For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RITQWPTSGRRSGRPGTAFSAVMALVAVLALVLTGCAGSGGPEQAEATGTGEVSTDVSGTVRILMENVPD TDIVKSMVADFNKEYPGVEINIESLTFDQMRDKLVSSFQSSSPTYDLIVVDNPWMVDFANAKFLQPLDAR IDSTPDYDAADFFKPLTDITTVDGARYGVPFYNYALGYLYNADDLTAANQQVPTTLDELVSTSKALKSGD RAGIAMQPQRGYKIFEEWGNWLFAAGGSIYDADGKITLNTPEAKRALEAYIDTYNTAAPANSLSWGMDEA QRSVSANQAASMINYNWQLPALNEPGSGPAAGKIKLATIPGGKQVLGSWSWAIPANSATPDAAWAFVSWI TAKPNDVVRTEKGGAAIRQSTLQDPAVLGGQFGEEYYRTVEQLLANAAPLTQGPSGEEMIQAVGTELNEA VAGKKSVDDALAAAQAEAEKIQG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2624 | - | - | 100% (444) | extracellular solute-binding protein |
| M. vanbaalenii PYR-1 | Mvan_2544 | - | 1e-10 | 25.43% (350) | extracellular solute-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2345 | uspC | 9e-09 | 25.05% (459) | periplasmic sugar-binding lipoprotein UspC |
| M. gilvum PYR-GCK | Mflv_3775 | - | 0.0 | 92.79% (444) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv2318 | uspC | 2e-08 | 24.24% (458) | periplasmic sugar-binding lipoprotein UspC |
| M. leprae Br4923 | MLBr_01427 | - | 2e-09 | 22.56% (399) | putative ABC-transport lipoprotein |
| M. abscessus ATCC 19977 | MAB_1372 | - | 4e-05 | 24.15% (207) | sugar ABC transporter, sugar-binding protein LpqY |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_2088 | - | 1e-05 | 21.66% (457) | extracellular solute-binding protein |
| M. smegmatis MC2 155 | MSMEG_3111 | - | 1e-165 | 65.68% (440) | extracellular solute-binding protein, family protein 1 |
| M. thermoresistible (build 8) | TH_2011 | - | 1e-34 | 26.16% (451) | substrate binding protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2624|M.vanbaalenii_PYR-1 MRITQWPTSGRRSGRPGTAFSAVMALVAVLALVLTGCAGSGGPEQAEAT-
Mflv_3775|M.gilvum_PYR-GCK MRFAQIPT-ARRGGK--TARSAVLALLAVLALVLSACAGSGGPEQAEST-
MSMEG_3111|M.smegmatis_MC2_155 ---MKIPQLRRRRRR--PAITAITAMSVAAGLVLSGCAGTGGPANDEATS
Mb2345|M.bovis_AF2122/97 ------MTRPRQSTLVATALVLVAILLGVTAVLLGLSAEPRGGK------
Rv2318|M.tuberculosis_H37Rv ------MTRPRQSTLVATALVLVAILLGVTAVLLGLSAEPRGGK------
MAV_2088|M.avium_104 ------MTRPRFSTLVAGAVALVAALLAAAAVLLDYSGQPHGDK------
TH_2011|M.thermoresistible__bu --------------VRRTPIRAVLAAVAAVCLTLTGCAGAGTLGS-----
MLBr_01427|M.leprae_Br4923 ---------MHGKLFGRRSLLRGAGALTAAALAPGAVGCSSDDD------
MAB_1372|M.abscessus_ATCC_1997 --------MLESSARWFRRKGVALGSSLLTCLTLASLTGCARSDD-----
:
Mvan_2624|M.vanbaalenii_PYR-1 GTGEVSTDVSGTVRILMENVPDTDIVKSMVADFNKEYP---GVEINIESL
Mflv_3775|M.gilvum_PYR-GCK GSGEVSADTSGTVRILMENVPDTDIVKSMVADFNAEYP---GVEINIESL
MSMEG_3111|M.smegmatis_MC2_155 GVGDVPTDTSATVRVLMENVPDTDIVQGLVGQFNEKYP---DIKVDIETM
Mb2345|M.bovis_AF2122/97 ----------IVVTVRLWDEPIAAAYRQSFAAFTRSHP---DIEVRTNLV
Rv2318|M.tuberculosis_H37Rv ----------IVVTVRLWDEPIAAAYRQSFAAFTRSHP---DIEVRTNLV
MAV_2088|M.avium_104 ----------TIVTVRVWGDELAEAYRQSFAAFTRAHP---DIEVHVNMV
TH_2011|M.thermoresistible__bu --------SGNTVTIALVSNSQMSDAQRLAPHFEAANP---DIRLKFVTL
MLBr_01427|M.leprae_Br4923 ----------ALTFFFAANPEETNARMRIVGEFQRDHP---DIKVRAVLS
MAB_1372|M.abscessus_ATCC_1997 ----------QIVIRFYTPASEAGTFSAAAQRCNRELGGRFTILQVSLPK
. :
Mvan_2624|M.vanbaalenii_PYR-1 TFDQMRDKLVSSFQSSSPTYDLIVVDNPWMVDFANAKFLQPLDARIDST-
Mflv_3775|M.gilvum_PYR-GCK TFDQMRDKLVSSFQSSSPAYDLIVVDNPWMVDFANAKFLQPLDARIDST-
MSMEG_3111|M.smegmatis_MC2_155 TFDQMRDRLVSSFQAAQPAYDLIVVDNPWMDDFADAGFLQPLDERIAAT-
Mb2345|M.bovis_AF2122/97 AYSTYFETLRTDVAGGS-ADDIFWLSNAYFAAYADSGRLMKIQT------
Rv2318|M.tuberculosis_H37Rv AYSTYFETLRTDVAGGS-ADDIFWLSNAYFAAYADSGRLMKIQT------
MAV_2088|M.avium_104 AYSTYFNTLRTDVAGGS-ADDIFWLSNAYLAAYADSGRLLNILDTLGTN-
TH_2011|M.thermoresistible__bu SENQARAKITASTAMGGGEFDVVMISNYETPQWAADGWLVNLSDYARQT-
MLBr_01427|M.leprae_Br4923 --GPGVMQQLSTFCAGGKCPDVLMAWDLTYAELADRGVLLDLNTLLGQDK
MAB_1372|M.abscessus_ATCC_1997 RADEQRLQLARRLTGNDRTLDLMGMDVVWTAEFAEAGWALPLSDDPAGVT
. *:. * :
Mvan_2624|M.vanbaalenii_PYR-1 --PDYDAADFFKPLTDITTVDGARYGVPFYNYALGYLYNADDLTAANQQV
Mflv_3775|M.gilvum_PYR-GCK --PDYDAGDFFTPLTDITTVDGTRYGVPFYNYALGYLYNADDLAAANQQV
MSMEG_3111|M.smegmatis_MC2_155 --TDFRPDDFFPSLTDITDVDGTTYGVPFYNYALGYIYNKDDLAAAGASV
Mb2345|M.bovis_AF2122/97 -----DAADWEPAVVDQFTRSGVLWGVPQLTDAGIAVFYNADLLAAAGVD
Rv2318|M.tuberculosis_H37Rv -----DAADWEPAVVDQFTRSGVLWGVPQLTDAGIAVFYNADLLAAAGVD
MAV_2088|M.avium_104 -----AAADWERPVVEQFTRHGQLWGVPQLTDAGIALYYNADLLGAAGID
TH_2011|M.thermoresistible__bu --PGYDEDDFIPSIRESLSYEGDMYAVPFYGESSFLMYRKDLFEKSGIDM
MLBr_01427|M.leprae_Br4923 AFAAELKSDSIEPLYETFTFNGGQYAFPEQWSGNYLFYNKQLFTNAGVQP
MAB_1372|M.abscessus_ATCC_1997 --EAAAQRDALAGPLESARWKGKLYAAPLSTNTQLLWYRKDLVP----EP
* : * :. * : .
Mvan_2624|M.vanbaalenii_PYR-1 PTTLDELVSTS----------KALKSGDRAGIAMQPQRGY-KIFEEWGN-
Mflv_3775|M.gilvum_PYR-GCK PTTLDELVSTS----------KALKSGDRAGIAMQPQRGY-KIFEEWGN-
MSMEG_3111|M.smegmatis_MC2_155 PTDLDALVRTS----------QQLKTADRAGIAMQPQRGY-KIFEEWAN-
Mb2345|M.bovis_AF2122/97 PTQVDNLRWSRGDDDTLRPMLARLTVDADGRTANTPGFDA-RRVRQWGYN
Rv2318|M.tuberculosis_H37Rv PTQVDNLRWSRGDDDTLRPMLARLTVDADGRTANTPGFDA-RRVRQWGYN
MAV_2088|M.avium_104 PAQLNSLRWNPAGGDTLRPLLARLTVDADGNRGDTRGFDP-GRVRQWGYN
TH_2011|M.thermoresistible__bu PHNPTWQQVAD--------AAAALDTPDMAGICLRGKPGWGEVLAPLDT-
MLBr_01427|M.leprae_Br4923 PPCTWEQPWSFT-----EFLDTARALTKRDSSGRVTQWGFVNTWLSYYTA
MAB_1372|M.abscessus_ATCC_1997 PATWDQTVREA----------ENFARSEGPSWIALQGKQYEGLVVLFNT-
*
Mvan_2624|M.vanbaalenii_PYR-1 ----------WLFAAGGSIYDAD------GKITLNTPEAKRALEAYIDTY
Mflv_3775|M.gilvum_PYR-GCK ----------WLFAAGGSIYDAD------GKITLNTPEAKRALEAYIDTY
MSMEG_3111|M.smegmatis_MC2_155 ----------WLFAAGGSIYDKD------GNPTLDTEQAARALDAYIETY
Mb2345|M.bovis_AF2122/97 AANDPQAIYLNYIGSAGGVFQRD------GKFAFDNPGAIEAFRYLVGLI
Rv2318|M.tuberculosis_H37Rv AANDPQAIYLNYIGSAGGVFQRD------GKFAFDNPGAIEAFRYLVGLI
MAV_2088|M.avium_104 AANDPQGIYLNYIGSAGGVFQRG------DEFAFDNPAAVSAFRYLVDLI
TH_2011|M.thermoresistible__bu ----------VINTFGGRWYDMD------WNAQLDSPEVEEAVSFYVNLV
MLBr_01427|M.leprae_Br4923 G---------LFALNNGVPWSNPR--MNPTHLNFDDDAFIEAVQFYCDLT
MAB_1372|M.abscessus_ATCC_1997 ----------LLSSAGGSVLAGDGKTVTLTDTPAHRQATVTALRTMKSIA
* . . *.
Mvan_2624|M.vanbaalenii_PYR-1 NTAAPANSLSWG-MDEAQRSVSANQAASMINYNWQLPALN----------
Mflv_3775|M.gilvum_PYR-GCK NTAAPANSLSWG-MDEAQRSVSANQSASMINYNWQLPALN----------
MSMEG_3111|M.smegmatis_MC2_155 RTAAPANSLAWG-FDEAFRSVSSGKAASMVGYNWNLPALN----------
Mb2345|M.bovis_AF2122/97 NDDHVAPPASDT-NDNGDFSRNQFLAGKMALFQSGTYSLA----------
Rv2318|M.tuberculosis_H37Rv NDDHVAPPASDT-NDNGDFSRNQFLAGKMALFQSGTYSLA----------
MAV_2088|M.avium_104 NRDHVAPPAADT-NDNGDFSRNQFLAGRMALFQSGTYNLA----------
TH_2011|M.thermoresistible__bu RDHGEPGPATSG-FGECATQFAQGRAAMWYDATSAVSVLE----------
MLBr_01427|M.leprae_Br4923 NKYQVAPDASEQQWMATADLFSLGKAAIALGGHWRYQTFMR---------
MAB_1372|M.abscessus_ATCC_1997 TADGADPSITQTDEGTARLAFEQGKAAFEINWPFVMASMMENAIKGGVPF
: :. :
Mvan_2624|M.vanbaalenii_PYR-1 --------------------------EPG---SGPAAGKIKLATIPGGK-
Mflv_3775|M.gilvum_PYR-GCK --------------------------EPG---SGPAAGKIKLATIPGGK-
MSMEG_3111|M.smegmatis_MC2_155 --------------------------DPAGA-SGERAGQFALAPIPGGK-
Mb2345|M.bovis_AF2122/97 --------------------------PVARD-ALFHWGVAMLPAGPAGR-
Rv2318|M.tuberculosis_H37Rv --------------------------PVARD-ALFHWGVAMLPAGPAGR-
MAV_2088|M.avium_104 --------------------------PVARD-ARFRWGVAMMPAGPVGR-
TH_2011|M.thermoresistible__bu --------------------------DPAQSNVVGKVGYALAPTVVKAD-
MLBr_01427|M.leprae_Br4923 ----------------------AEGLDFDVTSLPIGPSAGTVPATRSGA-
MAB_1372|M.abscessus_ATCC_1997 LRLDRRPDLTGAIGDAGRFAPSEEQFAAAYEAASAALGFAPFPSVVAGQP
. .. .
Mvan_2624|M.vanbaalenii_PYR-1 -QVLG-SWSWAIPANSATPDAAWAFVSWITAKPNDVVRTEKG--GAAIRQ
Mflv_3775|M.gilvum_PYR-GCK -QVLG-SWSWAIPANSATPDAAWAFVSWITAKPNDVVRTEKG--GAAIRK
MSMEG_3111|M.smegmatis_MC2_155 -SALG-LWSWAIPANSAASDAAWAFISWITSPEIDAERVAKG--GAVVRE
Mb2345|M.bovis_AF2122/97 -VSVTNGIAAAGNSASKHPDAVRQVLAWMGSTEGNSYVGRHG--AAIP--
Rv2318|M.tuberculosis_H37Rv -VSVTNGIAAAGNSASKHPDAVRQVLAWMGSTEGNSYLGRHG--AAIP--
MAV_2088|M.avium_104 -VSVTNGIAAAGNAATKHPGAVRQVLAWMGSRQGNEYLGRYG--AAIP--
TH_2011|M.thermoresistible__bu -AGWLYTWALGIPASSDNKDSAWKFISWMTDKNYIRLVGEELGWARVPPG
MLBr_01427|M.leprae_Br4923 -CSDIGATGLAIAASSSRKEQAWEFVKFATGPAGQALIGESC------LF
MAB_1372|M.abscessus_ATCC_1997 ARVTIGGLNIAVAKTTRYKAQAFEALNCLRSRENQKATAIEG-------G
. : . :
Mvan_2624|M.vanbaalenii_PYR-1 STLQDPAVLGGQFGEEYYRTVEQLLANAAPLTQGPSGE------------
Mflv_3775|M.gilvum_PYR-GCK STLQNPAVLQGQFGEEYYRTVEQLLADAAPLTQGPSGE------------
MSMEG_3111|M.smegmatis_MC2_155 SSLTNEKVLKDGYGEDYYRVVGEILSDAAPLTQGKGGE------------
Mb2345|M.bovis_AF2122/97 AVLSAQPVYFDYWSARGVDVTPFFAVLNGPRIAAPGGAG-----------
Rv2318|M.tuberculosis_H37Rv AVLSAQPVYFDYWSARGVDVTPFFAVLNGPRIAAPGGAG-----------
MAV_2088|M.avium_104 AVTSAQPVYFGYWAARGVDVTPFFAVLNGPRIAAPGGAG-----------
TH_2011|M.thermoresistible__bu NRLSTYQIPEYQQASEAFGQVTLESLENADTQHPTVQPVPYTGVQFLAIP
MLBr_01427|M.leprae_Br4923 VPVLQSAIYSTGFAKAHNRVANLAVLTGGPVHSAGLPITP----------
MAB_1372|M.abscessus_ATCC_1997 LPAVDSSLYDDPEFQAKYPAYAIIRDQLANAAVRPASPY-----------
: .
Mvan_2624|M.vanbaalenii_PYR-1 ---EMIQAVGTELNEAVAGKKSVDDALAAAQAEAEKIQG------
Mflv_3775|M.gilvum_PYR-GCK ---EMIQAVGTALNEAVAGEKSVDDALATAQAEAEKIQG------
MSMEG_3111|M.smegmatis_MC2_155 ---EMIQAVGTELNDAAAGNKSVADALRDAQAAVERIQK------
Mb2345|M.bovis_AF2122/97 -FAAGQQALEPYFDEMFLGRGDVTTTLRQAQAAANAATQR-----
Rv2318|M.tuberculosis_H37Rv -FAAGQQALEPYFDEMFLGRGDVTTTLRQAQAAANAATQR-----
MAV_2088|M.avium_104 -FAAGNDALRPYFDEMFSGRGDVATTLRRAQAAANAAAARR----
TH_2011|M.thermoresistible__bu EFQDLGTRVSQQISAAIAGQKSVKDALAQAQKYAQVVGKTYQEKP
MLBr_01427|M.leprae_Br4923 AWEKINALMDRNFGPVLRGVRPATSLAGLARAVDEVLNSP-----
MAB_1372|M.abscessus_ATCC_1997 -YQAISTRVSAVLAPITGIDPERTADLLNDQVQKAVDGRGLIP--
: : :