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VPAEDPRQRAIDAAVELFHREGFGAVGIDRLTTSIGMSKRTLYKYFDSKDDLLLAVLDSCEGMALRDLPD EDDDSSPRDRILAVFDAQAKYCTDPDFAGCFFVNIATEFRDPDHRAVRIAADHKAKLTQFLVRQARLAGV AAPDDLAEQLTVLHTGAADYALLYGHYPDSTRTAVAALLTAAGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4792 | - | - | 100% (184) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5714 | - | 8e-08 | 28.40% (162) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0594 | - | 1e-07 | 26.28% (156) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3198c | - | 5e-19 | 39.35% (155) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0944 | - | 2e-08 | 30.00% (120) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3173c | - | 5e-19 | 39.35% (155) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 8e-06 | 26.87% (134) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2458c | - | 3e-15 | 32.03% (153) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2062 | - | 2e-17 | 33.71% (178) | hypothetical protein MMAR_2062 |
| M. avium 104 | MAV_1243 | - | 2e-20 | 35.84% (173) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6503 | - | 4e-20 | 35.91% (181) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3775 | - | 6e-23 | 36.81% (182) | PUTATIVE TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_3128 | - | 7e-06 | 30.67% (75) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3198c|M.bovis_AF2122/97 -MPPVTRTTEPPRRG--GRGARQRILKAAAELFYCEGINATGVELIANKA
Rv3173c|M.tuberculosis_H37Rv -MPPVTRTTEPPRRG--GRGARQRILKAAAELFYCEGINATGVELIANKA
MSMEG_6503|M.smegmatis_MC2_155 ----MTK----PR----GRGGRERIVAAAAALFEAQGITATTMEQIAAKA
MAV_1243|M.avium_104 -MDGVTELEKGPRGRRRGRGARERILGAAQQLFRERGINNTGMDLLCAAA
Mvan_4792|M.vanbaalenii_PYR-1 -MP--------------AEDPRQRAIDAAVELFHREGFGAVGIDRLTTSI
TH_3775|M.thermoresistible__bu ---------------MAETDDKNRVLATATTLFNERGVQAVGMDAIRDAA
MAB_2458c|M.abscessus_ATCC_199 MSSATVPTAADSARTARVLGPADRLLQTATDLFATQGIRSVGIDQILREA
MMAR_2062|M.marinum_M --------MAIPEATTAAVPARERILGAAYDLFSRRGIRAVGTDEVIERA
Mflv_0944|M.gilvum_PYR-GCK -------------MARPRTFDEDEVIEAGRDLFWSQGYAATSIDDLSAAT
MLBr_02568|M.leprae_Br4923 --------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEA
MUL_3128|M.ulcerans_Agy99 -----MPNDDWLVGGDRRRAAADRIYDAATDLIAHEGINQLDIDRLATLV
:. :. :: .* : :
Mb3198c|M.bovis_AF2122/97 SVSKRTLYQHFPSKSALVEEYLRGLRQAAGE-ADKMPKASNAT-PRERLL
Rv3173c|M.tuberculosis_H37Rv SVSKRTLYQHFPSKSALVEEYLRGLRQAAGE-ADKMPKASNAT-PRERLL
MSMEG_6503|M.smegmatis_MC2_155 PVSKRTLYAHFPTKDDLVVEFLQYVYRSGLT-VESALYDADVP-ARERIL
MAV_1243|M.avium_104 QVSKRTAYQHFGSKDELIAEYLR--RLDVDT-TSEVFERDDLT-PRERLL
Mvan_4792|M.vanbaalenii_PYR-1 GMSKRTLYKYFDSKDDLLLAVLDS-CEGMAL-RDLPDEDDDSS-PRDRIL
TH_3775|M.thermoresistible__bu GISLKRLYSCFRSKADLVAAVLEQRDADVRR-AMTEYVQSRAADPRDRIL
MAB_2458c|M.abscessus_ATCC_199 GVAKASLYSSFGSKDALVVAYLEELDQRDRN-RWNAAVAAQRD-PIAKVL
MMAR_2062|M.marinum_M GVARATLYRHFATKDDLVLAVLQRREELWTFGLIEQKSRARGNTPEEQLL
Mflv_0944|M.gilvum_PYR-GCK GLGRGSLYKAFGDKHSMFLRGLEQYCTEAIAGIRAELRDQDLS-AYDRLV
MLBr_02568|M.leprae_Br4923 QISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSP--KDLLR
MUL_3128|M.ulcerans_Agy99 HCSRATVYRYVGGKNDIRNVVVKRAAARIADSVRSAVENLSGR---ERVV
. * * : : :
Mb3198c|M.bovis_AF2122/97 ALFDRP-NRGDGR--MRGCPFHNAAVEAAGEMPGVERIVHSHKRDYIKGL
Rv3173c|M.tuberculosis_H37Rv ALFDRP-NRGDGR--MRGCPFHNAAVEAAGEMPGVERIVHSHKRDYIKGL
MSMEG_6503|M.smegmatis_MC2_155 AMFTVP-TRGDGP--VRGCPFVAAATEFPDPDSPAHAYTRERKQAFTLRI
MAV_1243|M.avium_104 AVFATPPAFTDEP--MPLCPFIAAAVEISDPQHPARVRAREYKTSVAARL
Mvan_4792|M.vanbaalenii_PYR-1 AVFDAQAKYCTDPD-FAGCFFVNIATEFRDPDHRAVRIAADHKAKLTQFL
TH_3775|M.thermoresistible__bu AVFDFLAHWFAESD-FRGCMFINTIGELGGTSTDVRRIARLHKTAVRDYL
MAB_2458c|M.abscessus_ATCC_199 TFFDLAATAAESRN-FRGCLYANAATEFPG---LQLEPVRTHREWFRATV
MMAR_2062|M.marinum_M AIFDVLHEWFQSRDGYEGCSFINVLLELGADHPAGRACIG-HIDHVRGIV
Mflv_0944|M.gilvum_PYR-GCK AHVRGRAADVVSDNDLRGCLLAKSAAELSSTDPEVARHVKRTLDAWLREL
MLBr_02568|M.leprae_Br4923 NTIVSFLRYIDANR--ASWIVMYIQAMSLPAFAQTVREARDQITELVAGL
MUL_3128|M.ulcerans_Agy99 AAIILSVQRIRADP--------LGQLMISSIHGGTQEVAWLADSPLLAGV
. :
Mb3198c|M.bovis_AF2122/97 ARLAREAGAAH---PRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAE
Rv3173c|M.tuberculosis_H37Rv ARLAREAGAAH---PRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAE
MSMEG_6503|M.smegmatis_MC2_155 AELLTELGADD---PHGLAEQLAILTDGVASRSMVFNDARRGDVGRAAAE
MAV_1243|M.avium_104 SETAREAGAAD---PELLGEQLALLLDGASVRTRALG-SDAFPTAAGIAA
Mvan_4792|M.vanbaalenii_PYR-1 VRQARLAGVAA---PDDLAEQLTVLHTGAADYALLYG--HYPDSTRTAVA
TH_3775|M.thermoresistible__bu ADLV--AAAEL---PSELAEQLAILADGAIVAATIWGDGTDAAAAARRAA
MAB_2458c|M.abscessus_ATCC_199 AALLREAGLAR---PDSIARQVQLLYDGALTGSKIDKSVVPITLARRLTR
MMAR_2062|M.marinum_M RERAVAAGLHD---VEDFAWSWHILMKGAIILAAVGDPDSARRAQRMAQV
Mflv_0944|M.gilvum_PYR-GCK TATISAAQADGDIPSSTEAKALAALILAVLRGMEALRKGGASAATVKATA
MLBr_02568|M.leprae_Br4923 MRVGTRSSRPD---HEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMI
MUL_3128|M.ulcerans_Agy99 ASDLTGLAGGD-----PHAARWVVRVVLSLMYWPAESEDVERLMVEKFVA
Mb3198c|M.bovis_AF2122/97 VLIDQATARPV------------
Rv3173c|M.tuberculosis_H37Rv VLIDQATARPV------------
MSMEG_6503|M.smegmatis_MC2_155 ALLTAAGL---------------
MAV_1243|M.avium_104 ALVERAIPPTAR-----------
Mvan_4792|M.vanbaalenii_PYR-1 ALLTAAGL---------------
TH_3775|M.thermoresistible__bu ATLISAS----------------
MAB_2458c|M.abscessus_ATCC_199 QLIG-------------------
MMAR_2062|M.marinum_M LIEQHRAAGAAAC----------
Mflv_0944|M.gilvum_PYR-GCK EQLVAML----------------
MLBr_02568|M.leprae_Br4923 NLFWHGLKGAPADRDFGPSIVAG
MUL_3128|M.ulcerans_Agy99 PVFAE------------------