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M. thermoresistible (build 8) TH_3775 (-)

annotation: TetR-family protein transcriptional regulator
coordinates: 1741920 - 1742477
length: 186

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3775--100% (186)TetR-family protein transcriptional regulator
M. thermoresistible (build 8)TH_0452-1e-0839.56% (91) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. thermoresistible (build 8)TH_2839-1e-0525.30% (166) PUTATIVE transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3198c-7e-1635.33% (184) TetR/ACRR family transcriptional regulator
M. gilvum PYR-GCKMflv_0944-2e-0924.87% (193) TetR family transcriptional regulator
M. tuberculosis H37RvRv3173c-7e-1635.33% (184) TetR/ACRR family transcriptional regulator
M. leprae Br4923MLBr_00815-1e-0733.33% (90) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_2458c-1e-1735.44% (158) TetR family transcriptional regulator
M. marinum MMMAR_2062-9e-2036.67% (180) hypothetical protein MMAR_2062
M. avium 104MAV_3517-2e-2239.44% (180) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_6244-1e-4454.19% (179) TetR-family protein transcriptional regulator
M. ulcerans Agy99MUL_2529-9e-0836.67% (90) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_4792-9e-2336.81% (182) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb3198c|M.bovis_AF2122/97           ----------------------MPPVTRTTEPPRRGGRGARQRILKAAAE
Rv3173c|M.tuberculosis_H37Rv        ----------------------MPPVTRTTEPPRRGGRGARQRILKAAAE
TH_3775|M.thermoresistible__bu      ---------------------------MAETDD-------KNRVLATATT
MSMEG_6244|M.smegmatis_MC2_155      ---------------------------MLDPDAA------RERVLAAAEE
MMAR_2062|M.marinum_M               ---------------------------MAIPEATTAAVPARERILGAAYD
MAV_3517|M.avium_104                ---------------------------MTTPDAGSSGASARERVLTAAYE
Mvan_4792|M.vanbaalenii_PYR-1       ---------------------------MPAEDP-------RQRAIDAAVE
MLBr_00815|M.leprae_Br4923          MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MUL_2529|M.ulcerans_Agy99           MSDLAKAAQHRAVRSADRVR-STEGATPKARGNRLPRDERRGQLLIVASD
MAB_2458c|M.abscessus_ATCC_199      -------------------MSSATVPTAADSARTARVLGPADRLLQTATD
Mflv_0944|M.gilvum_PYR-GCK          ---------------------------MARPRTFD-----EDEVIEAGRD
                                                                              . : ..  

Mb3198c|M.bovis_AF2122/97           LFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRG--LRQAA
Rv3173c|M.tuberculosis_H37Rv        LFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRG--LRQAA
TH_3775|M.thermoresistible__bu      LFNERGVQAVGMDAIRDAAGISLKRLYSCFRSKADLVAAVLEQRDADVRR
MSMEG_6244|M.smegmatis_MC2_155      LFYARGIQAVGMDAVRTASGVSLKRLYQMFPSKEDLVVSFLQQRDSRWLG
MMAR_2062|M.marinum_M               LFSRRGIRAVGTDEVIERAGVARATLYRHFATKDDLVLAVLQRREELWTF
MAV_3517|M.avium_104                LFSRRGIRAVGTDEVIARAGVARATLYRHFATKNDLVLAVLQRREELWTY
Mvan_4792|M.vanbaalenii_PYR-1       LFHREGFGAVGIDRLTTSIGMSKRTLYKYFDSKDDLLLAVLDSCEGMALR
MLBr_00815|M.leprae_Br4923          VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
MUL_2529|M.ulcerans_Agy99           VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLNRHVDKLVA
MAB_2458c|M.abscessus_ATCC_199      LFATQGIRSVGIDQILREAGVAKASLYSSFGSKDALVVAYLEELDQRDRN
Mflv_0944|M.gilvum_PYR-GCK          LFWSQGYAATSIDDLSAATGLGRGSLYKAFGDKHSMFLRGLEQYCTEAIA
                                    :*  .*  :.. : :    .:.   **  *  *  :    *         

Mb3198c|M.bovis_AF2122/97           GEADKMPKASNATPRERLLALFDRPN---RGDGRMRGCPFHNAAVEAAGE
Rv3173c|M.tuberculosis_H37Rv        GEADKMPKASNATPRERLLALFDRPN---RGDGRMRGCPFHNAAVEAAGE
TH_3775|M.thermoresistible__bu      -AMTEYVQSRAADPRDRILAVFDFLAHWFAESD-FRGCMFINTIGELGGT
MSMEG_6244|M.smegmatis_MC2_155      -RLTAAVEAHS-DPRERIPAVFDWLYSWFSEPD-YRGCAFINSFGELGGI
MMAR_2062|M.marinum_M               GLIEQKSRARGNTPEEQLLAIFDVLHEWFQSRDGYEGCSFINVLLELG-A
MAV_3517|M.avium_104                GLIEEQSRLRGATPEEQLLAIFDVMDEWFRQGDRYEGCSFINVLLELG-P
Mvan_4792|M.vanbaalenii_PYR-1       DLPDED---DDSSPRDRILAVFDAQAKYCTDPD-FAGCFFVNIATEFRDP
MLBr_00815|M.leprae_Br4923          SVQQALR--TTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRV
MUL_2529|M.ulcerans_Agy99           GVQQALR--TTTDNRGRLYAAVQAFFDFIEHDSQGYRLIFENDYVTEPEV
MAB_2458c|M.abscessus_ATCC_199      RWNAAVA--AQRDPIAKVLTFFDLAATAAESRN-FRGCLYANAATEFPGL
Mflv_0944|M.gilvum_PYR-GCK          GIRAELRD-QDLSAYDRLVAHVRGRAADVVSDNDLRGCLLAKSAAELSST
                                                    :: : .          .        :        

Mb3198c|M.bovis_AF2122/97           MPGVERIVHSHKRDYIKGLAR---LAREAGAAHPRSLGNQLAVLFEGAAA
Rv3173c|M.tuberculosis_H37Rv        MPGVERIVHSHKRDYIKGLAR---LAREAGAAHPRSLGNQLAVLFEGAAA
TH_3775|M.thermoresistible__bu      STDVRRIARLHKTAVRDYLAD---LVAAAELP--SELAEQLAILADGAIV
MSMEG_6244|M.smegmatis_MC2_155      SPAVADQARHHKREFHAYLTE---LVGAAGYP--AELAAHLALLAEGAIV
MMAR_2062|M.marinum_M               DHPAGRACIGHIDHVRGIVRE---RAVAAGLHDVEDFAWSWHILMKGAII
MAV_3517|M.avium_104                EHPAGKACIAHIDRVRDIVRR---RAVAAGLTDVEDFASSWHILMKGAIV
Mvan_4792|M.vanbaalenii_PYR-1       DHRAVRIAADHKAKLTQFLVR---QARLAGVAAPDDLAEQLTVLHTGAAD
MLBr_00815|M.leprae_Br4923          AAQVRVATESCIDAVFALISA---DSRLDPHRARMVAVGLVGISVDCARY
MUL_2529|M.ulcerans_Agy99           AAQVRVATESCIDAVFALISA---DSGLDPHRARMIAVALVSMSVDCARY
MAB_2458c|M.abscessus_ATCC_199      QLEP---VRTHREWFRATVAA---LLREAGLARPDSIARQVQLLYDGALT
Mflv_0944|M.gilvum_PYR-GCK          DPEVARHVKRTLDAWLRELTATISAAQADGDIPSSTEAKALAALILAVLR
                                                      :                            .  

Mb3198c|M.bovis_AF2122/97           LSTSLDD-AGPWAHARAAAEVLIDQATARPV--------
Rv3173c|M.tuberculosis_H37Rv        LSTSLDD-AGPWAHARAAAEVLIDQATARPV--------
TH_3775|M.thermoresistible__bu      AATIWGDGTDAAAAARRAAATLISAS-------------
MSMEG_6244|M.smegmatis_MC2_155      NSAIFGT-PDPATRAKQAALTLMQASGG-----------
MMAR_2062|M.marinum_M               LAAVGDP--DSARRAQRMAQVLIEQHR-----AAGAAAC
MAV_3517|M.avium_104                LAAVGDL--DAARRARRMARTLIEEHRPPLVSDTGEAV-
Mvan_4792|M.vanbaalenii_PYR-1       YALLYGHYPDSTRTAVAALLTAAGL--------------
MLBr_00815|M.leprae_Br4923          WLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL------
MUL_2529|M.ulcerans_Agy99           WLDSDRPISKSDAIEGTVQFAWGGLSHVPLARS------
MAB_2458c|M.abscessus_ATCC_199      GSKIDKS-VVPITLARRLTRQLIG---------------
Mflv_0944|M.gilvum_PYR-GCK          GMEALRKGGASAATVKATAEQLVAML-------------
                                              .