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MSMSVGTVPNSAGSNSAASARAEPGSVRDRLIDAAEQCLTAKGIRATTVSEVAEVAGVSRGWLYRHFPDK AELLGAAIVRLNDAFWSESRTRLDAVAGLDQQIAVGVELARKESETPGALVLKLRQEEPEAFTACVGLGV RGLIPEIAAFWVPYIQAAVDRGEIHPDTNSAEAAEWIARIMMSLATVPGEQCNVDDHDSVLRHARRYIVA ALRSDPNQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4342 | - | - | 100% (218) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3399 | - | 6e-13 | 29.45% (163) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0369 | - | 1e-10 | 26.20% (187) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3587c | - | 3e-07 | 23.78% (143) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2304 | - | 1e-102 | 84.23% (222) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 3e-08 | 26.11% (180) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01733 | - | 1e-07 | 35.06% (77) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2606c | - | 9e-57 | 49.50% (202) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4251 | - | 2e-18 | 25.52% (192) | transcriptional regulator |
| M. avium 104 | MAV_1333 | - | 9e-20 | 28.27% (191) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4953 | - | 4e-71 | 64.77% (193) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_4573 | - | 3e-17 | 30.00% (190) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0934 | - | 4e-19 | 26.04% (192) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4342|M.vanbaalenii_PYR-1 ---------------------------MSMSVGTVPNSAGSNSAASARAE
Mflv_2304|M.gilvum_PYR-GCK ---------------------------MSMSVGAFANSAPADQVTSPVAD
MSMEG_4953|M.smegmatis_MC2_155 -----------------------------MTNATAP--------------
MAB_2606c|M.abscessus_ATCC_199 -------------------------MTAVFDEGSAPESDG----------
MMAR_4251|M.marinum_M -----------------------------MPQSAALPQA-----------
MUL_0934|M.ulcerans_Agy99 ---------------------MPPPDELVMPQSAALPQA-----------
MAV_1333|M.avium_104 -------------------------------MSTDVSPA-----------
TH_4573|M.thermoresistible__bu ------------------------MATQRATADVEEQHE-----------
Rv1255c|M.tuberculosis_H37Rv ---------------------------MAGTDWLSARRT-----------
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
Mb3587c|M.bovis_AF2122/97 -----------------------------MDRVAGQVNS-----------
Mvan_4342|M.vanbaalenii_PYR-1 P------GSVRDRLIDAAEQCLTAKGIRATTVSEVAEVAGVSRGWLYRHF
Mflv_2304|M.gilvum_PYR-GCK PPVEPKARTVRDRLIDAAEQCLTAKGIRATTVSEVAEVAGVSRGWLYRHF
MSMEG_4953|M.smegmatis_MC2_155 -------RSVRDRLIDAAETCLRAKGIRATTVSEVAEAAGVSRGWLYRHF
MAB_2606c|M.abscessus_ATCC_199 -------DSVTTRLLDATEKLLADKGIRATTMTDVAEEAGVSRSWLYRHF
MMAR_4251|M.marinum_M -------TDTRELIIGSAYVCFRRQGFQKTTIVDIARLANVSRSTIYEYF
MUL_0934|M.ulcerans_Agy99 -------TDTRELIIGSAYVCFRRQGFQKTTIVDIARLANVSRSTIYEYF
MAV_1333|M.avium_104 -------TDTRELIVAAAFTCFGRQGLQKATIVDIAKQAGVSRSTIYEYF
TH_4573|M.thermoresistible__bu -------SDRRDQILEAANACFAQLGIHRTSVQDVARAANVSRGTVYRYF
Rv1255c|M.tuberculosis_H37Rv -------ELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYF
MLBr_01733|M.leprae_Br4923 ERWREHRKKVRGEIVDAAFRALDRLG-PEVSVREIAEEAGTAKPKIYRHF
Mb3587c|M.bovis_AF2122/97 ---------RRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHF
:: : : . : ::* *. :*.:*
Mvan_4342|M.vanbaalenii_PYR-1 PDKAELLGAAIVRLNDAFWSESRTRLDAVAGLDQQIAVGVELARKESETP
Mflv_2304|M.gilvum_PYR-GCK PDKSELLGAAIVRLNDAFWTESRTRLDSVTGLDEQIAAGVALARKESETP
MSMEG_4953|M.smegmatis_MC2_155 PDKVSLLGAAIVRLNDAYWSDAHAFLAAYDGLDEKIAAGIRYGRTAYDDP
MAB_2606c|M.abscessus_ATCC_199 PDKPTLVGAAIIRLIEVSWAQSAAELADIDGFEARLVAGVKIGRRAYDDP
MMAR_4251|M.marinum_M RDKAAIMEGCAERASEQFYREMSKAMDRGGSLQEKLCQAAVFVTQSR--Q
MUL_0934|M.ulcerans_Agy99 RDKAAIMEGCAERASEQFYREMSKAMDRGGSLQEKLCQAAVFVTQSR--Q
MAV_1333|M.avium_104 SDKAAIVEACAEHASERFYREMAKAMDRGGTLEERLCAAAVFVTQAR--R
TH_4573|M.thermoresistible__bu EDRTILIEAAIEYGAQKFYQEIAAAMAKKSTLAEQLGAMAETHAKIL--L
Rv1255c|M.tuberculosis_H37Rv DSREALRTAYVHRETRRLGREIMVKIADVVEPAERLLVSITTTLRMVRDN
MLBr_01733|M.leprae_Br4923 TDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDK
Mb3587c|M.bovis_AF2122/97 ASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHH
.: : : .:
Mvan_4342|M.vanbaalenii_PYR-1 GALVLKLRQEEPEAFTACVGLGVRGLIPEIAAFWVPYIQ----------A
Mflv_2304|M.gilvum_PYR-GCK GALVLKLRQEEPEAFTACVGLGVRGLIPEIAAFWEPYIQ----------A
MSMEG_4953|M.smegmatis_MC2_155 GALLMKLRLDEPEEFAACAGAGVQGLVPDLAAFWTRYLL----------A
MAB_2606c|M.abscessus_ATCC_199 GTLLMRIRLREPEEFMACAGTGVQGLVPDLAGFWRPYLE----------A
MMAR_4251|M.marinum_M AIASAKYFDEDAISLL--LTKDSAVLLRECIDFFAPYLA----------A
MUL_0934|M.ulcerans_Agy99 TIASAKYFDQDAISLL--LTKDSAVLLRECIDFFAPYLA----------A
MAV_1333|M.avium_104 VIASEKYFDEDAISLL--LTKDAAVLLRECVEFFAPYLA----------A
TH_4573|M.thermoresistible__bu DHRTRNRLMTDDAELMRHMIADADAAVRRTTEFLMPYVQ----------Q
Rv1255c|M.tuberculosis_H37Rv PALAAWFTTTRP-----PIGGEMAGRSEVIAALAAAFLN----------S
MLBr_01733|M.leprae_Br4923 HPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELNRA
Mb3587c|M.bovis_AF2122/97 HAQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLN----------Q
.
Mvan_4342|M.vanbaalenii_PYR-1 AVDRGEIHPDTNSAEAAEWIAR-------------IMMSLATVPG-EQCN
Mflv_2304|M.gilvum_PYR-GCK AVDRGEIHADTDRAEAAEWIAR-------------ITMSLATVPG-EQCD
MSMEG_4953|M.smegmatis_MC2_155 ARDTGEIHPNTDIAEAAEWVAR-------------VVISFATVPG-EQLD
MAB_2606c|M.abscessus_ATCC_199 ARDTGEIHALTDIEEASEWIAR-------------VMISLGSVPG-NRID
MMAR_4251|M.marinum_M AKLTGEVRKDLDVQAAAEWFAR-------------ILFSLFSTPS-PIRD
MUL_0934|M.ulcerans_Agy99 AKLTGEVRKDLDVQAAAEWFAR-------------ILFSLFSTPS-PIRD
MAV_1333|M.avium_104 ARLTGEVRKDLDVEAAGEWFAR-------------ILFSLFSTPS-PTLN
TH_4573|M.thermoresistible__bu AKERGEVGSGVDVKAASEWLAR-------------IIYSFTTVNEGLTFD
Rv1255c|M.tuberculosis_H37Rv LGP----DDPTTVERRARWVVR-------------MLTSLLMFPG--RDE
MLBr_01733|M.leprae_Br4923 ASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVIVG
Mb3587c|M.bovis_AF2122/97 GIEEGYFRPDLDVDLVYRFIRD---------------TTWVSVRWYRPGG
.:
Mvan_4342|M.vanbaalenii_PYR-1 VDDHDSVLRHARRYIVAALRSDPNQ---------
Mflv_2304|M.gilvum_PYR-GCK VDDHESVLRHARRYIVAAFRSDPAGT--------
MSMEG_4953|M.smegmatis_MC2_155 ASDTGAVLTHLRRYVMPGLRAEPAS---------
MAB_2606c|M.abscessus_ATCC_199 PDDPASLRRHFRRYVLPALRIAPVK---------
MMAR_4251|M.marinum_M MDDAQAVTEFVRAHVVDGFSDSRWRPARGVSKVH
MUL_0934|M.ulcerans_Agy99 MDDAQAVTEFVRAHVVDGFSDSRWRPARGVSKVH
MAV_1333|M.avium_104 LDDPDVTAEFVRAHVVRGFASE--RPRRR-----
TH_4573|M.thermoresistible__bu MSKPATVRRYVERFAVNGLR--------------
Rv1255c|M.tuberculosis_H37Rv ADERAMIAEFVVPIVTPASAAARKAGHPGPE---
MLBr_01733|M.leprae_Br4923 TAETLGISMNPDRPIHDAVPLDRSAS--------
Mb3587c|M.bovis_AF2122/97 PLTAQQVGQQYLAIVLGGITKEGV----------
.