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M. smegmatis MC2 155 MSMEG_2206 (fabG)

annotation: 3-ketoacyl-(acyl-carrier-protein) reductase
coordinates: 2286455 - 2287189
length: 244

LLTGQTAVVTGGAQGLGLAIAKRFISEGARVVLGDLNSEATEAAVEELGGSEVAAAVRCDVTSSADVDAL
VQAAVERFGGLDIMVNNAGITRDATLRKMTEEQFDQVIAVHLKGTWNGTKAAAAIMRENKRGAIVNMSSI
SGKVGLIGQTNYSAAKAGIVGMTKAAAKELAYLGVRVNAIQPGLIRSAMTEAMPQRIWDEKLAEIPMGRA
GEPDEVAKVALFLASDLSSYMTGTVLEVTGGRHV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2206fabG-100% (244)3-ketoacyl-(acyl-carrier-protein) reductase
M. smegmatis MC2 155MSMEG_4859-1e-4542.13% (254) oxidoreductase, short chain dehydrogenase/reductase family
M. smegmatis MC2 155MSMEG_3150fabG1e-4340.51% (237) 3-oxoacyl-(acyl-carrier-protein) reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1385fabG1e-11381.97% (244) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_4369fabG1e-11886.48% (244) 3-ketoacyl-(acyl-carrier-protein) reductase
M. tuberculosis H37RvRv1350fabG1e-11381.97% (244) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_01807fabG17e-4136.29% (237) 3-oxoacyl-
M. abscessus ATCC 19977MAB_2723c-2e-4438.82% (237) 3-oxoacyl-
M. marinum MMMAR_4033fabG1e-11584.02% (244) 3-oxoacyl-
M. avium 104MAV_1572-1e-11783.61% (244) short chain dehydrogenase
M. thermoresistible (build 8)TH_3693-1e-11584.43% (244) PUTATIVE short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_3898fabG1e-11384.81% (237) 3-ketoacyl-(acyl-carrier-protein) reductase
M. vanbaalenii PYR-1Mvan_1975fabG1e-11785.66% (244) 3-ketoacyl-(acyl-carrier-protein) reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4369|M.gilvum_PYR-GCK          ----------------MSLLTG--QTAVITGGAQGLGFAIAQRFVDEGAR
Mvan_1975|M.vanbaalenii_PYR-1       ----------MRMGEQVSLLTG--QTAVITGGAQGLGFAIAQRFVEEGAR
TH_3693|M.thermoresistible__bu      ----------------VSLLAG--QTAVVTGGARGLGYAIAERFIAEGAR
MSMEG_2206|M.smegmatis_MC2_155      ------------------MLTG--QTAVVTGGAQGLGLAIAKRFISEGAR
MMAR_4033|M.marinum_M               --------------MSVSLLNG--QIAVVTGGAQGLGLAIAERFVSEGAR
MUL_3898|M.ulcerans_Agy99           --------------MCGAHRDRGYVYPVVTGGAQGLGLAIAERFVSEGAR
MAV_1572|M.avium_104                ----------------MSLLSG--QTAVITGGAQGLGFAIAERFVAEGAR
Mb1385|M.bovis_AF2122/97            ---------------MASLLNA--RTAVITGGAQGLGLAIGQRFVAEGAR
Rv1350|M.tuberculosis_H37Rv         ---------------MASLLNA--RTAVITGGAQGLGLAIGQRFVAEGAR
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSR---SILVTGGNRGIGLAVARRLVADGHR
MAB_2723c|M.abscessus_ATCC_199      MTNA-------------EFVPR---SVLVTGGNRGIGLAVAQRLAADGHK
                                                               ::*** :*:* *:..*:  :* :

Mflv_4369|M.gilvum_PYR-GCK          VVLGDVNLEATQEAAEKLGGADVAHAVRCDVTSSAEVDALVAAAVDTFGA
Mvan_1975|M.vanbaalenii_PYR-1       VVLGDVNLDATVAAAEKLGGEDVARAVRCDVTDSAEVDALIAAAVDGFGS
TH_3693|M.thermoresistible__bu      VVIGDIDESATRAAADSLGGADVAVGMRCDVTRSDEVEALVGAAVKRFGS
MSMEG_2206|M.smegmatis_MC2_155      VVLGDLNSEATEAAVEELGGSEVAAAVRCDVTSSADVDALVQAAVERFGG
MMAR_4033|M.marinum_M               VVLGDVNLEATEAAAKQLGGGEVAVAVRCDVTKADEVETLLQTALERFGG
MUL_3898|M.ulcerans_Agy99           VVLGDVNLEATEAAAKQLGGGEVAVAVRCDVTKADEVETLLQAALERFGG
MAV_1572|M.avium_104                VVLGDVNLEATQTAAKQLGGDQVALAVRCDVTKSSEVETLIQTAVERFGG
Mb1385|M.bovis_AF2122/97            VVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGG
Rv1350|M.tuberculosis_H37Rv         VVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGG
MLBr_01807|M.leprae_Br4923          VAVTHR---ASVVPDWFFG-------VECDVTDNDAIGAAFKAVEEHQGP
MAB_2723c|M.abscessus_ATCC_199      VAVTHR---GSGAPEGLLG-------VQCDITDNDQIDAAFKEVEEKQGP
                                    *.: .    .:  .   :*       :.**:*    :   .  . .  * 

Mflv_4369|M.gilvum_PYR-GCK          LDIMVNNAGITRDATMRKMTEDDFDKVIAVHLKGTWNGLRAAAAIMRENK
Mvan_1975|M.vanbaalenii_PYR-1       LDIMVNNAGITRDATMRKMTEEQFDQVIAVHLKGTWNGLRAAAAVMREQK
TH_3693|M.thermoresistible__bu      LDVMVNNAGITRDATMRKMTEQQFDEVIAVHLKGTWNGLRAAAAIMREQK
MSMEG_2206|M.smegmatis_MC2_155      LDIMVNNAGITRDATLRKMTEEQFDQVIAVHLKGTWNGTKAAAAIMRENK
MMAR_4033|M.marinum_M               LDIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENK
MUL_3898|M.ulcerans_Agy99           LDIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENK
MAV_1572|M.avium_104                LDIMVNNAGITRDATMRKMTEEQFDQVIAVHLKGTWNGTRLAAAIMRENK
Mb1385|M.bovis_AF2122/97            LDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERK
Rv1350|M.tuberculosis_H37Rv         LDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERK
MLBr_01807|M.leprae_Br4923          VEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
MAB_2723c|M.abscessus_ATCC_199      VEVLVANAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKR
                                    ::::* ***** *  :  *:*::* :** .:* *.:.  : *:  * :.:

Mflv_4369|M.gilvum_PYR-GCK          RGVIVNMSSISGKVGMIGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAI
Mvan_1975|M.vanbaalenii_PYR-1       RGAIVNMSSISGKVGMVGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAI
TH_3693|M.thermoresistible__bu      RGAIVNMSSISGKVGMVGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAI
MSMEG_2206|M.smegmatis_MC2_155      RGAIVNMSSISGKVGLIGQTNYSAAKAGIVGMTKAAAKELAYLGVRVNAI
MMAR_4033|M.marinum_M               RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHVGVRVNAI
MUL_3898|M.ulcerans_Agy99           RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHVGVRVNAI
MAV_1572|M.avium_104                RGAIINMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAYLGVRVNAI
Mb1385|M.bovis_AF2122/97            RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAI
Rv1350|M.tuberculosis_H37Rv         RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAI
MLBr_01807|M.leprae_Br4923          FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
MAB_2723c|M.abscessus_ATCC_199      FGRLIFMGSVAGQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVV
                                     *  : *.*: *  *: **:**:*:*:*::**::: ::**.  .: .*.:

Mflv_4369|M.gilvum_PYR-GCK          QPGLIRSAMTEAMPQRIWDSKVAEVPLGRAGEPDEVAKVALFLASDLSSY
Mvan_1975|M.vanbaalenii_PYR-1       QPGLIRSAMTEAMPQRIWDSKVAEVPMGRAGEPEEVANVALFLASDLSSY
TH_3693|M.thermoresistible__bu      QPGLIRSAMTEAMPQRIWDEKLAEIPMGRAGEPEEVAKVALFLASDLSSY
MSMEG_2206|M.smegmatis_MC2_155      QPGLIRSAMTEAMPQRIWDEKLAEIPMGRAGEPDEVAKVALFLASDLSSY
MMAR_4033|M.marinum_M               APGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVALFLACDLSSY
MUL_3898|M.ulcerans_Agy99           APGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVALFLACDLSSY
MAV_1572|M.avium_104                APGLIRSAMTEAMPQRIWDSKVAEVPMGRAGEPSEVASVALFLASDMSSY
Mb1385|M.bovis_AF2122/97            APGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSSY
Rv1350|M.tuberculosis_H37Rv         APGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSSY
MLBr_01807|M.leprae_Br4923          APGFIDTEMTRAMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGY
MAB_2723c|M.abscessus_ATCC_199      APGFIDTDMTRELGEKHVETALTAIPMGRIGEPSEVAGVVSWLASPDAAY
                                     **:* : **. : .:  :  :  :*:** *  .*:* .. :**.  :.*

Mflv_4369|M.gilvum_PYR-GCK          MTGTVLEVTGGRHL--
Mvan_1975|M.vanbaalenii_PYR-1       MTGTVLEVTGGRHL--
TH_3693|M.thermoresistible__bu      MTGTVLEVTGGRHL--
MSMEG_2206|M.smegmatis_MC2_155      MTGTVLEVTGGRHV--
MMAR_4033|M.marinum_M               MTGTVLDVTGGRFI--
MUL_3898|M.ulcerans_Agy99           MTGTVLDVTGGRFI--
MAV_1572|M.avium_104                MTGTVMEITGGRHL--
Mb1385|M.bovis_AF2122/97            MTGTVLDVTGGRFI--
Rv1350|M.tuberculosis_H37Rv         MTGTVLDVTGGRFI--
MLBr_01807|M.leprae_Br4923          ISGAVIPVDGGLGMGH
MAB_2723c|M.abscessus_ATCC_199      VSGAVIPVDGGLGMGH
                                    ::*:*: : **  :