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MNITPTTTTPATVRGNGRIALITGASRGIGAASAALFGQRGYRVAVHHEHNAIEAHHVADAINDHGGDAL VVQADLTRAEDVAEMTDAITHHWGPVEVLIHDGRRPYERTSFAALSIDRLEHAVAQELRAAFLVTKAVIP AMIAGDYGRLVYLSVAHSRLPQDKRIVEGTAKAALDQFVRYLAQELAPHGIPANLVAPGNVAGVDAGREA WTDDELWVLGTANTPARLVLPGDVARTVEFFASDDCVITTGHYAPVNAGLAVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4055 | - | - | 100% (263) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_2029 | - | 4e-26 | 33.74% (246) | 3-ketoacyl-ACP/CoA redutase |
| M. smegmatis MC2 155 | MSMEG_3262 | - | 3e-19 | 30.00% (250) | L-xylulose reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1519 | fabG1 | 2e-18 | 26.05% (261) | 3-oxoacyl- |
| M. gilvum PYR-GCK | Mflv_1258 | - | 2e-19 | 28.86% (246) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1483 | fabG1 | 2e-18 | 26.05% (261) | 3-oxoacyl- |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-15 | 27.17% (265) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_2032 | - | 5e-20 | 27.49% (251) | 3-oxoacyl- |
| M. marinum M | MMAR_2592 | - | 3e-22 | 29.41% (255) | short chain dehydrogenase |
| M. avium 104 | MAV_3012 | - | 4e-22 | 30.74% (244) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_2552 | - | 1e-20 | 31.08% (251) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3168 | - | 1e-19 | 27.76% (245) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4185 | - | 3e-18 | 27.53% (247) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2592|M.marinum_M ----MDEATPARQLLTDRVAVVT------GGAGGIGAATSRLFAQHGAQV
MUL_3168|M.ulcerans_Agy99 ------------------MAVVA------GGAGGIGAATSRLFAQHGAQV
MAV_3012|M.avium_104 ----MTQHKHFDPLLSDRVAVVT------GGGGGIGAATARLFAEHGAHV
Mb1519|M.bovis_AF2122/97 ---------------MTATATEG------AKPPFVSRSVLVTGGNRGIGL
Rv1483|M.tuberculosis_H37Rv ---------------MTATATEG------AKPPFVSRSVLVTGGNRGIGL
MLBr_01807|M.leprae_Br4923 ---------------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGL
Mflv_1258|M.gilvum_PYR-GCK --------------MVSRVAVVT------GGASGLGEAICAGLAADGHRV
Mvan_4185|M.vanbaalenii_PYR-1 ---------------MTRVAVVT------GGASGMGEATCHELGRRGCKV
MAB_2032|M.abscessus_ATCC_1997 ---------------MSGKEFEGQVALVTGASRGIGRSIALALAEHGADI
TH_2552|M.thermoresistible__bu -------------VLSDSVALIT------GASGGIGRVLARRYAQRGARV
MSMEG_4055|M.smegmatis_MC2_155 MNITPTTTTPATVRGNGRIALIT------GASRGIGAASAALFGQRGYRV
. :. . * :
MMAR_2592|M.marinum_M VIADID-AELAHR---TVDEIGGA--AWVVGTDVRDADQVSALAQRVLDR
MUL_3168|M.ulcerans_Agy99 VIADID-AELAHR---TVDEIGGA--AWVVGTDVRDADQVSALAQRVLDR
MAV_3012|M.avium_104 VIADID-AELADETASTIAASGGS--AHPITADVRNAAEVTHFARTVLDR
Mb1519|M.bovis_AF2122/97 AIAQRL-AADGHKVAVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEH
Rv1483|M.tuberculosis_H37Rv AIAQRL-AADGHKVAVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEH
MLBr_01807|M.leprae_Br4923 AVARRL-VADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEH
Mflv_1258|M.gilvum_PYR-GCK AVLDLD-ADAANRVAASLRGNGAS--AVGVAVDVSDEDAVVRAFDAVRTE
Mvan_4185|M.vanbaalenii_PYR-1 AVLDLD-GQAAQRVAEELRGDGVP--ALGVAADVTDRAAVEDAFAKVRTE
MAB_2032|M.abscessus_ATCC_1997 ALHYGN-SKPAAEEVAEKIS-ALGRRVLLCQGDIADPAVPELLADTVHAE
TH_2552|M.thermoresistible__bu ALVARR-RDELNVTAAAVTEAGGE--ALVLVADIRDETQCADAVAATVAR
MSMEG_4055|M.smegmatis_MC2_155 AVHHEHNAIEAHHVADAINDHGGD--ALVVQADLTRAEDVAEMTDAITHH
.: *: .
MMAR_2592|M.marinum_M YGRVDILVNNVGHWLRHPGNFVDTDPQLWDELYRVNLHH-VLLATHAFLP
MUL_3168|M.ulcerans_Agy99 YGRLDILVNNVGHWLRHPGNFVDTDPQLWDELYRVNLHH-VLLATHAFLP
MAV_3012|M.avium_104 YGRIDVLVNNVGHWLRHPGGFADTDPQLWDELYRINLHH-VFLVTHAFLP
Mb1519|M.bovis_AF2122/97 QGPVEVLVSNAG--LSADAFLMRMTEEKFEKVINANLTG-AFRVAQRASR
Rv1483|M.tuberculosis_H37Rv QGPVEVLVSNAG--LSADAFLMRMTEEKFEKVINANLTG-AFRVAQRASR
MLBr_01807|M.leprae_Br4923 QGPVEVLVANAG--ITSDMLIMRMSEEQFQKVIDVNLTG-VFRVAKLASR
Mflv_1258|M.gilvum_PYR-GCK FGPVEILVTSAA--IGGFTRFDKITLDEWNRYLAVNLTG-TFLSIRAALS
Mvan_4185|M.vanbaalenii_PYR-1 LGPVHILVTSAG--LVDFAPFLEISPDRWQRLIEVNLNG-TFHCAQVAIP
MAB_2032|M.abscessus_ATCC_1997 FGRIDVLVNNAG--THGAGLLLDIAPDYLEETVATNLLG-PIRMTKAVVA
TH_2552|M.thermoresistible__bu WGRLDVLVNNAA-VPGSDQSVAEATVDNWNQVLATNLVAPMVLSREALCQ
MSMEG_4055|M.smegmatis_MC2_155 WGPVEVLIHDGR-RPYERTSFAALSIDRLEHAVAQELRA-AFLVTKAVIP
* :.:*: . . : :. :* . .
MMAR_2592|M.marinum_M AMIEQHGGAIVNVSSVEGLRGYPEDPVYAAFKAAVIHFTRSLAVQVGNHG
MUL_3168|M.ulcerans_Agy99 AMIEQHGGAIVNVSSVEGLRGYPEDPVYAAFKAAVIHFTHSLAVQVGNHG
MAV_3012|M.avium_104 TMIDRGAGAIVNVSSVEGLRGYPEDPVYAAFKAAVIGFTRSLAVQVGNHG
Mb1519|M.bovis_AF2122/97 SMQRNKFGRMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKAN
Rv1483|M.tuberculosis_H37Rv SMQRNKFGRMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKAN
MLBr_01807|M.leprae_Br4923 NMIKQRFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRS
Mflv_1258|M.gilvum_PYR-GCK DMVAAQWGRVVTISSAAGQQGAPRQGHYSATKGGVIAMTKTVARDYARHG
Mvan_4185|M.vanbaalenii_PYR-1 DMLAAGWGRIVMISSSSAQRGSPGMAHYAASKGALISFTRSLAREYGPAG
MAB_2032|M.abscessus_ATCC_1997 HMLGQRYGRIINISSVAADKPDSGQSTYAATKGGLESFTKAIAVEFASRN
TH_2552|M.thermoresistible__bu AMIPAGSGNIQFLSSAAARNVAPGKAHYAAAKLALSALGQTLALEVGGTG
MSMEG_4055|M.smegmatis_MC2_155 AMIAGDYGRLVYLSVAHSRLPQDKRIVEGTAKAALDQFVRYLAQELAPHG
* * :. . .: * .: : : :* : . .
MMAR_2592|M.marinum_M VRINAIAPDVTESLQVP-------YSQWLSDA-EQTQWPGWVPVGRMGVP
MUL_3168|M.ulcerans_Agy99 VRINAIAPDVTESLQVP-------YSQWLSDA-EQTQWPGWVPVGRMGVP
MAV_3012|M.avium_104 VRVNAVAPDVTESLQVP-------YSQWLSAE-EQSQWPRWVPVGRMGLP
Mb1519|M.bovis_AF2122/97 VTANVVAPGYIDTDMTR-------ALDER----IQQGALQFIPAKRVGTP
Rv1483|M.tuberculosis_H37Rv VTANVVAPGYIDTDMTR-------ALDER----IQQGALQFIPAKRVGTP
MLBr_01807|M.leprae_Br4923 ITANVVAPGFIDTEMTR-------AMDSK----YQEAALQAIPLGRIGAV
Mflv_1258|M.gilvum_PYR-GCK ITANSLPPFAIETPMLR-------RQQSEGKLPPDEFLTQAIPAGRVGAP
Mvan_4185|M.vanbaalenii_PYR-1 ITVNNVPPSGIETPMQH-------QSQAAGFLPPNEQMAASIPVGHLGTG
MAB_2032|M.abscessus_ATCC_1997 IISNAVAPGVVYTDMAE-------ITRTHVP-ATFERLKAQILAKDFAKP
TH_2552|M.thermoresistible__bu IRVNTLVVGSVEGELLDRYVARRAAADGVSPDEVLSGLARSTKLGRLISP
MSMEG_4055|M.smegmatis_MC2_155 IPANLVAPGNVAGVDAG---------REAWTDDELWVLGTANTPARLVLP
: * : .
MMAR_2592|M.marinum_M EDQARVILFLACELSAFVTGHTIPTDGGTAAAGGWFRSSRRPDREWTNRP
MUL_3168|M.ulcerans_Agy99 EDQARVILFLACELSAFVTGHTIPTDGGTAAAGGWFRSSRRPDREWTNRP
MAV_3012|M.avium_104 EDQARVILFLASDCSSFITGHTIPTDGGTTAAGGWFRSSRRPGREWTNRP
Mb1519|M.bovis_AF2122/97 AEVAGVVSFLASEDASYISGAVIPVDGGMGMGH-----------------
Rv1483|M.tuberculosis_H37Rv AEVAGVVSFLASEDASYISGAVIPVDGGMGMGH-----------------
MLBr_01807|M.leprae_Br4923 EEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-----------------
Mflv_1258|M.gilvum_PYR-GCK SDVAAVCSFLCSDAAGYVTGQVIGVNGGAVL-------------------
Mvan_4185|M.vanbaalenii_PYR-1 DDIAAAVGFLCSEEAGFITGQTLGVNGGSVMA------------------
MAB_2032|M.abscessus_ATCC_1997 EIVADAVLYLASPHNTYITGEVLHIDGGYKMK------------------
TH_2552|M.thermoresistible__bu EEVADVSLWLASDAASAITGQDIFVTGG----------------------
MSMEG_4055|M.smegmatis_MC2_155 GDVARTVEFFASDDCVITTGHYAPVNAGLAVR------------------
* . ::.. :* .*
MMAR_2592|M.marinum_M IAP
MUL_3168|M.ulcerans_Agy99 IAP
MAV_3012|M.avium_104 ADP
Mb1519|M.bovis_AF2122/97 ---
Rv1483|M.tuberculosis_H37Rv ---
MLBr_01807|M.leprae_Br4923 ---
Mflv_1258|M.gilvum_PYR-GCK ---
Mvan_4185|M.vanbaalenii_PYR-1 ---
MAB_2032|M.abscessus_ATCC_1997 ---
TH_2552|M.thermoresistible__bu ---
MSMEG_4055|M.smegmatis_MC2_155 ---