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VSISNDDAGESLGERILEAAASCVMAFGVDRVTLAEIARRAGVSRPTVYRRFPDTRSILAALLTARIVRV LDEVESDARGREALVRRIVAVAERLRHDEVIMAVLHTAPDVAMVYIAERLGTSQQILIDAVAGEIKIAQE GGSVRAGDARQLATMCLLITQSAIQSAQMVAPILDADALARELAYSLNGYLKP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4333 | - | - | 100% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4953 | - | 9e-10 | 42.11% (76) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3425 | - | 4e-08 | 28.81% (177) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2274c | - | 2e-61 | 65.10% (192) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2773 | - | 3e-58 | 59.79% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2250c | - | 2e-61 | 65.10% (192) | transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 2e-05 | 40.68% (59) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3883c | - | 3e-40 | 47.59% (187) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3343 | - | 6e-60 | 61.46% (192) | transcriptional regulatory protein |
| M. avium 104 | MAV_2187 | - | 2e-61 | 64.95% (194) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1508 | - | 3e-59 | 64.44% (180) | Possible transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_1299 | - | 9e-60 | 61.46% (192) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3760 | - | 2e-61 | 61.34% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2773|M.gilvum_PYR-GCK -MMSIRNSE---------------PVEQRILDAAAECIRAYGVERTTVTE
Mvan_3760|M.vanbaalenii_PYR-1 -MVSIRNPER--------------SVEQRILDAAAACILAYGVERTTMTE
Mb2274c|M.bovis_AF2122/97 -MLSMSNDR--------------ADTGGRILRAAASCVVDYGVDRVTLAE
Rv2250c|M.tuberculosis_H37Rv -MLSMSNDR--------------ADTGGRILRAAASCVVDYGVDRVTLAE
MMAR_3343|M.marinum_M -MLSMSNAP--------------EDIGDRILQAAASCVRDYGVDRVTLAE
MUL_1299|M.ulcerans_Agy99 -MLSMSNAP--------------EDIGDRILQAAASCVRDYGVDRVTLAE
MAV_2187|M.avium_104 -MLSIRNDRP----------DAALDTGERILAAAASCVVDFGVDRVTLAE
MSMEG_4333|M.smegmatis_MC2_155 -MVSISNDDA----------G--ESLGERILEAAASCVMAFGVDRVTLAE
TH_1508|M.thermoresistible__bu -------------------------VEDRILDAAAASVLAVGVNRVTLTD
MAB_3883c|M.abscessus_ATCC_199 -MAPLVDAGGGVTVQAMDAQASADPVTERILDAALSCVTEFGVRRTTLVE
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-VPIDE
*** .* .. *: ..: :
Mflv_2773|M.gilvum_PYR-GCK IARRAGVSRPTIYRRWPDIRWVIAEVLTVRISDVLA----AVPAAGPGRE
Mvan_3760|M.vanbaalenii_PYR-1 IARRARVSRPTIYRRWPDIRWVIAELLTVRITGVLE----AVPDRGAGRE
Mb2274c|M.bovis_AF2122/97 IARRAGVSRPTVYRRWPDTRSIMASMLTSHIAAVLR----EVPLDGDDRE
Rv2250c|M.tuberculosis_H37Rv IARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLR----EVPLDGDDRE
MMAR_3343|M.marinum_M IARRAGVSRPTVYRRWPDTRSIISALLTSHVTDVVR----AVSLDGHDRQ
MUL_1299|M.ulcerans_Agy99 IARRAGVSRPTVYRRWPDTRSIISALLTSHVTDVVR----AVFLDGHDRQ
MAV_2187|M.avium_104 IARRAGVSRPTVYRRWPDTRSIVAALLTRHVTDVMR----AAPLLGDDRE
MSMEG_4333|M.smegmatis_MC2_155 IARRAGVSRPTVYRRFPDTRSILAALLTARIVRVLD----EVESDARGRE
TH_1508|M.thermoresistible__bu IARRARVSRPTIYRRWPDTNALLASLLTTRITAVLD----EVPTRGNDRE
MAB_3883c|M.abscessus_ATCC_199 VAKRAGVSRPSVYRRWPDVRTLVAELLTREMGSILP----ATG-RGCARE
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGPGEA
:*:** *. ::**::* . : : :: .: :: . .
Mflv_2773|M.gilvum_PYR-GCK ELVDRVVRIAEHLRRDDIVMSVIFNAPTLAMVYITERLGTSQQLLIDTLA
Mvan_3760|M.vanbaalenii_PYR-1 SVVGRVVAVADHLRADEIVQSVIRNAPGLAMTYITDRLGTSQQILIDALA
Mb2274c|M.bovis_AF2122/97 ALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLA
Rv2250c|M.tuberculosis_H37Rv ALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLA
MMAR_3343|M.marinum_M TVVRQVVAVADRLRGDELVKALMHS--DLARVYITERLGASQHFLLEGLA
MUL_1299|M.ulcerans_Agy99 TVVRQVVAVADRLRGDELVKALMHS--DLARVYITERLGASQHFLLEGLA
MAV_2187|M.avium_104 SLVRQIVTVADLLRQDRLVMSVLHS--ELAPIYITERLGTSQHMLIDALA
MSMEG_4333|M.smegmatis_MC2_155 ALVRRIVAVAERLRHDEVIMAVLHTAPDVAMVYIAERLGTSQQILIDAVA
TH_1508|M.thermoresistible__bu SLVERIVGFAERLRADEVVMSVLYGAPEFTMVYITDRLGSSQRIMIEALA
MAB_3883c|M.abscessus_ATCC_199 RLVRSVTGLVTQVREHSIFAAILRSDPELLLTYIVQRLGTSQRALIGWTA
MLBr_00316|M.leprae_Br4923 LFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAP---DAEDAFLTILS
.. . . . : . :. :: :: :
Mflv_2773|M.gilvum_PYR-GCK AAIVQGQAHGSVRAGDPHQMGAMCLLIAQSTIQSAQMVEKFLDRDALNAE
Mvan_3760|M.vanbaalenii_PYR-1 EAIKAGQDEGSIRAGDPRGMAAMCLLITQSTIQSAQMVAELLDNEALNEE
Mb2274c|M.bovis_AF2122/97 ARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATE
Rv2250c|M.tuberculosis_H37Rv ARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATE
MMAR_3343|M.marinum_M ARLQVAQGTGSVRAGDPRKLAAMVLLITQSTIQSVDIIDPILDSEALAAE
MUL_1299|M.ulcerans_Agy99 ARLQVAQGTGSVRAGDPRKLAAMVLLITQSTIQSVDIIDPILDSEALAAE
MAV_2187|M.avium_104 ARLRVAQRNGSVRPGDPVQMATMVLLIAQSTIQSAQIVEPLLDAEALATE
MSMEG_4333|M.smegmatis_MC2_155 GEIKIAQEGGSVRAGDARQLATMCLLITQSAIQSAQMVAPILDADALARE
TH_1508|M.thermoresistible__bu REIAEAQETGTVRAGDPHQLAAMCGLIAQSAVQSARIVEPFLDSEALAAE
MAB_3883c|M.abscessus_ATCC_199 MLIVEGQADGSIRAGIPEQMAAMVLLIGQSVLQSARIVADILSPDELVDE
MLBr_00316|M.leprae_Br4923 DLLYAAQYAGTART-DVGVREVKSILVGCQAMEAYNSALAERVTDVVVDG
: .* *: *. . *: ..::: :
Mflv_2773|M.gilvum_PYR-GCK LAHSLNGYLKP
Mvan_3760|M.vanbaalenii_PYR-1 LAHSLNGYLKP
Mb2274c|M.bovis_AF2122/97 LTHALNGYLC-
Rv2250c|M.tuberculosis_H37Rv LTHALNGYLC-
MMAR_3343|M.marinum_M LTYSLNGYLA-
MUL_1299|M.ulcerans_Agy99 LTYSLNGYLA-
MAV_2187|M.avium_104 LAYSLNGYLS-
MSMEG_4333|M.smegmatis_MC2_155 LAYSLNGYLKP
TH_1508|M.thermoresistible__bu LRRSLNGYLKP
MAB_3883c|M.abscessus_ATCC_199 LATAIDGYLKA
MLBr_00316|M.leprae_Br4923 LRAAR------
* :