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KIPQLRRRRRRPAITAITAMSVAAGLVLSGCAGTGGPANDEATSGVGDVPTDTSATVRVLMENVPDTDIV QGLVGQFNEKYPDIKVDIETMTFDQMRDRLVSSFQAAQPAYDLIVVDNPWMDDFADAGFLQPLDERIAAT TDFRPDDFFPSLTDITDVDGTTYGVPFYNYALGYIYNKDDLAAAGASVPTDLDALVRTSQQLKTADRAGI AMQPQRGYKIFEEWANWLFAAGGSIYDKDGNPTLDTEQAARALDAYIETYRTAAPANSLAWGFDEAFRSV SSGKAASMVGYNWNLPALNDPAGASGERAGQFALAPIPGGKSALGLWSWAIPANSAASDAAWAFISWITS PEIDAERVAKGGAVVRESSLTNEKVLKDGYGEDYYRVVGEILSDAAPLTQGKGGEEMIQAVGTELNDAAA GNKSVADALRDAQAAVERIQK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3111 | - | - | 100% (442) | extracellular solute-binding protein, family protein 1 |
| M. smegmatis MC2 155 | MSMEG_5574 | - | 1e-32 | 27.03% (444) | substrate binding protein |
| M. smegmatis MC2 155 | MSMEG_0553 | - | 8e-17 | 22.74% (453) | sugar ABC transporter, substrate-binding protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2857c | ugpB | 5e-12 | 26.61% (357) | sn-glycerol-3-phosphate-binding lipoprotein UGPB |
| M. gilvum PYR-GCK | Mflv_3775 | - | 1e-166 | 66.36% (434) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv2833c | ugpB | 5e-12 | 26.61% (357) | sn-glycerol-3-phosphate-binding lipoprotein UGPB |
| M. leprae Br4923 | MLBr_01427 | - | 2e-09 | 22.91% (419) | putative ABC-transport lipoprotein |
| M. abscessus ATCC 19977 | MAB_1715c | - | 4e-06 | 29.32% (133) | sugar ABC transporter, sugar-binding protein |
| M. marinum M | MMAR_3619 | uspC | 7e-10 | 23.75% (459) | periplasmic sugar-binding lipoprotein UspC |
| M. avium 104 | MAV_2476 | - | 2e-09 | 23.36% (411) | sugar ABC transporter, sugar-binding protein |
| M. thermoresistible (build 8) | TH_2011 | - | 1e-33 | 26.58% (459) | substrate binding protein |
| M. ulcerans Agy99 | MUL_1246 | uspC | 5e-10 | 23.75% (459) | periplasmic sugar-binding lipoprotein UspC |
| M. vanbaalenii PYR-1 | Mvan_2624 | - | 1e-165 | 65.68% (440) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3619|M.marinum_M ---MSRPRFSTLVAV---------AVTLIAALLGVTAVALDR--------
MUL_1246|M.ulcerans_Agy99 ---MNRPRFSTLVAV---------AVTLIAALLGVTAVALDR--------
MAB_1715c|M.abscessus_ATCC_199 ------MKASTRAAL---------TLALVALLLFGVAAWLG---------
Mb2857c|M.bovis_AF2122/97 -----MDPLNRRQFL---------ALAAAAAGVTAGCAGMGG--------
Rv2833c|M.tuberculosis_H37Rv -----MDPLNRRQFL---------ALAAAAAGVTAGCAGMGG--------
MLBr_01427|M.leprae_Br4923 ---MHGKLFGRR------------SLLRGAGALTAAALAPGA--------
MAV_2476|M.avium_104 ---MLDRPFGRR------------SLLRGAGALSAAALAPWS--------
Mflv_3775|M.gilvum_PYR-GCK MRFAQIPT-ARRGGK--TARSAVLALLAVLALVLSACAGSGGPEQAEST-
Mvan_2624|M.vanbaalenii_PYR-1 MRITQWPTSGRRSGRPGTAFSAVMALVAVLALVLTGCAGSGGPEQAEAT-
MSMEG_3111|M.smegmatis_MC2_155 ---MKIPQLRRRRRR--PAITAITAMSVAAGLVLSGCAGTGGPANDEATS
TH_2011|M.thermoresistible__bu --------VRRTPIR---------AVLAAVAAVCLTLTGCAG--------
:: :
MMAR_3619|M.marinum_M -IDAPPGGKIVVTVRLWAAP-IAAAYQQSFAAFSRTHPNIEVHTNLVSFS
MUL_1246|M.ulcerans_Agy99 -IDAPPGGKIVVTVRLWAAP-IAAAYQQSFAAFSRTHPNIEVHTNLVSFS
MAB_1715c|M.abscessus_ATCC_199 -IPTTPHGKTVVTVRVWDQQ-VAEAYRGSFDEFSRRNPDIQVAVTVTSYA
Mb2857c|M.bovis_AF2122/97 -GGSVKSGSGPIDFWSSHPGQSSAAERELIGRFQDRFPTLSVKLIDAGKD
Rv2833c|M.tuberculosis_H37Rv -GGSVKSGSGPIDFWSSHPGQSSAAERELIGRFQDRFPTLSVKLIDAGKD
MLBr_01427|M.leprae_Br4923 -VGCSSDDD-ALTFFFAANPEETNARMRIVGEFQRDHPDIKVRAVLSGPG
MAV_2476|M.avium_104 -AGCGSDDDGALTFFFAANPEERDARMRIIDEFARRHPDIKVRAVLSGPG
Mflv_3775|M.gilvum_PYR-GCK GSGEVSADTSGTVRILMENVPDTDIVKSMVADFNAEYPGVEINIESLTFD
Mvan_2624|M.vanbaalenii_PYR-1 GTGEVSTDVSGTVRILMENVPDTDIVKSMVADFNKEYPGVEINIESLTFD
MSMEG_3111|M.smegmatis_MC2_155 GVGDVPTDTSATVRVLMENVPDTDIVQGLVGQFNEKYPDIKVDIETMTFD
TH_2011|M.thermoresistible__bu -AGTLGSSGNTVTIALVSNSQMSDAQR-LAPHFEAANPDIRLKFVTLSEN
. * * : :
MMAR_3619|M.marinum_M T--YFDTLRTDVAGGSADDIFWLSNAYLAAYADSGRLMKIDTAVDP----
MUL_1246|M.ulcerans_Agy99 T--YFDTLRTDVAGGSADDIFWLSNAYLAAYADSGRLMKIDTAVDP----
MAB_1715c|M.abscessus_ATCC_199 S--YFNSLRTDVAGHGADDIFWLSNAYLSDYADTGNLVPVEPRAD-----
Mb2857c|M.bovis_AF2122/97 YDEVAQKFNAALIGTDVPDVVLLDDRWWFHFALIGVLTALDDLFGQ----
Rv2833c|M.tuberculosis_H37Rv YDEVAQKFNAALIGTDVPDVVLLDDRWWFHFALSGVLTALDDLFGQ----
MLBr_01427|M.leprae_Br4923 ---VMQQLSTFCAGGKCPDVLMAWDLTYAELADRGVLLDLNTLLGQDKAF
MAV_2476|M.avium_104 ---VMQQLSTFCVGGRCPDVLMAWELSYAELADRGVLLDLGPLLARDKAF
Mflv_3775|M.gilvum_PYR-GCK Q-MRDKLVSSFQSSSPAYDLIVVDNPWMVDFANAKFLQPLDARIDSTP--
Mvan_2624|M.vanbaalenii_PYR-1 Q-MRDKLVSSFQSSSPTYDLIVVDNPWMVDFANAKFLQPLDARIDSTP--
MSMEG_3111|M.smegmatis_MC2_155 Q-MRDRLVSSFQAAQPAYDLIVVDNPWMDDFADAGFLQPLDERIAATT--
TH_2011|M.thermoresistible__bu Q-ARAKITASTAMGGGEFDVVMISNYETPQWAADGWLVNLSDYARQTP--
: . *:. : * * :
MMAR_3619|M.marinum_M -----GEWEPAVVDQFTRNGVLWGVPQLTDAGIAVFYNADLLAAAGVDPA
MUL_1246|M.ulcerans_Agy99 -----GEWEPAVVDQFTRNGVLWGVPQLTDAGIAVFYNADLLAAAGVDPA
MAB_1715c|M.abscessus_ATCC_199 -------WDPSVVAQFTRDGKLWGVPQLSDAGIALYYNKNLLDAAQVDPA
Mb2857c|M.bovis_AF2122/97 VGVDTTDYVDSLLADYEFNGRHYAVPYARST-PLFYYNKAAWQQAGLPD-
Rv2833c|M.tuberculosis_H37Rv VGVDTTDYVDSLLADYEFNGRHYAVPYARST-PLFYYNKAAWQQAGLPD-
MLBr_01427|M.leprae_Br4923 AAELKSDSIEPLYETFTFNGGQYAFPEQWSG-NYLFYNKQLFTNAGVQPP
MAV_2476|M.avium_104 AQQLQADSIPALYETFTFNGKQYALPEQWSG-NYLFYNKRLFDEAGVPSP
Mflv_3775|M.gilvum_PYR-GCK -DYDAGDFFTPLTDITTVDGTRYGVPFYNYALGYLYNADDLAAANQQVPT
Mvan_2624|M.vanbaalenii_PYR-1 -DYDAADFFKPLTDITTVDGARYGVPFYNYALGYLYNADDLTAANQQVPT
MSMEG_3111|M.smegmatis_MC2_155 -DFRPDDFFPSLTDITDVDGTTYGVPFYNYALGYIYNKDDLAAAGASVPT
TH_2011|M.thermoresistible__bu -GYDEDDFIPSIRESLSYEGDMYAVPFYGES-SFLMYRKDLFEKSGIDMP
.: :* :..* .
MMAR_3619|M.marinum_M ELDGLRWSPGPD-DTLRALLARLTVDADGHVGGTPGFDPGRVRQWGYNAA
MUL_1246|M.ulcerans_Agy99 ELDGLRWSPGPD-DTLRALLARLTVDADGHVGGTPGFDPGRVRQWGYNAA
MAB_1715c|M.abscessus_ATCC_199 ELAELRWDPDPEVDTLRPMLHRLTA---------PG-------HWGYNAA
Mb2857c|M.bovis_AF2122/97 ----RGLQSWSEFDEWGPELQRVVG---------AGRSAHG-----WANA
Rv2833c|M.tuberculosis_H37Rv ----RGPQSWSEFDEWGPELQRVVG---------AGRSAHG-----WANA
MLBr_01427|M.leprae_Br4923 PCTWEQPWSFTEFLDTARALTKRDS---------SGRVTQWGFVNTWLSY
MAV_2476|M.avium_104 PTAWERPWDFSEFLDTARALTKRDA---------SGRAAQYGFVNTWGSY
Mflv_3775|M.gilvum_PYR-GCK TLDELVSTSKALKSGDRAGIAMQPQ----------------------RGY
Mvan_2624|M.vanbaalenii_PYR-1 TLDELVSTSKALKSGDRAGIAMQPQ----------------------RGY
MSMEG_3111|M.smegmatis_MC2_155 DLDALVRTSQQLKTADRAGIAMQPQ----------------------RGY
TH_2011|M.thermoresistible__bu HNPTWQQVADAAAALDTPDMAGICLR------------------GKPGWG
:
MMAR_3619|M.marinum_M NDPQAIYLNYIGSAGGVFMRDNEFAFDNPPAIDAFRYLVGLINNDHVAPP
MUL_1246|M.ulcerans_Agy99 NDPQAIYLNYIGSAGGVFMRDNEFAFDNPPAIDAFRYLVGLINNDHVAPP
MAB_1715c|M.abscessus_ATCC_199 NDLQGIYLNYLGSAGAVFQADDKFAFAKPRAEMAFTYLVDLINVDRVAPS
Mb2857c|M.bovis_AF2122/97 DLISWTFQGPNWAFGGAYSDKWTLTLTEPATIAAGNFYRNSIHGKGYAAV
Rv2833c|M.tuberculosis_H37Rv DLISWTFQGPNWAFGGAYSDKWTLTLTEPATIAAGNFYRNSIHGKGYAAV
MLBr_01427|M.leprae_Br4923 YTAGLFALNNGVPWSNPRMNPTHLNFDDDAFIEAVQFYCDLTNKYQVAPD
MAV_2476|M.avium_104 YSAGLFAMNNGVPWSDPRLNPTHFNFDNAAFQEAVQFYADLANKYRVAPN
Mflv_3775|M.gilvum_PYR-GCK KIFEEWGNWLFAAGGSIYDADGKITLNTPEAKRALEAYIDTYN---TAAP
Mvan_2624|M.vanbaalenii_PYR-1 KIFEEWGNWLFAAGGSIYDADGKITLNTPEAKRALEAYIDTYN---TAAP
MSMEG_3111|M.smegmatis_MC2_155 KIFEEWANWLFAAGGSIYDKDGNPTLDTEQAARALDAYIETYR---TAAP
TH_2011|M.thermoresistible__bu EVLAPLDTVINTFGGRWYDMDWNAQLDSPEVEEAVSFYVNLVRDHGEPGP
. : * . .
MMAR_3619|M.marinum_M ASDTNDNGDFSRNQFLAGRMALFQSGTYSLAPVARDAT----FRWGVAML
MUL_1246|M.ulcerans_Agy99 ASDTNDNGDFSRNQFLAGRMALFQSGTYSLAPVARDAT----FRWGVAML
MAB_1715c|M.abscessus_ATCC_199 AADTNDNNDFSRNQFLQGRMALFQSGTYNLAQIQANAT----FPWDVAMM
Mb2857c|M.bovis_AF2122/97 AN-------DIANEFATGILASAVASTGSLPGITASAR----FDFGAAPL
Rv2833c|M.tuberculosis_H37Rv AN-------DIANEFATGILASAVASTGSLAGITASAR----FDFGAAPL
MLBr_01427|M.leprae_Br4923 ASEQQWM--ATADLFSLGKAAIALGGHWRYQTFMRAEG----LDFDVTSL
MAV_2476|M.avium_104 ASETQSM--STPNLFAVGRAAMALGGHWRYQTYLRAEG----LDFDVAPL
Mflv_3775|M.gilvum_PYR-GCK ANSLSWGMDEAQRSVSANQSASMINYNWQLPALNEPG---SGPAAGKIKL
Mvan_2624|M.vanbaalenii_PYR-1 ANSLSWGMDEAQRSVSANQAASMINYNWQLPALNEPG---SGPAAGKIKL
MSMEG_3111|M.smegmatis_MC2_155 ANSLAWGFDEAFRSVSSGKAASMVGYNWNLPALNDPAGA-SGERAGQFAL
TH_2011|M.thermoresistible__bu ATS---GFGECATQFAQGRAAMWYDATSAVSVLEDPAQSNVVGKVGYALA
* . . * .
MMAR_3619|M.marinum_M PIGPAGR-----------VSVTNGIAAAGNSASQHPDAVRQVLAWMGSSA
MUL_1246|M.ulcerans_Agy99 PIGPAGR-----------VSVTNGIAAAGNSASQHPDAVRQVLAWMGSSA
MAB_1715c|M.abscessus_ATCC_199 PAGPQGR-----------VSVTNGIVAAANSSSPHPDAVHKVLAWMGSTD
Mb2857c|M.bovis_AF2122/97 PTGPDAA-------PACP-TGGAGLAIPAKLSEERKVNALKFIAFVTNPT
Rv2833c|M.tuberculosis_H37Rv PTGPDAA-------PACP-TGGAGLAIPAKLSEERKVNALKFIAFVTNPT
MLBr_01427|M.leprae_Br4923 PIGPSAGTVPATRSGACSDIGATGLAIAA--SSSRKEQAWEFVKFATGPA
MAV_2476|M.avium_104 PVGPAVG----KGQPACSDIGATGLAISS--SSPRKEQAWEFVKFATGPV
Mflv_3775|M.gilvum_PYR-GCK ATIPGGK------------QVLGSWSWAIPANSATPDAAWAFVSWITAKP
Mvan_2624|M.vanbaalenii_PYR-1 ATIPGGK------------QVLGSWSWAIPANSATPDAAWAFVSWITAKP
MSMEG_3111|M.smegmatis_MC2_155 APIPGGK------------SALGLWSWAIPANSAASDAAWAFISWITSPE
TH_2011|M.thermoresistible__bu PTVVKAD-----------AGWLYTWALGIPASSDNKDSAWKFISWMTDKN
. . . .: :
MMAR_3619|M.marinum_M GNEYLGRDG--VAIPAVRSAQPSY-FAFWEAKGVNVEPFFAVLSGSRIPA
MUL_1246|M.ulcerans_Agy99 GNEYLGRDG--VAIPAVRSAQPSY-FAFWEAKGVNVNPFFAVLSGSRIPA
MAB_1715c|M.abscessus_ATCC_199 GNSFLGRSG--SAIPAVLSARAPY-FQYWADKGVDVSPFFEVLRGQQIAA
Mb2857c|M.bovis_AF2122/97 NTAYFSQQT--GYLPVRKSAVDDASERHYLADNPRARVALDQLPHTRTQD
Rv2833c|M.tuberculosis_H37Rv NTAYFSQQT--GYLPVRKSAVDDASERHYLADNPRARVALDQLPHTRTQD
MLBr_01427|M.leprae_Br4923 GQALIGESC--LFVPVLQSAIYST----GFAKAHNRVANLAVLTGGPVHS
MAV_2476|M.avium_104 GQALIGESC--LFVPVLRSALKSD----GFARAHRRVGNLGVLTDGPAFS
Mflv_3775|M.gilvum_PYR-GCK NDVVRTEKG--GAAIRKSTLQNPA-----VLQGQFGEEYYRTVEQLLADA
Mvan_2624|M.vanbaalenii_PYR-1 NDVVRTEKG--GAAIRQSTLQDPA-----VLGGQFGEEYYRTVEQLLANA
MSMEG_3111|M.smegmatis_MC2_155 IDAERVAKG--GAVVRESSLTNEK-----VLKDGYGEDYYRVVGEILSDA
TH_2011|M.thermoresistible__bu YIRLVGEELGWARVPPGNRLSTYQIPEYQQASEAFGQVTLESLENADTQH
. :
MMAR_3619|M.marinum_M PGGA----------GFAAGNDALKPYFDEMF--LGRGQ-VATILREAQAA
MUL_1246|M.ulcerans_Agy99 PGGA----------GFAAGNDALKPYFDEMF--LGRGQ-VATILREAQAA
MAB_1715c|M.abscessus_ATCC_199 PGGQ----------GFGAGFAALKPYFAEMF--LGRLD-VREALQQAQRA
Mb2857c|M.bovis_AF2122/97 YARV----------FLPGGDRIISAGLESIG--LRGAD-VTKTFTNIQKR
Rv2833c|M.tuberculosis_H37Rv YARV----------FLPGGDRIISAGLESIG--LRGAD-VTKTFTNIQKR
MLBr_01427|M.leprae_Br4923 AGLP----------ITPAWEKINALMDRNFGPVLRGVR-PATSLAGLARA
MAV_2476|M.avium_104 QGLP----------ITPAWEKVNALMDRNFGPILRGSR-PATSLAGLSRS
Mflv_3775|M.gilvum_PYR-GCK APLT----------QGPSGEEMIQAVGTALNEAVAGEKSVDDALATAQAE
Mvan_2624|M.vanbaalenii_PYR-1 APLT----------QGPSGEEMIQAVGTELNEAVAGKKSVDDALAAAQAE
MSMEG_3111|M.smegmatis_MC2_155 APLT----------QGKGGEEMIQAVGTELNDAAAGNKSVADALRDAQAA
TH_2011|M.thermoresistible__bu PTVQPVPYTGVQFLAIPEFQDLGTRVSQQISAAIAGQKSVKDALAQAQKY
: :
MMAR_3619|M.marinum_M ANAAARR----------
MUL_1246|M.ulcerans_Agy99 ANAAARR----------
MAB_1715c|M.abscessus_ATCC_199 ANRALER----------
Mb2857c|M.bovis_AF2122/97 LQVILDRQIMRKLAGHG
Rv2833c|M.tuberculosis_H37Rv LQVILDRQIMRKLAGHG
MLBr_01427|M.leprae_Br4923 VDEVLNSP---------
MAV_2476|M.avium_104 VDEVLRSP---------
Mflv_3775|M.gilvum_PYR-GCK AEKIQG-----------
Mvan_2624|M.vanbaalenii_PYR-1 AEKIQG-----------
MSMEG_3111|M.smegmatis_MC2_155 VERIQK-----------
TH_2011|M.thermoresistible__bu AQVVGKTYQEKP-----
: