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PPPDELVMPQSAALPQATDTRELIIGSAYVCFRRQGFQKTTIVDIARLANVSRSTIYEYFRDKAAIMEGC AERASEQFYREMSKAMDRGGSLQEKLCQAAVFVTQSRQTIASAKYFDQDAISLLLTKDSAVLLRECIDFF APYLAAAKLTGEVRKDLDVQAAAEWFARILFSLFSTPSPIRDMDDAQAVTEFVRAHVVDGFSDSRWRPAR GVSKVH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0934 | - | - | 100% (217) | transcriptional regulator |
| M. ulcerans Agy99 | MUL_4837 | - | 9e-08 | 24.19% (186) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_4875 | - | 5e-07 | 26.92% (78) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 4e-07 | 27.23% (191) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2304 | - | 1e-21 | 27.67% (206) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 5e-07 | 27.23% (191) | transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0098 | - | 1e-12 | 26.34% (186) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4251 | - | 1e-115 | 99.04% (209) | transcriptional regulator |
| M. avium 104 | MAV_1333 | - | 4e-81 | 74.11% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4953 | - | 6e-17 | 26.56% (192) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3720 | - | 2e-66 | 62.56% (195) | PUTATIVE transcriptional regulator, TetR family protein |
| M. vanbaalenii PYR-1 | Mvan_4342 | - | 6e-19 | 26.04% (192) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0934|M.ulcerans_Agy99 MPPPDELVMPQSAALPQAT--------------------DTRELIIGSAY
MMAR_4251|M.marinum_M --------MPQSAALPQAT--------------------DTRELIIGSAY
MAV_1333|M.avium_104 ----------MSTDVSPAT--------------------DTRELIVAAAF
TH_3720|M.thermoresistible__bu ------------VTEATAL--------------------ETREAIIMGAF
Mflv_2304|M.gilvum_PYR-GCK --------MSMSVGAFANSAPADQVTSPVADPPVEPKARTVRDRLIDAAE
Mvan_4342|M.vanbaalenii_PYR-1 --------MSMSVGTVPNSAGSNSAASARAEP------GSVRDRLIDAAE
MSMEG_4953|M.smegmatis_MC2_155 ----------MTNATAP---------------------RSVRDRLIDAAE
Mb1561|M.bovis_AF2122/97 --------MSRASARRRRAVSDEDK-------------SQRRDEILAAAK
Rv1534|M.tuberculosis_H37Rv --------MSRASARRRRAVSDEDK-------------SQRRDEILAAAK
MAB_0098|M.abscessus_ATCC_1997 --------MKLVKTTGPRG--------------------EVPEPIVAAVA
: :: ..
MUL_0934|M.ulcerans_Agy99 VCFRRQGFQKTTIVDIARLANVSRSTIYEYFRDKAAIMEGCAERASEQFY
MMAR_4251|M.marinum_M VCFRRQGFQKTTIVDIARLANVSRSTIYEYFRDKAAIMEGCAERASEQFY
MAV_1333|M.avium_104 TCFGRQGLQKATIVDIAKQAGVSRSTIYEYFSDKAAIVEACAEHASERFY
TH_3720|M.thermoresistible__bu ACFRTYGLRKTTIVDIARKAEVSRSTVYEYFPDKAAIVEACAEAASERFY
Mflv_2304|M.gilvum_PYR-GCK QCLTAKGIRATTVSEVAEVAGVSRGWLYRHFPDKSELLGAAIVRLNDAFW
Mvan_4342|M.vanbaalenii_PYR-1 QCLTAKGIRATTVSEVAEVAGVSRGWLYRHFPDKAELLGAAIVRLNDAFW
MSMEG_4953|M.smegmatis_MC2_155 TCLRAKGIRATTVSEVAEAAGVSRGWLYRHFPDKVSLLGAAIVRLNDAYW
Mb1561|M.bovis_AF2122/97 IVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALR
Rv1534|M.tuberculosis_H37Rv IVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALR
MAB_0098|M.abscessus_ATCC_1997 QTLVRSGIQRFSLSAAADEAGVSRGTIYNWFGGKKEAIDVAVGFIAGAFI
: *:: :: * * :: . :* * .* .
MUL_0934|M.ulcerans_Agy99 REMSKAMDRGGSLQEK----LCQAAVFVTQSRQ----TIASAKYFDQDAI
MMAR_4251|M.marinum_M REMSKAMDRGGSLQEK----LCQAAVFVTQSRQ----AIASAKYFDEDAI
MAV_1333|M.avium_104 REMAKAMDRGGTLEER----LCAAAVFVTQARR----VIASEKYFDEDAI
TH_3720|M.thermoresistible__bu RNMAKVVNRGEDLEDK----LVRACVFVTQARR----VVQGEKYFDEEEV
Mflv_2304|M.gilvum_PYR-GCK TESRTRLDSVTGLDEQ----IAAGVALARKESETPGALVLKLRQEEPEAF
Mvan_4342|M.vanbaalenii_PYR-1 SESRTRLDAVAGLDQQ----IAVGVELARKESETPGALVLKLRQEEPEAF
MSMEG_4953|M.smegmatis_MC2_155 SDAHAFLAAYDGLDEK----IAAGIRYGRTAYDDPGALLMKLRLDEPEEF
Mb1561|M.bovis_AF2122/97 AHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYAL
Rv1534|M.tuberculosis_H37Rv AHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYAL
MAB_0098|M.abscessus_ATCC_1997 ELFAGAVSAKTTLTDQ------VGEAAVRISDHRAWSDRLDPTLHVSNVL
: : . .
MUL_0934|M.ulcerans_Agy99 SLLLTKDSAVLLRECIDFFAPYLAAAKLTGEVRKDLDVQAAAEWFARILF
MMAR_4251|M.marinum_M SLLLTKDSAVLLRECIDFFAPYLAAAKLTGEVRKDLDVQAAAEWFARILF
MAV_1333|M.avium_104 SLLLTKDAAVLLRECVEFFAPYLAAARLTGEVRKDLDVEAAGEWFARILF
TH_3720|M.thermoresistible__bu SILLTRDSAVLLKECADFIAPYLSAGRVTGEVRKDLDIPKASEWVARILF
Mflv_2304|M.gilvum_PYR-GCK TACVGLGVRGLIPEIAAFWEPYIQAAVDRGEIHADTDRAEAAEWIARITM
Mvan_4342|M.vanbaalenii_PYR-1 TACVGLGVRGLIPEIAAFWVPYIQAAVDRGEIHPDTNSAEAAEWIARIMM
MSMEG_4953|M.smegmatis_MC2_155 AACAGAGVQGLVPDLAAFWTRYLLAARDTGEIHPNTDIAEAAEWVARVVI
Mb1561|M.bovis_AF2122/97 GGRFEEHLGGIYERFIDDIEAVVVAAQRRGEVVEAP-SRMAAYTLAALVG
Rv1534|M.tuberculosis_H37Rv GGRFEEHLGGIYERFIDDIEAVVVAAQRRGEVVEAP-SRMAAYTLAALVG
MAB_0098|M.abscessus_ATCC_1997 ELVLEECGDDLMRRSVEFWVPQVEAAKHRGEIGGDVDATEAAEWIMRTLM
: : *. **: *. .
MUL_0934|M.ulcerans_Agy99 SLFSTPSPIRDMDDAQAVTEFVRAHVVDGFSDSRWRPARGVSKVH--
MMAR_4251|M.marinum_M SLFSTPSPIRDMDDAQAVTEFVRAHVVDGFSDSRWRPARGVSKVH--
MAV_1333|M.avium_104 SLFSTPSPTLNLDDPDVTAEFVRAHVVRGFASE--RPRRR-------
TH_3720|M.thermoresistible__bu SLFNTPSPTIDMSDDGAVADFVRSFVLRGFVDD--RPHRGRRSSAG-
Mflv_2304|M.gilvum_PYR-GCK SLATVPGEQCDVDDHESVLRHARRYIVAAFRSD---PAGT-------
Mvan_4342|M.vanbaalenii_PYR-1 SLATVPGEQCNVDDHDSVLRHARRYIVAALRSD---PNQ--------
MSMEG_4953|M.smegmatis_MC2_155 SFATVPGEQLDASDTGAVLTHLRRYVMPGLRAE---PAS--------
Mb1561|M.bovis_AF2122/97 QLAHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART
Rv1534|M.tuberculosis_H37Rv QLAHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART
MAB_0098|M.abscessus_ATCC_1997 SIEVLPAISVDLTDPNRVRRYFSRFILRGLA----------------
.: : . . :: .: