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TARERLIESAIELLRRNGVAGTGLADLLEHSGTARRSVYVNFPGGKSELMTEATRTAGRLMDSTLASIAA GGGQPLVAFADSWKQTLRASDYAAGCPIVAAALGRTESPSAADVAGEVFGAWQTVLAGRFRAQGVGDDTA ESLATTVVAAVEGAVILCLAARSTDPLDRTVPMLQQLIAQHTSRPSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2793 | - | - | 100% (188) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_1119 | - | 3e-29 | 37.64% (178) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_1086 | - | 1e-23 | 33.93% (168) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0202 | - | 3e-26 | 35.71% (182) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3287 | - | 3e-23 | 35.11% (188) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0196 | - | 3e-26 | 35.71% (182) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4634c | - | 9e-42 | 48.63% (183) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3560 | - | 1e-101 | 98.94% (188) | transcriptional regulatory protein |
| M. avium 104 | MAV_4985 | - | 3e-28 | 37.57% (181) | regulatory protein, TetR |
| M. smegmatis MC2 155 | MSMEG_3520 | - | 9e-23 | 35.11% (188) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3160 | - | 4e-28 | 39.89% (178) | PUTATIVE putative regulatory protein, TetR |
| M. vanbaalenii PYR-1 | Mvan_0275 | - | 6e-32 | 41.08% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0202|M.bovis_AF2122/97 -----------MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
Rv0196|M.tuberculosis_H37Rv -----------MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGS
MAV_4985|M.avium_104 -----------MRSPREKMVVSAALLIRERGAHATAISDVLEHSGAPRGS
Mflv_3287|M.gilvum_PYR-GCK -----------MTTPRERMVVSAALLIRERGAHPTAIADVLQHSGAPRGS
MSMEG_3520|M.smegmatis_MC2_155 -----------MASPRERMVRSAAVLIRERGAHPTAIADVLAHSGAPRGS
Mvan_0275|M.vanbaalenii_PYR-1 -------MSPRTSDARERMLDSASTLIREHGASGTSLDDILRHSRAPRGS
TH_3160|M.thermoresistible__bu MGVEVTRRRDPQSGPRAAMLRSAVALMRRQGVAATSFADVLADSGAPRGS
MUL_2793|M.ulcerans_Agy99 ------------MTARERLIESAIELLRRNGVAGTGLADLLEHSGTARRS
MMAR_3560|M.marinum_M ------------MTARERLIESAIELLRRNGVAGTGLADLLEHSGTARRS
MAB_4634c|M.abscessus_ATCC_199 ------------MSARDTLIASVTGLVRRRGVAGTGLNALLEDSGVSRRT
.* :: *. *:*..*. *.: :* .* ..* :
Mb0202|M.bovis_AF2122/97 AYHYFPGGRTQLLCEAVDYAGEHVAAMINEAEGG----LELLDALIDKYR
Rv0196|M.tuberculosis_H37Rv AYHYFPGGRTQLLCEAVDYAGEHVAAMINEAEGG----LELLDALIDKYR
MAV_4985|M.avium_104 AYHYFPGGRTQLLCEAVDFAGEYVAAVIAGAESG----ARLLDTLIDTYR
Mflv_3287|M.gilvum_PYR-GCK AYHYFPGGRTQLLCEAVDYAAEFMAERLSRASSS----LRVLDDLFGYYR
MSMEG_3520|M.smegmatis_MC2_155 AYHYFPGGRTQLLCEAIDYASDHVTARLDRATDT----FALLDDMVARFR
Mvan_0275|M.vanbaalenii_PYR-1 VYHHFPGGRAQLIEEVVDRAGGALAAILGDAGDATP--ATTFDVFISTWK
TH_3160|M.thermoresistible__bu IYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAADLPTALRELVGVWR
MUL_2793|M.ulcerans_Agy99 VYVNFPGGKSELMTEATRTAGRLMDSTLASIAAGG-GQP--LVAFADSWK
MMAR_3560|M.marinum_M VYVNFPGGKSELMTEATRTAGRLMDSTLASIAAGG-DQP--LVAFADSWK
MAB_4634c|M.abscessus_ATCC_199 IYLNFPGGKQELVAEATRLAGNELTAIIKAAGDDV-DPARGIQLFIELWK
* **.*: :*: *. *. : : : : ::
Mb0202|M.bovis_AF2122/97 QQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTAQ
Rv0196|M.tuberculosis_H37Rv QQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAAVFDRWSDLTAQ
MAV_4985|M.avium_104 EQLRDSDFRAGCPVVAVAVEAGEQSDAER--PVIERAAAAFDRWTDLIAQ
Mflv_3287|M.gilvum_PYR-GCK TQLQDSDFRAGCPVVAVAVESGDPDKPEQSAPVIERAAAALTRWSDIIEQ
MSMEG_3520|M.smegmatis_MC2_155 DQLLASDFRAGCPVVAVAVEAGDPEKADSADAVRERAGAAFQRWIARITA
Mvan_0275|M.vanbaalenii_PYR-1 AGLEASGFRAGCPVLAVAVETNDD-----APQLTEAAARAFGSWRDALNT
TH_3160|M.thermoresistible__bu DGLEAGDYAVGCPIVAAALG--------TERAARDVAGVAFADLTGLISD
MUL_2793|M.ulcerans_Agy99 QTLRASDYAAGCPIVAAALGRTES------PSAADVAGEVFGAWQTVLAG
MMAR_3560|M.marinum_M QTLRASDYAAGCPIVAAALGRTES------PSAADAAGEVFGAWQTVLAG
MAB_4634c|M.abscessus_ATCC_199 AQLAETEMQAGCPVVAAVLGRTEA------PEAAAVAADAFESWQKILID
* .***: *. : *. .:
Mb0202|M.bovis_AF2122/97 RFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNLL
Rv0196|M.tuberculosis_H37Rv RFIADGIPPDRAHELAVLATSTLEGAILLARVRRDLTPLDLVHRQLRNLL
MAV_4985|M.avium_104 RFIADGIRRRRAAELAVLATSALEGAIVLARARRDPAPLDVVHRQLRDLL
Mflv_3287|M.gilvum_PYR-GCK RLIADGVPRADAAALAMLVLTSFEGAIVVARATRDLKPLDLVAGQLASLI
MSMEG_3520|M.smegmatis_MC2_155 RLCDDGVPVERAEELATLITTSVEGAVLVARTTRDVKPLELVHRQLREQL
Mvan_0275|M.vanbaalenii_PYR-1 VLRHQGVPPARARRLATLIVAAVEGAVALSRVERNTQPIDDVARELRALI
TH_3160|M.thermoresistible__bu KLVSDGMARRRANSVAVLILTAMEGALVLAQARRDPAALDAVVDELTLLC
MUL_2793|M.ulcerans_Agy99 RFRAQGVGDDTAESLATTVVAAVEGAVILCLAARSTDPLDRT---VPMLQ
MMAR_3560|M.marinum_M RFRAQGVGDDTAESLATTVVAAVEGAVILCLAARSTDPLDRT---VPMLQ
MAB_4634c|M.abscessus_ATCC_199 RLVRYDVDGETARSLASTMIAAIEGAVIMSIAAQSTEALDDVGQRLVELV
: .: * :* ::.***: :. . :. .:: . :
Mb0202|M.bovis_AF2122/97 LAELP------ERSR---
Rv0196|M.tuberculosis_H37Rv LAELP------ERSR---
MAV_4985|M.avium_104 AAELAGETAAGRKSRHDR
Mflv_3287|M.gilvum_PYR-GCK DARTV------TRRK---
MSMEG_3520|M.smegmatis_MC2_155 TAATG------KKDRP--
Mvan_0275|M.vanbaalenii_PYR-1 RQATD-------AS----
TH_3160|M.thermoresistible__bu SGSAD-------------
MUL_2793|M.ulcerans_Agy99 QLIAQHTSRPSG------
MMAR_3560|M.marinum_M QLIAQHTSRPSG------
MAB_4634c|M.abscessus_ATCC_199 QLYVPADAKPKPHVD---