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SDTTAERRGGRGARERLLSSASRLFYRNGIHATGVEALIQHANVSKRTLYQHFSSKNELVEHYLRRIDGA GGSPMEKPLLNQELPPRDRLLAIFDAVPVARFRGCPFHNAAVESAGELSAVEDIVRDHKRRFAELLVQVA TEAGAADPYALGPQLLVLFEGAAALATSLNDTGAFVHARAAAAQLIDCAVRGQIGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2153 | - | - | 100% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6503 | - | 9e-27 | 38.80% (183) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6244 | - | 4e-18 | 33.70% (181) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3198c | - | 4e-52 | 58.20% (189) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4672 | - | 1e-08 | 46.97% (66) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3173c | - | 4e-52 | 58.20% (189) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-07 | 43.28% (67) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2458c | - | 2e-16 | 31.28% (179) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2062 | - | 3e-12 | 30.39% (181) | hypothetical protein MMAR_2062 |
| M. avium 104 | MAV_2097 | - | 5e-51 | 58.15% (184) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3775 | - | 2e-19 | 35.36% (181) | PUTATIVE TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_2529 | - | 2e-07 | 44.78% (67) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4792 | - | 3e-19 | 37.97% (158) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3198c|M.bovis_AF2122/97 ----------------------MPPVTRTTEPPRRGGRGARQRILKAAAE
Rv3173c|M.tuberculosis_H37Rv ----------------------MPPVTRTTEPPRRGGRGARQRILKAAAE
MAV_2097|M.avium_104 ----------------------MSKRRDVKHVTTGGGRGARRRILDTATE
MSMEG_2153|M.smegmatis_MC2_155 ----------------------MSDTT----AERRGGRGARERLLSSASR
TH_3775|M.thermoresistible__bu ----------------------------------MAETDDKNRVLATATT
Mvan_4792|M.vanbaalenii_PYR-1 ----------------------------------MPAEDPRQRAIDAAVE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MUL_2529|M.ulcerans_Agy99 MSDLAKAAQHRAVRSADRVR-STEGATPKARGNRLPRDERRGQLLIVASD
Mflv_4672|M.gilvum_PYR-GCK MSELAKTAPRRGGQPANGTG-SSGAAR---RGNRLPRDERRGQLLAAASE
MAB_2458c|M.abscessus_ATCC_199 -------------------MSSATVPTAADSARTARVLGPADRLLQTATD
MMAR_2062|M.marinum_M ---------------------------MAIPEATTAAVPARERILGAAYD
: : *
Mb3198c|M.bovis_AF2122/97 LFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE
Rv3173c|M.tuberculosis_H37Rv LFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE
MAV_2097|M.avium_104 LFYRDGINATGVERLAAEASVSKRTLYQHFPSKNAVVEEYLRGIQQAVGD
MSMEG_2153|M.smegmatis_MC2_155 LFYRNGIHATGVEALIQHANVSKRTLYQHFSSKNELVEHYLRRIDGAGGS
TH_3775|M.thermoresistible__bu LFNERGVQAVGMDAIRDAAGISLKRLYSCFRSKADLVAAVLEQRDADVRR
Mvan_4792|M.vanbaalenii_PYR-1 LFHREGFGAVGIDRLTTSIGMSKRTLYKYFDSKDDLLLAVLDSCEGMALR
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
MUL_2529|M.ulcerans_Agy99 VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLNRHVDKLVA
Mflv_4672|M.gilvum_PYR-GCK VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKVELYLAVLQRHVDNLVS
MAB_2458c|M.abscessus_ATCC_199 LFATQGIRSVGIDQILREAGVAKASLYSSFGSKDALVVAYLEELDQRDRN
MMAR_2062|M.marinum_M LFSRRGIRAVGTDEVIERAGVARATLYRHFATKDDLVLAVLQRREELWTF
:* * :.* : : .:: ** * :* : *
Mb3198c|M.bovis_AF2122/97 -ADK-MPKASNATPRERLLALFDRPNR---GDGRMRGCPFHNAAVEAAGE
Rv3173c|M.tuberculosis_H37Rv -ADK-MPKASNATPRERLLALFDRPNR---GDGRMRGCPFHNAAVEAAGE
MAV_2097|M.avium_104 -PIHPEADATNRSPRARLLALFDTPAP---GDALMRGCPFHNAAVEAGQT
MSMEG_2153|M.smegmatis_MC2_155 -PMEKPLLNQELPPRDRLLAIFDAVP-----VARFRGCPFHNAAVESAGE
TH_3775|M.thermoresistible__bu -AMTEYVQSRAADPRDRILAVFDFLAHWF-AESDFRGCMFINTIGELGGT
Mvan_4792|M.vanbaalenii_PYR-1 -DLPD--EDDDSSPRDRILAVFDAQAKYC-TDPDFAGCFFVNIATEFRDP
MLBr_00815|M.leprae_Br4923 -SVQQALRTTTNNRQRLHAAVQAFFDFIE-HDGQGYRLIFENDNITEPRV
MUL_2529|M.ulcerans_Agy99 -GVQQALRTTTDNRGRLYAAVQAFFDFIE-HDSQGYRLIFENDYVTEPEV
Mflv_4672|M.gilvum_PYR-GCK -GVRQALRTTTDNRQRVRAAVQAFFDFIE-HDSQGYRLIFENDYVTEPQV
MAB_2458c|M.abscessus_ATCC_199 -RWNAAVAAQR-DPIAKVLTFFDLAATAA-ESRNFRGCLYANAATEFPG-
MMAR_2062|M.marinum_M GLIEQKSRARGNTPEEQLLAIFDVLHEWFQSRDGYEGCSFINVLLELGAD
:. : *
Mb3198c|M.bovis_AF2122/97 MPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALST
Rv3173c|M.tuberculosis_H37Rv MPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALST
MAV_2097|M.avium_104 MPEVRSIVREHKRTYIDGLAELARRAGASDPQLLGNQLAVLYEGAAALST
MSMEG_2153|M.smegmatis_MC2_155 LSAVEDIVRDHKRRFAELLVQVATEAGAADPYALGPQLLVLFEGAAALAT
TH_3775|M.thermoresistible__bu STDVRRIARLHKTAVRDYLA--DLVAAAELPSELAEQLAILADGAIVAAT
Mvan_4792|M.vanbaalenii_PYR-1 DHRAVRIAADHKAKLTQFLVRQARLAGVAAPDDLAEQLTVLHTGAADYAL
MLBr_00815|M.leprae_Br4923 AAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLD
MUL_2529|M.ulcerans_Agy99 AAQVRVATESCIDAVFALISADSGLDPHRARMIAVALVSMSVDCARYWLD
Mflv_4672|M.gilvum_PYR-GCK AAQVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLVSISVDSARYWLN
MAB_2458c|M.abscessus_ATCC_199 --LQLEPVRTHREWFRATVAALLREAGLARPDSIARQVQLLYDGALTGSK
MMAR_2062|M.marinum_M HPAGRACIG-HIDHVRGIVRERAVAAGLHDVEDFAWSWHILMKGAIILAA
: : *
Mb3198c|M.bovis_AF2122/97 SLDDAGPWAHARAAAEVLIDQATARPV---
Rv3173c|M.tuberculosis_H37Rv SLDDAGPWAHARAAAEVLIDQATARPV---
MAV_2097|M.avium_104 SLNDPSPWAHARAAAHTLIDRAVSRDDGD-
MSMEG_2153|M.smegmatis_MC2_155 SLNDTGAFVHARAAAAQLIDCAVRGQIGR-
TH_3775|M.thermoresistible__bu IWGDGTDAAAAARRAAATLISAS-------
Mvan_4792|M.vanbaalenii_PYR-1 LYGHYPDSTRTAVAALLTAAGL--------
MLBr_00815|M.leprae_Br4923 TNRPISKSDAVEGTVQFAWGGLSHVPLTRL
MUL_2529|M.ulcerans_Agy99 SDRPISKSDAIEGTVQFAWGGLSHVPLARS
Mflv_4672|M.gilvum_PYR-GCK NERPIDKDDAVEGTVQFIWGGLSHVPLTRS
MAB_2458c|M.abscessus_ATCC_199 IDKSVVPITLARRLTRQLIG----------
MMAR_2062|M.marinum_M VGDPDSARRAQRMAQVLIEQHRAAGAAAC-