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KRLRRLAACIAAAGLTATAGCAGAGTLGATDQTVTIAMVSNSQMTDARELSSRFEAENPDIKLRFVTLSE NQARAKITASTAMGGGEFDVVMISNYETPQWAENGWLVDLSDYARNTPGYDEDDFIPSLKDSLSYQGDMY SVPFYGESSFLMYRKDLFEQAGIEMPRTPTWQQVADAAAELNGPDMVGICLRGKPGWGEVLAPLDTVINT FGGRWFDMDWNAQLTSPEVRKAVQFYVDTVREYGEPGASAAGFGECATQFAQGRAAMWYDATSAVSTVED PASSNVVGKVGYAMAPTMEKPNSGWLYTWALGIPKSSDKPDAAWKFISWMTDKDYIHLVGEELGWARVPP GSRLSTYEIPEYKEASAAFGQVTLDSIEGADPAKPTVQPVPYTGVQFLAIPEFQDLGTRVSQQISAAIAG QKSVDEALEQAQKYAEVVGRSYQEKP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_5574 | - | - | 100% (447) | substrate binding protein |
M. smegmatis MC2 155 | MSMEG_3111 | - | 1e-32 | 27.03% (444) | extracellular solute-binding protein, family protein 1 |
M. smegmatis MC2 155 | MSMEG_0553 | - | 2e-20 | 26.20% (439) | sugar ABC transporter, substrate-binding protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2857c | ugpB | 3e-14 | 24.93% (361) | sn-glycerol-3-phosphate-binding lipoprotein UGPB |
M. gilvum PYR-GCK | Mflv_3775 | - | 1e-36 | 27.75% (436) | extracellular solute-binding protein |
M. tuberculosis H37Rv | Rv2833c | ugpB | 3e-15 | 25.21% (361) | sn-glycerol-3-phosphate-binding lipoprotein UGPB |
M. leprae Br4923 | MLBr_01427 | - | 6e-18 | 25.56% (360) | putative ABC-transport lipoprotein |
M. abscessus ATCC 19977 | MAB_1715c | - | 5e-11 | 22.17% (415) | sugar ABC transporter, sugar-binding protein |
M. marinum M | MMAR_3014 | - | 4e-16 | 26.49% (370) | sugar-binding lipoprotein |
M. avium 104 | MAV_2476 | - | 5e-17 | 26.40% (356) | sugar ABC transporter, sugar-binding protein |
M. thermoresistible (build 8) | TH_2011 | - | 0.0 | 80.41% (444) | substrate binding protein |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_2624 | - | 2e-34 | 26.80% (444) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_5574|M.smegmatis_MC2_155 --------------MKR--LRRLAACIAAAGLTATAGCAGAG-------- TH_2011|M.thermoresistible__bu --------------VRRTPIRAVLAAVAAVCLTLTG-CAGAG-------- Mflv_3775|M.gilvum_PYR-GCK MRFAQIPT-ARRGGK--TARSAVLALLAVLALVLSA-CAGSGGPEQAEST Mvan_2624|M.vanbaalenii_PYR-1 MRITQWPTSGRRSGRPGTAFSAVMALVAVLALVLTG-CAGSGGPEQAEAT Mb2857c|M.bovis_AF2122/97 ---------------MDPLNRRQFLALAAAAAGVTAGCAGMGG------- Rv2833c|M.tuberculosis_H37Rv ---------------MDPLNRRQFLALAAAAAGVTAGCAGMGG------- MLBr_01427|M.leprae_Br4923 -------------MHGKLFGRR---SLLRGAGALTAAALAPGA------- MMAR_3014|M.marinum_M -------------MFDKPLRRR---ELLRGAGLLTAAALAPVA------- MAV_2476|M.avium_104 -------------MLDRPFGRR---SLLRGAGALSAAALAPWS------- MAB_1715c|M.abscessus_ATCC_199 ----------------MKASTRAALTLALVALLLFGVAAWLGIP------ : . . MSMEG_5574|M.smegmatis_MC2_155 ----TLGATDQTVTIAMVSNSQMTDARELSSRFEAENPDIKLRFVTLSEN TH_2011|M.thermoresistible__bu ----TLGSSGNTVTIALVSNSQMSDAQRLAPHFEAANPDIRLKFVTLSEN Mflv_3775|M.gilvum_PYR-GCK GSGEVSADTSGTVRILMENVPDTDIVKSMVADFNAEYPGVEINIESLTFD Mvan_2624|M.vanbaalenii_PYR-1 GTGEVSTDVSGTVRILMENVPDTDIVKSMVADFNKEYPGVEINIESLTFD Mb2857c|M.bovis_AF2122/97 -GGSVKSGSGPIDFWSSHPGQSSAAERELIGRFQDRFPTLSVKLIDAGKD Rv2833c|M.tuberculosis_H37Rv -GGSVKSGSGPIDFWSSHPGQSSAAERELIGRFQDRFPTLSVKLIDAGKD MLBr_01427|M.leprae_Br4923 -VGCSSDDD-ALTFFFAANPEETNARMRIVGEFQRDHPDIKVRAVLSGPG MMAR_3014|M.marinum_M -AGCASDDD-ALTFFFAANPEEADARIRVVDAFGRSHPDIKVRTLLSGPG MAV_2476|M.avium_104 -AGCGSDDDGALTFFFAANPEERDARMRIIDEFARRHPDIKVRAVLSGPG MAB_1715c|M.abscessus_ATCC_199 ----TTPHGKTVVTVRVWDQQVAEAYRGSFDEFSRRNPDIQVAVTVTSYA * * : : MSMEG_5574|M.smegmatis_MC2_155 -QARAKITASTAMGGGEFDVVMISNYETPQWAENGWLVDLSDYARNTP-- TH_2011|M.thermoresistible__bu -QARAKITASTAMGGGEFDVVMISNYETPQWAADGWLVNLSDYARQTP-- Mflv_3775|M.gilvum_PYR-GCK -QMRDKLVSSFQSSSPAYDLIVVDNPWMVDFANAKFLQPLDARIDSTP-- Mvan_2624|M.vanbaalenii_PYR-1 -QMRDKLVSSFQSSSPTYDLIVVDNPWMVDFANAKFLQPLDARIDSTP-- Mb2857c|M.bovis_AF2122/97 YDEVAQKFNAALIGTDVPDVVLLDDRWWFHFALIGVLTALDDLFGQVG-- Rv2833c|M.tuberculosis_H37Rv YDEVAQKFNAALIGTDVPDVVLLDDRWWFHFALSGVLTALDDLFGQVG-- MLBr_01427|M.leprae_Br4923 ---VMQQLSTFCAGGKCPDVLMAWDLTYAELADRGVLLDLNTLLGQDKAF MMAR_3014|M.marinum_M ---ALQQISTFCAGGKCPDVLMAWELSYAELADRGVFLDLNTMLARDQKF MAV_2476|M.avium_104 ---VMQQLSTFCVGGRCPDVLMAWELSYAELADRGVLLDLGPLLARDKAF MAB_1715c|M.abscessus_ATCC_199 --SYFNSLRTDVAGHGADDIFWLSNAYLSDYADTGNLVPVEPRADWDP-- : : . *:. : . * : : MSMEG_5574|M.smegmatis_MC2_155 -GYDEDDFIPSLKDSLSYQGDMYSVPFYGES-SFLMYRKDLFEQAGIEMP TH_2011|M.thermoresistible__bu -GYDEDDFIPSIRESLSYEGDMYAVPFYGES-SFLMYRKDLFEKSGIDMP Mflv_3775|M.gilvum_PYR-GCK -DYDAGDFFTPLTDITTVDGTRYGVPFYNYA-LGYLYNADDLAAANQQVP Mvan_2624|M.vanbaalenii_PYR-1 -DYDAADFFKPLTDITTVDGARYGVPFYNYA-LGYLYNADDLTAANQQVP Mb2857c|M.bovis_AF2122/97 --VDTTDYVDSLLADYEFNGRHYAVPYARST-PLFYYNKAAWQQAGLPD- Rv2833c|M.tuberculosis_H37Rv --VDTTDYVDSLLADYEFNGRHYAVPYARST-PLFYYNKAAWQQAGLPD- MLBr_01427|M.leprae_Br4923 AAELKSDSIEPLYETFTFNGGQYAFPEQWSG-NYLFYNKQLFTNAGVQPP MMAR_3014|M.marinum_M ADELAADSIGALYDTFAYNGGQYAFPEQWSG-NFLFYNRGLFADGGVPPP MAV_2476|M.avium_104 AQQLQADSIPALYETFTFNGKQYALPEQWSG-NYLFYNKRLFDEAGVPSP MAB_1715c|M.abscessus_ATCC_199 ----------SVVAQFTRDGKLWGVPQLSDAGIALYYNKNLLDAAQVDPA .: :* :..* *. . MSMEG_5574|M.smegmatis_MC2_155 R-----TPTWQQVADAAAELNGPDMVGICLRGKPGWGEVLAPLDTVINTF TH_2011|M.thermoresistible__bu H-----NPTWQQVADAAAALDTPDMAGICLRGKPGWGEVLAPLDTVINTF Mflv_3775|M.gilvum_PYR-GCK -------TTLDELVSTSKALKSGDRAGIAMQPQRGY-KIFEEWGNWLFAA Mvan_2624|M.vanbaalenii_PYR-1 -------TTLDELVSTSKALKSGDRAGIAMQPQRGY-KIFEEWGNWLFAA Mb2857c|M.bovis_AF2122/97 ----RGLQSWSEFDEWGPELQRVVGAGRSAHG-----WANADLISWTFQG Rv2833c|M.tuberculosis_H37Rv ----RGPQSWSEFDEWGPELQRVVGAGRSAHG-----WANADLISWTFQG MLBr_01427|M.leprae_Br4923 PCTWEQPWSFTEFLDTARALTKRDSSGRVTQWGFVNTWLSYYTAGLFALN MMAR_3014|M.marinum_M PTSWDQPWSFAEFLDTARALTKRDGAGRVTQWGFVDTFVPPLSAGLFALN MAV_2476|M.avium_104 PTAWERPWDFSEFLDTARALTKRDASGRAAQYGFVNTWGSYYSAGLFAMN MAB_1715c|M.abscessus_ATCC_199 ELAELRWDPDPEVDTLRPMLHRLTAPG-----HWGYNAANDLQGIYLNYL :. * * MSMEG_5574|M.smegmatis_MC2_155 G----GRWFDMDWNAQLTSPEVRKAVQFYVDTVREYGEPGASAAG---FG TH_2011|M.thermoresistible__bu G----GRWYDMDWNAQLDSPEVEEAVSFYVNLVRDHGEPGPATSG---FG Mflv_3775|M.gilvum_PYR-GCK G----GSIYDADGKITLNTPEAKRALEAYIDTYNTAAPANSLSWG---MD Mvan_2624|M.vanbaalenii_PYR-1 G----GSIYDADGKITLNTPEAKRALEAYIDTYNTAAPANSLSWG---MD Mb2857c|M.bovis_AF2122/97 PNWAFGGAYSDKWTLTLTEPATIAAGNFYRNSIHGKGYAAVAN------- Rv2833c|M.tuberculosis_H37Rv PNWAFGGAYSDKWTLTLTEPATIAAGNFYRNSIHGKGYAAVAN------- MLBr_01427|M.leprae_Br4923 NGVPWSNPRMNPTHLNFDDDAFIEAVQFYCDLTNKYQVAPDASEQQ--WM MMAR_3014|M.marinum_M NGVPWSTPRMNPTHLNFDDDAFIEAVQFYADLSAKHQVAPTASELQ--SI MAV_2476|M.avium_104 NGVPWSDPRLNPTHFNFDNAAFQEAVQFYADLANKYRVAPNASETQ--SM MAB_1715c|M.abscessus_ATCC_199 G--SAGAVFQADDKFAFAKPRAEMAFTYLVDLINVDRVAPSAADTNDNND . : * : . MSMEG_5574|M.smegmatis_MC2_155 ECATQFAQGRAAMWYDATSAVSTVEDPASSNVVGKVGYAMAPTMEKP--- TH_2011|M.thermoresistible__bu ECATQFAQGRAAMWYDATSAVSVLEDPAQSNVVGKVGYALAPTVVKA--- Mflv_3775|M.gilvum_PYR-GCK EAQRSVSANQSASMINYNWQLPALNEPGSGPAAGKIKLATIPGGKQ---- Mvan_2624|M.vanbaalenii_PYR-1 EAQRSVSANQAASMINYNWQLPALNEPGSGPAAGKIKLATIPGGKQ---- Mb2857c|M.bovis_AF2122/97 DIANEFATGILASAVASTGSLPGITASAR-FDFGAAPLPTGPDAAP---- Rv2833c|M.tuberculosis_H37Rv DIANEFATGILASAVASTGSLAGITASAR-FDFGAAPLPTGPDAAP---- MLBr_01427|M.leprae_Br4923 ATADLFSLGKAAIALGGHWRYQTFMRAEG-LDFDVTSLPIGPSAGTVPAT MMAR_3014|M.marinum_M ATTDLFSLGKAAMALGGHWRYQTFDRADG-LEFDVTALPLGPNG------ MAV_2476|M.avium_104 STPNLFAVGRAAMALGGHWRYQTYLRAEG-LDFDVAPLPVGPAVGK---- MAB_1715c|M.abscessus_ATCC_199 FSRNQFLQGRMALFQSGTYNLAQIQANAT-FPWDVAMMPAGPQGRVS--- . . * . . * MSMEG_5574|M.smegmatis_MC2_155 ---NSGWLYTWALGIPK--SSDKPDAAWKFISWMTDKDYIHLVGEELGWA TH_2011|M.thermoresistible__bu ---DAGWLYTWALGIPA--SSDNKDSAWKFISWMTDKNYIRLVGEELGWA Mflv_3775|M.gilvum_PYR-GCK ------VLGSWSWAIPA--NSATPDAAWAFVSWITAK-----PNDVVRTE Mvan_2624|M.vanbaalenii_PYR-1 ------VLGSWSWAIPA--NSATPDAAWAFVSWITAK-----PNDVVRTE Mb2857c|M.bovis_AF2122/97 ---ACP-TGGAGLAIPAKLSEERKVNALKFIAFVTNPTNTAYFSQQTGYL Rv2833c|M.tuberculosis_H37Rv ---ACP-TGGAGLAIPAKLSEERKVNALKFIAFVTNPTNTAYFSQQTGYL MLBr_01427|M.leprae_Br4923 RSGACSDIGATGLAIAA--SSSRKEQAWEFVKFATGPAGQALIGESCLFV MMAR_3014|M.marinum_M -RAACSNIGATGLAIAA--SSARKEQAWEFVKFATGPAGQALIGETDLFV MAV_2476|M.avium_104 GQPACSDIGATGLAISS--SSPRKEQAWEFVKFATGPVGQALIGESCLFV MAB_1715c|M.abscessus_ATCC_199 --------VTNGIVAAANSSSPHPDAVHKVLAWMGSTDGNSFLGRSGSAI . . .. . .: : . MSMEG_5574|M.smegmatis_MC2_155 RVPPGSRLSTYEIPEYKEASAAFGQVTLDSIEGADPAKPTVQPVPYTGVQ TH_2011|M.thermoresistible__bu RVPPGNRLSTYQIPEYQQASEAFGQVTLESLENADTQHPTVQPVPYTGVQ Mflv_3775|M.gilvum_PYR-GCK KGGAAIRKSTLQNPAVLQG--QFGEEYYRTVEQLLADAAPLTQGPSG--- Mvan_2624|M.vanbaalenii_PYR-1 KGGAAIRQSTLQDPAVLGG--QFGEEYYRTVEQLLANAAPLTQGPSG--- Mb2857c|M.bovis_AF2122/97 PVRKSAVDDASERHYLADNPRARVALDQLPHTRTQDYARVFLP------- Rv2833c|M.tuberculosis_H37Rv PVRKSAVDDASERHYLADNPRARVALDQLPHTRTQDYARVFLP------- MLBr_01427|M.leprae_Br4923 PVLQSAIYST----GFAKAHNRVANLAVLTGGPVHSAGLPITP------- MMAR_3014|M.marinum_M PVLGSALNSA----GFAKAHRRVDNLAVLTAGPGHSQGLPITP------- MAV_2476|M.avium_104 PVLRSALKSD----GFARAHRRVGNLGVLTDGPAFSQGLPITP------- MAB_1715c|M.abscessus_ATCC_199 PAVLSARAPYFQYWADKGVDVSPFFEVLRGQQIAAPGGQGFGAG------ . . MSMEG_5574|M.smegmatis_MC2_155 FLAIPEFQDLGTRVSQQISAAIAGQKSVDEALEQAQKYAEVVGRSYQEKP TH_2011|M.thermoresistible__bu FLAIPEFQDLGTRVSQQISAAIAGQKSVKDALAQAQKYAQVVGKTYQEKP Mflv_3775|M.gilvum_PYR-GCK -------EEMIQAVGTALNEAVAGEKSVDDALATAQAEAEKIQG------ Mvan_2624|M.vanbaalenii_PYR-1 -------EEMIQAVGTELNEAVAGKKSVDDALAAAQAEAEKIQG------ Mb2857c|M.bovis_AF2122/97 -----GGDRIISAGLESIG--LRGADVTKTFTNIQKRLQVILDRQIMRKL Rv2833c|M.tuberculosis_H37Rv -----GGDRIISAGLESIG--LRGADVTKTFTNIQKRLQVILDRQIMRKL MLBr_01427|M.leprae_Br4923 -----AWEKINALMDRNFGPVLRGVRPATSLAGLARAVDEVLNSP----- MMAR_3014|M.marinum_M -----AWPKVHALMDRNFGPVLRGSRPATSLIGMSRALDEVLRSP----- MAV_2476|M.avium_104 -----AWEKVNALMDRNFGPILRGSRPATSLAGLSRSVDEVLRSP----- MAB_1715c|M.abscessus_ATCC_199 ----------FAALKPYFAEMFLGRLDVREALQQAQRAANRALER----- : . * . : MSMEG_5574|M.smegmatis_MC2_155 ---- TH_2011|M.thermoresistible__bu ---- Mflv_3775|M.gilvum_PYR-GCK ---- Mvan_2624|M.vanbaalenii_PYR-1 ---- Mb2857c|M.bovis_AF2122/97 AGHG Rv2833c|M.tuberculosis_H37Rv AGHG MLBr_01427|M.leprae_Br4923 ---- MMAR_3014|M.marinum_M ---- MAV_2476|M.avium_104 ---- MAB_1715c|M.abscessus_ATCC_199 ----