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M. bovis AF2122 / 97 Mb3277c (-)

annotation: TetR family transcriptional regulator
coordinates: 3584352 - 3584987
length: 211

VSTPSATVAPVKRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGL
AQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPDLLQLITTDSAP
IITRASARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINV
P
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3277c--100% (211)TetR family transcriptional regulator
M. bovis AF2122 / 97Mb0310-1e-0626.50% (117) TetR/ACRR family transcriptional regulator
M. bovis AF2122 / 97Mb3081-6e-0644.26% (61) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4718-1e-8474.64% (209) TetR family transcriptional regulator
M. tuberculosis H37RvRv3249c-1e-115100.00% (211) TetR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3596c-1e-7065.13% (195) TetR family transcriptional regulator
M. marinum MMMAR_1294-1e-10392.16% (204) TetR family transcriptional regulator
M. avium 104MAV_4212-3e-9486.50% (200) putative transcriptional regulatory protein
M. smegmatis MC2 155MSMEG_1842-2e-8372.99% (211) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0467-4e-8478.68% (197) POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99MUL_2593-1e-10291.67% (204) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1745-2e-8475.76% (198) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb3277c|M.bovis_AF2122/97           -----------------------------------MSTPSAT----VAPV
Rv3249c|M.tuberculosis_H37Rv        -----------------------------------MSTPSAT----VAPV
MMAR_1294|M.marinum_M               ----------------------------------MIDTNSFAKRDIVGPV
MUL_2593|M.ulcerans_Agy99           ---------------MPRLRCGKGGLRDGGGGSTVIDTNSFAKRDIVGPV
MAV_4212|M.avium_104                -------------------------------------------------M
Mflv_4718|M.gilvum_PYR-GCK          -MTAQPIATSARVATRHADQRRADTRARGASLGPVRATVIVAPVGG-GND
Mvan_1745|M.vanbaalenii_PYR-1       -MRATHRAEPC----RHARSRNTASQGTAVTASAGPGTITVARVGL-SND
TH_0467|M.thermoresistible__bu      ---------------------------------------VVSRR-----D
MSMEG_1842|M.smegmatis_MC2_155      MIHAVTHAVAG---------AQFGAPARVVRGPLTAESDIVARVSRPRAK
MAB_3596c|M.abscessus_ATCC_199      -MTDVLP--------------GRDALTSASVPARLPGVTRPDALRAGGSS
                                                                                      

Mb3277c|M.bovis_AF2122/97           KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
Rv3249c|M.tuberculosis_H37Rv        KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
MMAR_1294|M.marinum_M               KRVPYAEASRVLLRDSVLDAMRDLLLTRDWSAITLSDVARSAGISRQTIY
MUL_2593|M.ulcerans_Agy99           KRVPYAEASRVLLRDSVLDAMRDLLFTRDWSAITLSDVARSAGISRQTIY
MAV_4212|M.avium_104                KRMPYAEASRALLRDSVLDAMRDLLVTRDWSAITLSDVARAAGISRQTIY
Mflv_4718|M.gilvum_PYR-GCK          KRISYAEASRVLLRDSILDGMREMLLARDWSQITLSDVAKAAGISRQTIY
Mvan_1745|M.vanbaalenii_PYR-1       KRVSYAEASRVLLRDSILDGMREMLLTRDWSAITLSDVAKAAGISRQTIY
TH_0467|M.thermoresistible__bu      KRVPYAEASRVLLRDSILDGMRELLQTRDWSQITLADVAKAAGISRQTIY
MSMEG_1842|M.smegmatis_MC2_155      QRMPYAEASRVLLRDSILDGMRDLLLTRDWSAITLSHVAQAAGVSRQTIY
MAB_3596c|M.abscessus_ATCC_199      HRVPYAEAARALLRESVLDALGDLLRQRDWSAVTMSDVSRRAGVSRQTLY
                                    :*:.****:*.***:*:**.: ::*  **** :*::.*:: **:****:*

Mb3277c|M.bovis_AF2122/97           NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
Rv3249c|M.tuberculosis_H37Rv        NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
MMAR_1294|M.marinum_M               NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
MUL_2593|M.ulcerans_Agy99           NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
MAV_4212|M.avium_104                NEFGSRQGLAQGYALRLADRLVDTIHEALDAHVGNIYESFLDAFRRFFAD
Mflv_4718|M.gilvum_PYR-GCK          NEFGSRQGLAQGYAMRLADRLVDQIHAAIDNNVGDMYAAFLQGFRDFFVE
Mvan_1745|M.vanbaalenii_PYR-1       NEFGSRQGLAQGYAMRLADRLVDQIHGAINGNAGDVYAAFLQGFRDFFVE
TH_0467|M.thermoresistible__bu      NEFGSRQGLAQGYALRLADRLVDEVDEAIANNVGDIHAAFLAGFRKFFAE
MSMEG_1842|M.smegmatis_MC2_155      NEFGSRQGLAEGYAMRLADRLVDAVDDAINNNVGDVYAAFLEGFRAFFAE
MAB_3596c|M.abscessus_ATCC_199      NEFGSRQGLAQGYALRLAHRLVDAVGDAIYAHVGDIHGALHSGFADFFAE
                                    **********:***:***.**** :  ::  :.*:.: ::  .*  ** :

Mb3277c|M.bovis_AF2122/97           SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
Rv3249c|M.tuberculosis_H37Rv        SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
MMAR_1294|M.marinum_M               SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATS
MUL_2593|M.ulcerans_Agy99           SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATS
MAV_4212|M.avium_104                AAADPLVTSLRTGVAKPDLLQLITTDSAVIITRASARLASALTHTWVSTT
Mflv_4718|M.gilvum_PYR-GCK          SAADPLVISLLTGSSKPDLLQLITTDSAPIINHCSSRLTESLMGSWVRCS
Mvan_1745|M.vanbaalenii_PYR-1       SAADPLVISLLTGTSKPDLLQLITTDSAPIINHCSSRLTESFMSSWVRVS
TH_0467|M.thermoresistible__bu      SAADPLVISLLTGSAKPDLLQLITTDSAPIITRASQRLTESFQSSWVRAS
MSMEG_1842|M.smegmatis_MC2_155      SAADPLVISLLTGAAKPDLLQIITIGSGPIITRCSERLTATFQSSWIKAS
MAB_3596c|M.abscessus_ATCC_199      SAADPMVISLLTGEAKPELMRIVTVDSALIVVPASARLTESFMNSWVAAS
                                    :****:* ** ** :**:*::::* .*. *:  .* **: ::  :*:  :

Mb3277c|M.bovis_AF2122/97           DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
Rv3249c|M.tuberculosis_H37Rv        DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
MMAR_1294|M.marinum_M               DDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP
MUL_2593|M.ulcerans_Agy99           DDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP
MAV_4212|M.avium_104                DEDAGVLARAIVRLALSYVSMPPEADHDVAADLARLMTPFAERHGVVNVG
Mflv_4718|M.gilvum_PYR-GCK          EEDAGVLSRAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVVADP
Mvan_1745|M.vanbaalenii_PYR-1       QEDAGVLARAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVIDP-
TH_0467|M.thermoresistible__bu      EEDAGVLARAIVRLAMSYVSMPPEADHDVAHDLARLMTPFAERYGVIEEV
MSMEG_1842|M.smegmatis_MC2_155      DDDAGVLARAIVRLAMSYVSMPPEADHDVAGDLARLMSPFAERYGVIDTP
MAB_3596c|M.abscessus_ATCC_199      QEDASILARSIVRLAISYVSMPPESDHDVALDMARLLSPFVETNALADKA
                                    ::**.:*:*:****.:**:*****:**:** *:***::**.*  .:    

Mb3277c|M.bovis_AF2122/97           ------------
Rv3249c|M.tuberculosis_H37Rv        ------------
MMAR_1294|M.marinum_M               ------------
MUL_2593|M.ulcerans_Agy99           ------------
MAV_4212|M.avium_104                ------------
Mflv_4718|M.gilvum_PYR-GCK          VEGGNSQVTRRP
Mvan_1745|M.vanbaalenii_PYR-1       ------------
TH_0467|M.thermoresistible__bu      ------------
MSMEG_1842|M.smegmatis_MC2_155      ------------
MAB_3596c|M.abscessus_ATCC_199      ------------