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PFSGYPVAMSTTRPAIAPKSAHQAVSLPPAQRLLNTASELFAGQGIRAVGIDLILREAGVAKASLYSTYG SKDALVIAYLTNLDHADRNRWEQTVAGVEDPVQRVLTFFDLASRNAARRDFRGCLYANAATEYPGVELEP VRAHRAWLRSTLAGLLKQAGVGSPVALARRIQLLYDGALLGSKLERSTKPITAARDLVEELIELGRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4517 | - | - | 100% (208) | TetR-type transcriptional regulator of sulfur metabolism |
| M. smegmatis MC2 155 | MSMEG_6244 | - | 1e-17 | 30.68% (176) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2153 | - | 1e-17 | 34.07% (182) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3198c | - | 2e-20 | 34.65% (202) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2228 | - | 9e-07 | 31.17% (77) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3173c | - | 3e-20 | 34.65% (202) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2458c | - | 2e-65 | 62.89% (194) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2062 | - | 2e-11 | 33.33% (114) | hypothetical protein MMAR_2062 |
| M. avium 104 | MAV_2097 | - | 4e-16 | 33.71% (178) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3775 | - | 2e-17 | 34.66% (176) | PUTATIVE TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_2793 | - | 2e-07 | 26.67% (180) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4792 | - | 8e-17 | 33.91% (174) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4517|M.smegmatis_MC2_155 MPFSGYPVAMSTTRPAIAPKSAHQAVSLPPAQRLLNTASELFAGQGIRAV
MAB_2458c|M.abscessus_ATCC_199 ---------MSSATVPTAADSARTARVLGPADRLLQTATDLFATQGIRSV
TH_3775|M.thermoresistible__bu ------------------------MAETDDKNRVLATATTLFNERGVQAV
Mvan_4792|M.vanbaalenii_PYR-1 ------------------------MPAEDPRQRAIDAAVELFHREGFGAV
Mb3198c|M.bovis_AF2122/97 ------------MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINAT
Rv3173c|M.tuberculosis_H37Rv ------------MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINAT
MAV_2097|M.avium_104 ------------MSKRRDVKHVTTGGGRGARRRILDTATELFYRDGINAT
MMAR_2062|M.marinum_M -----------------MAIPEATTAAVPARERILGAAYDLFSRRGIRAV
MUL_2793|M.ulcerans_Agy99 ---------------------------MTARERLIESAIELLRRNGVAGT
Mflv_2228|M.gilvum_PYR-GCK ----------------MAGDWLAARRTEVAADRILDAAGELFAAQSAATV
* : :* *: . .
MSMEG_4517|M.smegmatis_MC2_155 GIDLILREAGVAKASLYSTYGSKDALVIAYLTNLDHADRN-RWEQTVAGV
MAB_2458c|M.abscessus_ATCC_199 GIDQILREAGVAKASLYSSFGSKDALVVAYLEELDQRDRN-RWNAAVAAQ
TH_3775|M.thermoresistible__bu GMDAIRDAAGISLKRLYSCFRSKADLVAAVLEQRDADVRR-AMTEYVQSR
Mvan_4792|M.vanbaalenii_PYR-1 GIDRLTTSIGMSKRTLYKYFDSKDDLLLAVLDSCEGMALR-DLPD--EDD
Mb3198c|M.bovis_AF2122/97 GVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE-ADK-MPKAS
Rv3173c|M.tuberculosis_H37Rv GVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE-ADK-MPKAS
MAV_2097|M.avium_104 GVERLAAEASVSKRTLYQHFPSKNAVVEEYLRGIQQAVGD-PIHPEADAT
MMAR_2062|M.marinum_M GTDEVIERAGVARATLYRHFATKDDLVLAVLQRREELWTFGLIEQKSRAR
MUL_2793|M.ulcerans_Agy99 GLADLLEHSGTARRSVYVNFPGGK---SELMTEATRTAGR-LMDSTLASI
Mflv_2228|M.gilvum_PYR-GCK GMHEIAAAAGCSRATLYRYFENREALYTAYVHRESYRLYR-EMTEQIMSF
* : . : :* : :
MSMEG_4517|M.smegmatis_MC2_155 E-DPVQRVLTFFDLASRNA-ARRDFRGCLYANAATEYPG---VELEPVRA
MAB_2458c|M.abscessus_ATCC_199 R-DPIAKVLTFFDLAATAA-ESRNFRGCLYANAATEFPG---LQLEPVRT
TH_3775|M.thermoresistible__bu AADPRDRILAVFDFLAHWF-AESDFRGCMFINTIGELGGTSTDVRRIARL
Mvan_4792|M.vanbaalenii_PYR-1 DSSPRDRILAVFDAQAKYC-TDPDFAGCFFVNIATEFRDPDHRAVRIAAD
Mb3198c|M.bovis_AF2122/97 NATPRERLLALFDRPNR---GDGRMRGCPFHNAAVEAAGEMPGVERIVHS
Rv3173c|M.tuberculosis_H37Rv NATPRERLLALFDRPNR---GDGRMRGCPFHNAAVEAAGEMPGVERIVHS
MAV_2097|M.avium_104 NRSPRARLLALFDTPAP---GDALMRGCPFHNAAVEAGQTMPEVRSIVRE
MMAR_2062|M.marinum_M GNTPEEQLLAIFDVLHEWFQSRDGYEGCSFINVLLELGADHPAGRACIG-
MUL_2793|M.ulcerans_Agy99 AAGGGQPLVAFADSWKQTLRASDYAAGCPIVAAALGRTES-PSAADVAGE
Mflv_2228|M.gilvum_PYR-GCK D-DPRERLIEGMLSSLRNVRESPALS-SWFATTQRPIGAEMAEQSEVIKA
:: .
MSMEG_4517|M.smegmatis_MC2_155 HRAWLRSTLAGLLKQAGVGS---PVALARRIQLLYDGALLGSKLERS-TK
MAB_2458c|M.abscessus_ATCC_199 HREWFRATVAALLREAGLAR---PDSIARQVQLLYDGALTGSKIDKS-VV
TH_3775|M.thermoresistible__bu HKTAVRDYLA--DLVAAAEL---PSELAEQLAILADGAIVAATIWGDGTD
Mvan_4792|M.vanbaalenii_PYR-1 HKAKLTQFLVRQARLAGVAA---PDDLAEQLTVLHTGAADYALLYGHYPD
Mb3198c|M.bovis_AF2122/97 HKRDYIKGLARLAREAGAAH---PRSLGNQLAVLFEGAAALSTSLDD-AG
Rv3173c|M.tuberculosis_H37Rv HKRDYIKGLARLAREAGAAH---PRSLGNQLAVLFEGAAALSTSLDD-AG
MAV_2097|M.avium_104 HKRTYIDGLAELARRAGASD---PQLLGNQLAVLYEGAAALSTSLND-PS
MMAR_2062|M.marinum_M HIDHVRGIVRERAVAAGLHD---VEDFAWSWHILMKGAIILAAVGDP--D
MUL_2793|M.ulcerans_Agy99 VFGAWQTVLAGRFRAQGVGDDT-AESLATTVVAAVEGAVILCLAARS-TD
Mflv_2228|M.gilvum_PYR-GCK LTEAFVISLGPDDADARASGATGEGSVAHRSRWLVRVMTSLMLFPGHDEA
: ..
MSMEG_4517|M.smegmatis_MC2_155 PITAARDLVEELIELGRR-------
MAB_2458c|M.abscessus_ATCC_199 PITLARRLTRQLIG-----------
TH_3775|M.thermoresistible__bu AAAAARRAAATLISAS---------
Mvan_4792|M.vanbaalenii_PYR-1 STRTAVAALLTAAGL----------
Mb3198c|M.bovis_AF2122/97 PWAHARAAAEVLIDQATARPV----
Rv3173c|M.tuberculosis_H37Rv PWAHARAAAEVLIDQATARPV----
MAV_2097|M.avium_104 PWAHARAAAHTLIDRAVSRDDGD--
MMAR_2062|M.marinum_M SARRAQRMAQVLIEQHRAAGAAAC-
MUL_2793|M.ulcerans_Agy99 PLDRTVPMLQQLIAQHTSRPSG---
Mflv_2228|M.gilvum_PYR-GCK DERAMLEEFVVPIVLPRRQADQATQ