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M. marinum M MMAR_2869 (-)

annotation: short-chain type dehydrogenase/reductase
coordinates: 3475567 - 3476337
length: 256

VRYPDLAGKATIVTGAGAGIGLAIAERLAAEGAAVLCADIDGASAEQAAAKIGSGAVGYQVDVSAEEQVA
GMVEACVTSFGGLDKLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGGAIVNMS
SLAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLPAFVDTPMQQSAMAMFDEALGTGGANT
MIARLQGRMARPEEMASIVAFLLSDDSSMITGTTQIADGGTIAALW
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2869--100% (256)short-chain type dehydrogenase/reductase
M. marinum MMMAR_4765-2e-3939.06% (256) short chain dehydrogenase
M. marinum MMMAR_4033fabG4e-3937.50% (248) 3-oxoacyl-

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1976-1e-11277.73% (256) short-chain type dehydrogenase/reductase
M. gilvum PYR-GCKMflv_4505-2e-3935.46% (251) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1941-1e-11277.73% (256) short-chain type dehydrogenase/reductase
M. leprae Br4923MLBr_01807fabG13e-3031.98% (247) 3-oxoacyl-
M. abscessus ATCC 19977MAB_4680c-3e-3837.10% (248) putative short-chain dehydrogenase/reductase
M. avium 104MAV_5088fabG5e-4544.76% (248) 3-ketoacyl-(acyl-carrier-protein) reductase
M. smegmatis MC2 155MSMEG_2206fabG2e-4038.71% (248) 3-ketoacyl-(acyl-carrier-protein) reductase
M. thermoresistible (build 8)TH_3693-8e-4139.11% (248) PUTATIVE short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_2885-1e-13998.83% (256) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1Mvan_3999-1e-11378.74% (254) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4505|M.gilvum_PYR-GCK          -----------MTGR---LAGKVALISGAARGMGASHARVMAGHGAKVVC
MAB_4680c|M.abscessus_ATCC_199      -----------MNGNSALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
MMAR_2869|M.marinum_M               -----------MRYP--DLAGKATIVTGAGAGIGLAIAERLAAEGAAVLC
MUL_2885|M.ulcerans_Agy99           -----------MRYP--DLAGKATIVTGAGAGIGLAIAERLAAEGAAVLC
Mvan_3999|M.vanbaalenii_PYR-1       -----------MTYP--DLADKAVIVTGAAAGIGLAIAERLAAERCRVVC
Mb1976|M.bovis_AF2122/97            -----------MNHP--DLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Rv1941|M.tuberculosis_H37Rv         -----------MNHP--DLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
MSMEG_2206|M.smegmatis_MC2_155      -----------------MLTGQTAVVTGGAQGLGLAIAKRFISEGARVVL
TH_3693|M.thermoresistible__bu      -------------VS--LLAGQTAVVTGGARGLGYAIAERFIAEGARVVI
MAV_5088|M.avium_104                -----------MAES--LLLGKVAVVTGAGQGIGREIARALHRHGARVVL
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                      : .:  :::*.  *:*   :. :  .   *  

Mflv_4505|M.gilvum_PYR-GCK          GDILDSDGEAVAAELGDA---ARYVHLDVTSPDDWDRAVAAAVADFGGLD
MAB_4680c|M.abscessus_ATCC_199      ADVLDGDGRQLAAELGDA---ARFTHLDVTDAEQWRELIDTTLAGFGTIT
MMAR_2869|M.marinum_M               ADIDGASAEQAAAKIGSG---AVGYQVDVSAEEQVAGMVEACVTSFGGLD
MUL_2885|M.ulcerans_Agy99           ADIDGASAEQAAAKIGSG---AVGYQVDVSAEEQVAGMVEACVTSFGGLD
Mvan_3999|M.vanbaalenii_PYR-1       ADIDGAAADAAAAAIGNG---AVGYAVDVSDEPQVVGMVEACVAAFGGVD
Mb1976|M.bovis_AF2122/97            ADIDGDAADAAATKIGCG---AAACRVDVSDEQQIIAMVDACVAAFGGVD
Rv1941|M.tuberculosis_H37Rv         ADIDGDAADAAATKIGCG---AAACRVDVSDEQQIIAMVDACVAAFGGVD
MSMEG_2206|M.smegmatis_MC2_155      GDLNSEATEAAVEELGGS-EVAAAVRCDVTSSADVDALVQAAVERFGGLD
TH_3693|M.thermoresistible__bu      GDIDESATRAAADSLGGA-DVAVGMRCDVTRSDEVEALVGAAVKRFGSLD
MAV_5088|M.avium_104                ADLDGSAARSAAAQIDDSGANCTGLACDVTSEEQVGALVAGTVREHGGLD
MLBr_01807|M.leprae_Br4923          THRASVVPDWFFG-----------VECDVTDNDAIGAAFKAVEEHQGPVE
                                     .                         **:        .       * : 

Mflv_4505|M.gilvum_PYR-GCK          VLVNNAGILNIGTVEDYELSEWHRILDVNLTGVFLGIRAATPTMKAAGRG
MAB_4680c|M.abscessus_ATCC_199      GLVNNAGISSAAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHGCG
MMAR_2869|M.marinum_M               KLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGG
MUL_2885|M.ulcerans_Agy99           KLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGG
Mvan_3999|M.vanbaalenii_PYR-1       KLVANAGVVHFAPLTETTVDDFDRIIGINLRGAWLCTKHAAPRMAERGGG
Mb1976|M.bovis_AF2122/97            KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG
Rv1941|M.tuberculosis_H37Rv         KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG
MSMEG_2206|M.smegmatis_MC2_155      IMVNNAGITRDATLRKMTEEQFDQVIAVHLKGTWNGTKAAAAIMRENKRG
TH_3693|M.thermoresistible__bu      VMVNNAGITRDATMRKMTEQQFDEVIAVHLKGTWNGLRAAAAIMREQKRG
MAV_5088|M.avium_104                VFVNNAGITRDASLKRMTVADFDAVIAVHLRGTWLGVREAAAVMRERKTG
MLBr_01807|M.leprae_Br4923          VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG
                                     :* ***:     :      .:  :: ::* *.:   : .   *     *

Mflv_4505|M.gilvum_PYR-GCK          SIINIASIEGMAGTVGCHGYTATKFAVRGLTKSTALELGPFGIRVNSVHP
MAB_4680c|M.abscessus_ATCC_199      SIVNISSAAGLVGLALTSGYGASKWGVRGLSKVAAIELGRERIRVNSVHP
MMAR_2869|M.marinum_M               AIVNMSSLAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLP
MUL_2885|M.ulcerans_Agy99           AIVNMSSLAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLP
Mvan_3999|M.vanbaalenii_PYR-1       AIVNMSSLGGLVAAAGTAAYGMSKAGIIHLSRITAAEMRSANIRSNALLP
Mb1976|M.bovis_AF2122/97            AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP
Rv1941|M.tuberculosis_H37Rv         AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP
MSMEG_2206|M.smegmatis_MC2_155      AIVNMSSISGKVGLIGQTNYSAAKAGIVGMTKAAAKELAYLGVRVNAIQP
TH_3693|M.thermoresistible__bu      AIVNMSSISGKVGMVGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAIQP
MAV_5088|M.avium_104                SIVNMSSLSGKAGNPGQTNYSAAKAGIVGLTKAAAKELAHHNVRVNAIQP
MLBr_01807|M.leprae_Br4923          RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAP
                                      : :.*  *  .      *  :* .:  :::  : *:    :  * : *

Mflv_4505|M.gilvum_PYR-GCK          GLVKTPMADWV--------PEDIFQSALG----RIAQPHEVSNLVVYLAS
MAB_4680c|M.abscessus_ATCC_199      GVIYTPMTAKEGFREG---EGNMPIAAMG----RVGNADEVAGAVAYLLS
MMAR_2869|M.marinum_M               AFVDTPMQQSAMAMFDEALGTGGANTMIARLQGRMARPEEMASIVAFLLS
MUL_2885|M.ulcerans_Agy99           AFVDTPMQQSAMAMFDEVLGTGGANTMIARLQGRMARPEEMARIVAFLLP
Mvan_3999|M.vanbaalenii_PYR-1       AFVDTPMQQTAMTMFDEALGDGGAATMIGRLQGRMAGPAEMAGVVAFLLS
Mb1976|M.bovis_AF2122/97            AFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEMAGIVVFLLS
Rv1941|M.tuberculosis_H37Rv         AFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEMAGIVVFLLS
MSMEG_2206|M.smegmatis_MC2_155      GLIRSAMTE---AMPQRIWDEKLAEIPMG----RAGEPDEVAKVALFLAS
TH_3693|M.thermoresistible__bu      GLIRSAMTE---AMPQRIWDEKLAEIPMG----RAGEPEEVAKVALFLAS
MAV_5088|M.avium_104                GLIRTPMTA---AMPPDVFAEREAAVPMK----RAGEPEEVAGAVVFLAS
MLBr_01807|M.leprae_Br4923          GFIDTEMTR---AMDSKYQEAALQAIPLG----RIGAVEEIAGAVSFLAS
                                    ..: : *                    :     * .   *::  . :* .

Mflv_4505|M.gilvum_PYR-GCK          DESSYSTGAEFVVDGGTLAGLAHKDFSAVDVDQQPEWIT
MAB_4680c|M.abscessus_ATCC_199      DAASYVTGAELAVDGGWTAGPTLTTITGQ----------
MMAR_2869|M.marinum_M               DDSSMITGTTQIADGGTIAALW-----------------
MUL_2885|M.ulcerans_Agy99           DDSSMITGTTQIADGGTIAALW-----------------
Mvan_3999|M.vanbaalenii_PYR-1       DAASMVNGTAQLADGGTLAALW-----------------
Mb1976|M.bovis_AF2122/97            DDASMITGTTQIADGGTIAALW-----------------
Rv1941|M.tuberculosis_H37Rv         DDASMITGTTQIADGGTIAALW-----------------
MSMEG_2206|M.smegmatis_MC2_155      DLSSYMTGTVLEVTGGRHV--------------------
TH_3693|M.thermoresistible__bu      DLSSYMTGTVLEVTGGRHL--------------------
MAV_5088|M.avium_104                ELSSYITGTVLGVGGGRYM--------------------
MLBr_01807|M.leprae_Br4923          EDAGYISGAVIPVDGGLGMGH------------------
                                    : :.  .*:   . **