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M. smegmatis MC2 155 MSMEG_0553 (-)

annotation: sugar ABC transporter, substrate-binding protein, putative
coordinates: 629922 - 631274
length: 450

VTSPAFTRRRALQLLGLAGGAAMLAPALAACGSSGGNSALAADAPVSGRFEGVTLKLLVNQPHVTSFRDV
LAPAWQEATGGTLDVTAAPYDQLTSKQILDVQSGTGEFDVFDYFYFGLGDLVDADALVELTDWIDNRQGE
LDVSGYLKSIYDPYTLLDGKRYGLPYDGDIHILFYNAELFDRYKVEPPTTWDEYDEVAAKITKDARGTAY
GAIVSGQQVPMILGCSYINRLTGYGGNLFDENGKPALTSDASIAALEHLVAVTPAALPTPLQIGFDQANT
AFLSGQGAMLDTWTDMALRAEDPTASKIAGRWGAVSLPVGGANTTPRTALDAGFGLGISTASENTDAAAA
FIAWATAAPQNLAVSSTAGAGIDPVRGEVLDSDGYAKVVTNAVAPIRQGLGGDPLVWPKQAGAPKLLQDL
VDQLALAIAGTQTVEQSLEQAQASWDSASS

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. smegmatis MC2 155 MSMEG_0553 - - 100% (450) sugar ABC transporter, substrate-binding protein, putative
M. smegmatis MC2 155 MSMEG_5574 - 2e-20 26.20% (439) substrate binding protein
M. smegmatis MC2 155 MSMEG_3111 - 8e-17 22.74% (453) extracellular solute-binding protein, family protein 1

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 - - - - -
M. gilvum PYR-GCK Mflv_3775 - 2e-23 24.88% (434) extracellular solute-binding protein
M. tuberculosis H37Rv - - - - -
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 - - - - -
M. marinum M MMAR_3619 uspC 5e-09 24.21% (380) periplasmic sugar-binding lipoprotein UspC
M. avium 104 MAV_2476 - 1e-07 25.65% (308) sugar ABC transporter, sugar-binding protein
M. thermoresistible (build 8) TH_2011 - 6e-16 26.22% (450) substrate binding protein
M. ulcerans Agy99 MUL_1246 uspC 4e-09 24.21% (380) periplasmic sugar-binding lipoprotein UspC
M. vanbaalenii PYR-1 Mvan_2624 - 8e-25 26.21% (435) extracellular solute-binding protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3775|M.gilvum_PYR-GCK          MRFAQIPT-ARRGGK--TARSAVLALLAVLALVLSACAGSGGPEQAESTG
Mvan_2624|M.vanbaalenii_PYR-1       MRITQWPTSGRRSGRPGTAFSAVMALVAVLALVLTGCAGSGGPEQAEATG
MMAR_3619|M.marinum_M               -----------------MSRPRFSTLVAVAVTLIAALLG----VTAVALD
MUL_1246|M.ulcerans_Agy99           -----------------MNRPRFSTLVAVAVTLIAALLG----VTAVALD
TH_2011|M.thermoresistible__bu      --------------VRRTPIRAVLAAVAAVCLTLTGCAG------AGTLG
MSMEG_0553|M.smegmatis_MC2_155      ------MTSPAFTRRRALQLLGLAGGAAMLAPALAACGSSGG--NSALAA
MAV_2476|M.avium_104                -------MLDRPFGRRSLLRGAGALSAAALAPWSAGCGS-----------
                                                               *      :.  .           

Mflv_3775|M.gilvum_PYR-GCK          SGEVSADTSGTVRILMENVPDTDIVKSMVADFNAEYPGVEINIESLTFDQ
Mvan_2624|M.vanbaalenii_PYR-1       TGEVSTDVSGTVRILMENVPDTDIVKSMVADFNKEYPGVEINIESLTFDQ
MMAR_3619|M.marinum_M               RIDAPPGGKIVVTVRLWAAPIAAAYQQSFAAFSRTHPNIEVHTNLVSFST
MUL_1246|M.ulcerans_Agy99           RIDAPPGGKIVVTVRLWAAPIAAAYQQSFAAFSRTHPNIEVHTNLVSFST
TH_2011|M.thermoresistible__bu      S------SGNTVTIALVSNSQMSDAQRLAPHFEAANPDIRLKFVTLSENQ
MSMEG_0553|M.smegmatis_MC2_155      DAPVSGRFEGVTLKLLVNQPHVTSFRDVLAPAWQEATGGTLDVTAAPYDQ
MAV_2476|M.avium_104                -----DDDGALTFFFAANPEERDARMRIIDEFARRHPDIKVRAVLS--GP
                                               .                        ..  :       . 

Mflv_3775|M.gilvum_PYR-GCK          MRDKLVSSFQSSSPAYDLIVVDNPWMVDFANAKFLQPLDARIDSTPD---
Mvan_2624|M.vanbaalenii_PYR-1       MRDKLVSSFQSSSPTYDLIVVDNPWMVDFANAKFLQPLDARIDSTPD---
MMAR_3619|M.marinum_M               YFDTLRTDVAGGS-ADDIFWLSNAYLAAYADSGRLMKIDTAVD-------
MUL_1246|M.ulcerans_Agy99           YFDTLRTDVAGGS-ADDIFWLSNAYLAAYADSGRLMKIDTAVD-------
TH_2011|M.thermoresistible__bu      ARAKITASTAMGGGEFDVVMISNYETPQWAADGWLVNLSDYARQTPG---
MSMEG_0553|M.smegmatis_MC2_155      LTSKQILDVQSGTGEFDVFDYFYFGLGDLVDADALVELTDWIDNRQGE--
MAV_2476|M.avium_104                GVMQQLSTFCVGGRCPDVLMAWELSYAELADRGVLLDLGPLLARDKAFAQ
                                               .    *:.          .    *  :            

Mflv_3775|M.gilvum_PYR-GCK          YDAGDFFTPLTDITT-VDGTRYGVP-FYNYALGYLYNADDLAAANQQ---
Mvan_2624|M.vanbaalenii_PYR-1       YDAADFFKPLTDITT-VDGARYGVP-FYNYALGYLYNADDLTAANQQ---
MMAR_3619|M.marinum_M               --PGEWEPAVVDQFT-RNGVLWGVPQLTDAGIAVFYNADLLAAAGVDPAE
MUL_1246|M.ulcerans_Agy99           --PGEWEPAVVDQFT-RNGVLWGVPQLTDAGIAVFYNADLLAAAGVDPAE
TH_2011|M.thermoresistible__bu      YDEDDFIPSIRESLS-YEGDMYAVP-FYGESSFLMYRKDLFEKSGIDMP-
MSMEG_0553|M.smegmatis_MC2_155      LDVSGYLKSIYDPYTLLDGKRYGLP-YDGDIHILFYNAELFDRYKVEP--
MAV_2476|M.avium_104                QLQADSIPALYETFT-FNGKQYALP-EQWSGNYLFYNKRLFDEAGVPSP-
                                            .: :  :  :*  :.:*         :*.   :         

Mflv_3775|M.gilvum_PYR-GCK          ------VPTTLDELVSTSKALKSGDRAGIAMQP--QRGYKIFEEWGN---
Mvan_2624|M.vanbaalenii_PYR-1       ------VPTTLDELVSTSKALKSGDRAGIAMQP--QRGYKIFEEWGN---
MMAR_3619|M.marinum_M               LDGLRWSPGPDDTLRALLARLTVDADGHVGGTP--GFDPGRVRQWGYNAA
MUL_1246|M.ulcerans_Agy99           LDGLRWSPGPDDTLRALLARLTVDADGHVGGTP--GFDPGRVRQWGYNAA
TH_2011|M.thermoresistible__bu      ------HNPTWQQVADAAAALDTPDMAGICLRG--KPGWGEVLAPLDT--
MSMEG_0553|M.smegmatis_MC2_155      -------PTTWDEYDEVAAKITKDARGTAYGAI--VSGQQVPMILGCSYI
MAV_2476|M.avium_104                -------PTAWERPWDFSEFLDTARALTKRDASGRAAQYGFVNTWGSYYS
                                             . :        :                             

Mflv_3775|M.gilvum_PYR-GCK          --------WLFAAGGSIYDADGKI-----TLNTP---EAKRALEAYIDTY
Mvan_2624|M.vanbaalenii_PYR-1       --------WLFAAGGSIYDADGKI-----TLNTP---EAKRALEAYIDTY
MMAR_3619|M.marinum_M               NDPQAIYLNYIGSAGGVFMRDNEF-----AFDNPPAIDAFRYLVGLINND
MUL_1246|M.ulcerans_Agy99           NDPQAIYLNYIGSAGGVFMRDNEF-----AFDNPPAIDAFRYLVGLINND
TH_2011|M.thermoresistible__bu      --------VINTFGGRWYDMDWNA-----QLDSP---EVEEAVSFYVNLV
MSMEG_0553|M.smegmatis_MC2_155      N-------RLTGYGGNLFDENGKP-----ALTSD----ASIAALEHLVAV
MAV_2476|M.avium_104                AG-------LFAMNNGVPWSDPRLNPTHFNFDNAAFQEAVQFYADLANKY
                                                  .     : .       : .     .           

Mflv_3775|M.gilvum_PYR-GCK          NTAAPANSLSWGMDEAQRSVSANQSASMINYNWQLPALNEPGSGPAAGKI
Mvan_2624|M.vanbaalenii_PYR-1       NTAAPANSLSWGMDEAQRSVSANQAASMINYNWQLPALNEPGSGPAAGKI
MMAR_3619|M.marinum_M               HVAPPASDTNDNGDFSRNQFLAGRMALFQSGTYSLAPVARDATFRWGVAM
MUL_1246|M.ulcerans_Agy99           HVAPPASDTNDNGDFSRNQFLAGRMALFQSGTYSLAPVARDATFRWGVAM
TH_2011|M.thermoresistible__bu      RDHGEPGPATSGFGECATQFAQGRAAMWYDATSAVSVLEDPAQSNVVGKV
MSMEG_0553|M.smegmatis_MC2_155      TPAALPTPLQIGFDQANTAFLSGQGAMLDTWTDMALRAEDPTASKIAGRW
MAV_2476|M.avium_104                RVAPNASETQS--MSTPNLFAVGRAAMALGGHWRYQTYLRAEGLDFDVAP
                                         .             .  .: *                        

Mflv_3775|M.gilvum_PYR-GCK          KLATIPGG---KQVLG----SWSWAIPANSATPDAAWAFVSWITAKP-ND
Mvan_2624|M.vanbaalenii_PYR-1       KLATIPGG---KQVLG----SWSWAIPANSATPDAAWAFVSWITAKP-ND
MMAR_3619|M.marinum_M               LPIGPAGR---VSVTN----GIAAAGNSASQHPDAVRQVLAWMGSSAGNE
MUL_1246|M.ulcerans_Agy99           LPIGPAGR---VSVTN----GIAAAGNSASQHPDAVRQVLAWMGSSAGNE
TH_2011|M.thermoresistible__bu      GYALAPTV---VKADAGWLYTWALGIPASSDNKDSAWKFISWMTDKNYIR
MSMEG_0553|M.smegmatis_MC2_155      GAVSLPVGGANTTPRTALDAGFGLGISTASENTDAAAAFIAWATAAPQNL
MAV_2476|M.avium_104                LPVGPAVG--KGQPACSDIGATGLAISSSSPRKEQAWEFVKFATGPVGQA
                                         .                . .  : *   : .  .: :        

Mflv_3775|M.gilvum_PYR-GCK          VVRTEK------GGAAIRKSTLQNPAVLQGQFG----------EEYYRTV
Mvan_2624|M.vanbaalenii_PYR-1       VVRTEK------GGAAIRQSTLQDPAVLGGQFG----------EEYYRTV
MMAR_3619|M.marinum_M               YLGRDG------VAIPAVRSAQPSYFAFWEAKG----------VNVEPFF
MUL_1246|M.ulcerans_Agy99           YLGRDG------VAIPAVRSAQPSYFAFWEAKG----------VNVNPFF
TH_2011|M.thermoresistible__bu      LVGEELGWARVPPGNRLSTYQIPEYQQASEAFGQVTLESLENADTQHPTV
MSMEG_0553|M.smegmatis_MC2_155      AVSSTAG-----AGIDPVRGEVLDSDGYAKVVT----------NAVAPIR
MAV_2476|M.avium_104                LIGESC------LFVPVLRSALKSDGFARAHRR----------VGNLGVL
                                     :                     .                          

Mflv_3775|M.gilvum_PYR-GCK          EQLLADAAPLTQGPSGEEMIQAVGTALNEAVAGEKSVDDALATAQAEAEK
Mvan_2624|M.vanbaalenii_PYR-1       EQLLANAAPLTQGPSGEEMIQAVGTELNEAVAGKKSVDDALAAAQAEAEK
MMAR_3619|M.marinum_M               AVLSGSRIPAPGGAGFAAGNDALKPYFDEMFLGRGQVATILREAQAAANA
MUL_1246|M.ulcerans_Agy99           AVLSGSRIPAPGGAGFAAGNDALKPYFDEMFLGRGQVATILREAQAAANA
TH_2011|M.thermoresistible__bu      QPVPYTGVQFLAIPEFQDLGTRVSQQISAAIAGQKSVKDALAQAQKYAQV
MSMEG_0553|M.smegmatis_MC2_155      QGLGGDPLVWPKQAGAPKLLQDLVDQLALAIAGTQTVEQSLEQAQASWDS
MAV_2476|M.avium_104                TDGPAFSQGLPITPAWEKVNALMDRNFGPILRGSRPATSLAGLSRSVDEV
                                                 .        :   :   . *   .      ::   : 

Mflv_3775|M.gilvum_PYR-GCK          IQG------
Mvan_2624|M.vanbaalenii_PYR-1       IQG------
MMAR_3619|M.marinum_M               AARR-----
MUL_1246|M.ulcerans_Agy99           AARR-----
TH_2011|M.thermoresistible__bu      VGKTYQEKP
MSMEG_0553|M.smegmatis_MC2_155      ASS------
MAV_2476|M.avium_104                LRSP-----

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_0553	-	-	100% (450)	sugar ABC transporter, substrate-binding protein, putative
M. smegmatis MC2 155	MSMEG_5574	-	2e-20	26.20% (439)	substrate binding protein
M. smegmatis MC2 155	MSMEG_3111	-	8e-17	22.74% (453)	extracellular solute-binding protein, family protein 1