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SMSVGAFANSAPADQVTSPVADPPVEPKARTVRDRLIDAAEQCLTAKGIRATTVSEVAEVAGVSRGWLYR HFPDKSELLGAAIVRLNDAFWTESRTRLDSVTGLDEQIAAGVALARKESETPGALVLKLRQEEPEAFTAC VGLGVRGLIPEIAAFWEPYIQAAVDRGEIHADTDRAEAAEWIARITMSLATVPGEQCDVDDHESVLRHAR RYIVAAFRSDPAGT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2304 | - | - | 100% (225) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3024 | - | 3e-17 | 33.33% (189) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4624 | - | 3e-16 | 32.28% (189) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3076c | - | 2e-08 | 36.56% (93) | AsnC family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3050c | - | 3e-08 | 36.56% (93) | AsnC family transcriptional regulator |
| M. leprae Br4923 | MLBr_01733 | - | 2e-08 | 36.71% (79) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2606c | - | 1e-57 | 52.04% (196) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4251 | - | 1e-20 | 27.75% (191) | transcriptional regulator |
| M. avium 104 | MAV_1333 | - | 1e-19 | 26.56% (192) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4953 | - | 2e-70 | 64.77% (193) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_4573 | - | 2e-18 | 31.09% (193) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0934 | - | 9e-22 | 27.67% (206) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4342 | - | 1e-102 | 84.23% (222) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2304|M.gilvum_PYR-GCK -------------------------------------MSMSVGAFANSAP
Mvan_4342|M.vanbaalenii_PYR-1 -------------------------------------MSMSVGTVPNSAG
MSMEG_4953|M.smegmatis_MC2_155 ---------------------------------------MTNATAP----
MAB_2606c|M.abscessus_ATCC_199 -----------------------------------MTAVFDEGSAPESDG
MMAR_4251|M.marinum_M ---------------------------------------MPQSAALPQA-
MUL_0934|M.ulcerans_Agy99 -------------------------------MPPPDELVMPQSAALPQA-
MAV_1333|M.avium_104 -----------------------------------------MSTDVSPA-
TH_4573|M.thermoresistible__bu ----------------------------------MATQRATADVEEQHE-
Mb3076c|M.bovis_AF2122/97 -----------------------------MVRIPRPHPSAKPGVKVDARS
Rv3050c|M.tuberculosis_H37Rv -----------------------------MVRIPRPHPSAKPGVKVDARS
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
Mflv_2304|M.gilvum_PYR-GCK ADQVTSPVADPPVEPKARTVRDRLIDAAEQCLTAKGIRATTVSEVAEVAG
Mvan_4342|M.vanbaalenii_PYR-1 SNSAASARAEP------GSVRDRLIDAAEQCLTAKGIRATTVSEVAEVAG
MSMEG_4953|M.smegmatis_MC2_155 -----------------RSVRDRLIDAAETCLRAKGIRATTVSEVAEAAG
MAB_2606c|M.abscessus_ATCC_199 -----------------DSVTTRLLDATEKLLADKGIRATTMTDVAEEAG
MMAR_4251|M.marinum_M -----------------TDTRELIIGSAYVCFRRQGFQKTTIVDIARLAN
MUL_0934|M.ulcerans_Agy99 -----------------TDTRELIIGSAYVCFRRQGFQKTTIVDIARLAN
MAV_1333|M.avium_104 -----------------TDTRELIVAAAFTCFGRQGLQKATIVDIAKQAG
TH_4573|M.thermoresistible__bu -----------------SDRRDQILEAANACFAQLGIHRTSVQDVARAAN
Mb3076c|M.bovis_AF2122/97 ERWREHR----------KKVRNEIVDAAFRAIDRLGP-ELSVRQIAEEAG
Rv3050c|M.tuberculosis_H37Rv ERWREHR----------KKVRNEIVDAAFRAIDRLGP-ELSVRQIAEEAG
MLBr_01733|M.leprae_Br4923 ERWREHR----------KKVRGEIVDAAFRALDRLGP-EVSVREIAEEAG
:: :: : * :: ::*. *.
Mflv_2304|M.gilvum_PYR-GCK VSRGWLYRHFPDKSELLGAAIVRLNDAFWTESRTRLDSVTG-----LDEQ
Mvan_4342|M.vanbaalenii_PYR-1 VSRGWLYRHFPDKAELLGAAIVRLNDAFWSESRTRLDAVAG-----LDQQ
MSMEG_4953|M.smegmatis_MC2_155 VSRGWLYRHFPDKVSLLGAAIVRLNDAYWSDAHAFLAAYDG-----LDEK
MAB_2606c|M.abscessus_ATCC_199 VSRSWLYRHFPDKPTLVGAAIIRLIEVSWAQSAAELADIDG-----FEAR
MMAR_4251|M.marinum_M VSRSTIYEYFRDKAAIMEGCAERASEQFYREMSKAMDRGGS-----LQEK
MUL_0934|M.ulcerans_Agy99 VSRSTIYEYFRDKAAIMEGCAERASEQFYREMSKAMDRGGS-----LQEK
MAV_1333|M.avium_104 VSRSTIYEYFSDKAAIVEACAEHASERFYREMAKAMDRGGT-----LEER
TH_4573|M.thermoresistible__bu VSRGTVYRYFEDRTILIEAAIEYGAQKFYQEIAAAMAKKST-----LAEQ
Mb3076c|M.bovis_AF2122/97 TAKPKIYRHFTDKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRS
Rv3050c|M.tuberculosis_H37Rv TAKPKIYRHFTDKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRS
MLBr_01733|M.leprae_Br4923 TAKPKIYRHFTDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRS
.:: :*.:* *: :. . : : : :
Mflv_2304|M.gilvum_PYR-GCK IAAGVALARKESETPGALVLKLRQEEPEAFTACVGLGVRGLIPEIAAFW-
Mvan_4342|M.vanbaalenii_PYR-1 IAVGVELARKESETPGALVLKLRQEEPEAFTACVGLGVRGLIPEIAAFW-
MSMEG_4953|M.smegmatis_MC2_155 IAAGIRYGRTAYDDPGALLMKLRLDEPEEFAACAGAGVQGLVPDLAAFW-
MAB_2606c|M.abscessus_ATCC_199 LVAGVKIGRRAYDDPGTLLMRIRLREPEEFMACAGTGVQGLVPDLAGFW-
MMAR_4251|M.marinum_M LCQAAVFVTQSRQ--AIASAKYFDEDAISLL--LTKDSAVLLRECIDFF-
MUL_0934|M.ulcerans_Agy99 LCQAAVFVTQSRQ--TIASAKYFDQDAISLL--LTKDSAVLLRECIDFF-
MAV_1333|M.avium_104 LCAAAVFVTQARR--VIASEKYFDEDAISLL--LTKDAAVLLRECVEFF-
TH_4573|M.thermoresistible__bu LGAMAETHAKILL--DHRTRNRLMTDDAELMRHMIADADAAVRRTTEFL-
Mb3076c|M.bovis_AF2122/97 VEEYVNLVDQHPNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNN
Rv3050c|M.tuberculosis_H37Rv VEEYVNLVDQHPNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNN
MLBr_01733|M.leprae_Br4923 VDEYVSLVDKHPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNN
: : . : *
Mflv_2304|M.gilvum_PYR-GCK ----EPYIQAAVDRGEIHADTDRAEAAEWIAR-------------ITMSL
Mvan_4342|M.vanbaalenii_PYR-1 ----VPYIQAAVDRGEIHPDTNSAEAAEWIAR-------------IMMSL
MSMEG_4953|M.smegmatis_MC2_155 ----TRYLLAARDTGEIHPNTDIAEAAEWVAR-------------VVISF
MAB_2606c|M.abscessus_ATCC_199 ----RPYLEAARDTGEIHALTDIEEASEWIAR-------------VMISL
MMAR_4251|M.marinum_M ----APYLAAAKLTGEVRKDLDVQAAAEWFAR-------------ILFSL
MUL_0934|M.ulcerans_Agy99 ----APYLAAAKLTGEVRKDLDVQAAAEWFAR-------------ILFSL
MAV_1333|M.avium_104 ----APYLAAARLTGEVRKDLDVEAAGEWFAR-------------ILFSL
TH_4573|M.thermoresistible__bu ----MPYVQQAKERGEVGSGVDVKAASEWLAR-------------IIYSF
Mb3076c|M.bovis_AF2122/97 ELREMELNRAALELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHL
Rv3050c|M.tuberculosis_H37Rv ELREMELNRAALELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHL
MLBr_01733|M.leprae_Br4923 ELREMELNRAASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHL
* . . . * ** . :
Mflv_2304|M.gilvum_PYR-GCK ATVPG-EQCDVDDHESVLRHARRYIVAAFRSDPAGT--------
Mvan_4342|M.vanbaalenii_PYR-1 ATVPG-EQCNVDDHDSVLRHARRYIVAALRSDPNQ---------
MSMEG_4953|M.smegmatis_MC2_155 ATVPG-EQLDASDTGAVLTHLRRYVMPGLRAEPAS---------
MAB_2606c|M.abscessus_ATCC_199 GSVPG-NRIDPDDPASLRRHFRRYVLPALRIAPVK---------
MMAR_4251|M.marinum_M FSTPS-PIRDMDDAQAVTEFVRAHVVDGFSDSRWRPARGVSKVH
MUL_0934|M.ulcerans_Agy99 FSTPS-PIRDMDDAQAVTEFVRAHVVDGFSDSRWRPARGVSKVH
MAV_1333|M.avium_104 FSTPS-PTLNLDDPDVTAEFVRAHVVRGFASE--RPRRR-----
TH_4573|M.thermoresistible__bu TTVNEGLTFDMSKPATVRRYVERFAVNGLR--------------
Mb3076c|M.bovis_AF2122/97 TTIMMGVIVGTAEALGIAVDPDQPIHDAVPNNPAVR--------
Rv3050c|M.tuberculosis_H37Rv TTIMMGVIVGTAEALGIAVDPDQPIHDAVPNNPAVR--------
MLBr_01733|M.leprae_Br4923 TIIMMAVIVGTAETLGISMNPDRPIHDAVPLDRSAS--------
. . ..