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M. tuberculosis H37Rv Rv2833c (ugpB)

annotation: PROBABLE Sn-GLYCEROL-3-PHOSPHATE-BINDING LIPOPROTEIN UGPB
coordinates: 3139174 - 3140484
length: 436

DPLNRRQFLALAAAAAGVTAGCAGMGGGGSVKSGSGPIDFWSSHPGQSSAAERELIGRFQDRFPTLSVKL
IDAGKDYDEVAQKFNAALIGTDVPDVVLLDDRWWFHFALSGVLTALDDLFGQVGVDTTDYVDSLLADYEF
NGRHYAVPYARSTPLFYYNKAAWQQAGLPDRGPQSWSEFDEWGPELQRVVGAGRSAHGWANADLISWTFQ
GPNWAFGGAYSDKWTLTLTEPATIAAGNFYRNSIHGKGYAAVANDIANEFATGILASAVASTGSLAGITA
SARFDFGAAPLPTGPDAAPACPTGGAGLAIPAKLSEERKVNALKFIAFVTNPTNTAYFSQQTGYLPVRKS
AVDDASERHYLADNPRARVALDQLPHTRTQDYARVFLPGGDRIISAGLESIGLRGADVTKTFTNIQKRLQ
VILDRQIMRKLAGHG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2833cugpB-100% (436)PROBABLE Sn-GLYCEROL-3-PHOSPHATE-BINDING LIPOPROTEIN UGPB
M. tuberculosis H37RvRv2041c-9e-2025.74% (373) sugar-binding lipoprotein
M. tuberculosis H37RvRv2318uspC5e-0720.99% (443) periplasmic sugar-binding lipoprotein UspC

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2857cugpB0.099.31% (436) sn-glycerol-3-phosphate-binding lipoprotein UGPB
M. gilvum PYR-GCK-----
M. leprae Br4923MLBr_01427-1e-2026.88% (372) putative ABC-transport lipoprotein
M. abscessus ATCC 19977-----
M. marinum MMMAR_1900-0.075.97% (437) ABC-type sugar transport protein
M. avium 104MAV_2476-2e-2028.20% (383) sugar ABC transporter, sugar-binding protein
M. smegmatis MC2 155MSMEG_5574-4e-1525.21% (361) substrate binding protein
M. thermoresistible (build 8)TH_2011-2e-1524.52% (363) substrate binding protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_01427|M.leprae_Br4923          MHGKLFGRRSLLRG---AGALTAAALAPGAVGCSSDDD-ALTFFFAANPE
MAV_2476|M.avium_104                MLDRPFGRRSLLRG---AGALSAAALAPWSAGCGSDDDGALTFFFAANPE
Rv2833c|M.tuberculosis_H37Rv        -MDPLNRRQFLALA-AAAAGVTAGCAGMGGGGSVKSGSGPIDFWSSHPGQ
Mb2857c|M.bovis_AF2122/97           -MDPLNRRQFLALA-AAAAGVTAGCAGMGGGGSVKSGSGPIDFWSSHPGQ
MMAR_1900|M.marinum_M               -MNSMHRRRFLSLASAAAAGVTAGCAGITNNVSIKSGPGPISFWSNHPGQ
MSMEG_5574|M.smegmatis_MC2_155      -MKR--LRRLAACIAAAGLTATAGCAGAGTLGAT---DQTVTIAMVSNSQ
TH_2011|M.thermoresistible__bu      -VRRTPIRAVLAAVAAVCLTLTG-CAGAGTLGSS---GNTVTIALVSNSQ
                                           *             :. . .     .      .: :      :

MLBr_01427|M.leprae_Br4923          ETNARMRIVGEFQRDHPDIKVRAVLSGPG---VMQQLSTFCAGGKCPDVL
MAV_2476|M.avium_104                ERDARMRIIDEFARRHPDIKVRAVLSGPG---VMQQLSTFCVGGRCPDVL
Rv2833c|M.tuberculosis_H37Rv        SSAAERELIGRFQDRFPTLSVKLIDAGKDYDEVAQKFNAALIGTDVPDVV
Mb2857c|M.bovis_AF2122/97           SSAAERELIGRFQDRFPTLSVKLIDAGKDYDEVAQKFNAALIGTDVPDVV
MMAR_1900|M.marinum_M               SSGVEKVLIDRFQQQFPGLSVKLVDAGMDYDEVAEKFNAALIGDDVPDVV
MSMEG_5574|M.smegmatis_MC2_155      MTDAR-ELSSRFEAENPDIKLRFVTLSEN-QARAKITASTAMGGGEFDVV
TH_2011|M.thermoresistible__bu      MSDAQ-RLAPHFEAANPDIRLKFVTLSEN-QARAKITASTAMGGGEFDVV
                                       ..  :  .*    * : :: :  . .     :   :   *    **:

MLBr_01427|M.leprae_Br4923          MAWDLTYAELADRGVLLDLNTLLGQDKAFAAELKSDSIEPLYETFTFNGG
MAV_2476|M.avium_104                MAWELSYAELADRGVLLDLGPLLARDKAFAQQLQADSIPALYETFTFNGK
Rv2833c|M.tuberculosis_H37Rv        LLDDRWWFHFALSGVLTALDDLFG----QVGVDTTDYVDSLLADYEFNGR
Mb2857c|M.bovis_AF2122/97           LLDDRWWFHFALIGVLTALDDLFG----QVGVDTTDYVDSLLADYEFNGR
MMAR_1900|M.marinum_M               VLDDIWWFHFALSGVISPLDKLFR----QIGVDTSDYVDTLLADYEFNGR
MSMEG_5574|M.smegmatis_MC2_155      MISNYETPQWAENGWLVDLSDYAR---NTPGYDEDDFIPSLKDSLSYQGD
TH_2011|M.thermoresistible__bu      MISNYETPQWAADGWLVNLSDYAR---QTPGYDEDDFIPSIRESLSYEGD
                                    :  :    . *  * :  *.               * : .:     ::* 

MLBr_01427|M.leprae_Br4923          QYAFPEQWSGNYLFYNKQLFTNAGVQPPPCTWEQPWSFTEFLDTARALTK
MAV_2476|M.avium_104                QYALPEQWSGNYLFYNKRLFDEAGVPSPPTAWERPWDFSEFLDTARALTK
Rv2833c|M.tuberculosis_H37Rv        HYAVPYARSTPLFYYNKAAWQQAGLPD-----RGPQSWSEFDEWGPELQR
Mb2857c|M.bovis_AF2122/97           HYAVPYARSTPLFYYNKAAWQQAGLPD-----RGLQSWSEFDEWGPELQR
MMAR_1900|M.marinum_M               HYALPYARSTPLFYYNKAVWQRAGLPD-----RGPNSWQEFDDWGPRLQR
MSMEG_5574|M.smegmatis_MC2_155      MYSVPFYGESSFLMYRKDLFEQAGIEMP-----RTPTWQQVADAAAELNG
TH_2011|M.thermoresistible__bu      MYAVPFYGESSFLMYRKDLFEKSGIDMP-----HNPTWQQVADAAAALDT
                                     *:.*   .   : *.*  : .:*:            : :. : .  *  

MLBr_01427|M.leprae_Br4923          RDSSGRVTQWGFVNTWLSYYTAGLFALNNGVPWSNPRMNP-THLNFDDDA
MAV_2476|M.avium_104                RDASGRAAQYGFVNTWGSYYSAGLFAMNNGVPWSDPRLNP-THFNFDNAA
Rv2833c|M.tuberculosis_H37Rv        VVGAGRSAHG-----WANADLISWTFQGPNWAFGGAYSDK-WTLTLTEPA
Mb2857c|M.bovis_AF2122/97           VVGAGRSAHG-----WANADLISWTFQGPNWAFGGAYSDK-WTLTLTEPA
MMAR_1900|M.marinum_M               VVDERQWAHG-----WANAELISWTFQGVNWTFDGSYSDL-WTLRFTDPD
MSMEG_5574|M.smegmatis_MC2_155      PDMVGICLRGK--PGWGEVLAPLDTVIN---TFGGRWFDMDWNAQLTSPE
TH_2011|M.thermoresistible__bu      PDMAGICLRGK--PGWGEVLAPLDTVIN---TFGGRWYDMDWNAQLDSPE
                                            :      * .         .   .:..   :      : .  

MLBr_01427|M.leprae_Br4923          FIEAVQFYCDLTNKYQVAPDASEQQWMATADLFSLGKAAIALGGHWRYQT
MAV_2476|M.avium_104                FQEAVQFYADLANKYRVAPNASETQSMSTPNLFAVGRAAMALGGHWRYQT
Rv2833c|M.tuberculosis_H37Rv        TIAAGNFYRNSIHGKGYAAVAN-----DIANEFATGILASAVASTGSLAG
Mb2857c|M.bovis_AF2122/97           TIAAGNFYRNSIHGKGYAAVAN-----DIANEFATGILASAVASTGSLPG
MMAR_1900|M.marinum_M               TIAAGNFYRDSIHTKRYAAVAN-----NIANEFATGIMASAVASTGSLTG
MSMEG_5574|M.smegmatis_MC2_155      VRKAVQFYVDTVREYGEPGASAAG-FGECATQFAQGRAAMWYDATSAVST
TH_2011|M.thermoresistible__bu      VEEAVSFYVNLVRDHGEPGPATSG-FGECATQFAQGRAAMWYDATSAVSV
                                       * .** :  .    .  :        .  *: *  *    .      

MLBr_01427|M.leprae_Br4923          FMRAEGLDFD-VTSLPIGPSAGTVPATRSGACSDIGATGLAIAA--SSSR
MAV_2476|M.avium_104                YLRAEGLDFD-VAPLPVGPAVG----KGQPACSDIGATGLAISS--SSPR
Rv2833c|M.tuberculosis_H37Rv        ITASARFDFG-AAPLPTGPDAA-------PACP-TGGAGLAIPAKLSEER
Mb2857c|M.bovis_AF2122/97           ITASARFDFG-AAPLPTGPDAA-------PACP-TGGAGLAIPAKLSEER
MMAR_1900|M.marinum_M               ITQMAKFDFG-AAPVPTGPGGA-------PGCP-TGGAGLAIPTKLSDER
MSMEG_5574|M.smegmatis_MC2_155      VEDPASSNVVGKVGYAMAPTME------KPNSGWLYTWALGIPK--SSDK
TH_2011|M.thermoresistible__bu      LEDPAQSNVVGKVGYALAPTVV------KADAGWLYTWALGIPA--SSDN
                                           :.   .  . .*            .      .*.*.   *. .

MLBr_01427|M.leprae_Br4923          KEQAWEFVKFATGPAGQALIGESCLFVPVLQSAIYSTG----FAKAHNRV
MAV_2476|M.avium_104                KEQAWEFVKFATGPVGQALIGESCLFVPVLRSALKSDG----FARAHRRV
Rv2833c|M.tuberculosis_H37Rv        KVNALKFIAFVTNPTNTAYFSQQTGYLPVRKSAVDDASERHYLADNPRAR
Mb2857c|M.bovis_AF2122/97           KVNALKFIAFVTNPTNTAYFSQQTGYLPVRKSAVDDASERHYLADNPRAR
MMAR_1900|M.marinum_M               KRNALRFIEYITNPVNTAYFSQRTGYLAVRKSAADVPSEQKYLADHPRAR
MSMEG_5574|M.smegmatis_MC2_155      PDAAWKFISWMTDKDYIHLVGEELGWARVPPGSRLSTYEIPEYKEASAAF
TH_2011|M.thermoresistible__bu      KDSAWKFISWMTDKNYIRLVGEELGWARVPPGNRLSTYQIPEYQQASEAF
                                       * .*: : *.      ..:   :  *  .                  

MLBr_01427|M.leprae_Br4923          ANLAVLTGG------------PVHSAGLPITPAWEKINALMDRNFGPVLR
MAV_2476|M.avium_104                GNLGVLTDG------------PAFSQGLPITPAWEKVNALMDRNFGPILR
Rv2833c|M.tuberculosis_H37Rv        VALDQLPHT------------RTQDYARVFLPGGDRIISAGLESIG--LR
Mb2857c|M.bovis_AF2122/97           VALDQLPHT------------RTQDYARVFLPGGDRIISAGLESIG--LR
MMAR_1900|M.marinum_M               VAINQLPHT------------RPQDYARVFLPGADRIISAGLESIG--LR
MSMEG_5574|M.smegmatis_MC2_155      GQVTLDSIEGADPAKPTVQPVPYTGVQFLAIPEFQDLGTRVSQQISAAIA
TH_2011|M.thermoresistible__bu      GQVTLESLENADTQHPTVQPVPYTGVQFLAIPEFQDLGTRVSQQISAAIA
                                      :   .                 .      *  : : :   ..:.  : 

MLBr_01427|M.leprae_Br4923          GVRPATSLAGLARAVDEVLNSP---------
MAV_2476|M.avium_104                GSRPATSLAGLSRSVDEVLRSP---------
Rv2833c|M.tuberculosis_H37Rv        GADVTKTFTNIQKRLQVILDRQIMRKLAGHG
Mb2857c|M.bovis_AF2122/97           GADVTKTFTNIQKRLQVILDRQIMRKLAGHG
MMAR_1900|M.marinum_M               GTNVAKTFASIERQLQIILDRQIVRKLRQHG
MSMEG_5574|M.smegmatis_MC2_155      GQKSVDEALEQAQKYAEVVGRSYQEKP----
TH_2011|M.thermoresistible__bu      GQKSVKDALAQAQKYAQVVGKTYQEKP----
                                    *   .       :    ::