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VRYPDLAGKATIVTGAGAGIGLAIAERLAAEGAAVLCADIDGASAEQAAAKIGSGAVGYQVDVSAEEQVA GMVEACVTSFGGLDKLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGGAIVNMS SLAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLPAFVDTPMQQSAMAMFDEALGTGGANT MIARLQGRMARPEEMASIVAFLLSDDSSMITGTTQIADGGTIAALW
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2869 | - | - | 100% (256) | short-chain type dehydrogenase/reductase |
M. marinum M | MMAR_4765 | - | 2e-39 | 39.06% (256) | short chain dehydrogenase |
M. marinum M | MMAR_4033 | fabG | 4e-39 | 37.50% (248) | 3-oxoacyl- |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1976 | - | 1e-112 | 77.73% (256) | short-chain type dehydrogenase/reductase |
M. gilvum PYR-GCK | Mflv_4505 | - | 2e-39 | 35.46% (251) | short-chain dehydrogenase/reductase SDR |
M. tuberculosis H37Rv | Rv1941 | - | 1e-112 | 77.73% (256) | short-chain type dehydrogenase/reductase |
M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-30 | 31.98% (247) | 3-oxoacyl- |
M. abscessus ATCC 19977 | MAB_4680c | - | 3e-38 | 37.10% (248) | putative short-chain dehydrogenase/reductase |
M. avium 104 | MAV_5088 | fabG | 5e-45 | 44.76% (248) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. smegmatis MC2 155 | MSMEG_2206 | fabG | 2e-40 | 38.71% (248) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. thermoresistible (build 8) | TH_3693 | - | 8e-41 | 39.11% (248) | PUTATIVE short-chain dehydrogenase/reductase SDR |
M. ulcerans Agy99 | MUL_2885 | - | 1e-139 | 98.83% (256) | short-chain type dehydrogenase/reductase |
M. vanbaalenii PYR-1 | Mvan_3999 | - | 1e-113 | 78.74% (254) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4505|M.gilvum_PYR-GCK -----------MTGR---LAGKVALISGAARGMGASHARVMAGHGAKVVC MAB_4680c|M.abscessus_ATCC_199 -----------MNGNSALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI MMAR_2869|M.marinum_M -----------MRYP--DLAGKATIVTGAGAGIGLAIAERLAAEGAAVLC MUL_2885|M.ulcerans_Agy99 -----------MRYP--DLAGKATIVTGAGAGIGLAIAERLAAEGAAVLC Mvan_3999|M.vanbaalenii_PYR-1 -----------MTYP--DLADKAVIVTGAAAGIGLAIAERLAAERCRVVC Mb1976|M.bovis_AF2122/97 -----------MNHP--DLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC Rv1941|M.tuberculosis_H37Rv -----------MNHP--DLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC MSMEG_2206|M.smegmatis_MC2_155 -----------------MLTGQTAVVTGGAQGLGLAIAKRFISEGARVVL TH_3693|M.thermoresistible__bu -------------VS--LLAGQTAVVTGGARGLGYAIAERFIAEGARVVI MAV_5088|M.avium_104 -----------MAES--LLLGKVAVVTGAGQGIGREIARALHRHGARVVL MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV : .: :::*. *:* :. : . * Mflv_4505|M.gilvum_PYR-GCK GDILDSDGEAVAAELGDA---ARYVHLDVTSPDDWDRAVAAAVADFGGLD MAB_4680c|M.abscessus_ATCC_199 ADVLDGDGRQLAAELGDA---ARFTHLDVTDAEQWRELIDTTLAGFGTIT MMAR_2869|M.marinum_M ADIDGASAEQAAAKIGSG---AVGYQVDVSAEEQVAGMVEACVTSFGGLD MUL_2885|M.ulcerans_Agy99 ADIDGASAEQAAAKIGSG---AVGYQVDVSAEEQVAGMVEACVTSFGGLD Mvan_3999|M.vanbaalenii_PYR-1 ADIDGAAADAAAAAIGNG---AVGYAVDVSDEPQVVGMVEACVAAFGGVD Mb1976|M.bovis_AF2122/97 ADIDGDAADAAATKIGCG---AAACRVDVSDEQQIIAMVDACVAAFGGVD Rv1941|M.tuberculosis_H37Rv ADIDGDAADAAATKIGCG---AAACRVDVSDEQQIIAMVDACVAAFGGVD MSMEG_2206|M.smegmatis_MC2_155 GDLNSEATEAAVEELGGS-EVAAAVRCDVTSSADVDALVQAAVERFGGLD TH_3693|M.thermoresistible__bu GDIDESATRAAADSLGGA-DVAVGMRCDVTRSDEVEALVGAAVKRFGSLD MAV_5088|M.avium_104 ADLDGSAARSAAAQIDDSGANCTGLACDVTSEEQVGALVAGTVREHGGLD MLBr_01807|M.leprae_Br4923 THRASVVPDWFFG-----------VECDVTDNDAIGAAFKAVEEHQGPVE . **: . * : Mflv_4505|M.gilvum_PYR-GCK VLVNNAGILNIGTVEDYELSEWHRILDVNLTGVFLGIRAATPTMKAAGRG MAB_4680c|M.abscessus_ATCC_199 GLVNNAGISSAAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHGCG MMAR_2869|M.marinum_M KLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGG MUL_2885|M.ulcerans_Agy99 KLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGG Mvan_3999|M.vanbaalenii_PYR-1 KLVANAGVVHFAPLTETTVDDFDRIIGINLRGAWLCTKHAAPRMAERGGG Mb1976|M.bovis_AF2122/97 KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG Rv1941|M.tuberculosis_H37Rv KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG MSMEG_2206|M.smegmatis_MC2_155 IMVNNAGITRDATLRKMTEEQFDQVIAVHLKGTWNGTKAAAAIMRENKRG TH_3693|M.thermoresistible__bu VMVNNAGITRDATMRKMTEQQFDEVIAVHLKGTWNGLRAAAAIMREQKRG MAV_5088|M.avium_104 VFVNNAGITRDASLKRMTVADFDAVIAVHLRGTWLGVREAAAVMRERKTG MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG :* ***: : .: :: ::* *.: : . * * Mflv_4505|M.gilvum_PYR-GCK SIINIASIEGMAGTVGCHGYTATKFAVRGLTKSTALELGPFGIRVNSVHP MAB_4680c|M.abscessus_ATCC_199 SIVNISSAAGLVGLALTSGYGASKWGVRGLSKVAAIELGRERIRVNSVHP MMAR_2869|M.marinum_M AIVNMSSLAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLP MUL_2885|M.ulcerans_Agy99 AIVNMSSLAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLP Mvan_3999|M.vanbaalenii_PYR-1 AIVNMSSLGGLVAAAGTAAYGMSKAGIIHLSRITAAEMRSANIRSNALLP Mb1976|M.bovis_AF2122/97 AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP Rv1941|M.tuberculosis_H37Rv AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP MSMEG_2206|M.smegmatis_MC2_155 AIVNMSSISGKVGLIGQTNYSAAKAGIVGMTKAAAKELAYLGVRVNAIQP TH_3693|M.thermoresistible__bu AIVNMSSISGKVGMVGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAIQP MAV_5088|M.avium_104 SIVNMSSLSGKAGNPGQTNYSAAKAGIVGLTKAAAKELAHHNVRVNAIQP MLBr_01807|M.leprae_Br4923 RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAP : :.* * . * :* .: ::: : *: : * : * Mflv_4505|M.gilvum_PYR-GCK GLVKTPMADWV--------PEDIFQSALG----RIAQPHEVSNLVVYLAS MAB_4680c|M.abscessus_ATCC_199 GVIYTPMTAKEGFREG---EGNMPIAAMG----RVGNADEVAGAVAYLLS MMAR_2869|M.marinum_M AFVDTPMQQSAMAMFDEALGTGGANTMIARLQGRMARPEEMASIVAFLLS MUL_2885|M.ulcerans_Agy99 AFVDTPMQQSAMAMFDEVLGTGGANTMIARLQGRMARPEEMARIVAFLLP Mvan_3999|M.vanbaalenii_PYR-1 AFVDTPMQQTAMTMFDEALGDGGAATMIGRLQGRMAGPAEMAGVVAFLLS Mb1976|M.bovis_AF2122/97 AFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEMAGIVVFLLS Rv1941|M.tuberculosis_H37Rv AFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEMAGIVVFLLS MSMEG_2206|M.smegmatis_MC2_155 GLIRSAMTE---AMPQRIWDEKLAEIPMG----RAGEPDEVAKVALFLAS TH_3693|M.thermoresistible__bu GLIRSAMTE---AMPQRIWDEKLAEIPMG----RAGEPEEVAKVALFLAS MAV_5088|M.avium_104 GLIRTPMTA---AMPPDVFAEREAAVPMK----RAGEPEEVAGAVVFLAS MLBr_01807|M.leprae_Br4923 GFIDTEMTR---AMDSKYQEAALQAIPLG----RIGAVEEIAGAVSFLAS ..: : * : * . *:: . :* . Mflv_4505|M.gilvum_PYR-GCK DESSYSTGAEFVVDGGTLAGLAHKDFSAVDVDQQPEWIT MAB_4680c|M.abscessus_ATCC_199 DAASYVTGAELAVDGGWTAGPTLTTITGQ---------- MMAR_2869|M.marinum_M DDSSMITGTTQIADGGTIAALW----------------- MUL_2885|M.ulcerans_Agy99 DDSSMITGTTQIADGGTIAALW----------------- Mvan_3999|M.vanbaalenii_PYR-1 DAASMVNGTAQLADGGTLAALW----------------- Mb1976|M.bovis_AF2122/97 DDASMITGTTQIADGGTIAALW----------------- Rv1941|M.tuberculosis_H37Rv DDASMITGTTQIADGGTIAALW----------------- MSMEG_2206|M.smegmatis_MC2_155 DLSSYMTGTVLEVTGGRHV-------------------- TH_3693|M.thermoresistible__bu DLSSYMTGTVLEVTGGRHL-------------------- MAV_5088|M.avium_104 ELSSYITGTVLGVGGGRYM-------------------- MLBr_01807|M.leprae_Br4923 EDAGYISGAVIPVDGGLGMGH------------------ : :. .*: . **