For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
HGKLFGRRSLLRGAGALTAAALAPGAVGCSSDDDALTFFFAANPEETNARMRIVGEFQRDHPDIKVRAVL SGPGVMQQLSTFCAGGKCPDVLMAWDLTYAELADRGVLLDLNTLLGQDKAFAAELKSDSIEPLYETFTFN GGQYAFPEQWSGNYLFYNKQLFTNAGVQPPPCTWEQPWSFTEFLDTARALTKRDSSGRVTQWGFVNTWLS YYTAGLFALNNGVPWSNPRMNPTHLNFDDDAFIEAVQFYCDLTNKYQVAPDASEQQWMATADLFSLGKAA IALGGHWRYQTFMRAEGLDFDVTSLPIGPSAGTVPATRSGACSDIGATGLAIAASSSRKEQAWEFVKFAT GPAGQALIGESCLFVPVLQSAIYSTGFAKAHNRVANLAVLTGGPVHSAGLPITPAWEKINALMDRNFGPV LRGVRPATSLAGLARAVDEVLNSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01427 | - | - | 100% (445) | putative ABC-transport lipoprotein |
| M. leprae Br4923 | MLBr_01770 | uspC | 2e-15 | 25.81% (341) | sugar transport periplasmic binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2067c | - | 0.0 | 77.13% (446) | sugar-binding lipoprotein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2041c | - | 0.0 | 77.35% (446) | sugar-binding lipoprotein |
| M. abscessus ATCC 19977 | MAB_1715c | - | 4e-08 | 23.33% (330) | sugar ABC transporter, sugar-binding protein |
| M. marinum M | MMAR_3014 | - | 0.0 | 75.73% (445) | sugar-binding lipoprotein |
| M. avium 104 | MAV_2476 | - | 0.0 | 77.10% (441) | sugar ABC transporter, sugar-binding protein |
| M. smegmatis MC2 155 | MSMEG_4468 | - | 1e-17 | 27.25% (378) | extracellular solute-binding protein UspC |
| M. thermoresistible (build 8) | TH_2011 | - | 9e-14 | 25.41% (370) | substrate binding protein |
| M. ulcerans Agy99 | MUL_1246 | uspC | 1e-13 | 26.08% (372) | periplasmic sugar-binding lipoprotein UspC |
| M. vanbaalenii PYR-1 | Mvan_2624 | - | 6e-09 | 22.56% (399) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4468|M.smegmatis_MC2_155 ------------MRR---STLLAGGLAVTMAVLLVIAMLMGRTTEPAG--
MUL_1246|M.ulcerans_Agy99 ------------MNRPRFSTLVAVAVTLIAALLGVTAVALDRIDAPPGG-
MAB_1715c|M.abscessus_ATCC_199 ------------MKA---STRAALTLALVALLLFGVAAWLGIPTTPHG--
Mb2067c|M.bovis_AF2122/97 ------------MVNKPFERRSLLRGAGALTAASLAPWAAGCAADDDD--
Rv2041c|M.tuberculosis_H37Rv ------------MVNKPFERRSLLRGAGALTAASLAPWAAGCAADDDD--
MLBr_01427|M.leprae_Br4923 ------------MHGKLFGRRSLLRGAGALTAAALAPGAVGCSSDDD---
MMAR_3014|M.marinum_M ------------MFDKPLRRRELLRGAGLLTAAALAPVAAGCASDDD---
MAV_2476|M.avium_104 ------------MLDRPFGRRSLLRGAGALSAAALAPWSAGCGSDDDG--
TH_2011|M.thermoresistible__bu --------------VRRTPIRAVLAAVAAVCLTLTGCAGAGTLGSSGN--
Mvan_2624|M.vanbaalenii_PYR-1 MRITQWPTSGRRSGRPGTAFSAVMALVAVLALVLTGCAGSGGPEQAEATG
. .
MSMEG_4468|M.smegmatis_MC2_155 --------KTVVTVRLWDPQVAAAYRESFDAFSAEHPGIEVRVNTVAYA-
MUL_1246|M.ulcerans_Agy99 --------KIVVTVRLWAAPIAAAYQQSFAAFSRTHPNIEVHTNLVSFS-
MAB_1715c|M.abscessus_ATCC_199 --------KTVVTVRVWDQQVAEAYRGSFDEFSRRNPDIQVAVTVTSYA-
Mb2067c|M.bovis_AF2122/97 ---------ALTFFFAANPDELRPRMRVVNEFQRRYPDIKVRA-LLSGP-
Rv2041c|M.tuberculosis_H37Rv ---------ALTFFFAANPDELRPRMRVVNEFQRRYPDIKVRA-LLSGP-
MLBr_01427|M.leprae_Br4923 ---------ALTFFFAANPEETNARMRIVGEFQRDHPDIKVRA-VLSGP-
MMAR_3014|M.marinum_M ---------ALTFFFAANPEEADARIRVVDAFGRSHPDIKVRT-LLSGP-
MAV_2476|M.avium_104 ---------ALTFFFAANPEERDARMRIIDEFARRHPDIKVRA-VLSGP-
TH_2011|M.thermoresistible__bu ----------TVTIALVSNSQMSDAQRLAPHFEAANPDIRLKFVTLSENQ
Mvan_2624|M.vanbaalenii_PYR-1 TGEVSTDVSGTVRILMENVPDTDIVKSMVADFNKEYPGVEINIESLTFDQ
. . * *.:.: :
MSMEG_4468|M.smegmatis_MC2_155 SYFDSLRTDVAGGSADDIFWISNGYFAGYADNGHLLDIADLLGPDA----
MUL_1246|M.ulcerans_Agy99 TYFDTLRTDVAGGSADDIFWLSNAYLAAYADSGRLMKIDTAVDP------
MAB_1715c|M.abscessus_ATCC_199 SYFNSLRTDVAGHGADDIFWLSNAYLSDYADTGNLVPVEP----------
Mb2067c|M.bovis_AF2122/97 GVMQQLATFCAGGKCPDVLMAWELTYAELADRGVLLDLNTLLARDQVFAA
Rv2041c|M.tuberculosis_H37Rv GVMQQLATFCAGGKCPDVLMAWELTYAELADRGVLLDLNTLLARDQAFAA
MLBr_01427|M.leprae_Br4923 GVMQQLSTFCAGGKCPDVLMAWDLTYAELADRGVLLDLNTLLGQDKAFAA
MMAR_3014|M.marinum_M GALQQISTFCAGGKCPDVLMAWELSYAELADRGVFLDLNTMLARDQKFAD
MAV_2476|M.avium_104 GVMQQLSTFCVGGRCPDVLMAWELSYAELADRGVLLDLGPLLARDKAFAQ
TH_2011|M.thermoresistible__bu ARAKITASTAMGGGEFDVVMISNYETPQWAADGWLVNLSDYARQTPGYD-
Mvan_2624|M.vanbaalenii_PYR-1 MRDKLVSSFQSSSPTYDLIVVDNPWMVDFANAKFLQPLDARIDSTPDYD-
. : . *:. : * : :
MSMEG_4468|M.smegmatis_MC2_155 --ATAWEPSVVEQFTRNGALWGVPQLTDAGIAVYYNADLLEKAGVSPAD-
MUL_1246|M.ulcerans_Agy99 ---GEWEPAVVDQFTRNGVLWGVPQLTDAGIAVFYNADLLAAAGVDPAE-
MAB_1715c|M.abscessus_ATCC_199 --RADWDPSVVAQFTRDGKLWGVPQLSDAGIALYYNKNLLDAAQVDPAE-
Mb2067c|M.bovis_AF2122/97 ELKSDSIGALYETFTFNGGQYAFPEQWSG-NFLFYNKQLFDDAGVPPPP-
Rv2041c|M.tuberculosis_H37Rv ELKSDSIGALYETFTFNGGQYAFPEQWSG-NFLFYNKQLFDDAGVPPPP-
MLBr_01427|M.leprae_Br4923 ELKSDSIEPLYETFTFNGGQYAFPEQWSG-NYLFYNKQLFTNAGVQPPP-
MMAR_3014|M.marinum_M ELAADSIGALYDTFAYNGGQYAFPEQWSG-NFLFYNRGLFADGGVPPPP-
MAV_2476|M.avium_104 QLQADSIPALYETFTFNGKQYALPEQWSG-NYLFYNKRLFDEAGVPSPP-
TH_2011|M.thermoresistible__bu --EDDFIPSIRESLSYEGDMYAVPFYGES-SFLMYRKDLFEKSGIDMPHN
Mvan_2624|M.vanbaalenii_PYR-1 --AADFFKPLTDITTVDGARYGVPFYNYALGYLYNADDLTAANQQVPTT-
.: : :* :..* . : * .
MSMEG_4468|M.smegmatis_MC2_155 LSTLR-WSNGPD-DTLRPLLARLTVEES-----------GRTRQWGYNAA
MUL_1246|M.ulcerans_Agy99 LDGLR-WSPGPD-DTLRALLARLTVDADGHVGGTPGFDPGRVRQWGYNAA
MAB_1715c|M.abscessus_ATCC_199 LAELR-WDPDPEVDTLRPMLHRLTAPGH----------------WGYNAA
Mb2067c|M.bovis_AF2122/97 GSWERPWSFAEFLDAAQALTKQGRSGRD--------------RQWGFVNA
Rv2041c|M.tuberculosis_H37Rv GSWERPWSFAEFLDAAQALTKQGRSGRD--------------RQWGFVNA
MLBr_01427|M.leprae_Br4923 CTWEQPWSFTEFLDTARALTKRDSSGRV--------------TQWGFVNT
MMAR_3014|M.marinum_M TSWDQPWSFAEFLDTARALTKRDGAGRV--------------TQWGFVDT
MAV_2476|M.avium_104 TAWERPWDFSEFLDTARALTKRDASGRA--------------AQYGFVNT
TH_2011|M.thermoresistible__bu PTWQQVADAAAALDTPDMAGICLRGKPG----------------WGEVLA
Mvan_2624|M.vanbaalenii_PYR-1 --LDELVSTSKALKSGDRAGIAMQPQRG----------------YKIFEE
. . .: :
MSMEG_4468|M.smegmatis_MC2_155 NDLQGIYLNFIGSAGGTFS----EGDRFTFDNPQAVEAFEYLVRLINTDR
MUL_1246|M.ulcerans_Agy99 NDPQAIYLNYIGSAGGVFM----RDNEFAFDNPPAIDAFRYLVGLINNDH
MAB_1715c|M.abscessus_ATCC_199 NDLQGIYLNYLGSAGAVFQ----ADDKFAFAKPRAEMAFTYLVDLINVDR
Mb2067c|M.bovis_AF2122/97 WVSFYAAGLFAMNNGVPWSVPRMNPTHLNFDHDGFLEAVQFYADLTNKHK
Rv2041c|M.tuberculosis_H37Rv WVSFYAAGLFAMNNGVPWSVPRMNPTHLNFDHDGFLEAVQFYADLTNKHK
MLBr_01427|M.leprae_Br4923 WLSYYTAGLFALNNGVPWSNPRMNPTHLNFDDDAFIEAVQFYCDLTNKYQ
MMAR_3014|M.marinum_M FVPPLSAGLFALNNGVPWSTPRMNPTHLNFDDDAFIEAVQFYADLSAKHQ
MAV_2476|M.avium_104 WGSYYSAGLFAMNNGVPWSDPRLNPTHFNFDNAAFQEAVQFYADLANKYR
TH_2011|M.thermoresistible__bu PLDTVINTFGGRWYDMDWN--------AQLDSPEVEEAVSFYVNLVRDHG
Mvan_2624|M.vanbaalenii_PYR-1 WGNWLFAAGGSIYD---------ADGKITLNTPEAKRALEAYIDTYNTAA
: *.
MSMEG_4468|M.smegmatis_MC2_155 VAPPASDTNDNGDFSRNAFLAGRMALFQSGTYNLAAIAD-QAPFPWGVAM
MUL_1246|M.ulcerans_Agy99 VAPPASDTNDNGDFSRNQFLAGRMALFQSGTYSLAPVAR-DATFRWGVAM
MAB_1715c|M.abscessus_ATCC_199 VAPSAADTNDNNDFSRNQFLQGRMALFQSGTYNLAQIQA-NATFPWDVAM
Mb2067c|M.bovis_AF2122/97 VAPSAAEQQSMS--TADLFSVGKAGIALAGHWRYQTFDR-ADGLDFDVAP
Rv2041c|M.tuberculosis_H37Rv VAPSAAEQQSMS--TADLFSVGKAGIALAGHWRYQTFDR-ADGLDFDVAP
MLBr_01427|M.leprae_Br4923 VAPDASEQQWMA--TADLFSLGKAAIALGGHWRYQTFMR-AEGLDFDVTS
MMAR_3014|M.marinum_M VAPTASELQSIA--TTDLFSLGKAAMALGGHWRYQTFDR-ADGLEFDVTA
MAV_2476|M.avium_104 VAPNASETQSMS--TPNLFAVGRAAMALGGHWRYQTYLR-AEGLDFDVAP
TH_2011|M.thermoresistible__bu EPGPATSGFGEC---ATQFAQGRAAMWYDATSAVSVLEDPAQSNVVGKVG
Mvan_2624|M.vanbaalenii_PYR-1 PANSLSWGMDEA---QRSVSANQAASMINYNWQLPALNEPGSGPAAGKIK
. : . .: . .
MSMEG_4468|M.smegmatis_MC2_155 LPIGPKG---------RVSVTNGIAAAGNAATRHPEAVREVLAWMGSRRG
MUL_1246|M.ulcerans_Agy99 LPIGPAG---------RVSVTNGIAAAGNSASQHPDAVRQVLAWMGSSAG
MAB_1715c|M.abscessus_ATCC_199 MPAGPQG---------RVSVTNGIVAAANSSSPHPDAVHKVLAWMGSTDG
Mb2067c|M.bovis_AF2122/97 LPIGPRG-------RAACSDIGVTGLAIAATSRRKDQAWEFVKFATGPVG
Rv2041c|M.tuberculosis_H37Rv LPIGPRG-------RAACSDIGVTGLAIAATSRRKDQAWEFVKFATGPVG
MLBr_01427|M.leprae_Br4923 LPIGPSAGTVPATRSGACSDIGATGLAIAASSSRKEQAWEFVKFATGPAG
MMAR_3014|M.marinum_M LPLGPNG-------RAACSNIGATGLAIAASSARKEQAWEFVKFATGPAG
MAV_2476|M.avium_104 LPVGPAVGK----GQPACSDIGATGLAISSSSPRKEQAWEFVKFATGPVG
TH_2011|M.thermoresistible__bu YALAPTVVK------ADAGWLYTWALGIPASSDNKDSAWKFISWMTDKNY
Mvan_2624|M.vanbaalenii_PYR-1 LATIPGG----------KQVLGSWSWAIPANSATPDAAWAFVSWITAKPN
. * . : : : . .: :
MSMEG_4468|M.smegmatis_MC2_155 NEFVGRRG-------------AAIPAVLAAQPVY---HEYWASRGVDVSP
MUL_1246|M.ulcerans_Agy99 NEYLGRDG-------------VAIPAVRSAQPSY---FAFWEAKGVNVNP
MAB_1715c|M.abscessus_ATCC_199 NSFLGRSG-------------SAIPAVLSARAPY---FQYWADKGVDVSP
Mb2067c|M.bovis_AF2122/97 QALIGESR-------------LFVPVLRSAINSH---GFANAHRRVGNLA
Rv2041c|M.tuberculosis_H37Rv QALIGESR-------------LFVPVLRSAINSH---GFANAHRRVGNLA
MLBr_01427|M.leprae_Br4923 QALIGESC-------------LFVPVLQSAIYST---GFAKAHNRVANLA
MMAR_3014|M.marinum_M QALIGETD-------------LFVPVLGSALNSA---GFAKAHRRVDNLA
MAV_2476|M.avium_104 QALIGESC-------------LFVPVLRSALKSD---GFARAHRRVGNLG
TH_2011|M.thermoresistible__bu IRLVGEELGWARVPPGNRLSTYQIPEYQQASEAFGQVTLESLENADTQHP
Mvan_2624|M.vanbaalenii_PYR-1 DVVRTEKG--------------GAAIRQSTLQDP---AVLGGQFGEEYYR
. . :
MSMEG_4468|M.smegmatis_MC2_155 FFRVLQGPRIAAPGGAGFPAGFEALTPYFAEMFLGRRDVAGTLAEAQRAA
MUL_1246|M.ulcerans_Agy99 FFAVLSGSRIPAPGGAGFAAGNDALKPYFDEMFLGRGQVATILREAQAAA
MAB_1715c|M.abscessus_ATCC_199 FFEVLRGQQIAAPGGQGFGAGFAALKPYFAEMFLGRLDVREALQQAQRAA
Mb2067c|M.bovis_AF2122/97 VLSEGPAYSEGLPVTPAWEKIAALMDRYFGPVLRGSRPATSLTGLSQAVD
Rv2041c|M.tuberculosis_H37Rv VLSEGPAYSEGLPVTPAWEKIAALMDRYFGPVLRGSRPATSLTGLSQAVD
MLBr_01427|M.leprae_Br4923 VLTGGPVHSAGLPITPAWEKINALMDRNFGPVLRGVRPATSLAGLARAVD
MMAR_3014|M.marinum_M VLTAGPGHSQGLPITPAWPKVHALMDRNFGPVLRGSRPATSLIGMSRALD
MAV_2476|M.avium_104 VLTDGPAFSQGLPITPAWEKVNALMDRNFGPILRGSRPATSLAGLSRSVD
TH_2011|M.thermoresistible__bu TVQPVPYTGVQFLAIPEFQDLGTRVSQQISAAIAGQKSVKDALAQAQKYA
Mvan_2624|M.vanbaalenii_PYR-1 TVEQLLANAAPLTQGPSGEEMIQAVGTELNEAVAGKKSVDDALAAAQAEA
. : : . * . ::
MSMEG_4468|M.smegmatis_MC2_155 NAAASR-----
MUL_1246|M.ulcerans_Agy99 NAAARR-----
MAB_1715c|M.abscessus_ATCC_199 NRALER-----
Mb2067c|M.bovis_AF2122/97 EVLRNP-----
Rv2041c|M.tuberculosis_H37Rv EVLRNP-----
MLBr_01427|M.leprae_Br4923 EVLNSP-----
MMAR_3014|M.marinum_M EVLRSP-----
MAV_2476|M.avium_104 EVLRSP-----
TH_2011|M.thermoresistible__bu QVVGKTYQEKP
Mvan_2624|M.vanbaalenii_PYR-1 EKIQG------
: