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TAVFDEGSAPESDGDSVTTRLLDATEKLLADKGIRATTMTDVAEEAGVSRSWLYRHFPDKPTLVGAAIIR LIEVSWAQSAAELADIDGFEARLVAGVKIGRRAYDDPGTLLMRIRLREPEEFMACAGTGVQGLVPDLAGF WRPYLEAARDTGEIHALTDIEEASEWIARVMISLGSVPGNRIDPDDPASLRRHFRRYVLPALRIAPVK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2606c | - | - | 100% (209) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0098 | - | 1e-12 | 28.88% (187) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0530 | - | 4e-12 | 28.21% (195) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 3e-06 | 34.62% (78) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2304 | - | 1e-57 | 52.04% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 9e-08 | 25.68% (183) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01733 | - | 5e-05 | 37.70% (61) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_3161 | - | 7e-16 | 30.10% (196) | transcriptional regulatory protein |
| M. avium 104 | MAV_1333 | - | 6e-16 | 29.76% (168) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4953 | - | 4e-66 | 61.78% (191) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3720 | - | 6e-17 | 32.34% (167) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0934 | - | 6e-12 | 25.00% (168) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4342 | - | 1e-56 | 49.50% (202) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2304|M.gilvum_PYR-GCK ---------------------------MSMSVGAFANSAPADQVTSPVAD
Mvan_4342|M.vanbaalenii_PYR-1 ---------------------------MSMSVGTVPNSAGSNSAASARAE
MSMEG_4953|M.smegmatis_MC2_155 -----------------------------MTNATAP--------------
MAB_2606c|M.abscessus_ATCC_199 -------------------------MTAVFDEGSAPESDG----------
MAV_1333|M.avium_104 ---------------------------MSTDVSPAT--------------
MUL_0934|M.ulcerans_Agy99 -----------------MPPPDELVMPQSAALPQAT--------------
TH_3720|M.thermoresistible__bu -----------------------------VTEATAL--------------
MMAR_3161|M.marinum_M ---------------------------MRWGAAAPSDR------------
Rv1255c|M.tuberculosis_H37Rv ---------------------------MAGTDWLSARR------------
Mb2534|M.bovis_AF2122/97 -------------------------MTASAPDGRPGQPEATNRRSQ----
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
Mflv_2304|M.gilvum_PYR-GCK PPVEPKARTVRDRLIDAAEQCLTAKGIRATTVSEVAEVAGVSRGWLYRHF
Mvan_4342|M.vanbaalenii_PYR-1 P------GSVRDRLIDAAEQCLTAKGIRATTVSEVAEVAGVSRGWLYRHF
MSMEG_4953|M.smegmatis_MC2_155 -------RSVRDRLIDAAETCLRAKGIRATTVSEVAEAAGVSRGWLYRHF
MAB_2606c|M.abscessus_ATCC_199 -------DSVTTRLLDATEKLLADKGIRATTMTDVAEEAGVSRSWLYRHF
MAV_1333|M.avium_104 --------DTRELIVAAAFTCFGRQGLQKATIVDIAKQAGVSRSTIYEYF
MUL_0934|M.ulcerans_Agy99 --------DTRELIIGSAYVCFRRQGFQKTTIVDIARLANVSRSTIYEYF
TH_3720|M.thermoresistible__bu --------ETREAIIMGAFACFRTYGLRKTTIVDIARKAEVSRSTVYEYF
MMAR_3161|M.marinum_M -------DSARDRLLDAAERCLESCGVVGTTMEDIGRTAGVSRATVYRYF
Rv1255c|M.tuberculosis_H37Rv ------TELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYF
Mb2534|M.bovis_AF2122/97 -----LKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHF
MLBr_01733|M.leprae_Br4923 ERWREHRKKVRGEIVDAAFRALDRLG-PEVSVREIAEEAGTAKPKIYRHF
:: .: : . : ::. * : :*.:*
Mflv_2304|M.gilvum_PYR-GCK PDKSELLGAAIVRLNDAFWTESRTRLDSVTGLDEQIAAGVALARKESETP
Mvan_4342|M.vanbaalenii_PYR-1 PDKAELLGAAIVRLNDAFWSESRTRLDAVAGLDQQIAVGVELARKESETP
MSMEG_4953|M.smegmatis_MC2_155 PDKVSLLGAAIVRLNDAYWSDAHAFLAAYDGLDEKIAAGIRYGRTAYDDP
MAB_2606c|M.abscessus_ATCC_199 PDKPTLVGAAIIRLIEVSWAQSAAELADIDGFEARLVAGVKIGRRAYDDP
MAV_1333|M.avium_104 SDKAAIVEACAEHASERFYREMAKAMDRGGTLEERLCAAAVFVTQARR--
MUL_0934|M.ulcerans_Agy99 RDKAAIMEGCAERASEQFYREMSKAMDRGGSLQEKLCQAAVFVTQSRQ--
TH_3720|M.thermoresistible__bu PDKAAIVEACAEAASERFYRNMAKVVNRGEDLEDKLVRACVFVTQARR--
MMAR_3161|M.marinum_M PNREAVMSGVIIRAAERYLDRINPRIAEHTDLGSALVDFVEYTVEAARRE
Rv1255c|M.tuberculosis_H37Rv DSREALRTAYVHRETRRLGREIMVKIADVVEPAERLLVSITTTLRMVRDN
Mb2534|M.bovis_AF2122/97 PNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALG-
MLBr_01733|M.leprae_Br4923 TDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDK
.: : :
Mflv_2304|M.gilvum_PYR-GCK GALVLKLRQEEPEAFTACVGLGVRGLIPEIAAFWEPYIQAAVDRGEIHAD
Mvan_4342|M.vanbaalenii_PYR-1 GALVLKLRQEEPEAFTACVGLGVRGLIPEIAAFWVPYIQAAVDRGEIHPD
MSMEG_4953|M.smegmatis_MC2_155 GALLMKLRLDEPEEFAACAGAGVQGLVPDLAAFWTRYLLAARDTGEIHPN
MAB_2606c|M.abscessus_ATCC_199 GTLLMRIRLREPEEFMACAGTGVQGLVPDLAGFWRPYLEAARDTGEIHAL
MAV_1333|M.avium_104 --VIASEKYFDEDAISLLLTKDAAVLLRECVEFFAPYLAAARLTGEVRKD
MUL_0934|M.ulcerans_Agy99 --TIASAKYFDQDAISLLLTKDSAVLLRECIDFFAPYLAAAKLTGEVRKD
TH_3720|M.thermoresistible__bu --VVQGEKYFDEEEVSILLTRDSAVLLKECADFIAPYLSAGRVTGEVRKD
MMAR_3161|M.marinum_M EIIGLLFGSDEELAGVGLAAGTSTSLFELVTEFLRPIFR--RHWSYVEPG
Rv1255c|M.tuberculosis_H37Rv PALAAWFTTTRPP-----IGGEMAGRSEVIAALAAAFLNSLGPDD----P
Mb2534|M.bovis_AF2122/97 EADLIRIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELN-------P
MLBr_01733|M.leprae_Br4923 HPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELNRA
:
Mflv_2304|M.gilvum_PYR-GCK TDRAEAAEWIARITMSLATVPGEQCDVDDHESVLRHARRYIVAAFRSD--
Mvan_4342|M.vanbaalenii_PYR-1 TNSAEAAEWIARIMMSLATVPGEQCNVDDHDSVLRHARRYIVAALRSD--
MSMEG_4953|M.smegmatis_MC2_155 TDIAEAAEWVARVVISFATVPGEQLDASDTGAVLTHLRRYVMPGLRAE--
MAB_2606c|M.abscessus_ATCC_199 TDIEEASEWIARVMISLGSVPGNRIDPDDPASLRRHFRRYVLPALRIA--
MAV_1333|M.avium_104 LDVEAAGEWFARILFSLFSTPSPTLNLDDPDVTAEFVRAHVVRGFASE--
MUL_0934|M.ulcerans_Agy99 LDVQAAAEWFARILFSLFSTPSPIRDMDDAQAVTEFVRAHVVDGFSDSR-
TH_3720|M.thermoresistible__bu LDIPKASEWVARILFSLFNTPSPTIDMSDDGAVADFVRSFVLRGFVDD--
MMAR_3161|M.marinum_M VSVDDAAEWVLRTILSLLTVRGPRERSRD--GLRTFLSRFLLPAILAS--
Rv1255c|M.tuberculosis_H37Rv TTVERRARWVVRMLTSLLMFPG-RDEADERAMIAEFVVPIVTPASAAAR-
Mb2534|M.bovis_AF2122/97 GLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLRAMTVAA-
MLBr_01733|M.leprae_Br4923 ASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVIVG
. .
Mflv_2304|M.gilvum_PYR-GCK ----------PAGT------------
Mvan_4342|M.vanbaalenii_PYR-1 ----------PNQ-------------
MSMEG_4953|M.smegmatis_MC2_155 ----------PAS-------------
MAB_2606c|M.abscessus_ATCC_199 ----------PVK-------------
MAV_1333|M.avium_104 ---------RPRRR------------
MUL_0934|M.ulcerans_Agy99 --------WRPARGVSKVH-------
TH_3720|M.thermoresistible__bu ---------RPHRGRRSSAG------
MMAR_3161|M.marinum_M ---------DHCRPM-----------
Rv1255c|M.tuberculosis_H37Rv --------KAGHPGPE----------
Mb2534|M.bovis_AF2122/97 --------LSAADRCL----------
MLBr_01733|M.leprae_Br4923 TAETLGISMNPDRPIHDAVPLDRSAS