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LTNATAPRSVRDRLIDAAETCLRAKGIRATTVSEVAEAAGVSRGWLYRHFPDKVSLLGAAIVRLNDAYWS DAHAFLAAYDGLDEKIAAGIRYGRTAYDDPGALLMKLRLDEPEEFAACAGAGVQGLVPDLAAFWTRYLLA ARDTGEIHPNTDIAEAAEWVARVVISFATVPGEQLDASDTGAVLTHLRRYVMPGLRAEPAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4953 | - | - | 100% (201) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4333 | - | 1e-09 | 42.11% (76) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 7e-08 | 30.84% (107) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3277c | - | 3e-06 | 25.30% (166) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2304 | - | 1e-70 | 64.77% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3249c | - | 3e-06 | 25.30% (166) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01733 | - | 4e-07 | 27.71% (166) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2606c | - | 3e-66 | 61.78% (191) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3161 | - | 2e-18 | 29.69% (192) | transcriptional regulatory protein |
| M. avium 104 | MAV_1333 | - | 8e-18 | 26.34% (205) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3720 | - | 6e-21 | 29.90% (194) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0934 | - | 3e-17 | 26.56% (192) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4342 | - | 3e-71 | 64.77% (193) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3277c|M.bovis_AF2122/97 -----------------------------MSTPSATVAPVKRIPYAEASR
Rv3249c|M.tuberculosis_H37Rv -----------------------------MSTPSATVAPVKRIPYAEASR
Mflv_2304|M.gilvum_PYR-GCK --------------------------------MSMSVGAFANSAPADQVT
Mvan_4342|M.vanbaalenii_PYR-1 --------------------------------MSMSVGTVPNSAGSNSAA
MSMEG_4953|M.smegmatis_MC2_155 ----------------------------------MTNATAP---------
MAB_2606c|M.abscessus_ATCC_199 ------------------------------MTAVFDEGSAPESDG-----
MAV_1333|M.avium_104 --------------------------------MSTDVSPAT---------
MUL_0934|M.ulcerans_Agy99 ----------------------MPPPDELVMPQSAALPQAT---------
TH_3720|M.thermoresistible__bu ----------------------------------VTEATAL---------
MMAR_3161|M.marinum_M ------------------------------MRWGAAAPSDR---------
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
Mb3277c|M.bovis_AF2122/97 ------------ALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQT
Rv3249c|M.tuberculosis_H37Rv ------------ALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQT
Mflv_2304|M.gilvum_PYR-GCK SPVADPPVEPKARTVRDRLIDAAEQCLTAKGIRATTVSEVAEVAGVSRGW
Mvan_4342|M.vanbaalenii_PYR-1 SARAEP------GSVRDRLIDAAEQCLTAKGIRATTVSEVAEVAGVSRGW
MSMEG_4953|M.smegmatis_MC2_155 ------------RSVRDRLIDAAETCLRAKGIRATTVSEVAEAAGVSRGW
MAB_2606c|M.abscessus_ATCC_199 ------------DSVTTRLLDATEKLLADKGIRATTMTDVAEEAGVSRSW
MAV_1333|M.avium_104 -------------DTRELIVAAAFTCFGRQGLQKATIVDIAKQAGVSRST
MUL_0934|M.ulcerans_Agy99 -------------DTRELIIGSAYVCFRRQGFQKTTIVDIARLANVSRST
TH_3720|M.thermoresistible__bu -------------ETREAIIMGAFACFRTYGLRKTTIVDIARKAEVSRST
MMAR_3161|M.marinum_M ------------DSARDRLLDAAERCLESCGVVGTTMEDIGRTAGVSRAT
MLBr_01733|M.leprae_Br4923 ERWREHR-----KKVRGEIVDAAFRALDRLGP-EVSVREIAEEAGTAKPK
:: . : . :: ::.. * ::
Mb3277c|M.bovis_AF2122/97 IYNEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFF
Rv3249c|M.tuberculosis_H37Rv IYNEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFF
Mflv_2304|M.gilvum_PYR-GCK LYRHFPDKSELLGAAIVRLNDAFWTESRTRLDS-VTGLDEQIAAGVALAR
Mvan_4342|M.vanbaalenii_PYR-1 LYRHFPDKAELLGAAIVRLNDAFWSESRTRLDA-VAGLDQQIAVGVELAR
MSMEG_4953|M.smegmatis_MC2_155 LYRHFPDKVSLLGAAIVRLNDAYWSDAHAFLAA-YDGLDEKIAAGIRYGR
MAB_2606c|M.abscessus_ATCC_199 LYRHFPDKPTLVGAAIIRLIEVSWAQSAAELAD-IDGFEARLVAGVKIGR
MAV_1333|M.avium_104 IYEYFSDKAAIVEACAEHASERFYREMAKAMDR-GGTLEERLCAAAVFVT
MUL_0934|M.ulcerans_Agy99 IYEYFRDKAAIMEGCAERASEQFYREMSKAMDR-GGSLQEKLCQAAVFVT
TH_3720|M.thermoresistible__bu VYEYFPDKAAIVEACAEAASERFYRNMAKVVNR-GEDLEDKLVRACVFVT
MMAR_3161|M.marinum_M VYRYFPNREAVMSGVIIRAAERYLDRINPRIAE-HTDLGSALVDFVEYTV
MLBr_01733|M.leprae_Br4923 IYRHFTDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYV
:*. * .: : . : : :
Mb3277c|M.bovis_AF2122/97 AESAADPLVISLLTG---VAKPDLLQLITTDSAPIITRASARLAP---AF
Rv3249c|M.tuberculosis_H37Rv AESAADPLVISLLTG---VAKPDLLQLITTDSAPIITRASARLAP---AF
Mflv_2304|M.gilvum_PYR-GCK KESETPGALVLKLRQ---EEPEAFTACVGLGVRGLIPEIAAFWEPYIQAA
Mvan_4342|M.vanbaalenii_PYR-1 KESETPGALVLKLRQ---EEPEAFTACVGLGVRGLIPEIAAFWVPYIQAA
MSMEG_4953|M.smegmatis_MC2_155 TAYDDPGALLMKLRL---DEPEEFAACAGAGVQGLVPDLAAFWTRYLLAA
MAB_2606c|M.abscessus_ATCC_199 RAYDDPGTLLMRIRL---REPEEFMACAGTGVQGLVPDLAGFWRPYLEAA
MAV_1333|M.avium_104 QARR----VIASEKY---FDEDAISLLLTKDAAVLLRECVEFFAPYLAAA
MUL_0934|M.ulcerans_Agy99 QSRQ----TIASAKY---FDQDAISLLLTKDSAVLLRECIDFFAPYLAAA
TH_3720|M.thermoresistible__bu QARR----VVQGEKY---FDEEEVSILLTRDSAVLLKECADFIAPYLSAG
MMAR_3161|M.marinum_M EAARREEIIGLLFGS---DEELAGVGLAAGTSTSLFELVTEFLRPIFRRH
MLBr_01733|M.leprae_Br4923 SLVDKHPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREM
:
Mb3277c|M.bovis_AF2122/97 TDTWVATTDNDANVLSRAIVRLCLSYVSMP-PEADHDVAADLARLITPFA
Rv3249c|M.tuberculosis_H37Rv TDTWVATTDNDANVLSRAIVRLCLSYVSMP-PEADHDVAADLARLITPFA
Mflv_2304|M.gilvum_PYR-GCK VDRGEIHADTDRAEAAEWIARITMSLATVPGEQCDVDDHESVLRHARRYI
Mvan_4342|M.vanbaalenii_PYR-1 VDRGEIHPDTNSAEAAEWIARIMMSLATVPGEQCNVDDHDSVLRHARRYI
MSMEG_4953|M.smegmatis_MC2_155 RDTGEIHPNTDIAEAAEWVARVVISFATVPGEQLDASDTGAVLTHLRRYV
MAB_2606c|M.abscessus_ATCC_199 RDTGEIHALTDIEEASEWIARVMISLGSVPGNRIDPDDPASLRRHFRRYV
MAV_1333|M.avium_104 RLTGEVRKDLDVEAAGEWFARILFSLFSTPSPTLNLDDPDVTAEFVRAHV
MUL_0934|M.ulcerans_Agy99 KLTGEVRKDLDVQAAAEWFARILFSLFSTPSPIRDMDDAQAVTEFVRAHV
TH_3720|M.thermoresistible__bu RVTGEVRKDLDIPKASEWVARILFSLFNTPSPTIDMSDDGAVADFVRSFV
MMAR_3161|M.marinum_M WS--YVEPGVSVDDAAEWVLRTILSLLTVRGPRERSRD--GLRTFLSRFL
MLBr_01733|M.leprae_Br4923 ELNRAASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMM
.
Mb3277c|M.bovis_AF2122/97 ERHGVIN--VP--------------------
Rv3249c|M.tuberculosis_H37Rv ERHGVIN--VP--------------------
Mflv_2304|M.gilvum_PYR-GCK VAAFRSD---PAGT-----------------
Mvan_4342|M.vanbaalenii_PYR-1 VAALRSD---PNQ------------------
MSMEG_4953|M.smegmatis_MC2_155 MPGLRAE---PAS------------------
MAB_2606c|M.abscessus_ATCC_199 LPALRIA---PVK------------------
MAV_1333|M.avium_104 VRGFASE--RPRRR-----------------
MUL_0934|M.ulcerans_Agy99 VDGFSDSRWRPARGVSKVH------------
TH_3720|M.thermoresistible__bu LRGFVDD--RPHRGRRSSAG-----------
MMAR_3161|M.marinum_M LPAILASDHCRPM------------------
MLBr_01733|M.leprae_Br4923 AVIVGTAETLGISMNPDRPIHDAVPLDRSAS