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MLDRPFGRRSLLRGAGALSAAALAPWSAGCGSDDDGALTFFFAANPEERDARMRIIDEFARRHPDIKVRA VLSGPGVMQQLSTFCVGGRCPDVLMAWELSYAELADRGVLLDLGPLLARDKAFAQQLQADSIPALYETFT FNGKQYALPEQWSGNYLFYNKRLFDEAGVPSPPTAWERPWDFSEFLDTARALTKRDASGRAAQYGFVNTW GSYYSAGLFAMNNGVPWSDPRLNPTHFNFDNAAFQEAVQFYADLANKYRVAPNASETQSMSTPNLFAVGR AAMALGGHWRYQTYLRAEGLDFDVAPLPVGPAVGKGQPACSDIGATGLAISSSSPRKEQAWEFVKFATGP VGQALIGESCLFVPVLRSALKSDGFARAHRRVGNLGVLTDGPAFSQGLPITPAWEKVNALMDRNFGPILR GSRPATSLAGLSRSVDEVLRSP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2476 | - | - | 100% (442) | sugar ABC transporter, sugar-binding protein |
| M. avium 104 | MAV_2088 | - | 3e-13 | 28.17% (355) | extracellular solute-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2067c | - | 0.0 | 75.11% (442) | sugar-binding lipoprotein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2041c | - | 0.0 | 75.34% (442) | sugar-binding lipoprotein |
| M. leprae Br4923 | MLBr_01427 | - | 0.0 | 77.10% (441) | putative ABC-transport lipoprotein |
| M. abscessus ATCC 19977 | MAB_1715c | - | 6e-18 | 27.55% (323) | sugar ABC transporter, sugar-binding protein |
| M. marinum M | MMAR_3014 | - | 0.0 | 73.08% (442) | sugar-binding lipoprotein |
| M. smegmatis MC2 155 | MSMEG_4468 | - | 8e-20 | 28.57% (336) | extracellular solute-binding protein UspC |
| M. thermoresistible (build 8) | TH_2011 | - | 6e-15 | 25.00% (364) | substrate binding protein |
| M. ulcerans Agy99 | MUL_1246 | uspC | 6e-14 | 26.95% (334) | periplasmic sugar-binding lipoprotein UspC |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4468|M.smegmatis_MC2_155 MRR---STLLAGGLAVTMAVLLVIAMLMGRTTEPAG-KTVVTVRLWDPQV
MUL_1246|M.ulcerans_Agy99 MNRPRFSTLVAVAVTLIAALLGVTAVALDRIDAPPGGKIVVTVRLWAAPI
MAB_1715c|M.abscessus_ATCC_199 MKA---STRAALTLALVALLLFGVAAWLGIPTTPHG-KTVVTVRVWDQQV
MAV_2476|M.avium_104 MLDRPFGRRSLLRGAGALSAAALAPWSAGCGSDDDG--ALTFFFAANPEE
MLBr_01427|M.leprae_Br4923 MHGKLFGRRSLLRGAGALTAAALAPGAVGCSSDDD---ALTFFFAANPEE
Mb2067c|M.bovis_AF2122/97 MVNKPFERRSLLRGAGALTAASLAPWAAGCAADDDD--ALTFFFAANPDE
Rv2041c|M.tuberculosis_H37Rv MVNKPFERRSLLRGAGALTAASLAPWAAGCAADDDD--ALTFFFAANPDE
MMAR_3014|M.marinum_M MFDKPLRRRELLRGAGLLTAAALAPVAAGCASDDD---ALTFFFAANPEE
TH_2011|M.thermoresistible__bu --VRRTPIRAVLAAVAAVCLTLTGCAGAGTLGSSGN--TVTIALVSNSQM
. . :.
MSMEG_4468|M.smegmatis_MC2_155 AAAYRESFDAFSAEHPGIEVRVNTVAYA-SYFDSLRTDVAGGSADDIFWI
MUL_1246|M.ulcerans_Agy99 AAAYQQSFAAFSRTHPNIEVHTNLVSFS-TYFDTLRTDVAGGSADDIFWL
MAB_1715c|M.abscessus_ATCC_199 AEAYRGSFDEFSRRNPDIQVAVTVTSYA-SYFNSLRTDVAGHGADDIFWL
MAV_2476|M.avium_104 RDARMRIIDEFARRHPDIKVRA-VLSGP-GVMQQLSTFCVGGRCPDVLMA
MLBr_01427|M.leprae_Br4923 TNARMRIVGEFQRDHPDIKVRA-VLSGP-GVMQQLSTFCAGGKCPDVLMA
Mb2067c|M.bovis_AF2122/97 LRPRMRVVNEFQRRYPDIKVRA-LLSGP-GVMQQLATFCAGGKCPDVLMA
Rv2041c|M.tuberculosis_H37Rv LRPRMRVVNEFQRRYPDIKVRA-LLSGP-GVMQQLATFCAGGKCPDVLMA
MMAR_3014|M.marinum_M ADARIRVVDAFGRSHPDIKVRT-LLSGP-GALQQISTFCAGGKCPDVLMA
TH_2011|M.thermoresistible__bu SDAQR-LAPHFEAANPDIRLKFVTLSENQARAKITASTAMGGGEFDVVMI
. * *.*.: : . : * *:.
MSMEG_4468|M.smegmatis_MC2_155 SNGYFAGYADNGHLLDIADLLGPDA------ATAWEPSVVEQFTRNGALW
MUL_1246|M.ulcerans_Agy99 SNAYLAAYADSGRLMKIDTAVDP---------GEWEPAVVDQFTRNGVLW
MAB_1715c|M.abscessus_ATCC_199 SNAYLSDYADTGNLVPVEP------------RADWDPSVVAQFTRDGKLW
MAV_2476|M.avium_104 WELSYAELADRGVLLDLGPLLARDKAFAQQLQADSIPALYETFTFNGKQY
MLBr_01427|M.leprae_Br4923 WDLTYAELADRGVLLDLNTLLGQDKAFAAELKSDSIEPLYETFTFNGGQY
Mb2067c|M.bovis_AF2122/97 WELTYAELADRGVLLDLNTLLARDQVFAAELKSDSIGALYETFTFNGGQY
Rv2041c|M.tuberculosis_H37Rv WELTYAELADRGVLLDLNTLLARDQAFAAELKSDSIGALYETFTFNGGQY
MMAR_3014|M.marinum_M WELSYAELADRGVFLDLNTMLARDQKFADELAADSIGALYDTFAYNGGQY
TH_2011|M.thermoresistible__bu SNYETPQWAADGWLVNLSDYARQTPGYD---EDDFIPSIRESLSYEGDMY
: . * * :: : .: :: :* :
MSMEG_4468|M.smegmatis_MC2_155 GVPQLTDAGIAVYYNADLLEKAGVSPAD-LSTLR-WSNGPD-DTLRPLLA
MUL_1246|M.ulcerans_Agy99 GVPQLTDAGIAVFYNADLLAAAGVDPAE-LDGLR-WSPGPD-DTLRALLA
MAB_1715c|M.abscessus_ATCC_199 GVPQLSDAGIALYYNKNLLDAAQVDPAE-LAELR-WDPDPEVDTLRPMLH
MAV_2476|M.avium_104 ALPEQWSG-NYLFYNKRLFDEAGVPSPP-TAWERPWDFSEFLDTARALTK
MLBr_01427|M.leprae_Br4923 AFPEQWSG-NYLFYNKQLFTNAGVQPPP-CTWEQPWSFTEFLDTARALTK
Mb2067c|M.bovis_AF2122/97 AFPEQWSG-NFLFYNKQLFDDAGVPPPP-GSWERPWSFAEFLDAAQALTK
Rv2041c|M.tuberculosis_H37Rv AFPEQWSG-NFLFYNKQLFDDAGVPPPP-GSWERPWSFAEFLDAAQALTK
MMAR_3014|M.marinum_M AFPEQWSG-NFLFYNRGLFADGGVPPPP-TSWDQPWSFAEFLDTARALTK
TH_2011|M.thermoresistible__bu AVPFYGES-SFLMYRKDLFEKSGIDMPHNPTWQQVADAAAALDTPDMAGI
..* .. : *. *: . : . : . *:
MSMEG_4468|M.smegmatis_MC2_155 RLTVEES-----------GRTRQWGYNAANDLQGIYLNFIGSAGGTFS--
MUL_1246|M.ulcerans_Agy99 RLTVDADGHVGGTPGFDPGRVRQWGYNAANDPQAIYLNYIGSAGGVFM--
MAB_1715c|M.abscessus_ATCC_199 RLTAPGH----------------WGYNAANDLQGIYLNYLGSAGAVFQ--
MAV_2476|M.avium_104 RDASGRA--------------AQYGFVNTWGSYYSAGLFAMNNGVPWSDP
MLBr_01427|M.leprae_Br4923 RDSSGRV--------------TQWGFVNTWLSYYTAGLFALNNGVPWSNP
Mb2067c|M.bovis_AF2122/97 QGRSGRD--------------RQWGFVNAWVSFYAAGLFAMNNGVPWSVP
Rv2041c|M.tuberculosis_H37Rv QGRSGRD--------------RQWGFVNAWVSFYAAGLFAMNNGVPWSVP
MMAR_3014|M.marinum_M RDGAGRV--------------TQWGFVDTFVPPLSAGLFALNNGVPWSTP
TH_2011|M.thermoresistible__bu CLRGKPG----------------WGEVLAPLDTVINTFGGRWYDMDWN--
:* : . :
MSMEG_4468|M.smegmatis_MC2_155 --EGDRFTFDNPQAVEAFEYLVRLINTDRVAPPASDTNDNGDFSRNAFLA
MUL_1246|M.ulcerans_Agy99 --RDNEFAFDNPPAIDAFRYLVGLINNDHVAPPASDTNDNGDFSRNQFLA
MAB_1715c|M.abscessus_ATCC_199 --ADDKFAFAKPRAEMAFTYLVDLINVDRVAPSAADTNDNNDFSRNQFLQ
MAV_2476|M.avium_104 RLNPTHFNFDNAAFQEAVQFYADLANKYRVAPNASETQSMS--TPNLFAV
MLBr_01427|M.leprae_Br4923 RMNPTHLNFDDDAFIEAVQFYCDLTNKYQVAPDASEQQWMA--TADLFSL
Mb2067c|M.bovis_AF2122/97 RMNPTHLNFDHDGFLEAVQFYADLTNKHKVAPSAAEQQSMS--TADLFSV
Rv2041c|M.tuberculosis_H37Rv RMNPTHLNFDHDGFLEAVQFYADLTNKHKVAPSAAEQQSMS--TADLFSV
MMAR_3014|M.marinum_M RMNPTHLNFDDDAFIEAVQFYADLSAKHQVAPTASELQSIA--TTDLFSL
TH_2011|M.thermoresistible__bu ------AQLDSPEVEEAVSFYVNLVRDHGEPGPATSGFGEC---ATQFAQ
: *. : * . *:. *
MSMEG_4468|M.smegmatis_MC2_155 GRMALFQSGTYNLAAIAD-QAPFPWGVAMLPIGPKGR---------VSVT
MUL_1246|M.ulcerans_Agy99 GRMALFQSGTYSLAPVAR-DATFRWGVAMLPIGPAGR---------VSVT
MAB_1715c|M.abscessus_ATCC_199 GRMALFQSGTYNLAQIQA-NATFPWDVAMMPAGPQGR---------VSVT
MAV_2476|M.avium_104 GRAAMALGGHWRYQTYLR-AEGLDFDVAPLPVGPAVG----KGQPACSDI
MLBr_01427|M.leprae_Br4923 GKAAIALGGHWRYQTFMR-AEGLDFDVTSLPIGPSAGTVPATRSGACSDI
Mb2067c|M.bovis_AF2122/97 GKAGIALAGHWRYQTFDR-ADGLDFDVAPLPIGPRGR-------AACSDI
Rv2041c|M.tuberculosis_H37Rv GKAGIALAGHWRYQTFDR-ADGLDFDVAPLPIGPRGR-------AACSDI
MMAR_3014|M.marinum_M GKAAMALGGHWRYQTFDR-ADGLEFDVTALPLGPNGR-------AACSNI
TH_2011|M.thermoresistible__bu GRAAMWYDATSAVSVLEDPAQSNVVGKVGYALAPTVVK------ADAGWL
*: .: . . . . .* .
MSMEG_4468|M.smegmatis_MC2_155 NGIAAAGNAATRHPEAVREVLAWMGSRRGNEFVGRRG-------------
MUL_1246|M.ulcerans_Agy99 NGIAAAGNSASQHPDAVRQVLAWMGSSAGNEYLGRDG-------------
MAB_1715c|M.abscessus_ATCC_199 NGIVAAANSSSPHPDAVHKVLAWMGSTDGNSFLGRSG-------------
MAV_2476|M.avium_104 GATGLAISSSSPRKEQAWEFVKFATGPVGQALIGESC-------------
MLBr_01427|M.leprae_Br4923 GATGLAIAASSSRKEQAWEFVKFATGPAGQALIGESC-------------
Mb2067c|M.bovis_AF2122/97 GVTGLAIAATSRRKDQAWEFVKFATGPVGQALIGESR-------------
Rv2041c|M.tuberculosis_H37Rv GVTGLAIAATSRRKDQAWEFVKFATGPVGQALIGESR-------------
MMAR_3014|M.marinum_M GATGLAIAASSARKEQAWEFVKFATGPAGQALIGETD-------------
TH_2011|M.thermoresistible__bu YTWALGIPASSDNKDSAWKFISWMTDKNYIRLVGEELGWARVPPGNRLST
. ::: . : . :.: : . :*.
MSMEG_4468|M.smegmatis_MC2_155 AAIPAVLAAQPVY---HEYWASRGVDVSPFFRVLQGPRIAAPGGAGFPAG
MUL_1246|M.ulcerans_Agy99 VAIPAVRSAQPSY---FAFWEAKGVNVNPFFAVLSGSRIPAPGGAGFAAG
MAB_1715c|M.abscessus_ATCC_199 SAIPAVLSARAPY---FQYWADKGVDVSPFFEVLRGQQIAAPGGQGFGAG
MAV_2476|M.avium_104 LFVPVLRSALKSD---GFARAHRRVGNLGVLTDGPAFSQGLPITPAWEKV
MLBr_01427|M.leprae_Br4923 LFVPVLQSAIYST---GFAKAHNRVANLAVLTGGPVHSAGLPITPAWEKI
Mb2067c|M.bovis_AF2122/97 LFVPVLRSAINSH---GFANAHRRVGNLAVLSEGPAYSEGLPVTPAWEKI
Rv2041c|M.tuberculosis_H37Rv LFVPVLRSAINSH---GFANAHRRVGNLAVLSEGPAYSEGLPVTPAWEKI
MMAR_3014|M.marinum_M LFVPVLGSALNSA---GFAKAHRRVDNLAVLTAGPGHSQGLPITPAWPKV
TH_2011|M.thermoresistible__bu YQIPEYQQASEAFGQVTLESLENADTQHPTVQPVPYTGVQFLAIPEFQDL
:* * . . :
MSMEG_4468|M.smegmatis_MC2_155 FEALTPYFAEMFLGRRDVAGTLAEAQRAANAAASR-----
MUL_1246|M.ulcerans_Agy99 NDALKPYFDEMFLGRGQVATILREAQAAANAAARR-----
MAB_1715c|M.abscessus_ATCC_199 FAALKPYFAEMFLGRLDVREALQQAQRAANRALER-----
MAV_2476|M.avium_104 NALMDRNFGPILRGSRPATSLAGLSRSVDEVLRSP-----
MLBr_01427|M.leprae_Br4923 NALMDRNFGPVLRGVRPATSLAGLARAVDEVLNSP-----
Mb2067c|M.bovis_AF2122/97 AALMDRYFGPVLRGSRPATSLTGLSQAVDEVLRNP-----
Rv2041c|M.tuberculosis_H37Rv AALMDRYFGPVLRGSRPATSLTGLSQAVDEVLRNP-----
MMAR_3014|M.marinum_M HALMDRNFGPVLRGSRPATSLIGMSRALDEVLRSP-----
TH_2011|M.thermoresistible__bu GTRVSQQISAAIAGQKSVKDALAQAQKYAQVVGKTYQEKP
: : : * . :: :