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STDGTHRSSRLVNFLIVAAWIAVAVIANLAVVLAPGKSSDAGSALLSPDSTASAASSRIGQAFPGTGTNA VAYLVVDGPDTLGPADQSYYDAAVNALRADSRHIGSVLDWWSDPLTVPLGTGSDGHSAMAMVWLVGQAGS TQARESLQAAQSVVHNLPASARLRARVVGPTTSSSVPAHMTVWQGAVIVLATAVIAVLLLLWARRSLVAA AVVLLTAGLSLAVAWPLAAALRAIPGQNISVFTVFSATLAAVLTIGAIAASTMLVARPGHAPGATAAQPL GRSASRDNLAALAMPAAGVAILTAPLLLARTPALHGVGVAALGVVVALAASLTLLPALIGLTGPSRLSSS RPVGARRTLPVSLPRTAVVAALVLAVCAVPVIGMQWGIGDGPVNPAAGGTKRALPWQPLPDVVMLEAKHD LSDPAGLIAIDQVSHRLMEIPGVRRVESAAWPAGVPWTDASLTAAAGKLSDELDRGAGSFMPQVRAIKTL GSIVDQMSGAVDELDRSVTAGLAGAAQIQQNVDLLISGTKNIKGVTVELSGYLDPVRGWMGDVPNCPGDM LCVAAGKVIDPVDRVVDDVKLLTDGADRIAAVSRKTVGAFSSAPHVVAQMRSALAQLQSFVPNLETTIEN TLPQLVQVSAFLKNLRLDFANTGQGDFYLSGKALADPSYQQVRQSMFSADGTATRLLVFSEGNPGLDASA RAQQLEAAAGKAMKYGSLEDAEITVNGAAQVATDVRGSLTHDAVLLAAMMLAAVVLVSMWRGALTAVVMA VGLLAAYLAALGISTALWQYLAGREIPAAVPLVSFAILAACGLPYLLDRTATPISTEAPITSDAQPADTA ALRNAGAPLAALTAVFGLGLVLVSAGSLGALSQIGTVVLFGVAALTVLARVCIPAAMQDRADRTTVATEP VAQPD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2007 | mmpL7 | - | 100% (916) | transmembrane transport protein MmpL7 |
| M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 1e-59 | 23.45% (917) | transmembrane transport protein MmpL4_1 |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 6e-58 | 23.16% (911) | transmembrane transport protein, MmpL5 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2967 | mmpL7 | 0.0 | 58.80% (898) | transmembrane transport protein MmpL7 |
| M. gilvum PYR-GCK | Mflv_2705 | - | 5e-63 | 25.65% (928) | transport protein |
| M. tuberculosis H37Rv | Rv2942 | mmpL7 | 0.0 | 58.80% (898) | transmembrane transport protein MmpL7 |
| M. leprae Br4923 | MLBr_00137 | mmpL7 | 0.0 | 55.68% (898) | hypothetical protein MLBr_00137 |
| M. abscessus ATCC 19977 | MAB_1520c | - | 1e-118 | 30.18% (921) | MmpL family membrane protein |
| M. marinum M | MMAR_1764 | mmpL7 | 0.0 | 99.45% (916) | transmembrane transport protein MmpL7 |
| M. avium 104 | MAV_5284 | - | 1e-110 | 30.85% (901) | membrane protein, MmpL family protein |
| M. smegmatis MC2 155 | MSMEG_0382 | - | 2e-68 | 25.11% (932) | putative transport protein |
| M. thermoresistible (build 8) | TH_3056 | - | 4e-70 | 25.03% (927) | PUTATIVE Mmp14a protein |
| M. vanbaalenii PYR-1 | Mvan_3833 | - | 4e-63 | 24.03% (928) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0382|M.smegmatis_MC2_155 -------------------MSTEQSGTEKARRPFFARAVRTLSPFIIVGW
TH_3056|M.thermoresistible__bu -------------------MSVLDRVGVEPRRPRVASFIRRYSVLIILGW
Mflv_2705|M.gilvum_PYR-GCK -------------------MSSSRDRAALREPRSVARWIRRLAVPIILGW
Mvan_3833|M.vanbaalenii_PYR-1 -------------------MRAHADR-DLRDPTPVARWIRRLAIPIILGW
MAB_1520c|M.abscessus_ATCC_199 ---------------------------MWD---AIARFSSRYAVLIIGLW
MAV_5284|M.avium_104 ---------------------------MPDRPGILGRLTGRYALLVVGLW
MUL_2007|M.ulcerans_Agy99 -----------------------------MSTDGTHRSSRLVNFLIVAAW
MMAR_1764|M.marinum_M -----------------------------MSTDGTHRSSRLVNFLIVAAW
Mb2967|M.bovis_AF2122/97 MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAW
Rv2942|M.tuberculosis_H37Rv MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAW
MLBr_00137|M.leprae_Br4923 -----------------------------MSTDDSHRSLRLANLLVITAW
:: *
MSMEG_0382|M.smegmatis_MC2_155 LAVILVTTLAAVGGDWSAAIPALERVGEKNSVSLMPQDAPSAKAMKHMGQ
TH_3056|M.thermoresistible__bu VALTVLAT---------VAVPPLEAVEREKSLSLIPYDAPAFAAMHRMGE
Mflv_2705|M.gilvum_PYR-GCK LLLAVALN---------ALVPQLEVVAAKNAVSMSPSNAPSMQAMADMGR
Mvan_3833|M.vanbaalenii_PYR-1 VLLVAALN---------LLVPQLEVVAAQNAVSMSPSDAPAMQAMSDMGR
MAB_1520c|M.abscessus_ATCC_199 VLLAGAGN---------LLVPQVESTAHNHARGFLPQDAPVNAAGAVMGR
MAV_5284|M.avium_104 VLAAAVAN---------VAVPQLERVVDSHARSFMPPSAPSAVAAARAAQ
MUL_2007|M.ulcerans_Agy99 IAVAVIAN---------LAVVLAPGKSSDAGSALLSPDSTASAASSRIGQ
MMAR_1764|M.marinum_M IAVAVIAN---------LAVVLAPGKSSDAGSALLSPDSTASAASSRIGQ
Mb2967|M.bovis_AF2122/97 VAAAVIAN---------LLLTFTQAEPHDTSPALLPQDAKTAAATSRIAQ
Rv2942|M.tuberculosis_H37Rv VAAAVIAN---------LLLTFTQAEPHDTSPALLPQDAKTAAATSRIAQ
MLBr_00137|M.leprae_Br4923 ITAVVIAN---------LIFTLTQAKLRDKNSVLLPQDTMTVTTTNQIAQ
: . . . : . .: : ..
MSMEG_0382|M.smegmatis_MC2_155 KFEESDSDSFAMIVLEGQ--EPLGPDALDYYTGLISELRNDSKHVEHVQD
TH_3056|M.thermoresistible__bu LFDEPDSESIAIIVLEGQ--EPLGLEAHEYYDQLISQLREHPQYVQHIRD
Mflv_2705|M.gilvum_PYR-GCK LFEESDSDSIALIVLESETDQPLGDDAHEYYDGLIAALLADTENVRNIQD
Mvan_3833|M.vanbaalenii_PYR-1 LFGESDSDSIAMVVLEGE--QPLGDDAHAYYDQLIEKLEAAPDHVRNIQD
MAB_1520c|M.abscessus_ATCC_199 QFQDGAGNNLNYLVLESD--HKLGPVEHQYHDRLLTTLRADTTHLDSAMD
MAV_5284|M.avium_104 LFDQTPSNNFVYVVLERN--QRLGAGDRQFYDALAAALGSDHRHVYAVTD
MUL_2007|M.ulcerans_Agy99 AFPGTGTNAVAYLVVDGP--DTLGPADQSYYDAAVNALRADSRHIGSVLD
MMAR_1764|M.marinum_M AFPGTGTNAVAYLVVDGP--DTLGPADQSYYDAAVNALRADSRHIGSVLD
Mb2967|M.bovis_AF2122/97 AFPGTGSNAIAYLVVEGG--STLEPQDQPYYDAAVGALRADTRHVGSVLD
Rv2942|M.tuberculosis_H37Rv AFPGTGSNAIAYLVVEGG--STLEPQDQPYYDAAVGALRADTRHVGSVLD
MLBr_00137|M.leprae_Br4923 AFPGTGTNAIAYLVVEGN--RTLEPEDQPYYDSAVNALRADTHDVGSVLD
* : . :*:: * :: * : *
MSMEG_0382|M.smegmatis_MC2_155 LWGDRLTASSAQSADGKAAYVQLNLAGNQGTPLGDESVAAVRDLVARTPA
TH_3056|M.thermoresistible__bu FWGDPLTAGAAQSDDGKAAFVQVNLVGRFGQAKVNEAVRAVQEIVERTPA
Mflv_2705|M.gilvum_PYR-GCK TWGDPLTEAAAQSSDGRAAYATLNLAGNMGETESNEAVAAVRDIVANSPP
Mvan_3833|M.vanbaalenii_PYR-1 MWGDPLTEAAAQSTDGHAAYVALNLAGNMGETKSNESVAAVRDIVADSPP
MAB_1520c|M.abscessus_ATCC_199 LWADPLTAEGALSPDGKAVYTMLRVNGELGAAKANDALAAVRKIVADQPA
MAV_5284|M.avium_104 LWSQPATAAGAQSTDGQAVSVMVRLAGMLGTAQARDSVNAVRATAQKLGP
MUL_2007|M.ulcerans_Agy99 WWSDPLTVPLGTGSDGHSAMAMVWLVGQAGSTQARESLQAAQSVVHNLPA
MMAR_1764|M.marinum_M WWSDPLTVPLGTGSDGHSAMAMVWLVGQAGSTQARESLQAAQSVVHNLPA
Mb2967|M.bovis_AF2122/97 WWSDPVTAPLGTSPDGRSATAMVWLRGEAGTTQAAESLDAVRSVLRQLPP
Rv2942|M.tuberculosis_H37Rv WWSDPVTAPLGTSPDGRSATAMVWLRGEAGTTQAAESLDAVRSVLRQLPP
MLBr_00137|M.leprae_Br4923 WWSDPLTAPLGTSPDSRSAIALIWLQGEAGTTRARASLGAIRSVVRQLPP
*.: * . . *.::. . : : * * . :: * : .
MSMEG_0382|M.smegmatis_MC2_155 PEGVSVYVTGAAPLVSDMQHSGNRSILKITAVTVVIIFAMLLMVYRSVIT
TH_3056|M.thermoresistible__bu PEGVETFVTGPAALGADAGDSGTATVILITLVTVAVIFLMLLFFFRSFLT
Mflv_2705|M.gilvum_PYR-GCK PPGVTVHVTGPAALIADVNIAGERSMALVLLVTFVVIIVLLLFFYRSIST
Mvan_3833|M.vanbaalenii_PYR-1 PPGVQVHVTGPAALTADVNIAGESSMALILLVTFVVIIVLLLFFYRSITT
MAB_1520c|M.abscessus_ATCC_199 PPGTQAWVTGPGATIADELTAIDTQMLMITGVTVVLIAVLLFVVYRSVIT
MAV_5284|M.avium_104 PAGLQVHVTGPGATIVDEFSAIDRQMLGITAATIGLILLLLLVVYRSPVA
MUL_2007|M.ulcerans_Agy99 SARLRARVVGPTTSSSVPAHMTVWQGAVIVLATAVIAVLLLLWARRSLVA
MMAR_1764|M.marinum_M SAGLRARVVGPTTSSSVPAHMTVWQGAVIVLATAVIAVLLLLWARRSLVA
Mb2967|M.bovis_AF2122/97 SEGLRASIVVPAITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRA
Rv2942|M.tuberculosis_H37Rv SEGLRASIVVPAITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRA
MLBr_00137|M.leprae_Br4923 SEELRARIVVPATTNNMPMEMTAWQGMAIVTAAAVIAILFLLRARQAIRI
. . :. . : .: : :*: :
MSMEG_0382|M.smegmatis_MC2_155 VILLLIMVGFEVAAARGIVAFLG---ANEVFVLSTFAVNMLVFLAIAAGT
TH_3056|M.thermoresistible__bu VIVLLLTVAVELQVARGLVAYLG---LQGWVGLTTYVVNLLVSVGIAAGT
Mflv_2705|M.gilvum_PYR-GCK VLLLLVVVGIQLLVARGVVAALA---HVGVIGLSTYATNLLISLAVAAGT
Mvan_3833|M.vanbaalenii_PYR-1 VVLLLIMVGVQMSVARGVVAALG---HFQVIGLSTFAVNLLISLAVAAGT
MAB_1520c|M.abscessus_ATCC_199 AAIPLMTVGLGLAVARSIVAFLG---ERDLIEVSIFSVSLLAALVLGAAT
MAV_5284|M.avium_104 AAIPLISVGLALALARAVVAALG---QANVVEVSLFSVALMAAMTLGAGT
MUL_2007|M.ulcerans_Agy99 AAVVLLTAGLSLAVAWPLAAALRAIPGQNISVFTVFSATLAAVLTIGAIA
MMAR_1764|M.marinum_M AAVVLLTAGLSLAVAWPLAAALRAIPGQNISVFTVFSATLAAVLTIGAIA
Mb2967|M.bovis_AF2122/97 AAIVLLTADLSLAVAWPLAAVVR---GHDWGTDSVFSWTLAAVLTIGTIT
Rv2942|M.tuberculosis_H37Rv AAIVLLTADLSLAVAWPLAAVVR---GHDWGTDSVFSWTLAAVLTIGTIT
MLBr_00137|M.leprae_Br4923 VVIMLLTADFSLAAAWPLAAVVQ---RQTGGTVSVFSWNLAAVLTIGTIT
. : *: . . : * :.* : : : : : :.: :
MSMEG_0382|M.smegmatis_MC2_155 DYGIFFFGRYQEARAAGEDRETAYYSMYRGVTPVVMASGLTIAGAIFCLT
TH_3056|M.thermoresistible__bu DYGIFFFGRYQEAREAGEDRDSAYFTTYRSVAKVVLASGLTIAGAIACLS
Mflv_2705|M.gilvum_PYR-GCK DYAIFLVGRYQEARASGADHEEAYYEMFHGTAHVVLGSGLTIAGAMLCLS
Mvan_3833|M.vanbaalenii_PYR-1 DYAIFLVGRYQEARASGADPEAAYYEMFGGTAHVVLGSGLTIAGAMYCLS
MAB_1520c|M.abscessus_ATCC_199 DYGIFLLGRYHEQRRSGVDHEQALVIANRSVAPVIAASGLTIAAALSCLL
MAV_5284|M.avium_104 DYAIFLVGRYHEARRGGVAPAQALTVAYRSIAPVVIGSALTVSVALACLV
MUL_2007|M.ulcerans_Agy99 ASTMLVARPGHAPGATAAQP--LGRSASRDNLAALAMPAAGVAILTAPLL
MMAR_1764|M.marinum_M ASTMLVARPGHAPGATAAQP--LGRSASRDNLAALAMPAAGVAILTAPLL
Mb2967|M.bovis_AF2122/97 AATMLAARLGSDAGHSAAP-------TYRDSLPAFALPGACVAIFTGPLL
Rv2942|M.tuberculosis_H37Rv AATMLAARLGSDAGHSAAP-------TYRDSLPAFALPGACVAIFTGPLL
MLBr_00137|M.leprae_Br4923 ASTLLASR--SYTGDSAAP-------TCRAHLPALALLGACVALLTGTLL
:: . .. . :: *
MSMEG_0382|M.smegmatis_MC2_155 FTRLPYFHTMGVPCAIGMLAAVAVAVTLVPAGVALAGRIGWLEP--KRKM
TH_3056|M.thermoresistible__bu FTRLPHFQPLGIPGAVGLLVAVAVALTLVPATIALGSRFGLFEP--KRRV
Mflv_2705|M.gilvum_PYR-GCK FTRMPYFQSMGIPCAVGIAAGVAVALTLGPAIVTVGSRFNLLEP--KRAM
Mvan_3833|M.vanbaalenii_PYR-1 FARMPYFQSMGVPCAVGILAGVAVALTLGPAIVTVGSRFGLLEP--KRAM
MAB_1520c|M.abscessus_ATCC_199 FAQVGMLRSAGLPCAIGILTGMVASLTLLPALIGLAGRRGLAQPRPLRGQ
MAV_5284|M.avium_104 FAHVGSFRSAGLPCAIGILATMVAALTLTPALMSLAVRRRYLEPRPSR--
MUL_2007|M.ulcerans_Agy99 LARTPALHGVGV-AALGVVVALAASLTLLPALIGLTGPSRLSSS------
MMAR_1764|M.marinum_M LARTPALHGVGV-AALGVVVALAASLTLLPALIGLTGPSRLSSS------
Mb2967|M.bovis_AF2122/97 LARTPALHGVGT-AGLGVFVALAASLTVLPALIALAGASRQLPA------
Rv2942|M.tuberculosis_H37Rv LARTPALHGVGT-AGLGVFVALAASLTVLPALIALAGASRQLPA------
MLBr_00137|M.leprae_Br4923 LARTPALHSVGT-VALGVVVALAASLTLLPTLIKLAGPSGQISP------
::: :: * .:*: . :..::*: *: : : .
MSMEG_0382|M.smegmatis_MC2_155 RVRRWRGIGTAIVRWPAPILVASLAVALVGLLALPGYETSYNDRDYIPAD
TH_3056|M.thermoresistible__bu MTHRWRRIGTAVVRWPVPILTAAVALSLVGLLTLPGYNPSYSDQEFIPDD
Mflv_2705|M.gilvum_PYR-GCK RIRAWRRIGTMVVRWPGPILVASLALALVGLAALPGYQTSYDDTRYVPES
Mvan_3833|M.vanbaalenii_PYR-1 RIRAWRRVGATVVRWPGPILVASLALALIGLAALPGYKTSYDDTRYIPES
MAB_1520c|M.abscessus_ATCC_199 PGRRWRRVGAMVSRWPGPVLAGSLLVLVVCALPVAGLRLGFDELAAQPLS
MAV_5284|M.avium_104 TARRWRRVGTTVARWPGPILVAALGLTLLVALPLAGMRIGFNEPAATPSS
MUL_2007|M.ulcerans_Agy99 RPVGARRTLPVSLPR---TAVVAALVLAVCAVPVIGMQWGIGDGPVNPAA
MMAR_1764|M.marinum_M RPVGARRTLPVSIPR---TAVVAALVLAVCAVPVIGMQWGIGDGPVNPAA
Mb2967|M.bovis_AF2122/97 PTTGAGWTGRLSLPVSSASALGTAAVLAICMLPIIGMRWGVAEN---PTR
Rv2942|M.tuberculosis_H37Rv PTTGAGWTGRLSLPVSSASALGTAAVLAICMLPIIGMRWGVAEN---PTR
MLBr_00137|M.leprae_Br4923 QVNGNTWTRRLLVPNFSSPARLTAVVLATCALPVIGMRLGLAED---HTA
: : .: * . . :
MSMEG_0382|M.smegmatis_MC2_155 IPANAGFAAADRHFSQARMT-PDILMVESDHDMRNPTDFLVLNKIAKAIF
TH_3056|M.thermoresistible__bu IPASEGYKAAARHFPASAMSVPDVVLIEADRDMRNPADLLVLNKVAKKIF
Mflv_2705|M.gilvum_PYR-GCK IPANAGLQAATQHFTLSRMS-PEILIVEADRDLRNPADFLVLDRLAKRVF
Mvan_3833|M.vanbaalenii_PYR-1 IPANAGLQAATKYFSLSRMS-PEVLIVEADRDLRNSSDFLILDRLAKRVF
MAB_1520c|M.abscessus_ATCC_199 THANRGYQAMDRHFPPNRLL-PEIVSIESDHDLRTPAGVIAVERVTKGLM
MAV_5284|M.avium_104 TDSNRGYASAGRHFPENALL-PDVIAIRADHDLRNPAGLIAIERITRHIM
MUL_2007|M.ulcerans_Agy99 GGT-------KRALPWQPLP--DVVMLEAKHDLSDPAGLIAIDQVSHRLM
MMAR_1764|M.marinum_M GGT-------KRALPWQPLP--DVVMLEAKHDLSDPAGLIAIDQVSHRLM
Mb2967|M.bovis_AF2122/97 QGG-------AQVLPGNALP--DVVVIKSARDLRDPAALIAINQVSHRLV
Rv2942|M.tuberculosis_H37Rv QGG-------AQVLPGNALP--DVVVIKSARDLRDPAALIAINQVSHRLV
MLBr_00137|M.leprae_Br4923 QSG-------TQILPGNLLP--DILLIKSARDLRDPAALIAIDQVSHRLM
: :. : ::: :.: :*: .: .: :::::: :.
MSMEG_0382|M.smegmatis_MC2_155 KVRGVSRVQGITRPEGTPIERTSIPFLLSLQSAGQVQATNFQKQRIGDML
TH_3056|M.thermoresistible__bu EVPGVANVQSVTRPEGRQIEHTTIPFMLSMSQASQRLALPFQRARMDDML
Mflv_2705|M.gilvum_PYR-GCK AVEGVARVQAPSRPDGSPIAKTSIPFLISMQGVGQQQNMKLMQDRMDDMR
Mvan_3833|M.vanbaalenii_PYR-1 NVEGVARVQAPSRPDGAPIAHTSIPFLISMQGVGQQQNMKLMKDRIADMR
MAB_1520c|M.abscessus_ATCC_199 EIPGIRMVQSASRPAGTIPEQAALTEQAGIIADQLDDGTAQMSQRLGAVD
MAV_5284|M.avium_104 AVPGVRAVQSASRPDGKVPEQATLSYQAGVLGRQFGDTVDSLTQRLARVS
MUL_2007|M.ulcerans_Agy99 EIPGVRRVESAAWPAGVPWTDASLTAAAGKLSDELDRGAGSFMPQVRAIK
MMAR_1764|M.marinum_M EIPGVRRVESAAWPAGVPWTDASLTAAAGKLSDELDRGAGSFMPQVRAIK
Mb2967|M.bovis_AF2122/97 EVPGVRKVESAAWPAGVPWTDASLSSAAGRLADQLGQQAGSFVPAVTAIK
Rv2942|M.tuberculosis_H37Rv EVPGVRKVESAAWPAGVPWTDASLSSAAGRLADQLGQQAGSFVPAVTAIK
MLBr_00137|M.leprae_Br4923 EIPGVRKVESAAWPAGVPWNDASLSSAAGRLADQMSQQAGSFVPAVTAIK
: *: *:. : * * :::. . : :
MSMEG_0382|M.smegmatis_MC2_155 KQVDDMNMMIGVMKTTYGVLQELAATTHSLNGSTHELRDVARDLRGSIAI
TH_3056|M.thermoresistible__bu KQADELTETIALMRRMQSLMEKMVATTHSMVGTTHELLDTTRDLRDHIAD
Mflv_2705|M.gilvum_PYR-GCK TQADNLGKTLGTMRTMYGLMTRLSEVTTVMIDDFTEMQQTVHQIRDMVAN
Mvan_3833|M.vanbaalenii_PYR-1 VQADDIGETIATMKTMYGLMTKFSNITTVMIDDMTEMRDTVHQIRDMVAT
MAB_1520c|M.abscessus_ATCC_199 KLSATLSQFSGAIAQLQKGLAGGVNGLGELNGGIGDMHSGMKALQDNVSQ
MAV_5284|M.avium_104 ELDGALAQTQQAVDGLGNGLHGGSAGLADMSGAADDMRAGMDGLQRNVTT
MUL_2007|M.ulcerans_Agy99 TLGSIVDQMSGAVDELDRSVTAGLAGAAQIQQNVDLLISGTKNIKGVTVE
MMAR_1764|M.marinum_M TLGSIVDQMSGAVDELDRSVTAGLAGAAQIQQNVDLLISGTKNIKGVTVE
Mb2967|M.bovis_AF2122/97 SMKSIIEQMSGAVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTE
Rv2942|M.tuberculosis_H37Rv SMKSIIEQMSGAVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTE
MLBr_00137|M.leprae_Br4923 QMKTMIDQMSSTVDELESTVNVALAGAHQVQQYLNPVLSAARNIKSKTAE
: : : : ::
MSMEG_0382|M.smegmatis_MC2_155 FDDLLRPIRNYFYWEPHCYNIPICWSLRSIFDAMDGVDRLNDELQVLVDN
TH_3056|M.thermoresistible__bu FDDFFRPIRNYFHWEPHCYNIPICWSIRSIFDALDGINEMTEKMEELVED
Mflv_2705|M.gilvum_PYR-GCK FDDQFRPVRNYFYWEPHCYNIPLCWSFRSLFDSMDGISTMTESFDKALVN
Mvan_3833|M.vanbaalenii_PYR-1 FDDQFRPIRNYFYWEPHCYNIPLCWSFRSLFDSMDGISVMTDTFDKAVAN
MAB_1520c|M.abscessus_ATCC_199 VSGYMEPLRNFTNGNPNCANDGICSLVLKAVEPMDSVVAATASLTASTTK
MAV_5284|M.avium_104 VSGYLDPLRDLVGRTPDCAANPICSMVDRVLAPVDSLVQTSAQLGSGAAK
MUL_2007|M.ulcerans_Agy99 LSGYLDPVRGWMGDVPNCPGDMLCVAAGKVIDPVDRVVDDVKLLTDGADR
MMAR_1764|M.marinum_M LSGYLDPVRGWMGDVPNCPGDMLCVAAGKVIDPVDRVVDDVKLLTDGADR
Mb2967|M.bovis_AF2122/97 LSEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADR
Rv2942|M.tuberculosis_H37Rv LSEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADR
MLBr_00137|M.leprae_Br4923 FSGYLDTVRGWVVSVTNCPNDVLCSAMRKVIEPYDKVAASMDQLSNGVDR
.. : .:: ..* :* . . * : :
MSMEG_0382|M.smegmatis_MC2_155 MDRLDALVPELVAQFPEYIASMETFRELTLTSYSTFSGLLQQMDEQTEDV
TH_3056|M.thermoresistible__bu MDRLDALMPQMLVQFPQMIETMESSRTMILTMHATMSGIFDQMESSSENA
Mflv_2705|M.gilvum_PYR-GCK METMRSLLPQMLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTQDS
Mvan_3833|M.vanbaalenii_PYR-1 MDEMKALLPQMLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTRDS
MAB_1520c|M.abscessus_ATCC_199 FGAGAQGMQKSFSGAVDSVKNMRATVAQLGAITDQLTHAVGETRTMFSGL
MAV_5284|M.avium_104 LTTGSNTAATAMAGLPQNVDAMKSALVQARSATRDLLGLSDTLGPQMRQL
MUL_2007|M.ulcerans_Agy99 IAAVSRKTVGAFSSAPHVVAQMRSALAQLQSFVPNLETTIENTLPQLVQV
MMAR_1764|M.marinum_M IAAVSRKTVGAFSSAPQVVAQMRSALAQLQSFVPNLETTIENTLPQLVQV
Mb2967|M.bovis_AF2122/97 ISAISTQTMSALSSAPRMVAQMRSALAQVRSFVPKLETTIQDAMPQIAQA
Rv2942|M.tuberculosis_H37Rv ISAISTQTMSALSSAPRMVAQMRSALAQVRSFVPKLETTIQDAMPQIAQA
MLBr_00137|M.leprae_Br4923 ISAISDQTISSFNEAPHMVAQMRSALKQARSFIPRLESTIQELMPQIAQA
: . : *.: : :
MSMEG_0382|M.smegmatis_MC2_155 TAMGQAFDAAKNDDT---FFLPPEVFDNPDFKRAMTSFLSPDGKAARFII
TH_3056|M.thermoresistible__bu TAMGKAFDASHNDDS---FYLPPEALENKDFQRVMEIFLSPDGKAARMLV
Mflv_2705|M.gilvum_PYR-GCK TEMGKAFDEAKNDDS---FYLPPEVFENEDFKRAMESFFSPDGKTVRMLV
Mvan_3833|M.vanbaalenii_PYR-1 TEMGKAFDAAKNDDS---FYLPPEVFENEDFKRAMESFFSPDGKTVRMLI
MAB_1520c|M.abscessus_ATCC_199 TEYLRAMREDFRSSGEGGYYLPQRAWQDPRFQRAAGLYFGPDGHSTRMLV
MAV_5284|M.avium_104 TDYLNEISTQFQGSAAADFYLPQRALTDPRYTAVLNHLISQTGRAAYLLV
MUL_2007|M.ulcerans_Agy99 SAFLKNLRLDFANTGQGDFYLSGKALADPSYQQVRQSMFSADGTATRLLV
MMAR_1764|M.marinum_M SAFLKNLRLDFANTGQGGFYLSGKALADPSYQQVRQSMFSADGTATRLLV
Mb2967|M.bovis_AF2122/97 SAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFSSDGTATRLFL
Rv2942|M.tuberculosis_H37Rv SAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFSSDGTATRLFL
MLBr_00137|M.leprae_Br4923 SAMLKNLSRDFADTGEGGFHLPMKELMSSSYQHVRESMFSSDGTATRLVV
: . : . :.*. . . : . :. * :. :.:
MSMEG_0382|M.smegmatis_MC2_155 SHNGDPATPEGISRVDQMQTAAVEALKGTPLTDAQVYLAGTAPTAKDWKD
TH_3056|M.thermoresistible__bu TQRGDPATPEGMALVEPIYIAAEEALKGTPLESSRIYLAGSAAGVKDLVE
Mflv_2705|M.gilvum_PYR-GCK SHRGDPTTPEALARVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSD
Mvan_3833|M.vanbaalenii_PYR-1 AHRGNPTTDEALQRVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSD
MAB_1520c|M.abscessus_ATCC_199 FGDGKVFGADGAHRSPQIMLAVSEATKEGTLAGSSVNLTGFGTGTAELRG
MAV_5284|M.avium_104 YGDGAEWGADSAERAEQVRAAIKEATKEGTLTPVEVDLAGVGPVTADLQR
MUL_2007|M.ulcerans_Agy99 FSEGN-PGLDASARAQQLEAAAGKAMKYGSLEDAEITVNGAAQVATDVRG
MMAR_1764|M.marinum_M FSEGN-PGLDASARAQQLEAAAGKAMKYGSLEDAEITVNGAAQVATDVRG
Mb2967|M.bovis_AF2122/97 YSDGQ-LDLAAAARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRD
Rv2942|M.tuberculosis_H37Rv YSDGQ-LDLAAAARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRD
MLBr_00137|M.leprae_Br4923 YTNEHNPGLDTAARAQQLEIAAGKAMKYGSLVDSRITLGGAAQVAVAARA
: * :* * .* : : * .
MSMEG_0382|M.smegmatis_MC2_155 GSTYDLLIAGIAAMCLIFIIMLIVTRSFIAALVIVGTVVLSLGASFGLSV
TH_3056|M.thermoresistible__bu GAKYDLMIAAISAVCLIFMIMVFMTRSVIAALVIVGTVVLSLGASFGMSV
Mflv_2705|M.gilvum_PYR-GCK GSRYDMMIAILSALCLVLVIMLVLTRSLVAAVVIVGTVALSLGASFGVSV
Mvan_3833|M.vanbaalenii_PYR-1 GSRYDLLIAVISALCLVLMIMLVLTRSLVAALVIVGTVTLSLGASFGISI
MAB_1520c|M.abscessus_ATCC_199 YVSEDFLLLAAVALALVFLIVLVMLRSPVAAAVVIGTVIISYASALGVTT
MAV_5284|M.avium_104 FVADDTRLLVGAALVLIFLIVTAMLRSPVAGLVVVGTVVTSYASAIGASV
MUL_2007|M.ulcerans_Agy99 SLTHDAVLLAAMMLAAVVLVS--MWRGALTAVVMAVGLLAAYLAALGIST
MMAR_1764|M.marinum_M SLTHDAVLLAAMMLAAVVLVS--MWRGALTAVVMAVGLLAAYLAALGIST
Mb2967|M.bovis_AF2122/97 ALIHDAVLLAVILLTVVALAS--MWRGAVHGAAVGVGVLASYLAALGVSI
Rv2942|M.tuberculosis_H37Rv ALIHDAVLLAVILLTVVALAS--MWRGAVHGAAVGVGVLASYLAALGVSI
MLBr_00137|M.leprae_Br4923 ALTHDAVLLAGMLFAVVALAS--MWVSAGSGVAVGLGVLAAYLGGLGISV
* : . : : : . . .: : : ..:* :
MSMEG_0382|M.smegmatis_MC2_155 LLWQYILGIHLHWMVLAMSVIILLAVGSDYNLLLVSRIKEEVG----AGI
TH_3056|M.thermoresistible__bu LLWQHLLGIQLHWVVLAMSVIVLLAVGSDYNLMLVSRMKEEIG----AGL
Mflv_2705|M.gilvum_PYR-GCK LIWQHLLGVELHWMVLVMSIIALIAVGSDYNLLLVSRFKEEIG----AGI
Mvan_3833|M.vanbaalenii_PYR-1 LIWQHIVGIELHWMVLALSIIALIAVGSDYNLLLVSRFKEEIP----AGI
MAB_1520c|M.abscessus_ATCC_199 LIWQDLLGRDLHWAVPSIALIALVAVGADYNLLLTMRMREEVFLH-GAGL
MAV_5284|M.avium_104 LIWQHLLHQELHWAVAPIAFIALIAVGADYNLLLALRIKQEA----AAGL
MUL_2007|M.ulcerans_Agy99 ALWQYLAGREIPAAVPLVSFAILAACGLPYLLD-RTATPISTEAPITSDA
MMAR_1764|M.marinum_M ALWQYLAGREIPAAVPLVSFAILAACGLPYLLD-RTATPISTEAPITSDA
Mb2967|M.bovis_AF2122/97 ALWQHLLDRELNALVPLVSFAVLASCGVPYLVAGIKAGRIADEA---TGA
Rv2942|M.tuberculosis_H37Rv ALWQHLLDRELNALVPLVSFAVLASCGVPYLVAGIKAGRIADEA---TGA
MLBr_00137|M.leprae_Br4923 ALWQHILGHELQASVPLVSFAILAPCGVLYLVTSLEAARVSAEA---KTA
:** : .: * ::. * . * * :
MSMEG_0382|M.smegmatis_MC2_155 NTGIVRAMGGTGKVVTSAGLVFAGTMAAMVVSDLRIIGQIGTTIGLGLLF
TH_3056|M.thermoresistible__bu NTGIIRAMGGTGRVVTMAGLVFAATMASMIVSDLLMIGQVGTTIALGLLF
Mflv_2705|M.gilvum_PYR-GCK KTGIIRAIGGTGSVVSVAGVVFALTMASMVVSDLKVIAQVGTTIGLGLLF
Mvan_3833|M.vanbaalenii_PYR-1 KTGIIRAIGGTGSVVTVAGVVFALTMASMVVSDLRVMAQVGTTIGLGLLF
MAB_1520c|M.abscessus_ATCC_199 RTGMIRTFGGTGGVVTTAGIVFGITMFAMLSSDVLSIEQTGTTIGVGLMI
MAV_5284|M.avium_104 RTGIIRAFGGTGGVVTVAGIIFGLTMLALLTSSVLSIAQIGTTIAVGLLL
MUL_2007|M.ulcerans_Agy99 QPADTAALRNAGAPLAALTAVFGLGLVLVSAGSLGALSQIGTVVLFGVAA
MMAR_1764|M.marinum_M QPADTAALRNAGAPLAALTAVFGLGLVLVSAGSLGALSQIGTVVLFGVAA
Mb2967|M.bovis_AF2122/97 RSKGAVSGRGAVAPLAALGGVFGAGLVLVSGGSFSVLSQIGTVVVLGLGV
Rv2942|M.tuberculosis_H37Rv RSKGAVSGRGAVAPLAALGGVFGAGLVLVSGGSFSVLSQIGTVVVLGLGV
MLBr_00137|M.leprae_Br4923 AT---VSVRRAVVPLTVLGAIFGAGLVVAEA-SFSALSQVGTVLVIALGA
. : : :: :*. : .. : * **.: ..:
MSMEG_0382|M.smegmatis_MC2_155 DTMIVRSFMTPSIAALLGRWFWWPQKVRPRPASALLEPYGPRPLVRALLE
TH_3056|M.thermoresistible__bu DTMVVRAFMTPSVAAILGRWFWWPQRVRTRPASAMLRPVGPRPLVRSLLL
Mflv_2705|M.gilvum_PYR-GCK DTFIVRAFMMPSIATLLGRWFWWPLVVRSR-------PLRPRPQQQALGV
Mvan_3833|M.vanbaalenii_PYR-1 DTFIVRAFMMPAIATLLGRWFWWPLVVRSR-------PLRLPPRT-----
MAB_1520c|M.abscessus_ATCC_199 DTLIVRTFVVPAIAGALGKWFWWSPVPLLRGLLFRWSKARSPRTAGVLSY
MAV_5284|M.avium_104 DTLVVRAFIVPSIVALLGRWFWW-PSPLPRRGVARVVKTVEPQPVSVATA
MUL_2007|M.ulcerans_Agy99 LTVLARVCIP-AAMQDRADRTTVATEPVAQPD------------------
MMAR_1764|M.marinum_M LTVLARVCIP-AAIQDRADRTTVATEPVAQPD------------------
Mb2967|M.bovis_AF2122/97 LITVQRAWLP-----------TTPGRR-----------------------
Rv2942|M.tuberculosis_H37Rv LITVQRAWLP-----------TTPGRR-----------------------
MLBr_00137|M.leprae_Br4923 LTKVEQVLISYHAEAAMPAWSKLPSRLSGGPN------------------
: : :
MSMEG_0382|M.smegmatis_MC2_155 GPSGAASPGGPGGRLSDDDTPTGPMRTR
TH_3056|M.thermoresistible__bu RD--------------------------
Mflv_2705|M.gilvum_PYR-GCK GGQQG-----------------------
Mvan_3833|M.vanbaalenii_PYR-1 ----------------------------
MAB_1520c|M.abscessus_ATCC_199 LLTRPSRLERTGA---------------
MAV_5284|M.avium_104 V---------------------------
MUL_2007|M.ulcerans_Agy99 ----------------------------
MMAR_1764|M.marinum_M ----------------------------
Mb2967|M.bovis_AF2122/97 ----------------------------
Rv2942|M.tuberculosis_H37Rv ----------------------------
MLBr_00137|M.leprae_Br4923 ----------------------------