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SSATVPTAADSARTARVLGPADRLLQTATDLFATQGIRSVGIDQILREAGVAKASLYSSFGSKDALVVAY LEELDQRDRNRWNAAVAAQRDPIAKVLTFFDLAATAAESRNFRGCLYANAATEFPGLQLEPVRTHREWFR ATVAALLREAGLARPDSIARQVQLLYDGALTGSKIDKSVVPITLARRLTRQLIG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2458c | - | - | 100% (195) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3924c | - | 1e-10 | 27.37% (179) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4360c | - | 3e-07 | 27.78% (162) | transcriptional regulator TetR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3198c | - | 5e-18 | 34.08% (179) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0142 | - | 2e-10 | 34.39% (157) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3173c | - | 5e-18 | 34.08% (179) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 1e-06 | 41.10% (73) | putative TetR/AcrR-family transcriptional regulator |
| M. marinum M | MMAR_2062 | - | 8e-14 | 32.39% (176) | hypothetical protein MMAR_2062 |
| M. avium 104 | MAV_2097 | - | 3e-18 | 34.64% (179) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4517 | - | 2e-65 | 62.89% (194) | TetR-type transcriptional regulator of sulfur metabolism |
| M. thermoresistible (build 8) | TH_3775 | - | 1e-17 | 35.44% (158) | PUTATIVE TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4487 | - | 1e-06 | 24.48% (143) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4792 | - | 4e-15 | 32.03% (153) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2458c|M.abscessus_ATCC_199 ---------MSSATVPTAADSARTARVLGPADRLLQTATDLFATQGIRSV
MSMEG_4517|M.smegmatis_MC2_155 MPFSGYPVAMSTTRPAIAPKSAHQAVSLPPAQRLLNTASELFAGQGIRAV
Mb3198c|M.bovis_AF2122/97 ------------MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINAT
Rv3173c|M.tuberculosis_H37Rv ------------MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINAT
MAV_2097|M.avium_104 ------------MSKRRDVKHVTTGGGRGARRRILDTATELFYRDGINAT
TH_3775|M.thermoresistible__bu ------------------------MAETDDKNRVLATATTLFNERGVQAV
Mvan_4792|M.vanbaalenii_PYR-1 ------------------------MPAEDPRQRAIDAAVELFHREGFGAV
Mflv_0142|M.gilvum_PYR-GCK ------------------MTRPLRADAARNRARVLEVAYDTFAAEGLTVP
MLBr_00316|M.leprae_Br4923 ----MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLSVP
MMAR_2062|M.marinum_M -----------------MAIPEATTAAVPARERILGAAYDLFSRRGIRAV
MUL_4487|M.ulcerans_Agy99 ---------------MGRTDWLAAHRSEVAADRILDAAERLYTEHDPASI
* : .* : .
MAB_2458c|M.abscessus_ATCC_199 GIDQILREAGVAKASLYSSFGSKDALVVAYLEELDQRDRNRWN--AAVAA
MSMEG_4517|M.smegmatis_MC2_155 GIDLILREAGVAKASLYSTYGSKDALVIAYLTNLDHADRNRWE--QTVAG
Mb3198c|M.bovis_AF2122/97 GVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADK--MPKAS
Rv3173c|M.tuberculosis_H37Rv GVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADK--MPKAS
MAV_2097|M.avium_104 GVERLAAEASVSKRTLYQHFPSKNAVVEEYLRGIQQAVGDPIHP-EADAT
TH_3775|M.thermoresistible__bu GMDAIRDAAGISLKRLYSCFRSKADLVAAVLEQRDADVRRAMTE-YVQSR
Mvan_4792|M.vanbaalenii_PYR-1 GIDRLTTSIGMSKRTLYKYFDSKDDLLLAVLDSCEGMALRDLPD---EDD
Mflv_0142|M.gilvum_PYR-GCK -IDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVRRIAERAR---TLLA
MLBr_00316|M.leprae_Br4923 -IDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGY---VLLK
MMAR_2062|M.marinum_M GTDEVIERAGVARATLYRHFATKDDLVLAVLQRREELWTFGLIEQKSRAR
MUL_4487|M.ulcerans_Agy99 GMNEIARAAGCSRATLYRYFESREALRTAYVHRETLRLGREIMQ--QIGD
: : . . :* : :: :
MAB_2458c|M.abscessus_ATCC_199 QRDPIAKVLTFFDLAATA--AESRNFRGCLYANAATEFPGLQLEP---VR
MSMEG_4517|M.smegmatis_MC2_155 VEDPVQRVLTFFDLASRN--AARRDFRGCLYANAATEYPGVELEP---VR
Mb3198c|M.bovis_AF2122/97 NATPRERLLALFDRPNRG--DGR--MRGCPFHNAAVEAAGEMPGVERIVH
Rv3173c|M.tuberculosis_H37Rv NATPRERLLALFDRPNRG--DGR--MRGCPFHNAAVEAAGEMPGVERIVH
MAV_2097|M.avium_104 NRSPRARLLALFDTPAPG--DAL--MRGCPFHNAAVEAGQTMPEVRSIVR
TH_3775|M.thermoresistible__bu AADPRDRILAVFDFLAHW--FAESDFRGCMFINTIGELGGTSTDVRRIAR
Mvan_4792|M.vanbaalenii_PYR-1 DSSPRDRILAVFDAQAKY--CTDPDFAGCFFVNIATEFRDPDHRAVRIAA
Mflv_0142|M.gilvum_PYR-GCK VEGPGQALFVFFRDMVRS-AAVDHGLVDALMNQG-LDLEAVAPGV----E
MLBr_00316|M.leprae_Br4923 SAGPGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAPDA----E
MMAR_2062|M.marinum_M GNTPEEQLLAIFDVLHEW-FQSRDGYEGCSFINVLLELGADHPAG-RACI
MUL_4487|M.ulcerans_Agy99 IDDPRDQLITSITATLRM--VRQRPALAAWFASTRPPIGGELAGQSEVIA
* ::. : .
MAB_2458c|M.abscessus_ATCC_199 THREWFRATVAALLREAGLARPDSIARQVQLLYDGALTGSKIDKSVVPIT
MSMEG_4517|M.smegmatis_MC2_155 AHRAWLRSTLAGLLKQAGVGSPVALARRIQLLYDGALLGSKLERSTKPIT
Mb3198c|M.bovis_AF2122/97 SHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWA
Rv3173c|M.tuberculosis_H37Rv SHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWA
MAV_2097|M.avium_104 EHKRTYIDGLAELARRAGASDPQLLGNQLAVLYEGAAALSTSLNDPSPWA
TH_3775|M.thermoresistible__bu LHKTAVRDYLA--DLVAAAELPSELAEQLAILADGAIVAATIWGDGTDAA
Mvan_4792|M.vanbaalenii_PYR-1 DHKAKLTQFLVRQARLAGVAAPDDLAEQLTVLHTGAADYALLYGHYPDST
Mflv_0142|M.gilvum_PYR-GCK AAFLSTLGDLLSAAQGAGTVRPDVDVAVVKALLVVCKVPQVFDSEVTERV
MLBr_00316|M.leprae_Br4923 DAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYNSALAERV
MMAR_2062|M.marinum_M GHIDHVRGIVRERAVAAGLHDVEDFAWSWHILMKGAIILAAVGDPDSARR
MUL_4487|M.ulcerans_Agy99 GLAAAFLQSLGPEAPAAVERRARWTVRVIVSLLMFPGQDEADERAMLEEF
: * :
MAB_2458c|M.abscessus_ATCC_199 LARRLTRQLIG---------
MSMEG_4517|M.smegmatis_MC2_155 AARDLVEELIELGRR-----
Mb3198c|M.bovis_AF2122/97 HARAAAEVLIDQATARPV--
Rv3173c|M.tuberculosis_H37Rv HARAAAEVLIDQATARPV--
MAV_2097|M.avium_104 HARAAAHTLIDRAVSRDDGD
TH_3775|M.thermoresistible__bu AAARRAAATLISAS------
Mvan_4792|M.vanbaalenii_PYR-1 RTAVAALLTAAGL-------
Mflv_0142|M.gilvum_PYR-GCK TRVIEDGLRPLR--------
MLBr_00316|M.leprae_Br4923 TDVVVDGLRAAR--------
MMAR_2062|M.marinum_M AQRMAQVLIEQHRAAGAAAC
MUL_4487|M.ulcerans_Agy99 VAPVVTPFPTRR--------