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M. thermoresistible (build 8) TH_2011 (-)

annotation: substrate binding protein
coordinates: 3917881 - 3919227
length: 449

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2011--100% (449)substrate binding protein
M. thermoresistible (build 8)TH_2061lpqY2e-0522.03% (395) PROBABLE SUGAR-BINDING LIPOPROTEIN LPQY

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2857cugpB9e-1524.52% (363) sn-glycerol-3-phosphate-binding lipoprotein UGPB
M. gilvum PYR-GCKMflv_3775-2e-3425.56% (450) extracellular solute-binding protein
M. tuberculosis H37RvRv2833cugpB2e-1524.52% (363) sn-glycerol-3-phosphate-binding lipoprotein UGPB
M. leprae Br4923MLBr_01427-4e-1425.41% (370) putative ABC-transport lipoprotein
M. abscessus ATCC 19977MAB_1715c-5e-0922.92% (336) sugar ABC transporter, sugar-binding protein
M. marinum MMMAR_3014-3e-1526.56% (369) sugar-binding lipoprotein
M. avium 104MAV_2476-8e-1525.00% (364) sugar ABC transporter, sugar-binding protein
M. smegmatis MC2 155MSMEG_5574-0.080.41% (444) substrate binding protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_2624-2e-3426.16% (451) extracellular solute-binding protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_2011|M.thermoresistible__bu      --------------VRRTPIRAVLAAVAAVCLTLTG-CAGAG--------
MSMEG_5574|M.smegmatis_MC2_155      --------------MKR--LRRLAACIAAAGLTATAGCAGAG--------
Mflv_3775|M.gilvum_PYR-GCK          MRFAQIPT-ARRGGK--TARSAVLALLAVLALVLSA-CAGSGGPEQAEST
Mvan_2624|M.vanbaalenii_PYR-1       MRITQWPTSGRRSGRPGTAFSAVMALVAVLALVLTG-CAGSGGPEQAEAT
Mb2857c|M.bovis_AF2122/97           ---------------MDPLNRRQFLALAAAAAGVTAGCAGMGG-------
Rv2833c|M.tuberculosis_H37Rv        ---------------MDPLNRRQFLALAAAAAGVTAGCAGMGG-------
MLBr_01427|M.leprae_Br4923          -------------MHGKLFGRR---SLLRGAGALTAAALAPGA-------
MMAR_3014|M.marinum_M               -------------MFDKPLRRR---ELLRGAGLLTAAALAPVA-------
MAV_2476|M.avium_104                -------------MLDRPFGRR---SLLRGAGALSAAALAPWS-------
MAB_1715c|M.abscessus_ATCC_199      ----------------MKASTRAALTLALVALLLFGVAAWLGIP------
                                                              :        . .            

TH_2011|M.thermoresistible__bu      ----TLGSSGNTVTIALVSNSQMSDAQRLAPHFEAANPDIRLKFVTLSEN
MSMEG_5574|M.smegmatis_MC2_155      ----TLGATDQTVTIAMVSNSQMTDARELSSRFEAENPDIKLRFVTLSEN
Mflv_3775|M.gilvum_PYR-GCK          GSGEVSADTSGTVRILMENVPDTDIVKSMVADFNAEYPGVEINIESLTFD
Mvan_2624|M.vanbaalenii_PYR-1       GTGEVSTDVSGTVRILMENVPDTDIVKSMVADFNKEYPGVEINIESLTFD
Mb2857c|M.bovis_AF2122/97           -GGSVKSGSGPIDFWSSHPGQSSAAERELIGRFQDRFPTLSVKLIDAGKD
Rv2833c|M.tuberculosis_H37Rv        -GGSVKSGSGPIDFWSSHPGQSSAAERELIGRFQDRFPTLSVKLIDAGKD
MLBr_01427|M.leprae_Br4923          -VGCSSDDD-ALTFFFAANPEETNARMRIVGEFQRDHPDIKVRAVLSGPG
MMAR_3014|M.marinum_M               -AGCASDDD-ALTFFFAANPEEADARIRVVDAFGRSHPDIKVRTLLSGPG
MAV_2476|M.avium_104                -AGCGSDDDGALTFFFAANPEERDARMRIIDEFARRHPDIKVRAVLSGPG
MAB_1715c|M.abscessus_ATCC_199      ----TTPHGKTVVTVRVWDQQVAEAYRGSFDEFSRRNPDIQVAVTVTSYA
                                                                    *    * : :        

TH_2011|M.thermoresistible__bu      -QARAKITASTAMGGGEFDVVMISNYETPQWAADGWLVNLSDYARQTP--
MSMEG_5574|M.smegmatis_MC2_155      -QARAKITASTAMGGGEFDVVMISNYETPQWAENGWLVDLSDYARNTP--
Mflv_3775|M.gilvum_PYR-GCK          -QMRDKLVSSFQSSSPAYDLIVVDNPWMVDFANAKFLQPLDARIDSTP--
Mvan_2624|M.vanbaalenii_PYR-1       -QMRDKLVSSFQSSSPTYDLIVVDNPWMVDFANAKFLQPLDARIDSTP--
Mb2857c|M.bovis_AF2122/97           YDEVAQKFNAALIGTDVPDVVLLDDRWWFHFALIGVLTALDDLFGQVG--
Rv2833c|M.tuberculosis_H37Rv        YDEVAQKFNAALIGTDVPDVVLLDDRWWFHFALSGVLTALDDLFGQVG--
MLBr_01427|M.leprae_Br4923          ---VMQQLSTFCAGGKCPDVLMAWDLTYAELADRGVLLDLNTLLGQDKAF
MMAR_3014|M.marinum_M               ---ALQQISTFCAGGKCPDVLMAWELSYAELADRGVFLDLNTMLARDQKF
MAV_2476|M.avium_104                ---VMQQLSTFCVGGRCPDVLMAWELSYAELADRGVLLDLGPLLARDKAF
MAB_1715c|M.abscessus_ATCC_199      --SYFNSLRTDVAGHGADDIFWLSNAYLSDYADTGNLVPVEPRADWDP--
                                         :   :   .    *:.   :    . *    :  :          

TH_2011|M.thermoresistible__bu      -GYDEDDFIPSIRESLSYEGDMYAVPFYGES-SFLMYRKDLFEKSGIDMP
MSMEG_5574|M.smegmatis_MC2_155      -GYDEDDFIPSLKDSLSYQGDMYSVPFYGES-SFLMYRKDLFEQAGIEMP
Mflv_3775|M.gilvum_PYR-GCK          -DYDAGDFFTPLTDITTVDGTRYGVPFYNYA-LGYLYNADDLAAANQQVP
Mvan_2624|M.vanbaalenii_PYR-1       -DYDAADFFKPLTDITTVDGARYGVPFYNYA-LGYLYNADDLTAANQQVP
Mb2857c|M.bovis_AF2122/97           --VDTTDYVDSLLADYEFNGRHYAVPYARST-PLFYYNKAAWQQAGLPD-
Rv2833c|M.tuberculosis_H37Rv        --VDTTDYVDSLLADYEFNGRHYAVPYARST-PLFYYNKAAWQQAGLPD-
MLBr_01427|M.leprae_Br4923          AAELKSDSIEPLYETFTFNGGQYAFPEQWSG-NYLFYNKQLFTNAGVQPP
MMAR_3014|M.marinum_M               ADELAADSIGALYDTFAYNGGQYAFPEQWSG-NFLFYNRGLFADGGVPPP
MAV_2476|M.avium_104                AQQLQADSIPALYETFTFNGKQYALPEQWSG-NYLFYNKRLFDEAGVPSP
MAB_1715c|M.abscessus_ATCC_199      ----------SVVAQFTRDGKLWGVPQLSDAGIALYYNKNLLDAAQVDPA
                                              .:      :*  :..*          *.      .     

TH_2011|M.thermoresistible__bu      H-----NPTWQQVADAAAALDTPDMAGICLRGKPGWGEVLAPLDTVINTF
MSMEG_5574|M.smegmatis_MC2_155      R-----TPTWQQVADAAAELNGPDMVGICLRGKPGWGEVLAPLDTVINTF
Mflv_3775|M.gilvum_PYR-GCK          -------TTLDELVSTSKALKSGDRAGIAMQPQRGY-KIFEEWGNWLFAA
Mvan_2624|M.vanbaalenii_PYR-1       -------TTLDELVSTSKALKSGDRAGIAMQPQRGY-KIFEEWGNWLFAA
Mb2857c|M.bovis_AF2122/97           ----RGLQSWSEFDEWGPELQRVVGAGRSAHG-----WANADLISWTFQG
Rv2833c|M.tuberculosis_H37Rv        ----RGPQSWSEFDEWGPELQRVVGAGRSAHG-----WANADLISWTFQG
MLBr_01427|M.leprae_Br4923          PCTWEQPWSFTEFLDTARALTKRDSSGRVTQWGFVNTWLSYYTAGLFALN
MMAR_3014|M.marinum_M               PTSWDQPWSFAEFLDTARALTKRDGAGRVTQWGFVDTFVPPLSAGLFALN
MAV_2476|M.avium_104                PTAWERPWDFSEFLDTARALTKRDASGRAAQYGFVNTWGSYYSAGLFAMN
MAB_1715c|M.abscessus_ATCC_199      ELAELRWDPDPEVDTLRPMLHRLTAPG-----HWGYNAANDLQGIYLNYL
                                               :.      *      *                       

TH_2011|M.thermoresistible__bu      G----GRWYDMDWNAQLDSPEVEEAVSFYVNLVRDHGEPGPATSG---FG
MSMEG_5574|M.smegmatis_MC2_155      G----GRWFDMDWNAQLTSPEVRKAVQFYVDTVREYGEPGASAAG---FG
Mflv_3775|M.gilvum_PYR-GCK          G----GSIYDADGKITLNTPEAKRALEAYIDTYNTAAPANSLSWG---MD
Mvan_2624|M.vanbaalenii_PYR-1       G----GSIYDADGKITLNTPEAKRALEAYIDTYNTAAPANSLSWG---MD
Mb2857c|M.bovis_AF2122/97           PNWAFGGAYSDKWTLTLTEPATIAAGNFYRNSIHGKGYAAVAN-------
Rv2833c|M.tuberculosis_H37Rv        PNWAFGGAYSDKWTLTLTEPATIAAGNFYRNSIHGKGYAAVAN-------
MLBr_01427|M.leprae_Br4923          NGVPWSNPRMNPTHLNFDDDAFIEAVQFYCDLTNKYQVAPDASEQQ--WM
MMAR_3014|M.marinum_M               NGVPWSTPRMNPTHLNFDDDAFIEAVQFYADLSAKHQVAPTASELQ--SI
MAV_2476|M.avium_104                NGVPWSDPRLNPTHFNFDNAAFQEAVQFYADLANKYRVAPNASETQ--SM
MAB_1715c|M.abscessus_ATCC_199      G--SAGAVFQADDKFAFAKPRAEMAFTYLVDLINVDRVAPSAADTNDNND
                                         .          :       *     :       .           

TH_2011|M.thermoresistible__bu      ECATQFAQGRAAMWYDATSAVSVLEDPAQSNVVGKVGYALAPTVVKA---
MSMEG_5574|M.smegmatis_MC2_155      ECATQFAQGRAAMWYDATSAVSTVEDPASSNVVGKVGYAMAPTMEKP---
Mflv_3775|M.gilvum_PYR-GCK          EAQRSVSANQSASMINYNWQLPALNEPGSGPAAGKIKLATIPGGKQ----
Mvan_2624|M.vanbaalenii_PYR-1       EAQRSVSANQAASMINYNWQLPALNEPGSGPAAGKIKLATIPGGKQ----
Mb2857c|M.bovis_AF2122/97           DIANEFATGILASAVASTGSLPGITASAR-FDFGAAPLPTGPDAAP----
Rv2833c|M.tuberculosis_H37Rv        DIANEFATGILASAVASTGSLAGITASAR-FDFGAAPLPTGPDAAP----
MLBr_01427|M.leprae_Br4923          ATADLFSLGKAAIALGGHWRYQTFMRAEG-LDFDVTSLPIGPSAGTVPAT
MMAR_3014|M.marinum_M               ATTDLFSLGKAAMALGGHWRYQTFDRADG-LEFDVTALPLGPNG------
MAV_2476|M.avium_104                STPNLFAVGRAAMALGGHWRYQTYLRAEG-LDFDVAPLPVGPAVGK----
MAB_1715c|M.abscessus_ATCC_199      FSRNQFLQGRMALFQSGTYNLAQIQANAT-FPWDVAMMPAGPQGRVS---
                                         .  .  *                     .    .  *        

TH_2011|M.thermoresistible__bu      ---DAGWLYTWALGIPA--SSDNKDSAWKFISWMTDKNYIRLVGEELGWA
MSMEG_5574|M.smegmatis_MC2_155      ---NSGWLYTWALGIPK--SSDKPDAAWKFISWMTDKDYIHLVGEELGWA
Mflv_3775|M.gilvum_PYR-GCK          ------VLGSWSWAIPA--NSATPDAAWAFVSWITAK-----PNDVVRTE
Mvan_2624|M.vanbaalenii_PYR-1       ------VLGSWSWAIPA--NSATPDAAWAFVSWITAK-----PNDVVRTE
Mb2857c|M.bovis_AF2122/97           ---ACP-TGGAGLAIPAKLSEERKVNALKFIAFVTNPTNTAYFSQQTGYL
Rv2833c|M.tuberculosis_H37Rv        ---ACP-TGGAGLAIPAKLSEERKVNALKFIAFVTNPTNTAYFSQQTGYL
MLBr_01427|M.leprae_Br4923          RSGACSDIGATGLAIAA--SSSRKEQAWEFVKFATGPAGQALIGESCLFV
MMAR_3014|M.marinum_M               -RAACSNIGATGLAIAA--SSARKEQAWEFVKFATGPAGQALIGETDLFV
MAV_2476|M.avium_104                GQPACSDIGATGLAISS--SSPRKEQAWEFVKFATGPVGQALIGESCLFV
MAB_1715c|M.abscessus_ATCC_199      --------VTNGIVAAANSSSPHPDAVHKVLAWMGSTDGNSFLGRSGSAI
                                               .   .   ..     .  .: :          .      

TH_2011|M.thermoresistible__bu      RVPPGNRLSTYQIPEYQQASEAFGQVTLESLENADTQHPTVQPVPYTGVQ
MSMEG_5574|M.smegmatis_MC2_155      RVPPGSRLSTYEIPEYKEASAAFGQVTLDSIEGADPAKPTVQPVPYTGVQ
Mflv_3775|M.gilvum_PYR-GCK          KGGAAIRKSTLQNPAVLQG--QFGEEYYRTVEQLLADAAPLTQGPSG---
Mvan_2624|M.vanbaalenii_PYR-1       KGGAAIRQSTLQDPAVLGG--QFGEEYYRTVEQLLANAAPLTQGPSG---
Mb2857c|M.bovis_AF2122/97           PVRKSAVDDASERHYLADNPRARVALDQLPHTRTQDYARVFLP-------
Rv2833c|M.tuberculosis_H37Rv        PVRKSAVDDASERHYLADNPRARVALDQLPHTRTQDYARVFLP-------
MLBr_01427|M.leprae_Br4923          PVLQSAIYST----GFAKAHNRVANLAVLTGGPVHSAGLPITP-------
MMAR_3014|M.marinum_M               PVLGSALNSA----GFAKAHRRVDNLAVLTAGPGHSQGLPITP-------
MAV_2476|M.avium_104                PVLRSALKSD----GFARAHRRVGNLGVLTDGPAFSQGLPITP-------
MAB_1715c|M.abscessus_ATCC_199      PAVLSARAPYFQYWADKGVDVSPFFEVLRGQQIAAPGGQGFGAG------
                                        .                                   .         

TH_2011|M.thermoresistible__bu      FLAIPEFQDLGTRVSQQISAAIAGQKSVKDALAQAQKYAQVVGKTYQEKP
MSMEG_5574|M.smegmatis_MC2_155      FLAIPEFQDLGTRVSQQISAAIAGQKSVDEALEQAQKYAEVVGRSYQEKP
Mflv_3775|M.gilvum_PYR-GCK          -------EEMIQAVGTALNEAVAGEKSVDDALATAQAEAEKIQG------
Mvan_2624|M.vanbaalenii_PYR-1       -------EEMIQAVGTELNEAVAGKKSVDDALAAAQAEAEKIQG------
Mb2857c|M.bovis_AF2122/97           -----GGDRIISAGLESIG--LRGADVTKTFTNIQKRLQVILDRQIMRKL
Rv2833c|M.tuberculosis_H37Rv        -----GGDRIISAGLESIG--LRGADVTKTFTNIQKRLQVILDRQIMRKL
MLBr_01427|M.leprae_Br4923          -----AWEKINALMDRNFGPVLRGVRPATSLAGLARAVDEVLNSP-----
MMAR_3014|M.marinum_M               -----AWPKVHALMDRNFGPVLRGSRPATSLIGMSRALDEVLRSP-----
MAV_2476|M.avium_104                -----AWEKVNALMDRNFGPILRGSRPATSLAGLSRSVDEVLRSP-----
MAB_1715c|M.abscessus_ATCC_199      ----------FAALKPYFAEMFLGRLDVREALQQAQRAANRALER-----
                                                     :   . *   .       :              

TH_2011|M.thermoresistible__bu      ----
MSMEG_5574|M.smegmatis_MC2_155      ----
Mflv_3775|M.gilvum_PYR-GCK          ----
Mvan_2624|M.vanbaalenii_PYR-1       ----
Mb2857c|M.bovis_AF2122/97           AGHG
Rv2833c|M.tuberculosis_H37Rv        AGHG
MLBr_01427|M.leprae_Br4923          ----
MMAR_3014|M.marinum_M               ----
MAV_2476|M.avium_104                ----
MAB_1715c|M.abscessus_ATCC_199      ----