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M. gilvum PYR-GCK Mflv_1258 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 1311589 - 1312335
length: 248

VVSRVAVVTGGASGLGEAICAGLAADGHRVAVLDLDADAANRVAASLRGNGASAVGVAVDVSDEDAVVRA
FDAVRTEFGPVEILVTSAAIGGFTRFDKITLDEWNRYLAVNLTGTFLSIRAALSDMVAAQWGRVVTISSA
AGQQGAPRQGHYSATKGGVIAMTKTVARDYARHGITANSLPPFAIETPMLRRQQSEGKLPPDEFLTQAIP
AGRVGAPSDVAAVCSFLCSDAAGYVTGQVIGVNGGAVL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1258--100% (248)short-chain dehydrogenase/reductase SDR
M. gilvum PYR-GCKMflv_2469-2e-7253.25% (246) short-chain dehydrogenase/reductase SDR
M. gilvum PYR-GCKMflv_2501-2e-5243.33% (240) short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1519fabG12e-4140.56% (249) 3-oxoacyl-
M. tuberculosis H37RvRv1483fabG12e-4140.56% (249) 3-oxoacyl-
M. leprae Br4923MLBr_01807fabG14e-4138.96% (249) 3-oxoacyl-
M. abscessus ATCC 19977MAB_2723c-2e-3939.02% (246) 3-oxoacyl-
M. marinum MMMAR_4715-3e-5445.45% (242) 3-oxoacyl-
M. avium 104MAV_1395-8e-8761.89% (244) 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_0527-1e-10173.68% (247) 2-hydroxycyclohexnecarboxyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_2435-2e-9873.75% (240) PUTATIVE short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_0315fabG25e-5445.42% (240) 3-oxoacyl-
M. vanbaalenii PYR-1Mvan_4185-8e-7353.85% (247) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1258|M.gilvum_PYR-GCK          ------------------MVSRVAVVTGGASGLGEAICAGLAADGHRVAV
MSMEG_0527|M.smegmatis_MC2_155      -------------------MSRVAAVTGAGSGVGRATALQLARDGHRVAV
TH_2435|M.thermoresistible__bu      -------------------------VTGGASGLGRAIAARLGDDGHRVAV
MAV_1395|M.avium_104                ----------------------MAVVTGGGSGIGRAIVERLAHDGHRVAV
Mvan_4185|M.vanbaalenii_PYR-1       -------------------MTRVAVVTGGASGMGEATCHELGRRGCKVAV
MMAR_4715|M.marinum_M               ----------MK----------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99           ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
Mb1519|M.bovis_AF2122/97            MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
Rv1483|M.tuberculosis_H37Rv         MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_2723c|M.abscessus_ATCC_199      MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAV
                                                             ***.  *:* *    *   *  **.

Mflv_1258|M.gilvum_PYR-GCK          LDLDADAANRVAASLRGNGASAVGVAVDVSDEDAVVRAFDAVRTEFGPVE
MSMEG_0527|M.smegmatis_MC2_155      MDLDGQAAEEAAAKIESHGGRALAVAVDVADESAVAAGFEAARQAFGPIG
TH_2435|M.thermoresistible__bu      LDIDHAAAEQTAAELRAHGGDAVAVGADVADQDAVHDAFAAIRGSLGPVH
MAV_1395|M.avium_104                LDVNEEAAEKVAARVAADGAHAIAVPTDVAESASVAAAFESVRRALGSVQ
Mvan_4185|M.vanbaalenii_PYR-1       LDLDGQAAQRVAEELRGDGVPALGVAADVTDRAAVEDAFAKVRTELGPVH
MMAR_4715|M.marinum_M               LDLKTPDGE-------------LAFSADVTNRSQVDAALTAIRQRLGPVT
MUL_0315|M.ulcerans_Agy99           LDLKTPDGG-------------LAFSADVTNRSQVDAALAAIRQRLGPVT
Mb1519|M.bovis_AF2122/97            THRGSGAPKG-----------LFGVECDVTDSDAVDRAFTAVEEHQGPVE
Rv1483|M.tuberculosis_H37Rv         THRGSGAPKG-----------LFGVECDVTDSDAVDRAFTAVEEHQGPVE
MLBr_01807|M.leprae_Br4923          THRASVVPDW-----------FFGVECDVTDNDAIGAAFKAVEEHQGPVE
MAB_2723c|M.abscessus_ATCC_199      THRGSGAPEG-----------LLGVQCDITDNDQIDAAFKEVEEKQGPVE
                                     .                    ...  *:::   :  .:   .   *.: 

Mflv_1258|M.gilvum_PYR-GCK          ILVTSAAIGGFTRFDKITLDEWNRYLAVNLTGTFLSIRAALSDMVAAQWG
MSMEG_0527|M.smegmatis_MC2_155      IVVTSAAMGGFTRFDKITLDEWNRYLAVNLTGTFLCIRAALPDMVKAQWG
TH_2435|M.thermoresistible__bu      ILVTSAAIAGFTRFDEITLDEWNRYLAVNLTGTFLCVQAALTDMVADGWG
MAV_1395|M.avium_104                VLVTSAAITGFKPFAEITIEDWNRHLAVNLTGTFLCLQAALPDMVEAGWG
Mvan_4185|M.vanbaalenii_PYR-1       ILVTSAGLVDFAPFLEISPDRWQRLIEVNLNGTFHCAQVAIPDMLAAGWG
MMAR_4715|M.marinum_M               ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
MUL_0315|M.ulcerans_Agy99           ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
Mb1519|M.bovis_AF2122/97            VLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFG
Rv1483|M.tuberculosis_H37Rv         VLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFG
MLBr_01807|M.leprae_Br4923          VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG
MAB_2723c|M.abscessus_ATCC_199      VLVANAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFG
                                    ::*  *.:     : .:: : : : : .** *.*   : .  .*    :*

Mflv_1258|M.gilvum_PYR-GCK          RVVTISSAAGQQGAPRQGHYSATKGGVIAMTKTVARDYARHGITANSLPP
MSMEG_0527|M.smegmatis_MC2_155      RIVTISSAAGQRGAPAQGHYSATKGGVIAMTKTLALDYAAKGITANTIPP
TH_2435|M.thermoresistible__bu      RIVTISSAAGQQGAHRQGHYAATKGGVIALTKTVALDYAAKGITANTVPP
MAV_1395|M.avium_104                RVVTISSTAAQTGSPRQGHYSASKGGVIALTRTIALEYAAHGITANTVPP
Mvan_4185|M.vanbaalenii_PYR-1       RIVMISSSSAQRGSPGMAHYAASKGALISFTRSLAREYGPAGITVNNVPP
MMAR_4715|M.marinum_M               RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP
MUL_0315|M.ulcerans_Agy99           RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP
Mb1519|M.bovis_AF2122/97            RMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP
Rv1483|M.tuberculosis_H37Rv         RMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP
MLBr_01807|M.leprae_Br4923          RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAP
MAB_2723c|M.abscessus_ATCC_199      RLIFMGSVAGQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVVAP
                                    * : :.*     *     :* *:*..: .:::::: : .  .:*.* :.*

Mflv_1258|M.gilvum_PYR-GCK          FAIETPMLRRQQSEGKLPPDEFLTQAIPAGRVGAPSDVAAVCSFLCSDAA
MSMEG_0527|M.smegmatis_MC2_155      FVIDTPMLREQQAAGLLPQAEHLTKAIPAGRLGSGDDVAAMCSFLCSDAA
TH_2435|M.thermoresistible__bu      FVIDSPMLREQQRRGTLPPAEYLTRAIPMGRLGVAEDVAAVCSFLCSDAA
MAV_1395|M.avium_104                FSVDTPMLRAAQEAGNLPPVKYLAKASPVGRLGTGEDIAAACAFLCSDEA
Mvan_4185|M.vanbaalenii_PYR-1       SGIETPMQHQSQAAGFLPPNEQMAASIPVGHLGTGDDIAAAVGFLCSEEA
MMAR_4715|M.marinum_M               GFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEA
MUL_0315|M.ulcerans_Agy99           GFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEA
Mb1519|M.bovis_AF2122/97            GYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDA
Rv1483|M.tuberculosis_H37Rv         GYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDA
MLBr_01807|M.leprae_Br4923          GFIDTEMTRAMDSK----YQEAALQAIPLGRIGAVEEIAGAVSFLASEDA
MAB_2723c|M.abscessus_ATCC_199      GFIDTDMTRELGEK----HVETALTAIPMGRIGEPSEVAGVVSWLASPDA
                                      ::: * :           :      *  ::*   ::*.  .:* *  *

Mflv_1258|M.gilvum_PYR-GCK          GYVTGQVIGVNGGAVL--
MSMEG_0527|M.smegmatis_MC2_155      GYVTGQVIGVNGGAVL--
TH_2435|M.thermoresistible__bu      GYLTGQVIGVNGGAIR--
MAV_1395|M.avium_104                GYITGQIIGVNGGEVI--
Mvan_4185|M.vanbaalenii_PYR-1       GFITGQTLGVNGGSVMA-
MMAR_4715|M.marinum_M               GYITGQILGVNGGRNT--
MUL_0315|M.ulcerans_Agy99           GYITGQILGVNGGRNT--
Mb1519|M.bovis_AF2122/97            SYISGAVIPVDGGMGMGH
Rv1483|M.tuberculosis_H37Rv         SYISGAVIPVDGGMGMGH
MLBr_01807|M.leprae_Br4923          GYISGAVIPVDGGLGMGH
MAB_2723c|M.abscessus_ATCC_199      AYVSGAVIPVDGGLGMGH
                                    .:::*  : *:**