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RWGAAAPSDRDSARDRLLDAAERCLESCGVVGTTMEDIGRTAGVSRATVYRYFPNREAVMSGVIIRAAER YLDRINPRIAEHTDLGSALVDFVEYTVEAARREEIIGLLFGSDEELAGVGLAAGTSTSLFELVTEFLRPI FRRHWSYVEPGVSVDDAAEWVLRTILSLLTVRGPRERSRDGLRTFLSRFLLPAILASDHCRPM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3161 | - | - | 100% (204) | transcriptional regulatory protein |
| M. marinum M | MMAR_4185 | - | 5e-16 | 32.12% (193) | transcriptional regulatory protein |
| M. marinum M | MMAR_4418 | - | 8e-15 | 27.27% (187) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 1e-09 | 31.91% (94) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3024 | - | 3e-75 | 75.00% (184) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 2e-14 | 29.67% (182) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00316 | - | 4e-05 | 38.71% (62) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2043 | - | 4e-86 | 93.49% (169) | putative transcriptional regulator, TetR |
| M. avium 104 | MAV_1115 | - | 8e-20 | 30.35% (201) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4953 | - | 2e-18 | 29.69% (192) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_4364 | - | 5e-23 | 34.52% (197) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4487 | - | 4e-16 | 32.12% (193) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4911 | - | 1e-21 | 31.47% (197) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3161|M.marinum_M ----------MRWGAAAPSDRDSARDR---LLDAAERCLESCGVVGTTME
MAB_2043|M.abscessus_ATCC_1997 ------------------------------------------------ME
Mflv_3024|M.gilvum_PYR-GCK ----------------------MARDR---LLDAAETCLQSKGLSGTTME
MAV_1115|M.avium_104 -------MRRHGWSGDIPADDEEAVAR---ILTATRRAIDERG--TVSVS
Mvan_4911|M.vanbaalenii_PYR-1 -------MRRHGWAGNIPVDDDEAVSR---IVAAARASIDARG--TVSVS
TH_4364|M.thermoresistible__bu -------MRTHGWRGTPPRSDDEAVER---ILAATHRCVAERGG-QTTIA
Rv1255c|M.tuberculosis_H37Rv -------MAGTDWLSARR--TELAADR---ILDAAERLFTQRDPASIGMN
MUL_4487|M.ulcerans_Agy99 -------MGRTDWLAAHR--SEVAADR---ILDAAERLYTEHDPASIGMN
MSMEG_4953|M.smegmatis_MC2_155 --------------MTNATAPRSVRDR---LIDAAETCLRAKGIRATTVS
Mb2534|M.bovis_AF2122/97 -MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLE
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNR-ARILGVAYEAFATEG-LSVPID
:
MMAR_3161|M.marinum_M DIGRTAGVSRATVYRYFPNREAVMSGVIIRAAERYLDRINPRIAEHTDLG
MAB_2043|M.abscessus_ATCC_1997 DIGRTAGVSRATVYRYFPSREAVMSGVIIRAAERYLDRISPRIAAHADLG
Mflv_3024|M.gilvum_PYR-GCK DIARQAGVSRATVYRYFPSRESVVSGVIVRAAQRYLHRISGRISAHTDLG
MAV_1115|M.avium_104 QVASTLGVTRQTIYRYFPTHEALLGATALSAVEGFLDRLAAHLGSITDPT
Mvan_4911|M.vanbaalenii_PYR-1 EVATELGITRQTVYRYFPTLDALLTGTALSAVGGFLDRLAQDLASITDPA
TH_4364|M.thermoresistible__bu HVAAELGVSRATVYRYFPSTSALLQAAAVEGTRRFLHRMAERLGRIDDVA
Rv1255c|M.tuberculosis_H37Rv EIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEPA
MUL_4487|M.ulcerans_Agy99 EIARAAGCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDIDDPR
MSMEG_4953|M.smegmatis_MC2_155 EVAEAAGVSRGWLYRHFPDKVSLLGAAIVRLNDAYWSDAHAFLAAYDGLD
Mb2534|M.bovis_AF2122/97 DIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLA
MLBr_00316|M.leprae_Br4923 EIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGPGE
.:. * :**:* ::
MMAR_3161|M.marinum_M SALVDFVEYTVEAARREEIIGLLFGSDEELAGVGLAAGTSTSLFELVTEF
MAB_2043|M.abscessus_ATCC_1997 SALVDFVEYTVEAARREEIIGLLFGSDEELAGVGLAAGTSTSLFEIVTEF
Mflv_3024|M.gilvum_PYR-GCK SAILDFVAVTVRAARREPIIGVLFGSDDELAGVGLAEGTSVALFELVADF
MAV_1115|M.avium_104 EAVVEGIAYTFEQLAHDRYLSLVFQPG--KASAFTAGVTSDIAISFGRS-
Mvan_4911|M.vanbaalenii_PYR-1 EAVVEGIAYTLEQLPHDRYLGLVMQPG--KASAFAAGVTSDVAISFGRS-
TH_4364|M.thermoresistible__bu DAIIEGVVQTVAAVPNEPYLRLLLDE---PSHVLLRDVTSESAREIGKSM
Rv1255c|M.tuberculosis_H37Rv ERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAG-RSEVIAALAAAF
MUL_4487|M.ulcerans_Agy99 DQLITSITATLRMVRQRPALAAWFASTRPPIGGELAG-QSEVIAGLAAAF
MSMEG_4953|M.smegmatis_MC2_155 EKIAAGIRYGRTAYDDPGALLMKLRLDEPEEFAACAGAGVQGLVPDLAAF
Mb2534|M.bovis_AF2122/97 AALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQRQYVEVW
MLBr_00316|M.leprae_Br4923 ALFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAPDAEDAFLTILSDL
. :
MMAR_3161|M.marinum_M LRPIFRRHWS----YVEPGVSVDDAAEWVLRTILSLLTVRGPRERSRDG-
MAB_2043|M.abscessus_ATCC_1997 LRPIFTRHWS----CVEPGVSVDDAAEWVVRTILSLLTVRGPRERSRDG-
Mflv_3024|M.gilvum_PYR-GCK LRPVFAAHWD----QLEAGVSVDDAAEWILRTILSLLSVRGPRHRSPEG-
MAV_1115|M.avium_104 ILQRFEVDWG---AAGFADAGLDELVEVMLRTLQSLIVDPGRPPRTGAE-
Mvan_4911|M.vanbaalenii_PYR-1 ILERLNVDWA---GAGFSGQSLDELVEFMLRTLQSFILDPGGPDRHRGE-
TH_4364|M.thermoresistible__bu LLESTSVDWARLRPAAEIVDELDELIEWSLRIVQSFLTDPGDPPRSPDA-
Rv1255c|M.tuberculosis_H37Rv LNSLGPDDPT----------TVERRARWVVRMLTSLLMFPG---RDEAD-
MUL_4487|M.ulcerans_Agy99 LQSLGPEAPA----------AVERRARWTVRVIVSLLMFPG---QDEAD-
MSMEG_4953|M.smegmatis_MC2_155 WTRYLLAARDTG--EIHPNTDIAEAAEWVARVVISFATVPGEQLDASDTG
Mb2534|M.bovis_AF2122/97 VGVLRELNPG----------LAEADARLMAHAVFGLLNSTPHSMKAADSK
MLBr_00316|M.leprae_Br4923 LYAAQYAGTA--------------RTDVGVREVKSILVGCQAMEAYNSA-
: : .:
MMAR_3161|M.marinum_M -LRTFLSRFLLPAILASDHCRPM--------
MAB_2043|M.abscessus_ATCC_1997 -LRAFLSRFLLPAILAGDHARPM--------
Mflv_3024|M.gilvum_PYR-GCK -LDAFLRRFLLPALLADTQRCVTATIAE---
MAV_1115|M.avium_104 -LRRFLQDWVAPAVRAHAISR----------
Mvan_4911|M.vanbaalenii_PYR-1 -LRAFLHRWVAPAVELHHRSG--FPEQA---
TH_4364|M.thermoresistible__bu -LRAHLHRWLGPAIREWVASVGIDAEQSPPE
Rv1255c|M.tuberculosis_H37Rv -ERAMIAEFVVPIVTPASAAARKAGHPGPE-
MUL_4487|M.ulcerans_Agy99 -ERAMLEEFVAPVVTPFPTRR----------
MSMEG_4953|M.smegmatis_MC2_155 AVLTHLRRYVMPGLRAEPAS-----------
Mb2534|M.bovis_AF2122/97 PARTVRARAVLRAMTVAALSAADRCL-----
MLBr_00316|M.leprae_Br4923 -LAERVTDVVVDGLRAAR-------------
: :