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KASTRAALTLALVALLLFGVAAWLGIPTTPHGKTVVTVRVWDQQVAEAYRGSFDEFSRRNPDIQVAVTVT SYASYFNSLRTDVAGHGADDIFWLSNAYLSDYADTGNLVPVEPRADWDPSVVAQFTRDGKLWGVPQLSDA GIALYYNKNLLDAAQVDPAELAELRWDPDPEVDTLRPMLHRLTAPGHWGYNAANDLQGIYLNYLGSAGAV FQADDKFAFAKPRAEMAFTYLVDLINVDRVAPSAADTNDNNDFSRNQFLQGRMALFQSGTYNLAQIQANA TFPWDVAMMPAGPQGRVSVTNGIVAAANSSSPHPDAVHKVLAWMGSTDGNSFLGRSGSAIPAVLSARAPY FQYWADKGVDVSPFFEVLRGQQIAAPGGQGFGAGFAALKPYFAEMFLGRLDVREALQQAQRAANRALER*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1715c | - | - | 100% (420) | sugar ABC transporter, sugar-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2345 | uspC | 1e-148 | 61.78% (437) | periplasmic sugar-binding lipoprotein UspC |
| M. gilvum PYR-GCK | Mflv_3775 | - | 4e-06 | 21.33% (450) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv2318 | uspC | 1e-148 | 62.01% (437) | periplasmic sugar-binding lipoprotein UspC |
| M. leprae Br4923 | MLBr_01770 | uspC | 1e-138 | 57.60% (441) | sugar transport periplasmic binding protein |
| M. marinum M | MMAR_3619 | uspC | 1e-141 | 60.41% (437) | periplasmic sugar-binding lipoprotein UspC |
| M. avium 104 | MAV_2088 | - | 1e-147 | 62.50% (440) | extracellular solute-binding protein |
| M. smegmatis MC2 155 | MSMEG_4468 | - | 1e-150 | 62.41% (431) | extracellular solute-binding protein UspC |
| M. thermoresistible (build 8) | TH_2011 | - | 4e-09 | 22.92% (336) | substrate binding protein |
| M. ulcerans Agy99 | MUL_1246 | uspC | 1e-141 | 60.41% (437) | periplasmic sugar-binding lipoprotein UspC |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2345|M.bovis_AF2122/97 -------MTRPRQSTLVATALVLVAILLGVTAVLLGLSA-----------
Rv2318|M.tuberculosis_H37Rv -------MTRPRQSTLVATALVLVAILLGVTAVLLGLSA-----------
MMAR_3619|M.marinum_M -------MSRPRFSTLVAVAVTLIAALLGVTAVALDRID-----------
MUL_1246|M.ulcerans_Agy99 -------MNRPRFSTLVAVAVTLIAALLGVTAVALDRID-----------
MAV_2088|M.avium_104 -------MTRPRFSTLVAGAVALVAALLAAAAVLLDYSG-----------
MLBr_01770|M.leprae_Br4923 -------MTRPRYSTLVAEALALATVLLTATAMLMGWSGG----------
MSMEG_4468|M.smegmatis_MC2_155 -------MRR---STLLAGGLAVTMAVLLVIAMLMGRTT-----------
MAB_1715c|M.abscessus_ATCC_199 ----------MKASTRAALTLALVALLLFGVAAWLGIPT-----------
Mflv_3775|M.gilvum_PYR-GCK MRFAQIPTARRGGKTARSAVLALLAVLALVLSACAGSGGPEQAESTGSGE
TH_2011|M.thermoresistible__bu -----------VRRTPIRAVLAAVAAVCLTLTGCAGAGT-----------
* :. : : .
Mb2345|M.bovis_AF2122/97 EPRGGKIVVTVRLWDEPIAAAYRQSFAAFTRSHPDIEVRTNLVAYSTYFE
Rv2318|M.tuberculosis_H37Rv EPRGGKIVVTVRLWDEPIAAAYRQSFAAFTRSHPDIEVRTNLVAYSTYFE
MMAR_3619|M.marinum_M APPGGKIVVTVRLWAAPIAAAYQQSFAAFSRTHPNIEVHTNLVSFSTYFD
MUL_1246|M.ulcerans_Agy99 APPGGKIVVTVRLWAAPIAAAYQQSFAAFSRTHPNIEVHTNLVSFSTYFD
MAV_2088|M.avium_104 QPHGDKTIVTVRVWGDELAEAYRQSFAAFTRAHPDIEVHVNMVAYSTYFN
MLBr_01770|M.leprae_Br4923 QLRGGKVVVTMRLWADQISTAYSQSFQAFTRTHPDIEVHTNVVAYSKYFN
MSMEG_4468|M.smegmatis_MC2_155 -EPAGKTVVTVRLWDPQVAAAYRESFDAFSAEHPGIEVRVNTVAYASYFD
MAB_1715c|M.abscessus_ATCC_199 -TPHGKTVVTVRVWDQQVAEAYRGSFDEFSRRNPDIQVAVTVTSYASYFN
Mflv_3775|M.gilvum_PYR-GCK VSADTSGTVRILMENVPDTDIVKSMVADFNAEYPGVEINIESLTFDQMRD
TH_2011|M.thermoresistible__bu -LGSSGNTVTIALVSNSQMSDAQRLAPHFEAANPDIRLKFVTLSENQARA
* : : * *.:.: :
Mb2345|M.bovis_AF2122/97 TLRTDVAGGS-ADDIFWLSNAYFAAYADSGRLMKIQT--------DAADW
Rv2318|M.tuberculosis_H37Rv TLRTDVAGGS-ADDIFWLSNAYFAAYADSGRLMKIQT--------DAADW
MMAR_3619|M.marinum_M TLRTDVAGGS-ADDIFWLSNAYLAAYADSGRLMKIDTAV------DPGEW
MUL_1246|M.ulcerans_Agy99 TLRTDVAGGS-ADDIFWLSNAYLAAYADSGRLMKIDTAV------DPGEW
MAV_2088|M.avium_104 TLRTDVAGGS-ADDIFWLSNAYLAAYADSGRLLNILDTLGTN---AAADW
MLBr_01770|M.leprae_Br4923 TLRTDVAGGS-ADDIFWLSSAYLAAYADNGRLINISNSLGQR---ATSDW
MSMEG_4468|M.smegmatis_MC2_155 SLRTDVAGGS-ADDIFWISNGYFAGYADNGHLLDIADLLGPD---AATAW
MAB_1715c|M.abscessus_ATCC_199 SLRTDVAGHG-ADDIFWLSNAYLSDYADTGNLVPVEP---------RADW
Mflv_3775|M.gilvum_PYR-GCK KLVSSFQSSSPAYDLIVVDNPWMVDFANAKFLQPLDARIDSTPDYDAGDF
TH_2011|M.thermoresistible__bu KITASTAMGGGEFDVVMISNYETPQWAADGWLVNLSDYARQTPGYDEDDF
.: :. . *:. :.. :* * : :
Mb2345|M.bovis_AF2122/97 EPAVVDQFTRSGVLWGVPQLTDAGIAVFYNADLLAAAGVDPTQVDNLRWS
Rv2318|M.tuberculosis_H37Rv EPAVVDQFTRSGVLWGVPQLTDAGIAVFYNADLLAAAGVDPTQVDNLRWS
MMAR_3619|M.marinum_M EPAVVDQFTRNGVLWGVPQLTDAGIAVFYNADLLAAAGVDPAELDGLRWS
MUL_1246|M.ulcerans_Agy99 EPAVVDQFTRNGVLWGVPQLTDAGIAVFYNADLLAAAGVDPAELDGLRWS
MAV_2088|M.avium_104 ERPVVEQFTRHGQLWGVPQLTDAGIALYYNADLLGAAGIDPAQLNSLRWN
MLBr_01770|M.leprae_Br4923 EPAVVDQFTRAGALWGVPQLTDAGIAVFYNADLLTAAGIDPVQLNRMQWT
MSMEG_4468|M.smegmatis_MC2_155 EPSVVEQFTRNGALWGVPQLTDAGIAVYYNADLLEKAGVSPADLSTLRWS
MAB_1715c|M.abscessus_ATCC_199 DPSVVAQFTRDGKLWGVPQLSDAGIALYYNKNLLDAAQVDPAELAELRWD
Mflv_3775|M.gilvum_PYR-GCK FTPLTDITTVDGTRYGVPFYNYALGYLYNADDLAAANQQVPTTLDELVST
TH_2011|M.thermoresistible__bu IPSIRESLSYEGDMYAVPFYGES-SFLMYRKDLFEKSGIDMPHNPTWQQV
.: : * :.** : : :*
Mb2345|M.bovis_AF2122/97 RGDD-DTLRPMLARLTVDADGRTANTPGFDARRVRQWGYNAANDPQAIYL
Rv2318|M.tuberculosis_H37Rv RGDD-DTLRPMLARLTVDADGRTANTPGFDARRVRQWGYNAANDPQAIYL
MMAR_3619|M.marinum_M PGPD-DTLRALLARLTVDADGHVGGTPGFDPGRVRQWGYNAANDPQAIYL
MUL_1246|M.ulcerans_Agy99 PGPD-DTLRALLARLTVDADGHVGGTPGFDPGRVRQWGYNAANDPQAIYL
MAV_2088|M.avium_104 PAGG-DTLRPLLARLTVDADGNRGDTRGFDPGRVRQWGYNAANDPQGIYL
MLBr_01770|M.leprae_Br4923 SNDD-DTLRPLLTQLTLDTNGHVAKTPGFDSRRVRQWGYNAANDPQAIYL
MSMEG_4468|M.smegmatis_MC2_155 NGPD-DTLRPLLARLTVEESG-----------RTRQWGYNAANDLQGIYL
MAB_1715c|M.abscessus_ATCC_199 PDPEVDTLRPMLHRLTA----------------PGHWGYNAANDLQGIYL
Mflv_3775|M.gilvum_PYR-GCK SKALKSGDRAGIA-------------------MQPQRGYKIFEEWG----
TH_2011|M.thermoresistible__bu ADAAAALDTPDMAG-------------------ICLRGKPGWGEVLAPLD
. : * :
Mb2345|M.bovis_AF2122/97 NYIGSAGG-VFQRDGKFAFDNPGAIEAFRYLVGLINDDHVAPPASDTNDN
Rv2318|M.tuberculosis_H37Rv NYIGSAGG-VFQRDGKFAFDNPGAIEAFRYLVGLINDDHVAPPASDTNDN
MMAR_3619|M.marinum_M NYIGSAGG-VFMRDNEFAFDNPPAIDAFRYLVGLINNDHVAPPASDTNDN
MUL_1246|M.ulcerans_Agy99 NYIGSAGG-VFMRDNEFAFDNPPAIDAFRYLVGLINNDHVAPPASDTNDN
MAV_2088|M.avium_104 NYIGSAGG-VFQRGDEFAFDNPAAVSAFRYLVDLINRDHVAPPAADTNDN
MLBr_01770|M.leprae_Br4923 NYIGSAGG-VFQRGDEFAFDNPSAVEAFRYLVGLINNDHVAPPASETNNN
MSMEG_4468|M.smegmatis_MC2_155 NFIGSAGG-TFSEGDRFTFDNPQAVEAFEYLVRLINTDRVAPPASDTNDN
MAB_1715c|M.abscessus_ATCC_199 NYLGSAGA-VFQADDKFAFAKPRAEMAFTYLVDLINVDRVAPSAADTNDN
Mflv_3775|M.gilvum_PYR-GCK NWLFAAGGSIYDADGKITLNTPEAKRALEAYIDTYN---TAAPANSLSWG
TH_2011|M.thermoresistible__bu TVINTFGGRWYDMDWNAQLDSPEVEEAVSFYVNLVRDHGEPGPATS---G
. : : *. : . . : .* . *. : . . .* . .
Mb2345|M.bovis_AF2122/97 GDFSRNQFLAGKMALFQSGTYSLAPVARDALF----HWGVAMLPAGPAGR
Rv2318|M.tuberculosis_H37Rv GDFSRNQFLAGKMALFQSGTYSLAPVARDALF----HWGVAMLPAGPAGR
MMAR_3619|M.marinum_M GDFSRNQFLAGRMALFQSGTYSLAPVARDATF----RWGVAMLPIGPAGR
MUL_1246|M.ulcerans_Agy99 GDFSRNQFLAGRMALFQSGTYSLAPVARDATF----RWGVAMLPIGPAGR
MAV_2088|M.avium_104 GDFSRNQFLAGRMALFQSGTYNLAPVARDARF----RWGVAMMPAGPVGR
MLBr_01770|M.leprae_Br4923 GDFSRNQFLSGRMALFQSGTYNLALIAREARF----HWGIAMMPTGPQGR
MSMEG_4468|M.smegmatis_MC2_155 GDFSRNAFLAGRMALFQSGTYNLAAIADQAPF----PWGVAMLPIGPKGR
MAB_1715c|M.abscessus_ATCC_199 NDFSRNQFLQGRMALFQSGTYNLAQIQANATF----PWDVAMMPAGPQGR
Mflv_3775|M.gilvum_PYR-GCK MDEAQRSVSANQSASMINYNWQLPALNEPGSG----PAAGKIKLATIPGG
TH_2011|M.thermoresistible__bu FGECATQFAQGRAAMWYDATSAVSVLEDPAQSNVVGKVGYALAPTVVKAD
. . . .: * . . :. : . : .
Mb2345|M.bovis_AF2122/97 VSVTNGIAAAGNSASKHPDAVRQVLAWMGST----------------EGN
Rv2318|M.tuberculosis_H37Rv VSVTNGIAAAGNSASKHPDAVRQVLAWMGST----------------EGN
MMAR_3619|M.marinum_M VSVTNGIAAAGNSASQHPDAVRQVLAWMGSS----------------AGN
MUL_1246|M.ulcerans_Agy99 VSVTNGIAAAGNSASQHPDAVRQVLAWMGSS----------------AGN
MAV_2088|M.avium_104 VSVTNGIAAAGNAATKHPGAVRQVLAWMGSR----------------QGN
MLBr_01770|M.leprae_Br4923 VSVTNGIAVAGNSATKHPDAVRQVLAWMGSR----------------EGN
MSMEG_4468|M.smegmatis_MC2_155 VSVTNGIAAAGNAATRHPEAVREVLAWMGSR----------------RGN
MAB_1715c|M.abscessus_ATCC_199 VSVTNGIVAAANSSSPHPDAVHKVLAWMGST----------------DGN
Mflv_3775|M.gilvum_PYR-GCK KQVLGSWSWAIPANSATPDAAWAFVSWITAK----------------PND
TH_2011|M.thermoresistible__bu AGWLYTWALGIPASSDNKDSAWKFISWMTDKNYIRLVGEELGWARVPPGN
. : : :. .::*: .:
Mb2345|M.bovis_AF2122/97 SYVGRHGAAIPAVLSAQPVYFDYWSARGVDVTPFFAVLNGPRIAAPGGAG
Rv2318|M.tuberculosis_H37Rv SYLGRHGAAIPAVLSAQPVYFDYWSARGVDVTPFFAVLNGPRIAAPGGAG
MMAR_3619|M.marinum_M EYLGRDGVAIPAVRSAQPSYFAFWEAKGVNVEPFFAVLSGSRIPAPGGAG
MUL_1246|M.ulcerans_Agy99 EYLGRDGVAIPAVRSAQPSYFAFWEAKGVNVNPFFAVLSGSRIPAPGGAG
MAV_2088|M.avium_104 EYLGRYGAAIPAVTSAQPVYFGYWAARGVDVTPFFAVLNGPRIAAPGGAG
MLBr_01770|M.leprae_Br4923 AYLGRHGAAVPAVRSAQSVYFDYWAAKGIDVTPFFSVLDGPHIPAPGGAG
MSMEG_4468|M.smegmatis_MC2_155 EFVGRRGAAIPAVLAAQPVYHEYWASRGVDVSPFFRVLQGPRIAAPGGAG
MAB_1715c|M.abscessus_ATCC_199 SFLGRSGSAIPAVLSARAPYFQYWADKGVDVSPFFEVLRGQQIAAPGGQG
Mflv_3775|M.gilvum_PYR-GCK VVRTEKGGAAIRKSTLQNP-AVLQGQFGEEYYRTVEQLLADAAPLTQGPS
TH_2011|M.thermoresistible__bu RLSTYQIPEYQQASEAFGQVTLESLENADTQHPTVQPVPYTGVQFLAIPE
. . :
Mb2345|M.bovis_AF2122/97 FAAGQQALEPYFDEMFLGRGDVTTTLRQAQAAANAATQR-----
Rv2318|M.tuberculosis_H37Rv FAAGQQALEPYFDEMFLGRGDVTTTLRQAQAAANAATQR-----
MMAR_3619|M.marinum_M FAAGNDALKPYFDEMFLGRGQVATILREAQAAANAAARR-----
MUL_1246|M.ulcerans_Agy99 FAAGNDALKPYFDEMFLGRGQVATILREAQAAANAAARR-----
MAV_2088|M.avium_104 FAAGNDALRPYFDEMFSGRGDVATTLRRAQAAANAAAARR----
MLBr_01770|M.leprae_Br4923 FPAGDDALQSYFDEMFLGHGDVEKILCQAQAAANTAAHR-----
MSMEG_4468|M.smegmatis_MC2_155 FPAGFEALTPYFAEMFLGRRDVAGTLAEAQRAANAAASR-----
MAB_1715c|M.abscessus_ATCC_199 FGAGFAALKPYFAEMFLGRLDVREALQQAQRAANRALER-----
Mflv_3775|M.gilvum_PYR-GCK GEEMIQAVGTALNEAVAGEKSVDDALATAQAEAEKIQG------
TH_2011|M.thermoresistible__bu FQDLGTRVSQQISAAIAGQKSVKDALAQAQKYAQVVGKTYQEKP
: : . *. .* * ** *: