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CGAHRDRGYVYPVVTGGAQGLGLAIAERFVSEGARVVLGDVNLEATEAAAKQLGGGEVAVAVRCDVTKAD EVETLLQAALERFGGLDIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENKRGAIV NMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHVGVRVNAIAPGLIRSAMTEAMPQRIWDQKLAEV PMGRAGEPSEVASVALFLACDLSSYMTGTVLDVTGGRFI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3898 | fabG | - | 100% (250) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. ulcerans Agy99 | MUL_1491 | fabG1 | 1e-43 | 39.32% (234) | 3-oxoacyl- |
| M. ulcerans Agy99 | MUL_1037 | fabG3 | 2e-41 | 39.32% (234) | 20-beta-hydroxysteroid dehydrogenase FabG3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 1e-117 | 89.03% (237) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4369 | fabG | 1e-108 | 81.43% (237) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv1350 | fabG | 1e-117 | 89.03% (237) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-41 | 38.46% (234) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_2723c | - | 1e-44 | 38.46% (234) | 3-oxoacyl- |
| M. marinum M | MMAR_4033 | fabG | 1e-129 | 99.58% (237) | 3-oxoacyl- |
| M. avium 104 | MAV_1572 | - | 1e-117 | 88.61% (237) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2206 | fabG | 1e-112 | 84.81% (237) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_3693 | - | 1e-109 | 81.43% (237) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_1975 | fabG | 1e-109 | 83.12% (237) | 3-ketoacyl-(acyl-carrier-protein) reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4369|M.gilvum_PYR-GCK ----------------MSLLTG--QTAVITGGAQGLGFAIAQRFVDEGAR
Mvan_1975|M.vanbaalenii_PYR-1 ----------MRMGEQVSLLTG--QTAVITGGAQGLGFAIAQRFVEEGAR
TH_3693|M.thermoresistible__bu ----------------VSLLAG--QTAVVTGGARGLGYAIAERFIAEGAR
MSMEG_2206|M.smegmatis_MC2_155 ------------------MLTG--QTAVVTGGAQGLGLAIAKRFISEGAR
Mb1385|M.bovis_AF2122/97 ---------------MASLLNA--RTAVITGGAQGLGLAIGQRFVAEGAR
Rv1350|M.tuberculosis_H37Rv ---------------MASLLNA--RTAVITGGAQGLGLAIGQRFVAEGAR
MUL_3898|M.ulcerans_Agy99 --------------MCGAHRDRGYVYPVVTGGAQGLGLAIAERFVSEGAR
MMAR_4033|M.marinum_M --------------MSVSLLNG--QIAVVTGGAQGLGLAIAERFVSEGAR
MAV_1572|M.avium_104 ----------------MSLLSG--QTAVITGGAQGLGFAIAERFVAEGAR
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSR---SILVTGGNRGIGLAVARRLVADGHR
MAB_2723c|M.abscessus_ATCC_199 MTNA-------------EFVPR---SVLVTGGNRGIGLAVAQRLAADGHK
::*** :*:* *:..*: :* :
Mflv_4369|M.gilvum_PYR-GCK VVLGDVNLEATQEAAEKLGGADVAHAVRCDVTSSAEVDALVAAAVDTFGA
Mvan_1975|M.vanbaalenii_PYR-1 VVLGDVNLDATVAAAEKLGGEDVARAVRCDVTDSAEVDALIAAAVDGFGS
TH_3693|M.thermoresistible__bu VVIGDIDESATRAAADSLGGADVAVGMRCDVTRSDEVEALVGAAVKRFGS
MSMEG_2206|M.smegmatis_MC2_155 VVLGDLNSEATEAAVEELGGSEVAAAVRCDVTSSADVDALVQAAVERFGG
Mb1385|M.bovis_AF2122/97 VVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGG
Rv1350|M.tuberculosis_H37Rv VVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGG
MUL_3898|M.ulcerans_Agy99 VVLGDVNLEATEAAAKQLGGGEVAVAVRCDVTKADEVETLLQAALERFGG
MMAR_4033|M.marinum_M VVLGDVNLEATEAAAKQLGGGEVAVAVRCDVTKADEVETLLQTALERFGG
MAV_1572|M.avium_104 VVLGDVNLEATQTAAKQLGGDQVALAVRCDVTKSSEVETLIQTAVERFGG
MLBr_01807|M.leprae_Br4923 VAVTHR---ASVVPDWFFG-------VECDVTDNDAIGAAFKAVEEHQGP
MAB_2723c|M.abscessus_ATCC_199 VAVTHR---GSGAPEGLLG-------VQCDITDNDQIDAAFKEVEEKQGP
*.: . .: . :* :.**:* : . . . *
Mflv_4369|M.gilvum_PYR-GCK LDIMVNNAGITRDATMRKMTEDDFDKVIAVHLKGTWNGLRAAAAIMRENK
Mvan_1975|M.vanbaalenii_PYR-1 LDIMVNNAGITRDATMRKMTEEQFDQVIAVHLKGTWNGLRAAAAVMREQK
TH_3693|M.thermoresistible__bu LDVMVNNAGITRDATMRKMTEQQFDEVIAVHLKGTWNGLRAAAAIMREQK
MSMEG_2206|M.smegmatis_MC2_155 LDIMVNNAGITRDATLRKMTEEQFDQVIAVHLKGTWNGTKAAAAIMRENK
Mb1385|M.bovis_AF2122/97 LDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERK
Rv1350|M.tuberculosis_H37Rv LDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERK
MUL_3898|M.ulcerans_Agy99 LDIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENK
MMAR_4033|M.marinum_M LDIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENK
MAV_1572|M.avium_104 LDIMVNNAGITRDATMRKMTEEQFDQVIAVHLKGTWNGTRLAAAIMRENK
MLBr_01807|M.leprae_Br4923 VEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
MAB_2723c|M.abscessus_ATCC_199 VEVLVANAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKR
::::* ***** * : *:*::* :** .:* *.:. : *: * :.:
Mflv_4369|M.gilvum_PYR-GCK RGVIVNMSSISGKVGMIGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAI
Mvan_1975|M.vanbaalenii_PYR-1 RGAIVNMSSISGKVGMVGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAI
TH_3693|M.thermoresistible__bu RGAIVNMSSISGKVGMVGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAI
MSMEG_2206|M.smegmatis_MC2_155 RGAIVNMSSISGKVGLIGQTNYSAAKAGIVGMTKAAAKELAYLGVRVNAI
Mb1385|M.bovis_AF2122/97 RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAI
Rv1350|M.tuberculosis_H37Rv RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAI
MUL_3898|M.ulcerans_Agy99 RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHVGVRVNAI
MMAR_4033|M.marinum_M RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHVGVRVNAI
MAV_1572|M.avium_104 RGAIINMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAYLGVRVNAI
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
MAB_2723c|M.abscessus_ATCC_199 FGRLIFMGSVAGQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVV
* : *.*: * *: **:**:*:*:*::**::: ::**. .: .*.:
Mflv_4369|M.gilvum_PYR-GCK QPGLIRSAMTEAMPQRIWDSKVAEVPLGRAGEPDEVAKVALFLASDLSSY
Mvan_1975|M.vanbaalenii_PYR-1 QPGLIRSAMTEAMPQRIWDSKVAEVPMGRAGEPEEVANVALFLASDLSSY
TH_3693|M.thermoresistible__bu QPGLIRSAMTEAMPQRIWDEKLAEIPMGRAGEPEEVAKVALFLASDLSSY
MSMEG_2206|M.smegmatis_MC2_155 QPGLIRSAMTEAMPQRIWDEKLAEIPMGRAGEPDEVAKVALFLASDLSSY
Mb1385|M.bovis_AF2122/97 APGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSSY
Rv1350|M.tuberculosis_H37Rv APGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSSY
MUL_3898|M.ulcerans_Agy99 APGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVALFLACDLSSY
MMAR_4033|M.marinum_M APGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVALFLACDLSSY
MAV_1572|M.avium_104 APGLIRSAMTEAMPQRIWDSKVAEVPMGRAGEPSEVASVALFLASDMSSY
MLBr_01807|M.leprae_Br4923 APGFIDTEMTRAMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGY
MAB_2723c|M.abscessus_ATCC_199 APGFIDTDMTRELGEKHVETALTAIPMGRIGEPSEVAGVVSWLASPDAAY
**:* : **. : .: : : :*:** * .*:* .. :**. :.*
Mflv_4369|M.gilvum_PYR-GCK MTGTVLEVTGGRHL--
Mvan_1975|M.vanbaalenii_PYR-1 MTGTVLEVTGGRHL--
TH_3693|M.thermoresistible__bu MTGTVLEVTGGRHL--
MSMEG_2206|M.smegmatis_MC2_155 MTGTVLEVTGGRHV--
Mb1385|M.bovis_AF2122/97 MTGTVLDVTGGRFI--
Rv1350|M.tuberculosis_H37Rv MTGTVLDVTGGRFI--
MUL_3898|M.ulcerans_Agy99 MTGTVLDVTGGRFI--
MMAR_4033|M.marinum_M MTGTVLDVTGGRFI--
MAV_1572|M.avium_104 MTGTVMEITGGRHL--
MLBr_01807|M.leprae_Br4923 ISGAVIPVDGGLGMGH
MAB_2723c|M.abscessus_ATCC_199 VSGAVIPVDGGLGMGH
::*:*: : ** :