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M. tuberculosis H37Rv Rv3249c (-)

annotation: POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
coordinates: 3629752 - 3630387
length: 211

STPSATVAPVKRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLA
QGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPDLLQLITTDSAPI
ITRASARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv3249c - - 100% (211) POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
M. tuberculosis H37Rv Rv1255c - 3e-09 26.60% (188) transcriptional regulatory protein
M. tuberculosis H37Rv Rv0302 - 2e-06 26.50% (117) TetR/ACRR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3277c - 1e-115 100.00% (211) TetR family transcriptional regulator
M. gilvum PYR-GCK Mflv_4718 - 1e-84 74.64% (209) TetR family transcriptional regulator
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_3596c - 1e-70 65.13% (195) TetR family transcriptional regulator
M. marinum M MMAR_1294 - 1e-103 92.16% (204) TetR family transcriptional regulator
M. avium 104 MAV_4212 - 3e-94 86.50% (200) putative transcriptional regulatory protein
M. smegmatis MC2 155 MSMEG_1842 - 2e-83 72.99% (211) transcriptional regulator, TetR family protein
M. thermoresistible (build 8) TH_0467 - 4e-84 78.68% (197) POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99 MUL_2593 - 1e-102 91.67% (204) TetR family transcriptional regulator
M. vanbaalenii PYR-1 Mvan_1745 - 2e-84 75.76% (198) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Rv3249c|M.tuberculosis_H37Rv        -----------------------------------MSTPSAT----VAPV
Mb3277c|M.bovis_AF2122/97           -----------------------------------MSTPSAT----VAPV
MMAR_1294|M.marinum_M               ----------------------------------MIDTNSFAKRDIVGPV
MUL_2593|M.ulcerans_Agy99           ---------------MPRLRCGKGGLRDGGGGSTVIDTNSFAKRDIVGPV
MAV_4212|M.avium_104                -------------------------------------------------M
Mflv_4718|M.gilvum_PYR-GCK          -MTAQPIATSARVATRHADQRRADTRARGASLGPVRATVIVAPVGG-GND
Mvan_1745|M.vanbaalenii_PYR-1       -MRATHRAEPC----RHARSRNTASQGTAVTASAGPGTITVARVGL-SND
TH_0467|M.thermoresistible__bu      ---------------------------------------VVSRR-----D
MSMEG_1842|M.smegmatis_MC2_155      MIHAVTHAVAG---------AQFGAPARVVRGPLTAESDIVARVSRPRAK
MAB_3596c|M.abscessus_ATCC_199      -MTDVLP--------------GRDALTSASVPARLPGVTRPDALRAGGSS
                                                                                      

Rv3249c|M.tuberculosis_H37Rv        KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
Mb3277c|M.bovis_AF2122/97           KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
MMAR_1294|M.marinum_M               KRVPYAEASRVLLRDSVLDAMRDLLLTRDWSAITLSDVARSAGISRQTIY
MUL_2593|M.ulcerans_Agy99           KRVPYAEASRVLLRDSVLDAMRDLLFTRDWSAITLSDVARSAGISRQTIY
MAV_4212|M.avium_104                KRMPYAEASRALLRDSVLDAMRDLLVTRDWSAITLSDVARAAGISRQTIY
Mflv_4718|M.gilvum_PYR-GCK          KRISYAEASRVLLRDSILDGMREMLLARDWSQITLSDVAKAAGISRQTIY
Mvan_1745|M.vanbaalenii_PYR-1       KRVSYAEASRVLLRDSILDGMREMLLTRDWSAITLSDVAKAAGISRQTIY
TH_0467|M.thermoresistible__bu      KRVPYAEASRVLLRDSILDGMRELLQTRDWSQITLADVAKAAGISRQTIY
MSMEG_1842|M.smegmatis_MC2_155      QRMPYAEASRVLLRDSILDGMRDLLLTRDWSAITLSHVAQAAGVSRQTIY
MAB_3596c|M.abscessus_ATCC_199      HRVPYAEAARALLRESVLDALGDLLRQRDWSAVTMSDVSRRAGVSRQTLY
                                    :*:.****:*.***:*:**.: ::*  **** :*::.*:: **:****:*

Rv3249c|M.tuberculosis_H37Rv        NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
Mb3277c|M.bovis_AF2122/97           NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
MMAR_1294|M.marinum_M               NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
MUL_2593|M.ulcerans_Agy99           NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
MAV_4212|M.avium_104                NEFGSRQGLAQGYALRLADRLVDTIHEALDAHVGNIYESFLDAFRRFFAD
Mflv_4718|M.gilvum_PYR-GCK          NEFGSRQGLAQGYAMRLADRLVDQIHAAIDNNVGDMYAAFLQGFRDFFVE
Mvan_1745|M.vanbaalenii_PYR-1       NEFGSRQGLAQGYAMRLADRLVDQIHGAINGNAGDVYAAFLQGFRDFFVE
TH_0467|M.thermoresistible__bu      NEFGSRQGLAQGYALRLADRLVDEVDEAIANNVGDIHAAFLAGFRKFFAE
MSMEG_1842|M.smegmatis_MC2_155      NEFGSRQGLAEGYAMRLADRLVDAVDDAINNNVGDVYAAFLEGFRAFFAE
MAB_3596c|M.abscessus_ATCC_199      NEFGSRQGLAQGYALRLAHRLVDAVGDAIYAHVGDIHGALHSGFADFFAE
                                    **********:***:***.**** :  ::  :.*:.: ::  .*  ** :

Rv3249c|M.tuberculosis_H37Rv        SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
Mb3277c|M.bovis_AF2122/97           SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
MMAR_1294|M.marinum_M               SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATS
MUL_2593|M.ulcerans_Agy99           SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATS
MAV_4212|M.avium_104                AAADPLVTSLRTGVAKPDLLQLITTDSAVIITRASARLASALTHTWVSTT
Mflv_4718|M.gilvum_PYR-GCK          SAADPLVISLLTGSSKPDLLQLITTDSAPIINHCSSRLTESLMGSWVRCS
Mvan_1745|M.vanbaalenii_PYR-1       SAADPLVISLLTGTSKPDLLQLITTDSAPIINHCSSRLTESFMSSWVRVS
TH_0467|M.thermoresistible__bu      SAADPLVISLLTGSAKPDLLQLITTDSAPIITRASQRLTESFQSSWVRAS
MSMEG_1842|M.smegmatis_MC2_155      SAADPLVISLLTGAAKPDLLQIITIGSGPIITRCSERLTATFQSSWIKAS
MAB_3596c|M.abscessus_ATCC_199      SAADPMVISLLTGEAKPELMRIVTVDSALIVVPASARLTESFMNSWVAAS
                                    :****:* ** ** :**:*::::* .*. *:  .* **: ::  :*:  :

Rv3249c|M.tuberculosis_H37Rv        DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
Mb3277c|M.bovis_AF2122/97           DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
MMAR_1294|M.marinum_M               DDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP
MUL_2593|M.ulcerans_Agy99           DDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP
MAV_4212|M.avium_104                DEDAGVLARAIVRLALSYVSMPPEADHDVAADLARLMTPFAERHGVVNVG
Mflv_4718|M.gilvum_PYR-GCK          EEDAGVLSRAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVVADP
Mvan_1745|M.vanbaalenii_PYR-1       QEDAGVLARAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVIDP-
TH_0467|M.thermoresistible__bu      EEDAGVLARAIVRLAMSYVSMPPEADHDVAHDLARLMTPFAERYGVIEEV
MSMEG_1842|M.smegmatis_MC2_155      DDDAGVLARAIVRLAMSYVSMPPEADHDVAGDLARLMSPFAERYGVIDTP
MAB_3596c|M.abscessus_ATCC_199      QEDASILARSIVRLAISYVSMPPESDHDVALDMARLLSPFVETNALADKA
                                    ::**.:*:*:****.:**:*****:**:** *:***::**.*  .:    

Rv3249c|M.tuberculosis_H37Rv        ------------
Mb3277c|M.bovis_AF2122/97           ------------
MMAR_1294|M.marinum_M               ------------
MUL_2593|M.ulcerans_Agy99           ------------
MAV_4212|M.avium_104                ------------
Mflv_4718|M.gilvum_PYR-GCK          VEGGNSQVTRRP
Mvan_1745|M.vanbaalenii_PYR-1       ------------
TH_0467|M.thermoresistible__bu      ------------
MSMEG_1842|M.smegmatis_MC2_155      ------------
MAB_3596c|M.abscessus_ATCC_199      ------------

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv3249c	-	-	100% (211)	POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
M. tuberculosis H37Rv	Rv1255c	-	3e-09	26.60% (188)	transcriptional regulatory protein
M. tuberculosis H37Rv	Rv0302	-	2e-06	26.50% (117)	TetR/ACRR family transcriptional regulator