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GTCPHSTARPALITGGGRGIGRAIAIRLAGEGARVGVHYGTNADTAEQTAQLIRDKGGDAFTVRAQLGVP GDAAALWQAFDRHADGLDILVNNAGILGGRIPFADLTEQTYDEVFAVNTRAPFFITQHGLSRLRDHGRII NVSTRFTHGGRMPELMAYAMSKAALDSFTATLAKEVAPRGITVNAVGPGTTETDMNAERLSTPEGRAAIA AQSPFNRVAQADDISGVVAFLASDDARWITGQWLDASGGSML*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2029 | - | - | 100% (253) | 3-ketoacyl-ACP/CoA redutase |
| M. smegmatis MC2 155 | MSMEG_5300 | - | 4e-38 | 40.33% (243) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_4351 | - | 2e-32 | 34.44% (241) | oxidoreductase YjgI |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 3e-25 | 33.33% (252) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4818 | - | 7e-31 | 37.65% (247) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1350 | fabG | 3e-25 | 33.33% (252) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 9e-23 | 30.24% (248) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0827 | - | 5e-35 | 39.43% (246) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_0629 | - | 1e-25 | 35.95% (242) | dehydrogenase |
| M. avium 104 | MAV_1395 | - | 1e-29 | 33.74% (246) | 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3122 | - | 2e-30 | 34.98% (243) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 3e-25 | 34.98% (243) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_5843 | - | 9e-35 | 35.20% (250) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2029|M.smegmatis_MC2_155 ----------------MGTCPHSTARPALITGGGRGIGRAIAIRLAGEGA
TH_3122|M.thermoresistible__bu -----------------------------VAAGAKNLGGLISTTLAERGV
Mflv_4818|M.gilvum_PYR-GCK -----------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYALAGA
MMAR_0629|M.marinum_M ----------------------MAGLTALITGATSGIGRATAHGLAELGA
MAB_0827|M.abscessus_ATCC_1997 ------------------MTSPLKSRRAFVTGGSRGIGAGIVRRLAEDGA
Mvan_5843|M.vanbaalenii_PYR-1 -----------------MSTAPLAGKRALVTGGSRGIGAEIVRRLAADGA
Mb1385|M.bovis_AF2122/97 -------MASLLN-----------ARTAVITGGAQGLGLAIGQRFVAEGA
Rv1350|M.tuberculosis_H37Rv -------MASLLN-----------ARTAVITGGAQGLGLAIGQRFVAEGA
MLBr_01807|M.leprae_Br4923 ----MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGH
MAV_1395|M.avium_104 --------------------------MAVVTGGGSGIGRAIVERLAHDGH
MUL_0315|M.ulcerans_Agy99 MRPDSSPSWC--------------TITSVVTGGASGIGLAIARRLSADGT
::.. .:* *
MSMEG_2029|M.smegmatis_MC2_155 RVGVHYGTNADT--AEQTAQLIRDKGGDAFTVRAQLGVPGDAAALWQAFD
TH_3122|M.thermoresistible__bu NVAVHYHSAATEPDADKTVAAVEATGARAIKVQGDLTVPANVTRLFDATV
Mflv_4818|M.gilvum_PYR-GCK RVVVASRKADAC---EQAAHHLRELGAQAIGVPTHLGQVDDLGALVERTV
MMAR_0629|M.marinum_M TVLVSGRDEARG---REVVDEVTARGGRGIFLAAELRDVTGVRNLATAAA
MAB_0827|M.abscessus_ATCC_1997 RVVFTYSSSVQQ--AADVVDDINEDGGWARAVKADVADPDQLGAAIGQAA
Mvan_5843|M.vanbaalenii_PYR-1 AVAFTYAASAAH--AEKVVAEVAASGGEAVAIRADSADPTQVADAVEQTV
Mb1385|M.bovis_AF2122/97 RVVLGDVNLEAT---EVAAKRLGGDDV-ALAVRCDVTQADDVDILIRTAV
Rv1350|M.tuberculosis_H37Rv RVVLGDVNLEAT---EVAAKRLGGDDV-ALAVRCDVTQADDVDILIRTAV
MLBr_01807|M.leprae_Br4923 RVAVTHR---AS---VVPDWFFG--------VECDVTDNDAIGAAFKAVE
MAV_1395|M.avium_104 RVAVLDVNEEAA---EKVAARVAADGAHAIAVPTDVAESASVAAAFESVR
MUL_0315|M.ulcerans_Agy99 DVATLDLKTP--------------DGG--LAFSADVTNRSQVDAALAAIR
* . .
MSMEG_2029|M.smegmatis_MC2_155 RHADG-LDILVNNAGILGGRIPFADLTEQTYDEVFAVNTRAPFFITQHGL
TH_3122|M.thermoresistible__bu EAFGG-VDIAVNTVGRVL-RKPIVETTEAEYDAMFDINAKAAYFFLQEAG
Mflv_4818|M.gilvum_PYR-GCK AEFGG-LDVLVNNAANPL-AQPFGHMTVDALSKSFEVNLQGPVMLTQEAL
MMAR_0629|M.marinum_M DAGAGKVDILINSAGAFP-FGPTADTSPDDFDAVFALNVRAPYFLVGALA
MAB_0827|M.abscessus_ATCC_1997 EELGG-LDILVNNAGILS-IGDVDTATLADFDEIVAVNVRAVFAGIKAAS
Mvan_5843|M.vanbaalenii_PYR-1 AELGG-LDILVNNSAVAH-IAPIDDFPAEEFDRLVAINIGGVYWAVRSAI
Mb1385|M.bovis_AF2122/97 ERFGG-LDVMVNNAGITR-DATMRTMTEEQFDQVIAVHLKGTWNGTRLAA
Rv1350|M.tuberculosis_H37Rv ERFGG-LDVMVNNAGITR-DATMRTMTEEQFDQVIAVHLKGTWNGTRLAA
MLBr_01807|M.leprae_Br4923 EHQGP-VEVLVANAGITS-DMLIMRMSEEQFQKVIDVNLTGVFRVAKLAS
MAV_1395|M.avium_104 RALGS-VQVLVTSAAITG-FKPFAEITIEDWNRHLAVNLTGTFLCLQAAL
MUL_0315|M.ulcerans_Agy99 QRLGP-VTILVNAAGLDG-FKRFSNITFEDWQRVIDVNLNGVFHTIQAVL
: : : . . . . :: .
MSMEG_2029|M.smegmatis_MC2_155 SRLRD-HGRIINVSTRFTHGGRMPELMAYAMSKAALDSFTATLAKEVAPR
TH_3122|M.thermoresistible__bu KRLND-GGSVVTILTALLAA-FTDGYSTYAGAKSPVEHFTRAAAKEFAPR
Mflv_4818|M.gilvum_PYR-GCK PHLKASDHAAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHD
MMAR_0629|M.marinum_M PTMAKRGRGSIVNVTTMVAEFGAAGTGLYGASKAAIALLTKSWAAEYGPS
MAB_0827|M.abscessus_ATCC_1997 PHLTE-GGRIVTIGSINGDSSPTANLSLYSMTKAAVAGLTRGLAREFGPR
Mvan_5843|M.vanbaalenii_PYR-1 RYLSE-GARIINIGSINADRIPGPGLSVYGMTKGAVSSFTRGLARDLGPR
Mb1385|M.bovis_AF2122/97 AIMRERKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHL
Rv1350|M.tuberculosis_H37Rv AIMRERKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHL
MLBr_01807|M.leprae_Br4923 RNMIKQRFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSR
MAV_1395|M.avium_104 PDMVEAGWGRVVTISSTAAQTGSPRQGHYSASKGGVIALTRTIALEYAAH
MUL_0315|M.ulcerans_Agy99 PDMVAAGWGRIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPS
: * *. : :: * :
MSMEG_2029|M.smegmatis_MC2_155 GITVNAVGPGTTETDMNAERLSTPEG--RAAIAAQSPFNRVAQADDISGV
TH_3122|M.thermoresistible__bu QISVNNVAPGPMDTPFFYG-QETPER--VTFHKSQGLGNRLTRIEDIAPL
Mflv_4818|M.gilvum_PYR-GCK GIRVNALAPGPVDTDMMRK--NPQEA--IDGMVGGTLVGRLASADEMVGA
MMAR_0629|M.marinum_M GVRVNAVSPGPTRTEGTVE---MGEA--LDQLAAAAPAGRPADPTEIAST
MAB_0827|M.abscessus_ATCC_1997 GITINNVQPGPIGTDMNPE---DGQL--ADILRPNIAVGRYGQPRDIASL
Mvan_5843|M.vanbaalenii_PYR-1 GITVNNVQPGPIDTDANPD---DGAF--AESLKQVVAQGRYGHTSDVASL
Mb1385|M.bovis_AF2122/97 GIRVNAIAPGLIRSAMTEAMPQR----IWDQKLAEVPMGRAGEPSEVASV
Rv1350|M.tuberculosis_H37Rv GIRVNAIAPGLIRSAMTEAMPQR----IWDQKLAEVPMGRAGEPSEVASV
MLBr_01807|M.leprae_Br4923 SITANVVAPGFIDTEMTRAMDSK----YQEAALQAIPLGRIGAVEEIAGA
MAV_1395|M.avium_104 GITANTVPPFSVDTPMLRAAQEAGNLPPVKYLAKASPVGRLGTGEDIAAA
MUL_0315|M.ulcerans_Agy99 GITVNAVPPGFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAA
: * : * : * ::
MSMEG_2029|M.smegmatis_MC2_155 VAFLASDDARWITGQWLDASGGSML--
TH_3122|M.thermoresistible__bu VAFLT-DEGHWITGQTIFANGGYTTR-
Mflv_4818|M.gilvum_PYR-GCK ALLLTSDAGSYITGQVIIADGGGTPR-
MMAR_0629|M.marinum_M IVYLASDAASFIHGAVVPVDGGRAAV-
MAB_0827|M.abscessus_ATCC_1997 VSYLVSDEAWYITGTAINIDGGFTA--
Mvan_5843|M.vanbaalenii_PYR-1 VSFLAGPESGYITGAHLNVDGGFTV--
Mb1385|M.bovis_AF2122/97 AVFLASDLSSYMTGTVLDVTGGRFI--
Rv1350|M.tuberculosis_H37Rv AVFLASDLSSYMTGTVLDVTGGRFI--
MLBr_01807|M.leprae_Br4923 VSFLASEDAGYISGAVIPVDGGLGMGH
MAV_1395|M.avium_104 CAFLCSDEAGYITGQIIGVNGGEVI--
MUL_0315|M.ulcerans_Agy99 CAFLVSEEAGYITGQILGVNGGRNT--
* . :: * : **