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VVSRVAVVTGGASGLGEAICAGLAADGHRVAVLDLDADAANRVAASLRGNGASAVGVAVDVSDEDAVVRA FDAVRTEFGPVEILVTSAAIGGFTRFDKITLDEWNRYLAVNLTGTFLSIRAALSDMVAAQWGRVVTISSA AGQQGAPRQGHYSATKGGVIAMTKTVARDYARHGITANSLPPFAIETPMLRRQQSEGKLPPDEFLTQAIP AGRVGAPSDVAAVCSFLCSDAAGYVTGQVIGVNGGAVL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1258 | - | - | 100% (248) | short-chain dehydrogenase/reductase SDR |
M. gilvum PYR-GCK | Mflv_2469 | - | 2e-72 | 53.25% (246) | short-chain dehydrogenase/reductase SDR |
M. gilvum PYR-GCK | Mflv_2501 | - | 2e-52 | 43.33% (240) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1519 | fabG1 | 2e-41 | 40.56% (249) | 3-oxoacyl- |
M. tuberculosis H37Rv | Rv1483 | fabG1 | 2e-41 | 40.56% (249) | 3-oxoacyl- |
M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-41 | 38.96% (249) | 3-oxoacyl- |
M. abscessus ATCC 19977 | MAB_2723c | - | 2e-39 | 39.02% (246) | 3-oxoacyl- |
M. marinum M | MMAR_4715 | - | 3e-54 | 45.45% (242) | 3-oxoacyl- |
M. avium 104 | MAV_1395 | - | 8e-87 | 61.89% (244) | 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase |
M. smegmatis MC2 155 | MSMEG_0527 | - | 1e-101 | 73.68% (247) | 2-hydroxycyclohexnecarboxyl-CoA dehydrogenase |
M. thermoresistible (build 8) | TH_2435 | - | 2e-98 | 73.75% (240) | PUTATIVE short-chain dehydrogenase/reductase SDR |
M. ulcerans Agy99 | MUL_0315 | fabG2 | 5e-54 | 45.42% (240) | 3-oxoacyl- |
M. vanbaalenii PYR-1 | Mvan_4185 | - | 8e-73 | 53.85% (247) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1258|M.gilvum_PYR-GCK ------------------MVSRVAVVTGGASGLGEAICAGLAADGHRVAV MSMEG_0527|M.smegmatis_MC2_155 -------------------MSRVAAVTGAGSGVGRATALQLARDGHRVAV TH_2435|M.thermoresistible__bu -------------------------VTGGASGLGRAIAARLGDDGHRVAV MAV_1395|M.avium_104 ----------------------MAVVTGGGSGIGRAIVERLAHDGHRVAV Mvan_4185|M.vanbaalenii_PYR-1 -------------------MTRVAVVTGGASGMGEATCHELGRRGCKVAV MMAR_4715|M.marinum_M ----------MK----------TAVVTGGASGIGLAIARRLRADGIDVAT MUL_0315|M.ulcerans_Agy99 ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT Mb1519|M.bovis_AF2122/97 MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV Rv1483|M.tuberculosis_H37Rv MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV MAB_2723c|M.abscessus_ATCC_199 MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAV ***. *:* * * * **. Mflv_1258|M.gilvum_PYR-GCK LDLDADAANRVAASLRGNGASAVGVAVDVSDEDAVVRAFDAVRTEFGPVE MSMEG_0527|M.smegmatis_MC2_155 MDLDGQAAEEAAAKIESHGGRALAVAVDVADESAVAAGFEAARQAFGPIG TH_2435|M.thermoresistible__bu LDIDHAAAEQTAAELRAHGGDAVAVGADVADQDAVHDAFAAIRGSLGPVH MAV_1395|M.avium_104 LDVNEEAAEKVAARVAADGAHAIAVPTDVAESASVAAAFESVRRALGSVQ Mvan_4185|M.vanbaalenii_PYR-1 LDLDGQAAQRVAEELRGDGVPALGVAADVTDRAAVEDAFAKVRTELGPVH MMAR_4715|M.marinum_M LDLKTPDGE-------------LAFSADVTNRSQVDAALTAIRQRLGPVT MUL_0315|M.ulcerans_Agy99 LDLKTPDGG-------------LAFSADVTNRSQVDAALAAIRQRLGPVT Mb1519|M.bovis_AF2122/97 THRGSGAPKG-----------LFGVECDVTDSDAVDRAFTAVEEHQGPVE Rv1483|M.tuberculosis_H37Rv THRGSGAPKG-----------LFGVECDVTDSDAVDRAFTAVEEHQGPVE MLBr_01807|M.leprae_Br4923 THRASVVPDW-----------FFGVECDVTDNDAIGAAFKAVEEHQGPVE MAB_2723c|M.abscessus_ATCC_199 THRGSGAPEG-----------LLGVQCDITDNDQIDAAFKEVEEKQGPVE . ... *::: : .: . *.: Mflv_1258|M.gilvum_PYR-GCK ILVTSAAIGGFTRFDKITLDEWNRYLAVNLTGTFLSIRAALSDMVAAQWG MSMEG_0527|M.smegmatis_MC2_155 IVVTSAAMGGFTRFDKITLDEWNRYLAVNLTGTFLCIRAALPDMVKAQWG TH_2435|M.thermoresistible__bu ILVTSAAIAGFTRFDEITLDEWNRYLAVNLTGTFLCVQAALTDMVADGWG MAV_1395|M.avium_104 VLVTSAAITGFKPFAEITIEDWNRHLAVNLTGTFLCLQAALPDMVEAGWG Mvan_4185|M.vanbaalenii_PYR-1 ILVTSAGLVDFAPFLEISPDRWQRLIEVNLNGTFHCAQVAIPDMLAAGWG MMAR_4715|M.marinum_M ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG MUL_0315|M.ulcerans_Agy99 ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG Mb1519|M.bovis_AF2122/97 VLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFG Rv1483|M.tuberculosis_H37Rv VLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFG MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG MAB_2723c|M.abscessus_ATCC_199 VLVANAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFG ::* *.: : .:: : : : : .** *.* : . .* :* Mflv_1258|M.gilvum_PYR-GCK RVVTISSAAGQQGAPRQGHYSATKGGVIAMTKTVARDYARHGITANSLPP MSMEG_0527|M.smegmatis_MC2_155 RIVTISSAAGQRGAPAQGHYSATKGGVIAMTKTLALDYAAKGITANTIPP TH_2435|M.thermoresistible__bu RIVTISSAAGQQGAHRQGHYAATKGGVIALTKTVALDYAAKGITANTVPP MAV_1395|M.avium_104 RVVTISSTAAQTGSPRQGHYSASKGGVIALTRTIALEYAAHGITANTVPP Mvan_4185|M.vanbaalenii_PYR-1 RIVMISSSSAQRGSPGMAHYAASKGALISFTRSLAREYGPAGITVNNVPP MMAR_4715|M.marinum_M RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP MUL_0315|M.ulcerans_Agy99 RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP Mb1519|M.bovis_AF2122/97 RMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP Rv1483|M.tuberculosis_H37Rv RMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP MLBr_01807|M.leprae_Br4923 RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAP MAB_2723c|M.abscessus_ATCC_199 RLIFMGSVAGQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVVAP * : :.* * :* *:*..: .:::::: : . .:*.* :.* Mflv_1258|M.gilvum_PYR-GCK FAIETPMLRRQQSEGKLPPDEFLTQAIPAGRVGAPSDVAAVCSFLCSDAA MSMEG_0527|M.smegmatis_MC2_155 FVIDTPMLREQQAAGLLPQAEHLTKAIPAGRLGSGDDVAAMCSFLCSDAA TH_2435|M.thermoresistible__bu FVIDSPMLREQQRRGTLPPAEYLTRAIPMGRLGVAEDVAAVCSFLCSDAA MAV_1395|M.avium_104 FSVDTPMLRAAQEAGNLPPVKYLAKASPVGRLGTGEDIAAACAFLCSDEA Mvan_4185|M.vanbaalenii_PYR-1 SGIETPMQHQSQAAGFLPPNEQMAASIPVGHLGTGDDIAAAVGFLCSEEA MMAR_4715|M.marinum_M GFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEA MUL_0315|M.ulcerans_Agy99 GFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSEEA Mb1519|M.bovis_AF2122/97 GYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDA Rv1483|M.tuberculosis_H37Rv GYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASEDA MLBr_01807|M.leprae_Br4923 GFIDTEMTRAMDSK----YQEAALQAIPLGRIGAVEEIAGAVSFLASEDA MAB_2723c|M.abscessus_ATCC_199 GFIDTDMTRELGEK----HVETALTAIPMGRIGEPSEVAGVVSWLASPDA ::: * : : * ::* ::*. .:* * * Mflv_1258|M.gilvum_PYR-GCK GYVTGQVIGVNGGAVL-- MSMEG_0527|M.smegmatis_MC2_155 GYVTGQVIGVNGGAVL-- TH_2435|M.thermoresistible__bu GYLTGQVIGVNGGAIR-- MAV_1395|M.avium_104 GYITGQIIGVNGGEVI-- Mvan_4185|M.vanbaalenii_PYR-1 GFITGQTLGVNGGSVMA- MMAR_4715|M.marinum_M GYITGQILGVNGGRNT-- MUL_0315|M.ulcerans_Agy99 GYITGQILGVNGGRNT-- Mb1519|M.bovis_AF2122/97 SYISGAVIPVDGGMGMGH Rv1483|M.tuberculosis_H37Rv SYISGAVIPVDGGMGMGH MLBr_01807|M.leprae_Br4923 GYISGAVIPVDGGLGMGH MAB_2723c|M.abscessus_ATCC_199 AYVSGAVIPVDGGLGMGH .:::* : *:**