIQHSSIPFQTAIQGQTSNLNLPFQRAQLDNQLKMVEATNQ
* **** * .:.*::*** . :. . : : : : .:
Mb0458c|M.bovis_AF2122/97 TIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPI
Rv0450c|M.tuberculosis_H37Rv TIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPI
MLBr_02378|M.leprae_Br4923 TIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPI
Mflv_4418|M.gilvum_PYR-GCK NVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPV
Mvan_1936|M.vanbaalenii_PYR-1 NVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVRPV
TH_3260|M.thermoresistible__bu MIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPI
MAB_3150|M.abscessus_ATCC_1997 LIGTMERVYGMMRELTDIMHDMTGQMKEMQGKMHDMRDLMYTFDDFFRPI
MMAR_3744|M.marinum_M LIDTTERMYAVMRDLDTTTTDMARVTAETSTITDELRDHLAEFDDFWRPM
MUL_3688|M.ulcerans_Agy99 LIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAEFDDFWRPM
MAV_1755|M.avium_104 QIDTTQRQYEVSMDLANAADDSAKTTAVTSQITDSLRDHIADFDDTFRPI
MSMEG_0576|M.smegmatis_MC2_155 SIAIMEKQYELSLRQTKLTQDSAEKSRELLEVTKQLRDNIANFDDQFRPL
: : : .:** : :** **:
Mb0458c|M.bovis_AF2122/97 RSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLM
Rv0450c|M.tuberculosis_H37Rv RSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLM
MLBr_02378|M.leprae_Br4923 RSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLM
Mflv_4418|M.gilvum_PYR-GCK RNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDELM
Mvan_1936|M.vanbaalenii_PYR-1 RNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDALM
TH_3260|M.thermoresistible__bu RNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLM
MAB_3150|M.abscessus_ATCC_1997 RNYFYWEKHCADIPICWASRTVFDALDGVDQITEDMDGMVVNVDKIDVLM
MMAR_3744|M.marinum_M RSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQHTAGLT
MUL_3688|M.ulcerans_Agy99 RSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQRTAGLT
MAV_1755|M.avium_104 RTYFYWEKHCYDIPVCIGLRSLFDTFDGFDQLAEQFHYLTTDIAHTAKAS
MSMEG_0576|M.smegmatis_MC2_155 RNYFYWEPHCFDIPMCAAARSLFDSLDTVDELTDRTSAVQVNTDELADLA
*.***** ** .:*:* *::**::* .: : : : . .
Mb0458c|M.bovis_AF2122/97 PQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFD
Rv0450c|M.tuberculosis_H37Rv PQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFD
MLBr_02378|M.leprae_Br4923 PQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFD
Mflv_4418|M.gilvum_PYR-GCK PQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFD
Mvan_1936|M.vanbaalenii_PYR-1 PQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEAFD
TH_3260|M.thermoresistible__bu PQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFD
MAB_3150|M.abscessus_ATCC_1997 PRVLAEFPPMIAIMKTMHGSLLTMHSTMAGIMNQMDESTKNSTLMGKYFD
MMAR_3744|M.marinum_M SQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFD
MUL_3688|M.ulcerans_Agy99 SQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFD
MAV_1755|M.avium_104 RDLTALFPTLITTLKTTRGITLTLYQTFKAMIDQMEAMSNTAVVMGQSFD
MSMEG_0576|M.smegmatis_MC2_155 PQLTALLPQTIASMKTSRDLSLASYNSQKALLDQMQAMNDTALAMGQSFD
: :* : :.. : * : . :* . : **: **
Mb0458c|M.bovis_AF2122/97 AAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEG
Rv0450c|M.tuberculosis_H37Rv AAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEG
MLBr_02378|M.leprae_Br4923 TAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAG
Mflv_4418|M.gilvum_PYR-GCK DSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATVEG
Mvan_1936|M.vanbaalenii_PYR-1 DSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATVEG
TH_3260|M.thermoresistible__bu QARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEG
MAB_3150|M.abscessus_ATCC_1997 EAKNDDSFYLPPEVFDNPDFKRGLKMFLSPDGKAVRMTVSHQGNPASVQG
MMAR_3744|M.marinum_M ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEG
MUL_3688|M.ulcerans_Agy99 ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEG
MAV_1755|M.avium_104 ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMSPEG
MSMEG_0576|M.smegmatis_MC2_155 EAKNDDFFYLPPEAFQNPDFERGLKMFLSPDGKSARMFITHQSDPATPEG
: *** ******.*.* **: .:. *:*.**::.*: : *..:* : *
Mb0458c|M.bovis_AF2122/97 IKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAI
Rv0450c|M.tuberculosis_H37Rv IKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAI
MLBr_02378|M.leprae_Br4923 IASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGI
Mflv_4418|M.gilvum_PYR-GCK ISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGI
Mvan_1936|M.vanbaalenii_PYR-1 ISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIAGI
TH_3260|M.thermoresistible__bu LAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAI
MAB_3150|M.abscessus_ATCC_1997 IETVGNIREAVADAIKGTPLENAKVYMGGTAATNRDLQEGAKYDLILAGI
MMAR_3744|M.marinum_M ISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMIAVV
MUL_3688|M.ulcerans_Agy99 ISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMIAVV
MAV_1755|M.avium_104 IKRVDAERTAAQEGLKQSSLSDARVYLGGTAATFKDMADGEKYDLMIAVV
MSMEG_0576|M.smegmatis_MC2_155 IARVNAERTAAQEGLKMSSLSDAKIFLGGTAATYKDMSDGARYDLMIAVV
: : : *. :.:* :.*..: :::.****. :*: :* :**::* :
Mb0458c|M.bovis_AF2122/97 SSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHL
Rv0450c|M.tuberculosis_H37Rv SSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHL
MLBr_02378|M.leprae_Br4923 SSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIEL
Mflv_4418|M.gilvum_PYR-GCK AAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL
Mvan_1936|M.vanbaalenii_PYR-1 AAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL
TH_3260|M.thermoresistible__bu AAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEM
MAB_3150|M.abscessus_ATCC_1997 ASLCLIFIIMLLVTGSVVAALVIVGTVAVSLGASVGVSVLIWQDLLGMDL
MMAR_3744|M.marinum_M SALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIKI
MUL_3688|M.ulcerans_Agy99 SALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIKI
MAV_1755|M.avium_104 SALTLIFMIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIRI
MSMEG_0576|M.smegmatis_MC2_155 SALTLIFMIMLILTRSAVAALVIVGTAASSIAASFGISVLLWQDLFGVEV
::: ***:***::* : :** *****. *:.**.*:***:** :..: :
Mb0458c|M.bovis_AF2122/97 HWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVV
Rv0450c|M.tuberculosis_H37Rv HWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVV
MLBr_02378|M.leprae_Br4923 HYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVV
Mflv_4418|M.gilvum_PYR-GCK HWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVV
Mvan_1936|M.vanbaalenii_PYR-1 HWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSVV
TH_3260|M.thermoresistible__bu HWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVV
MAB_3150|M.abscessus_ATCC_1997 HWFVVPLSVIILLAVGSDYNLLLIARFKEELHGGLKTGFIRAMGGSGKVV
MMAR_3744|M.marinum_M HWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVV
MUL_3688|M.ulcerans_Agy99 HWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVV
MAV_1755|M.avium_104 HWIVAALSVIILLAVGSDYNLLLVSRFREEIHGGLKTGIIRSMAGTGGVV
MSMEG_0576|M.smegmatis_MC2_155 HWLVMLMSVIILLAVGSDYNLLLVSRFKDEIHAGLKTGIIRSMAGTGGVV
*::* :::*:*****:*****:::*:::*: .**:**:**:*.*:* **
Mb0458c|M.bovis_AF2122/97 TNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAA
Rv0450c|M.tuberculosis_H37Rv TNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAA
MLBr_02378|M.leprae_Br4923 TNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAA
Mflv_4418|M.gilvum_PYR-GCK TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA
Mvan_1936|M.vanbaalenii_PYR-1 TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA
TH_3260|M.thermoresistible__bu TAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIAT
MAB_3150|M.abscessus_ATCC_1997 TNAGLVFAFTMCAMVVSDLRIVGQLGTTIGLGLLFDTLIVRSFMMPSIAA
MMAR_3744|M.marinum_M TAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT
MUL_3688|M.ulcerans_Agy99 TAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT
MAV_1755|M.avium_104 TAAGLVFAFTMAAMLGSELRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT
MSMEG_0576|M.smegmatis_MC2_155 TSAGLVFAATMAAMLGSELVVLAQMGSTIAIGLLLDTLIVRSLLMPSIAT
* *****. ** : *:* ::.*.*:*: :***:**::**::: *::*:
Mb0458c|M.bovis_AF2122/97 LLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-
Rv0450c|M.tuberculosis_H37Rv LLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-
MLBr_02378|M.leprae_Br4923 LLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD-----
Mflv_4418|M.gilvum_PYR-GCK LLGRWFWWPQKFRSAASERRLARIGVQ-PATAGR--------
Mvan_1936|M.vanbaalenii_PYR-1 LLGRWFWWPQKVRSHASQRRLAALNH----------------
TH_3260|M.thermoresistible__bu LLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV-----
MAB_3150|M.abscessus_ATCC_1997 LLGRWFWWPLRVRTHGTAGV----------------------
MMAR_3744|M.marinum_M LLGRWFWWPQVVHPRGDNARPRVAAPTH--------------
MUL_3688|M.ulcerans_Agy99 LLGRWFWWPQVVHPRGDNARPRVAAPTH--------------
MAV_1755|M.avium_104 LLGRWFWWPMVVHPRGDNARRPVPASS---------------
MSMEG_0576|M.smegmatis_MC2_155 LLGRWFWWPQVVYPRGDNHFRRPTAVSRGTGDEDTAALPVPS
*********