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STDVSPATDTRELIVAAAFTCFGRQGLQKATIVDIAKQAGVSRSTIYEYFSDKAAIVEACAEHASERFYR EMAKAMDRGGTLEERLCAAAVFVTQARRVIASEKYFDEDAISLLLTKDAAVLLRECVEFFAPYLAAARLT GEVRKDLDVEAAGEWFARILFSLFSTPSPTLNLDDPDVTAEFVRAHVVRGFASERPRRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1333 | - | - | 100% (200) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2157 | - | 1e-13 | 28.89% (180) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2883 | - | 3e-13 | 28.26% (184) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0237 | - | 3e-08 | 26.20% (187) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2304 | - | 1e-19 | 26.56% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0232 | - | 3e-08 | 26.20% (187) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 1e-06 | 36.07% (61) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0098 | - | 9e-19 | 30.21% (192) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4251 | - | 2e-81 | 74.62% (197) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4953 | - | 1e-17 | 26.34% (205) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3720 | - | 1e-70 | 65.10% (192) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0934 | - | 3e-81 | 74.11% (197) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4342 | - | 1e-19 | 28.27% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0237|M.bovis_AF2122/97 ----------MPTVTWAR------------------VDPARRAAVVEAAE
Rv0232|M.tuberculosis_H37Rv ----------MPTVTWAR------------------VDPARRAAVVEAAE
MMAR_4251|M.marinum_M --------MPQSAALPQ--------------------ATDTRELIIGSAY
MUL_0934|M.ulcerans_Agy99 MPPPDELVMPQSAALPQ--------------------ATDTRELIIGSAY
MAV_1333|M.avium_104 ----------MSTDVSP--------------------ATDTRELIVAAAF
TH_3720|M.thermoresistible__bu ------------VTEAT--------------------ALETREAIIMGAF
Mflv_2304|M.gilvum_PYR-GCK --------MSMSVGAFANSAPADQVTSPVADPPVEPKARTVRDRLIDAAE
Mvan_4342|M.vanbaalenii_PYR-1 --------MSMSVGTVPNSAGSNSAASARAEP------GSVRDRLIDAAE
MSMEG_4953|M.smegmatis_MC2_155 ----------MTNATAP---------------------RSVRDRLIDAAE
MAB_0098|M.abscessus_ATCC_1997 --------MKLVKTTGPR--------------------GEVPEPIVAAVA
MLBr_00717|M.leprae_Br4923 ----------MTTARRRLS------------------PEDRRAELLALGA
::
Mb0237|M.bovis_AF2122/97 AEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIASQRVR
Rv0232|M.tuberculosis_H37Rv AEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIASQRVR
MMAR_4251|M.marinum_M VCFRRQGFQKTTIVDIARLANVSRSTIYEYFRDKAAIMEGCAERASEQFY
MUL_0934|M.ulcerans_Agy99 VCFRRQGFQKTTIVDIARLANVSRSTIYEYFRDKAAIMEGCAERASEQFY
MAV_1333|M.avium_104 TCFGRQGLQKATIVDIAKQAGVSRSTIYEYFSDKAAIVEACAEHASERFY
TH_3720|M.thermoresistible__bu ACFRTYGLRKTTIVDIARKAEVSRSTVYEYFPDKAAIVEACAEAASERFY
Mflv_2304|M.gilvum_PYR-GCK QCLTAKGIRATTVSEVAEVAGVSRGWLYRHFPDKSELLGAAIVRLNDAFW
Mvan_4342|M.vanbaalenii_PYR-1 QCLTAKGIRATTVSEVAEVAGVSRGWLYRHFPDKAELLGAAIVRLNDAFW
MSMEG_4953|M.smegmatis_MC2_155 TCLRAKGIRATTVSEVAEAAGVSRGWLYRHFPDKVSLLGAAIVRLNDAYW
MAB_0098|M.abscessus_ATCC_1997 QTLVRSGIQRFSLSAAADEAGVSRGTIYNWFGGKKEAIDVAVGFIAGAFI
MLBr_00717|M.leprae_Br4923 EVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLY
: : * * *::. ::. * .*
Mb0237|M.bovis_AF2122/97 SYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRE--RALHAAA-TLE
Rv0232|M.tuberculosis_H37Rv SYMEDLIRELDPNRPFFEFLTDLLDGWVAYFAEHPRE--RALHAAA-TLE
MMAR_4251|M.marinum_M REMSKAMDRGGS-------LQEKLCQAAVFVTQSRQ----AIASAK-YFD
MUL_0934|M.ulcerans_Agy99 REMSKAMDRGGS-------LQEKLCQAAVFVTQSRQ----TIASAK-YFD
MAV_1333|M.avium_104 REMAKAMDRGGT-------LEERLCAAAVFVTQARR----VIASEK-YFD
TH_3720|M.thermoresistible__bu RNMAKVVNRGED-------LEDKLVRACVFVTQARR----VVQGEK-YFD
Mflv_2304|M.gilvum_PYR-GCK TESRTRLDSVTG-------LDEQIAAGVALARKESETPGALVLKLR-QEE
Mvan_4342|M.vanbaalenii_PYR-1 SESRTRLDAVAG-------LDQQIAVGVELARKESETPGALVLKLR-QEE
MSMEG_4953|M.smegmatis_MC2_155 SDAHAFLAAYDG-------LDEKIAAGIRYGRTAYDDPGALLMKLR-LDE
MAB_0098|M.abscessus_ATCC_1997 ELFAGAVSAKTT-------LTDQVGEAAVRISDHRAWS--DRLDPT-LHV
MLBr_00717|M.leprae_Br4923 AATNIPPPAGLT------MFEEVRVGVLAYMAYHKQNPEAAWAAYVGLGR
: :
Mb0237|M.bovis_AF2122/97 VDTDARISVR--SVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLL
Rv0232|M.tuberculosis_H37Rv VDTDARISVR--SVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLL
MMAR_4251|M.marinum_M EDAISLLLTKDSAVLLRECIDFFAPYLAAAKLTGEVRKDLDVQAAAEWFA
MUL_0934|M.ulcerans_Agy99 QDAISLLLTKDSAVLLRECIDFFAPYLAAAKLTGEVRKDLDVQAAAEWFA
MAV_1333|M.avium_104 EDAISLLLTKDAAVLLRECVEFFAPYLAAARLTGEVRKDLDVEAAGEWFA
TH_3720|M.thermoresistible__bu EEEVSILLTRDSAVLLKECADFIAPYLSAGRVTGEVRKDLDIPKASEWVA
Mflv_2304|M.gilvum_PYR-GCK PEAFTACVGLGVRGLIPEIAAFWEPYIQAAVDRGEIHADTDRAEAAEWIA
Mvan_4342|M.vanbaalenii_PYR-1 PEAFTACVGLGVRGLIPEIAAFWVPYIQAAVDRGEIHPDTNSAEAAEWIA
MSMEG_4953|M.smegmatis_MC2_155 PEEFAACAGAGVQGLVPDLAAFWTRYLLAARDTGEIHPNTDIAEAAEWVA
MAB_0098|M.abscessus_ATCC_1997 SNVLELVLEECGDDLMRRSVEFWVPQVEAAKHRGEIGGDVDATEAAEWIM
MLBr_00717|M.leprae_Br4923 SDPVLLGIDDEAKNRQMEHIMSRIGDVVSVVPESKLHPDIERDLRVIVHG
: : ..: : :
Mb0237|M.bovis_AF2122/97 LIFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPA
Rv0232|M.tuberculosis_H37Rv LIFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPA
MMAR_4251|M.marinum_M RILFSLFSTP-----SPIRDMDD---AQAVTEFVRAHVVDGFSDSRWRPA
MUL_0934|M.ulcerans_Agy99 RILFSLFSTP-----SPIRDMDD---AQAVTEFVRAHVVDGFSDSRWRPA
MAV_1333|M.avium_104 RILFSLFSTP-----SPTLNLDD---PDVTAEFVRAHVVRGFASE--RPR
TH_3720|M.thermoresistible__bu RILFSLFNTP-----SPTIDMSD---DGAVADFVRSFVLRGFVDD--RPH
Mflv_2304|M.gilvum_PYR-GCK RITMSLATVP-----GEQCDVDD---HESVLRHARRYIVAAFRSD---PA
Mvan_4342|M.vanbaalenii_PYR-1 RIMMSLATVP-----GEQCNVDD---HDSVLRHARRYIVAALRSD---PN
MSMEG_4953|M.smegmatis_MC2_155 RVVISFATVP-----GEQLDASD---TGAVLTHLRRYVMPGLRAE---PA
MAB_0098|M.abscessus_ATCC_1997 RTLMSIEVLP-----AISVDLTD---PNRVRRYFSRFILRGLA-------
MLBr_00717|M.leprae_Br4923 WLAFTFEVCR-QRIMDPSTDADRLADSCAHALLDAIARVPEISKELADAM
: . :
Mb0237|M.bovis_AF2122/97 TNSAQTRSEEIT
Rv0232|M.tuberculosis_H37Rv TNSAQTRSEEIT
MMAR_4251|M.marinum_M RGVSKVH-----
MUL_0934|M.ulcerans_Agy99 RGVSKVH-----
MAV_1333|M.avium_104 RR----------
TH_3720|M.thermoresistible__bu RGRRSSAG----
Mflv_2304|M.gilvum_PYR-GCK GT----------
Mvan_4342|M.vanbaalenii_PYR-1 Q-----------
MSMEG_4953|M.smegmatis_MC2_155 S-----------
MAB_0098|M.abscessus_ATCC_1997 ------------
MLBr_00717|M.leprae_Br4923 AIARQPPQ----