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M. vanbaalenii PYR-1 Mvan_3999 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 4274939 - 4275709
length: 256

TYPDLADKAVIVTGAAAGIGLAIAERLAAERCRVVCADIDGAAADAAAAAIGNGAVGYAVDVSDEPQVVG
MVEACVAAFGGVDKLVANAGVVHFAPLTETTVDDFDRIIGINLRGAWLCTKHAAPRMAERGGGAIVNMSS
LGGLVAAAGTAAYGMSKAGIIHLSRITAAEMRSANIRSNALLPAFVDTPMQQTAMTMFDEALGDGGAATM
IGRLQGRMAGPAEMAGVVAFLLSDAASMVNGTAQLADGGTLAALW*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_3999--100% (256)short-chain dehydrogenase/reductase SDR
M. vanbaalenii PYR-1Mvan_4237-8e-3736.40% (261) short-chain dehydrogenase/reductase SDR
M. vanbaalenii PYR-1Mvan_1975fabG3e-3635.22% (247) 3-ketoacyl-(acyl-carrier-protein) reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1976-1e-10876.17% (256) short-chain type dehydrogenase/reductase
M. gilvum PYR-GCKMflv_4369fabG3e-3635.22% (247) 3-ketoacyl-(acyl-carrier-protein) reductase
M. tuberculosis H37RvRv1941-1e-10876.17% (256) short-chain type dehydrogenase/reductase
M. leprae Br4923MLBr_01807fabG11e-2831.17% (247) 3-oxoacyl-
M. abscessus ATCC 19977MAB_4680c-4e-3738.71% (248) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_2869-1e-11378.74% (254) short-chain type dehydrogenase/reductase
M. avium 104MAV_5088fabG5e-4241.53% (248) 3-ketoacyl-(acyl-carrier-protein) reductase
M. smegmatis MC2 155MSMEG_3607-2e-3939.60% (250) short chain dehydrogenase
M. thermoresistible (build 8)TH_3954-4e-3940.82% (245) PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase
M. ulcerans Agy99MUL_2885-1e-11177.95% (254) short-chain type dehydrogenase/reductase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2869|M.marinum_M               MRYP-------------DLAGKATIVTGAGAGIGLAIAERLAAEGAAVLC
MUL_2885|M.ulcerans_Agy99           MRYP-------------DLAGKATIVTGAGAGIGLAIAERLAAEGAAVLC
Mvan_3999|M.vanbaalenii_PYR-1       MTYP-------------DLADKAVIVTGAAAGIGLAIAERLAAERCRVVC
Mb1976|M.bovis_AF2122/97            MNHP-------------DLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Rv1941|M.tuberculosis_H37Rv         MNHP-------------DLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
MSMEG_3607|M.smegmatis_MC2_155      MTQAQELSVDF----DFRLDGKVALVTGAASGIGAAIASAYATKGARIAA
MAV_5088|M.avium_104                MAES-------------LLLGKVAVVTGAGQGIGREIARALHRHGARVVL
TH_3954|M.thermoresistible__bu      MPSA-------------LLAEKVAVVTGAGRGIGREIARVLHAHGAEVVL
Mflv_4369|M.gilvum_PYR-GCK          --MS-------------LLTGQTAVITGGAQGLGFAIAQRFVDEGARVVL
MAB_4680c|M.abscessus_ATCC_199      MNGNS-----------ALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                      :  :  ::**.  *:*  .:     .   :  

MMAR_2869|M.marinum_M               ADIDGASAEQAAAKIG---SGAVGYQVDVSAEEQVAGMVEACVTSFGGLD
MUL_2885|M.ulcerans_Agy99           ADIDGASAEQAAAKIG---SGAVGYQVDVSAEEQVAGMVEACVTSFGGLD
Mvan_3999|M.vanbaalenii_PYR-1       ADIDGAAADAAAAAIG---NGAVGYAVDVSDEPQVVGMVEACVAAFGGVD
Mb1976|M.bovis_AF2122/97            ADIDGDAADAAATKIG---CGAAACRVDVSDEQQIIAMVDACVAAFGGVD
Rv1941|M.tuberculosis_H37Rv         ADIDGDAADAAATKIG---CGAAACRVDVSDEQQIIAMVDACVAAFGGVD
MSMEG_3607|M.smegmatis_MC2_155      VDLNAEGAEALAAQLGGDRGAHRGFACDVADAASVQAAADAVAAEFGRID
MAV_5088|M.avium_104                ADLDGSAARSAAAQIDDSGANCTGLACDVTSEEQVGALVAGTVREHGGLD
TH_3954|M.thermoresistible__bu      ADLDADAAAQAAAEVDG-----TGVGCDVTAEDQMKRLVADTVAKHGRLD
Mflv_4369|M.gilvum_PYR-GCK          GDVNLEATQEAAEKLGG-ADVAHAVRCDVTSSAEVDALVAAAVDTFGALD
MAB_4680c|M.abscessus_ATCC_199      ADVLDGDGRQLAAELG---DAARFTHLDVTDAEQWRELIDTTLAGFGTIT
MLBr_01807|M.leprae_Br4923          THRASVVP-----------DWFFGVECDVTDNDAIGAAFKAVEEHQGPVE
                                     .                         **:                * : 

MMAR_2869|M.marinum_M               KLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGG
MUL_2885|M.ulcerans_Agy99           KLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGG
Mvan_3999|M.vanbaalenii_PYR-1       KLVANAGVVHFAPLTETTVDDFDRIIGINLRGAWLCTKHAAPRMAERGGG
Mb1976|M.bovis_AF2122/97            KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG
Rv1941|M.tuberculosis_H37Rv         KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG
MSMEG_3607|M.smegmatis_MC2_155      ILVNSAGVARLAPAEELSLQDWDSTLAINLSGTFLMCQAVGKRMLEAGGG
MAV_5088|M.avium_104                VFVNNAGITRDASLKRMTVADFDAVIAVHLRGTWLGVREAAAVMRERKTG
TH_3954|M.thermoresistible__bu      LFVNNAGITRDASLKRMTVADFDAVVTVHLRGTWLGVREATAVMREQKSG
Mflv_4369|M.gilvum_PYR-GCK          IMVNNAGITRDATMRKMTEDDFDKVIAVHLKGTWNGLRAAAAIMRENKRG
MAB_4680c|M.abscessus_ATCC_199      GLVNNAGISSAAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHGCG
MLBr_01807|M.leprae_Br4923          VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG
                                     :* .**:         .  .:   : ::* *.:   : .   *     *

MMAR_2869|M.marinum_M               AIVNMSSLAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLP
MUL_2885|M.ulcerans_Agy99           AIVNMSSLAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLP
Mvan_3999|M.vanbaalenii_PYR-1       AIVNMSSLGGLVAAAGTAAYGMSKAGIIHLSRITAAEMRSANIRSNALLP
Mb1976|M.bovis_AF2122/97            AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP
Rv1941|M.tuberculosis_H37Rv         AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP
MSMEG_3607|M.smegmatis_MC2_155      AIVNMASQAATVALDQHVAYCASKFGVVGVSKVLAAEWGGRGVRVNTISP
MAV_5088|M.avium_104                SIVNMSSLSGKAGNPGQTNYSAAKAGIVGLTKAAAKELAHHNVRVNAIQP
TH_3954|M.thermoresistible__bu      SIVNISSLSGKSGNPGQTNYSAAKAGIIGLTKAAAKEVAHHNVRVNAIQP
Mflv_4369|M.gilvum_PYR-GCK          VIVNMSSISGKVGMIGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAIQP
MAB_4680c|M.abscessus_ATCC_199      SIVNISSAAGLVGLALTSGYGASKWGVRGLSKVAAIELGRERIRVNSVHP
MLBr_01807|M.leprae_Br4923          RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAP
                                      : :.*  .  .      *  :* *:  :::  : *     :  * : *

MMAR_2869|M.marinum_M               AFVDTPMQQSAMAMFDEALGTGGANTMIARLQGRMARPEEMASIVAFLLS
MUL_2885|M.ulcerans_Agy99           AFVDTPMQQSAMAMFDEVLGTGGANTMIARLQGRMARPEEMARIVAFLLP
Mvan_3999|M.vanbaalenii_PYR-1       AFVDTPMQQTAMTMFDEALGDGGAATMIGRLQGRMAGPAEMAGVVAFLLS
Mb1976|M.bovis_AF2122/97            AFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEMAGIVVFLLS
Rv1941|M.tuberculosis_H37Rv         AFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEMAGIVVFLLS
MSMEG_3607|M.smegmatis_MC2_155      TVVLTELGHKA---WDGPRGD-ALKKLIP--TGRFAYPDEIAAAAVFLAS
MAV_5088|M.avium_104                GLIRTPMTAAMP-------PDVFAEREAAVPMKRAGEPEEVAGAVVFLAS
TH_3954|M.thermoresistible__bu      GLIRTPMTETMP-------AEVFAEREAAVPMKRAGEPAEVAGAVVFLGS
Mflv_4369|M.gilvum_PYR-GCK          GLIRSAMTEAMP-------QRIWDSKVAEVPLGRAGEPDEVAKVALFLAS
MAB_4680c|M.abscessus_ATCC_199      GVIYTPMTAKEG-------FREGEGNMPIAAMGRVGNADEVAGAVAYLLS
MLBr_01807|M.leprae_Br4923          GFIDTEMTRAMD-------SKYQEAALQAIPLGRIGAVEEIAGAVSFLAS
                                     .: : :                          * .   *:*  . :* .

MMAR_2869|M.marinum_M               DDSSMITGTTQIADGGTIAALW-------
MUL_2885|M.ulcerans_Agy99           DDSSMITGTTQIADGGTIAALW-------
Mvan_3999|M.vanbaalenii_PYR-1       DAASMVNGTAQLADGGTLAALW-------
Mb1976|M.bovis_AF2122/97            DDASMITGTTQIADGGTIAALW-------
Rv1941|M.tuberculosis_H37Rv         DDASMITGTTQIADGGTIAALW-------
MSMEG_3607|M.smegmatis_MC2_155      DAAAMINGADLVIDGGYTIK---------
MAV_5088|M.avium_104                ELSSYITGTVLGVGGGRYM----------
TH_3954|M.thermoresistible__bu      DLSSYITGSVIEVGGGRYM----------
Mflv_4369|M.gilvum_PYR-GCK          DLSSYMTGTVLEVTGGRHL----------
MAB_4680c|M.abscessus_ATCC_199      DAASYVTGAELAVDGGWTAGPTLTTITGQ
MLBr_01807|M.leprae_Br4923          EDAGYISGAVIPVDGGLGMGH--------
                                    : :. :.*:     **