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MLDPDAARERVLAAAEELFYARGIQAVGMDAVRTASGVSLKRLYQMFPSKEDLVVSFLQQRDSRWLGRLT AAVEAHSDPRERIPAVFDWLYSWFSEPDYRGCAFINSFGELGGISPAVADQARHHKREFHAYLTELVGAA GYPAELAAHLALLAEGAIVNSAIFGTPDPATRAKQAALTLMQASGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6244 | - | - | 100% (186) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2153 | - | 4e-18 | 33.70% (181) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4517 | - | 9e-18 | 30.68% (176) | TetR-type transcriptional regulator of sulfur metabolism |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3198c | - | 5e-20 | 36.96% (184) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4672 | - | 3e-10 | 35.58% (104) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3173c | - | 5e-20 | 36.96% (184) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 3e-08 | 30.33% (122) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2458c | - | 5e-20 | 32.57% (175) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2062 | - | 1e-23 | 39.23% (181) | hypothetical protein MMAR_2062 |
| M. avium 104 | MAV_3517 | - | 3e-23 | 40.00% (195) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3775 | - | 7e-45 | 54.19% (179) | PUTATIVE TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_2529 | - | 5e-08 | 31.97% (122) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4792 | - | 9e-20 | 34.68% (173) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3198c|M.bovis_AF2122/97 ----------------------MPPVTRTTEPPRRGGRGARQRILKAAAE
Rv3173c|M.tuberculosis_H37Rv ----------------------MPPVTRTTEPPRRGGRGARQRILKAAAE
MSMEG_6244|M.smegmatis_MC2_155 ---------------------------MLDPDAA------RERVLAAAEE
TH_3775|M.thermoresistible__bu ---------------------------MAETDD-------KNRVLATATT
MMAR_2062|M.marinum_M ---------------------------MAIPEATTAAVPARERILGAAYD
MAV_3517|M.avium_104 ---------------------------MTTPDAGSSGASARERVLTAAYE
Mvan_4792|M.vanbaalenii_PYR-1 ---------------------------MPAEDP-------RQRAIDAAVE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MUL_2529|M.ulcerans_Agy99 MSDLAKAAQHRAVRSADRVR-STEGATPKARGNRLPRDERRGQLLIVASD
Mflv_4672|M.gilvum_PYR-GCK MSELAKTAPRRGGQPANGTG-SSGAAR---RGNRLPRDERRGQLLAAASE
MAB_2458c|M.abscessus_ATCC_199 -------------------MSSATVPTAADSARTARVLGPADRLLQTATD
: : .*
Mb3198c|M.bovis_AF2122/97 LFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRG--LRQAA
Rv3173c|M.tuberculosis_H37Rv LFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRG--LRQAA
MSMEG_6244|M.smegmatis_MC2_155 LFYARGIQAVGMDAVRTASGVSLKRLYQMFPSKEDLVVSFLQQRDSRWLG
TH_3775|M.thermoresistible__bu LFNERGVQAVGMDAIRDAAGISLKRLYSCFRSKADLVAAVLEQRDADVRR
MMAR_2062|M.marinum_M LFSRRGIRAVGTDEVIERAGVARATLYRHFATKDDLVLAVLQRREELWTF
MAV_3517|M.avium_104 LFSRRGIRAVGTDEVIARAGVARATLYRHFATKNDLVLAVLQRREELWTY
Mvan_4792|M.vanbaalenii_PYR-1 LFHREGFGAVGIDRLTTSIGMSKRTLYKYFDSKDDLLLAVLDSCEGMALR
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
MUL_2529|M.ulcerans_Agy99 VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLNRHVDKLVA
Mflv_4672|M.gilvum_PYR-GCK VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKVELYLAVLQRHVDNLVS
MAB_2458c|M.abscessus_ATCC_199 LFATQGIRSVGIDQILREAGVAKASLYSSFGSKDALVVAYLEELDQRDRN
:* .* :.* : : .:: ** * :* * *
Mb3198c|M.bovis_AF2122/97 GEADKMPKASNATPRERLLALFDRPN---RGDGRMRGCPFHNAAVEAAGE
Rv3173c|M.tuberculosis_H37Rv GEADKMPKASNATPRERLLALFDRPN---RGDGRMRGCPFHNAAVEAAGE
MSMEG_6244|M.smegmatis_MC2_155 -RLTAAVEAHS-DPRERIPAVFDWLYSWFSEPD-YRGCAFINSFGELGGI
TH_3775|M.thermoresistible__bu -AMTEYVQSRAADPRDRILAVFDFLAHWFAESD-FRGCMFINTIGELGGT
MMAR_2062|M.marinum_M GLIEQKSRARGNTPEEQLLAIFDVLHEWFQSRDGYEGCSFINVLLELG-A
MAV_3517|M.avium_104 GLIEEQSRLRGATPEEQLLAIFDVMDEWFRQGDRYEGCSFINVLLELG-P
Mvan_4792|M.vanbaalenii_PYR-1 DLPDED---DDSSPRDRILAVFDAQAKYCTDPD-FAGCFFVNIATEFRDP
MLBr_00815|M.leprae_Br4923 SVQQALR--TTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRV
MUL_2529|M.ulcerans_Agy99 GVQQALR--TTTDNRGRLYAAVQAFFDFIEHDSQGYRLIFENDYVTEPEV
Mflv_4672|M.gilvum_PYR-GCK GVRQALR--TTTDNRQRVRAAVQAFFDFIEHDSQGYRLIFENDYVTEPQV
MAB_2458c|M.abscessus_ATCC_199 RWNAAVA--AQRDPIAKVLTFFDLAATAAESRN-FRGCLYANAATEFPGL
:: : .: . : *
Mb3198c|M.bovis_AF2122/97 MPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALST
Rv3173c|M.tuberculosis_H37Rv MPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALST
MSMEG_6244|M.smegmatis_MC2_155 SPAVADQARHHKREFHAYLTELVGAAGYP--AELAAHLALLAEGAIVNSA
TH_3775|M.thermoresistible__bu STDVRRIARLHKTAVRDYLADLVAAAELP--SELAEQLAILADGAIVAAT
MMAR_2062|M.marinum_M DHPAGRACIGHIDHVRGIVRERAVAAGLHDVEDFAWSWHILMKGAIILAA
MAV_3517|M.avium_104 EHPAGKACIAHIDRVRDIVRRRAVAAGLTDVEDFASSWHILMKGAIVLAA
Mvan_4792|M.vanbaalenii_PYR-1 DHRAVRIAADHKAKLTQFLVRQARLAGVAAPDDLAEQLTVLHTGAADYAL
MLBr_00815|M.leprae_Br4923 AAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLD
MUL_2529|M.ulcerans_Agy99 AAQVRVATESCIDAVFALISADSGLDPHRARMIAVALVSMSVDCARYWLD
Mflv_4672|M.gilvum_PYR-GCK AAQVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLVSISVDSARYWLN
MAB_2458c|M.abscessus_ATCC_199 QLEP---VRTHREWFRATVAALLREAGLARPDSIARQVQLLYDGALTGSK
: : *
Mb3198c|M.bovis_AF2122/97 SLDD-AGPWAHARAAAEVLIDQATARPV--------
Rv3173c|M.tuberculosis_H37Rv SLDD-AGPWAHARAAAEVLIDQATARPV--------
MSMEG_6244|M.smegmatis_MC2_155 IFGT-PDPATRAKQAALTLMQASGG-----------
TH_3775|M.thermoresistible__bu IWGDGTDAAAAARRAAATLISAS-------------
MMAR_2062|M.marinum_M VGDP--DSARRAQRMAQVLIEQHR-----AAGAAAC
MAV_3517|M.avium_104 VGDL--DAARRARRMARTLIEEHRPPLVSDTGEAV-
Mvan_4792|M.vanbaalenii_PYR-1 LYGHYPDSTRTAVAALLTAAGL--------------
MLBr_00815|M.leprae_Br4923 TNRPISKSDAVEGTVQFAWGGLSHVPLTRL------
MUL_2529|M.ulcerans_Agy99 SDRPISKSDAIEGTVQFAWGGLSHVPLARS------
Mflv_4672|M.gilvum_PYR-GCK NERPIDKDDAVEGTVQFIWGGLSHVPLTRS------
MAB_2458c|M.abscessus_ATCC_199 IDKS-VVPITLARRLTRQLIG---------------